• Journal of Pharmaceutical Investigation
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• v.14 no.3
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• pp.105-121
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• 1984

The bioavailability of rifampicin (brand A, B and C) was studied and the dissolution by foamed plastic rotating method and basket rotating method was also investigated. The results were as follows; 1. In the case of foamed plastic rotating method, it was revealed that dissolution rate of brand C was most rapid, but in the case of basket rotating method the results revealed that brand B was most rapid. Also it was observed that the dissolution rate in artificial gastric juice was more rapid than one in artificial intestinal juice, and that Avicel added in capsule increased additively the dissolution rate, particulary brand B. 2. Relative systemic availability by urine data showed that the results from all capsules filled with brand A, B and C were identical but in the case of the ripamficin capsules filled with Avicel, the results showed that Avicel increased the availability of brand A and B. 3. Area under serum concentration curve $(0{\sim}8hrs)$ was in order of $brand\;A{\fallingdotseq}brand\;C$ > brand B, but Avicel increased significantly the AUC of brand B and showed no effect in others. 4. Relative systemic availability calculated with excreted amount of rifampicin in urine was similar in each rifampicin capsules. In rifampicin (A) and rifampicin (B), Avicel which added in capsules appeared increasing tendency in urine excretion of rifampicin, but in rifampicin (C) it did not appeared. 5. Area under serum concentration curve $(0{\sim}8hrs)$ in rifampicin capsules was in order of $rifampicin(A){\fallingdotseq}rifampicin(C)$>rifampicin(B). In rifampicin (B) with Avicel capsules, area under serum concentration curve (0-8hrs.) increased significantly and in others insignificantly.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.8 s.239
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• pp.911-920
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• 2005

The present study investigates heat/mass transfer and flow characteristics in a ribbed rotating passage with turning region. The duct has an aspect ratio (W/H) of 0.5 and a hydraulic diameter ($D_h$) of 26.67 mm. Rib turbulators are attached in the parallel arrangement on the leading and trailing surfaces of the passage. The ribs have a rectangular cross section of 2 m (e) $\times$ 3 m (w) and an attack angle of $70^{\circ}$. The pitch-to-rib height ratio (p/e) is 7.5, and the rib height-to-hydraulic diameter ratio (e/$D_h$) is 0.075. The rotation number ranges from 0.0 to 0.20 while the Reynolds number is constant at 10,000. To verify the heat/mass transfer augmentation, internal flow structures are calculated for the same conditions using a commercial code FLUENT 6.1. The results show that a pair of vortex cells are generated due to the symmetric geometry of the rib arrangement, and heat/mass transfer is augmented up to $Sh/Sh_0=2.9$ averagely, which is higher than that of the cross-ribbed case presented in the previous study for the stationary case. With the passage rotation, the main flow in the first-pass deflects toward the trailing surface and the heat transfer is enhanced on the trailing surface. In the second-pass, the flow enlarges the vortex cell close to the leading surface, and the small vortex cell on the trailing surface side contracts to disappear as the passage rotates faster. At the highest rotation number ($R_O=0.20$), the turn-induced single vortex cell becomes identical regardless of the rib configuration so that similar local heat/mass transfer distributions are observed in the fuming region for the cross- and parallel-ribbed case.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.30 no.1
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• pp.55-65
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• 2016

This paper proposed a new control method which is capable of controlling circulating current considering current capacity of switching device. In the unbalanced voltage conditions, active power and reactive power have double line frequency. Thus, in order to provide active power without ripple, it is necessary to inject the negative sequence current components. However, when the negative current components is injected, it increases the total current flowing in the Arm, and in the Sub-module(SM) the current more than rated is impressed, which leads to destroy the system. Also, in impressing the circulating current reference of each arm, conventional control method impressed applicable $i_{dck}/3$ in the case of balanced voltage conditions. In the case of unbalanced conditions, as arm circulating current of three phase show difference due to the power impressed to each arm, reference of each arm is not identical. In this study, in the case of unbalanced voltage, within permitted current, the control method to decrease the ripple of active power is proposed, through circulating current control and current limitations. This control method has the advantage that calculates the maximum active power possible to generate capacity and impressed the current reference for that much. Also, in impressing circulating current reference, a new control method proposes to impress the reference from calculating active power of each phase. The proposed control method is verified through the simulation results, using the PSCAD/EMTDC.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.2 no.2
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• pp.262-266
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• 1999

