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Two Cases of Papillary Cystic Neoplasm of the Pancreas (췌장의 유두상 낭성암 2예 보고)

  • Choi, Seung-Hoon;Hwang, Eui-Ho
    • Advances in pediatric surgery
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    • v.1 no.1
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    • pp.79-84
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    • 1995
  • Two cases with papillary cystic neoplasm of the pancreas are reviewed and discussed. Up to recently, the tumors have been misclassified as nonfunctioning islet cell tumor or carcinoma, acinar cell carcinoma, papillary cystadenocarcinoma, or pancreatoblastoma. It frequently has been managed with aggressive surgery such as pancreatoduodenectomy. The tumors are well encapsulated and the cut surfaces are characteristically solid and hemorrhagic. Ultrasonography and CT scan are the most useful tools for the diagnosis. The neoplasms usually behave like a very low grade malignancy, so complete removal is the treatment of choice for the tumor arising anywhere in the pancreas. We have a boy and a girl who have papillary cystic neoplasm. The boy was 12 years old and the girl was 14 years old. Both underwent distal pancreatectomy and the progress were uneventful. We have a boy and a girl who have papillary cystic neoplasm. The boy was 12 years old and the girl was 14 years old. Both underwent distal pancreatectomy and the progress were uneventful.

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In vitro Immunomodulating Effects of PALMIWON (팔미원의 in vitro 면역조절 작용)

  • Lee, Ihn-Soon;Rhee, In-Ja
    • YAKHAK HOEJI
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    • v.40 no.6
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    • pp.684-689
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    • 1996
  • PALMIWON is composed of 8 oriental herbs which has been known to show some pharmacological effects in kidney, blood vessels and immune systems, and used for the treatment of kid ney disease, hypertension, nervous disease and diabetic mellitus in the Orient for a long time. Based on our previous report that PALMIWON showed different effects on immune cells and ${\beta}$-cells, the immunoreactivity of ICSA (Islet Cell Surface Antibody) with ${\beta}$-cell (RINm5F) and the cell proliferation and function of interleukin-1${\beta}$ damaged ${\beta}$-cells in the presence of PALMIWON were examined. It was observed that PALMIWON significantly inhibited the immunoreactivity of ICSA with ${\beta}$-cell, and markedly increased cell proliferation and insulin release of interleukin-1${\beta}$ damaged ${\beta}$-cells.

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Pretreatment with SAENGCHINYANGHYOLTANG to prevent the pancreatic enzymes changes by streptozotocin in rats (고혈당(高血糖) 쥐의 췌장(膵臟) 효소활성(酵素活性)에 미치는 생진양혈탕(生津養血湯)의 영향(影響))

  • Kim, Shin-Soek;Choi, Jong-Won;Lee, Cheol-Whan
    • The Journal of Korean Medicine
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    • v.15 no.2 s.28
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    • pp.429-444
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    • 1994
  • The present study was undertaken in order to elucidate the effect of pretreatment with Saengchinyanghyoltang(SYT) on changes in serum glucose level, body weight. water consumption. serum insulin concentration and activities of pancreatic enzymes in rats treated with streptozocin(STZ)-induced diabetic state. Histological studies were also carried out to elevate the effects on pancreatic tissues and Langelhans islet cells. SYT pretreatment in STZ diabetic rats inhibited the rise of fasting serum glucose concentration and water consumption. Pretreatment with SYT significantly increased the concentration of blood insulin and body weight changes compared to the STZ-treated group. Pancreatic lipase and trypsin activities were increased. but amylase activity was decreased and pancreatic ${\beta}-cell$ was destroyed by STZ but. pretreatment with SYT prevented these STZ-induced changes.

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The Effect of Reserpine on the Metabolism of the Alloxan treated Rabbit (Alloxan 투여가토(投與家兎)의 대사(代謝)에 미치는 Reserpine 의 효과(效果))

  • Shin, Kyung-Chul
    • The Korean Journal of Pharmacology
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    • v.5 no.2
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    • pp.81-86
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    • 1969
  • Alloxan is a diabetogenic agent which destroys the beta-cell of the Langerhan's islet of pancreas and it disturbs the secretion of insulin. It is known that alloxan interfers with the hepatic enzyme activity and some aspect of the other metabolism. The author attempted to investigate the influence of reserpine upon the serum transaminase activity, blood sugar and serum total cholesterol contents of rabbit treated alloxan. The results obtained were summarized as follows; 1. The serum GOT and GPT activity of alloxanized rabbit pretreated with reserpine showed marked decrease compared with alloxan control group. 2. The blood sugar level of alloxanized rabbit pretreated with reserpine showed lower than the alloxan control group. 3. The total cholesterol level of alloxanized rabbit pretreated with reserpine was lower than that of alloxan control group.