Obstruction of the extrahepatic bile ducts is the most common cause of conjugated hyperbilirubinemia in early infancy. More than 90% of such obstructive lesions are accounted for by extrahepatic biliary atresia. A rare lesion is obstruction of the common duct by impacted, thickened secretions and bile. Bile plug syndrome is defined as extrahepatic obstruction of the bile ducts by bile sludge in term infants without anatomic abnormalities, congenital chemical defects of bile, or hepatocellular lesions. Obstruction of extrahepatic ducts by plugs of biliary material apperas to be due to the inspissation and precipitation of bile and mucus within the lumen of the ducts. Cholestasis and precipitation of bile develop in association with abnormal composition of bile in cystic fibrosis, hepatocellular damage, prolonged erythroblastic jaundice, altered biliary dynamics with total parenteral nutrition, gut dysfunction, diuretic therapy, exchange transfusions and perinatal hemolysis. In those cases, the term inspissated bile syndrome is used. The clinical and laboratory findings in bile plug syndrome are identical to those observed in biliary atresia and choledochal cyst. The diagnosis can be suspected based on the findings of clinical and laboratory examinations together with hepatobiliary imaging, ultrasonography, radionuclide scan and liver biopsy. We experienced a case of spontaneous resolution of bile plug syndrome in a 4-year-old girl. We report this case with brief review related literatures.

• Investigative and Clinical Urology
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• v.63 no.3
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• pp.334-340
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• 2022

Purpose The prevalence of catheter-associated urinary tract infections (CAUTIs) varies from 5% to 8.2%, and the risk of infection increases by 5% to 7% per day of primary indwelling. We investigated whether a novel biofilm inhibitory mechanism using an inhibitory silicone urethral catheter (a coated Foley catheter) can reduce CAUTIs compared to conventional non-coated Foley catheters. Materials and Methods This study prospectively analyzed the difference in the incidence of CAUTIs in patients who underwent radical cystectomy with an orthotopic neobladder for bladder cancer and received a coated or conventional non-coated catheter. Additionally, differences in bacterial colonization between the groups were analyzed using a catheter-tip bacterial culture test. Results Eighty-five patients were randomized into the "coated Foley catheter" group (abbreviated as "case" group; 41 patients) and a control group (44 patients). The two groups were identical except for their surgical history. The incidence of CAUTIs 2 weeks after radical cystectomy was 21.95% (case) and 27.27% (control), with no significant difference between the two groups. However, when the catheter was removed 2 weeks after surgery, the catheter tip culture test revealed significant bacterial colonies in 25 (60.98%) and 38 (86.36%) patients in the case and control group, respectively. No catheter-related postoperative side effects were observed in either group. Conclusions The incidence of CAUTIs in the two groups did not differ according to the catheter material. However, the catheter bacterial culture test showed that bacterial colonization was significantly suppressed on the Bi-Fi Free technology catheter, which comparatively inhibited biofilm formation.

• Journal of Korea Multimedia Society
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• v.19 no.2
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• pp.411-417
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• 2016

Since the development of Graphic Processing Unit (GPU) in 1999, the development speed of GPUs has become much faster than that of CPUs and currently, the computational power of GPUs exceeds CPUs dozens and hundreds times in terms of decimal calculations and costs much less. Owing to recent technological development of hardwares, general-purpose computing and utilization using GPUs are on the rise. Thus, in this paper, we have identified the elements to be considered for the Smart Grid Security. Focusing on a Performance Improvement of the Basic Algorithm for the Stateful Inspection to Detect DDoS Attacks using CUDA. In the program, we compared the search speeds of GPU against CPU while they search for the suffix trees. For the computation, the system constraints and specifications were made identical during the experiment. We were able to understand from the results of the experiment that the problem-solving capability improves when GPU is used. The other finding was that performance of the system had been enhanced when shared memory was used explicitly instead of a global memory as the volume of data became larger.

• 한국공간정보시스템학회:학술대회논문집
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• 2005.05a
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• pp.345-349
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• 2005

Massive amount of satellite image processing such asglobal/continental-level analysis and monitoring requires automated and speedy georegistration. There could be two major automated approaches: (1) rigid mathematical modeling using sensor model and ephemeris data; (2) heuristic co-registration approach with respect to existing reference image. In case of ETM+, the accuracy of the first approach is known as RMSE 250m, which is far below requested accuracy level for most of satellite image processing. On the other hands, the second approach is to find identical points between new image and reference image and use heuristic regression model for registration. The latter shows better accuracy but has problems with expensive computation. To improve efficiency of the coregistration approach, the author proposed a pre-qualified matching algorithm which is composed of feature extraction with canny operator and area matching algorithm with correlation coefficient. Throughout the pre-qualification approach, the computation time was significantly improved and make the registration accuracy is improved. A prototype was implemented and tested with the proposed algorithm. The performance test of 14 TM/ETM+ images in the U.S. showed: (1) average RMSE error of the approach was 0.47 dependent upon terrain and features; (2) the number average matching points were over 15,000; (3) the time complexity was 12 min per image with 3.2GHz Intel Pentium 4 and 1G Ram.

• Journal of the Korea Computer Graphics Society
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• v.6 no.3
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• pp.35-40
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• 2000

There are two problems in H.26X compression technique. One is compressing time in encoding process and the other is degradation of the decoded video quality due to high compression rate. For transferring moving pictures in real-time, it is required to adopt massively high compression. In this case, there are a lot of losses of an original video data and that results in degradation of quality. Especially degradation called by blocking artifact may be produced. The blocking artifact effect is produced by DCT-based coding techniques because they operate without considering correlation between pixels in block boundaries. So it represents discontinuity between adjacent blocks. This paper describes methods of quality compensation for H.26x decoded data and enhancing encoding speed for real-time operation. Our goal of the quality compensation is not to make the decoded video identical to a original video but to make it perceived better through human eyes. We suggest an algorithm that reduces block artifact and clears decoded video in decoder. To enhance encoding speed, we adopt new four-step search algorithm. As shown in the experimental result, the quality compensation provides better video quality because of reducing blocking artifact. And then new four-step search algorithm with $MMX^{TM}$ implementation improves encoding speed from 2.5 fps to 17 fps.

• The korean journal of orthodontics
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• v.43 no.3
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• pp.141-146
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• 2013

Objective: Bonding forces of brackets to enamel surfaces may be affected by the procedures used for bleaching and enamel etching. The aim of this study was to investigate the bonding strength of orthodontic brackets to laser-etched surfaces of bleached teeth. Methods: In a nonbleached control group, acid etching (group A) or Er:YAG laser application (group B) was performed prior to bracket bonding (n = 13 in each group). Similar surface treatments were performed at 1 day (groups C and D; n = 13 in each subgroup) or at 3 weeks (groups E and F; n = 13 in each subgroup) after 38% hydrogen peroxide bleaching in another set of teeth. The specimens were debonded after thermocycling. Results: Laser etching of bleached teeth resulted in clinically unacceptable low bonding strength. In the case of acid-etched teeth, waiting for 3 weeks before attachment of brackets to the bleached surfaces resulted in similar, but not identical, bond strength values as those obtained with nonbleached surfaces. However, in the laser-etched groups, the bonding strength after 3 weeks was the same as that for the nonbleached group. Conclusions: When teeth bleached with 38% hydrogen peroxide are meant to be bonded immediately, acid etching is preferable.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.20 no.6
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• pp.1773-1783
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• 1996

Finite element method(FEM) is one of the most popularly used method analyzing the dynamic behaviors of structures. But unless number of finite elements is large enough, the results from FEM some what different from exact analytical solutions, especially at high frequency range. On the other hand, as the spectral analysis method(SAM) deals directly with the governing equations of a structure, the results from this melthod cannot but be exact regardless of any frequency range. However, the SAM can be applied only to the case where a structure is subjected to the concentrated loads, despite a structure could be unddergone distributed loads more generally. In this paper, therefore, new spectral analysis algorithm is introduced through the spectral element method(SEM), so that it can be applied to anlystructures whether they are subjected to the concentrated loads or to the distributed loads. The results from this new SEM are compared with both the results from FEM and the exact analytical solutions. As expected, the results from new SEM algorithm are found to be almost identical to the exact analytical solutions while those from FEM are not agreed well with the exact analytical solutions as the mode number increases.