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Drug-Induced Diabetes Mellitus and Monitoring Hyperglycemic Control in Dogs II. Relationship among Blood Glucose and Serum Fructosamine (개에 있어서 약물에 의한 당뇨병의 유발과 혈당제어의 감시에 관한 연구 II. 당뇨병 모델 개에 있어서 혈당량과 혈청 Fructosamine농도 변화의 시간적 상관관계)

  • 이창우;최회인;김본원
    • Journal of Veterinary Clinics
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    • v.15 no.2
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    • pp.291-302
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    • 1998
  • Four out of 15 dogs were successfully induced diabetes mellitus with intravenous iqiection of 30 mg of streptozotgin and 50 mg of alloxan monohydrate per kilogram body weight and maintained more than 9 weeks without iqiection of insulin or oral hypoglycemic sgent Histopathologicallyi these four dogs have typical diabetic lesions such as degeneration and vacuolation of pancreatic islet cells, and fatty change of liver at necropsy in the end of study. Serum glucose level increased dramatically at 24 hours post-injection but serum fructosamine level increased gradually and reached plateau at 31-41 days post-injection of streptozotocin and alloxan. Serum fructosamine concert%lion correlated very well with serum glucose concentration of preceding 4-7 weeks in experimentally induced diabetic dogs. Our data suggest that serum fructosamine reflects mean glucose concentration of preceding 4-7 weeks in experimentally induced diabetic dogs.

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First record of Odontozona arbur(Decapoda: Stenopodidae: Odontozona) from Korea

  • Lee, Seok Hyun
    • Journal of Species Research
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    • v.9 no.3
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    • pp.247-250
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    • 2020
  • Shrimp of the family Stenopodidae occurr in tropical, subtropical and warm temperate parts of the world. Thirty-seven species of four genera (Juxtastenopus, Odontozona, Richardina, and Stenopus) of the family Stenopodidae have been reported in the world. Among them, only Stenopus hispidus of the family Stenopodidae has been recorded from Korean waters. The stenopodid shrimp, Odontozona arbur is reported for the first time from Korea. During a taxonomic survey of the deacapod crustaceans in Korean waters, O. arbur was collected by scuba diving in approximately 14 m depth from the Munseom Islet, in Jejudo Island on 28 Jun 2018. Odontozona arbur is the second species of the family Stenopodidae in Korea. It is easily distinguished from other species of this family in Korea by the entire dorsal surface of the abdominal somites. The morphology of this species is described and illustrated herein.

Hemocytic Differeatiation in Sericinus montela Grey (Lepidoptera: Papilionidae) (꼬리명주나비(Sericinus montela Grey)의 혈구분화)

  • 권선방;허양훈;양희영
    • The Korean Journal of Zoology
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    • v.38 no.3
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    • pp.313-323
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    • 1995
  • Ultrastructural characteristics of hemocytic differentiation pathway in Sericinus montetla Grey were observed with transmission electron microscope. Hemocytic differentiation took place in loose islets of hemopoietic organs as indicated by the presence of differentiating hemocytes; prohemocytes, plasmatocytes, granular cells and spherule cells. They are differentiatied from the stem cells through individual cell lineages. However, differentiating aspects of the oenocytoids were not observed. According to Brehelin and Zachary (1986), the premature hemocytes around the hemopoietic organs were classified into five types; prohemocytes, plasmatocytes, granular cells, spherule cells and oenocytoids.

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부산광역시 서구 두도.암남공원 자연사 유산의 산출상

  • Kim, Hang-Muk
    • 한국지구과학회:학술대회논문집
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    • 2010.04a
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    • pp.55-57
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    • 2010
  • 부산 서구 두도(Doodo Islet 頭島)공원과 인접 암남(岩南)공원일대는 후기 백악기 (약 8,000만년 전) 유천층군의 다대포층(多大浦層)이 분포되어 있으며 이 층의 쇄설성퇴적암으로부터 공룡알 공룡알둥지 조각류 공룡 배아(embryo)화석 육식공룡과 초식공룡의 싸움터 유적 초식공룡의 피부화석 직경 30mm의 알(공룡?)화석 공룡골화석 새화석 나자식물 둥치화석 양치식물 잎과 목편 인상화석 등 동식물 화석이 대량으로 쏟아져 나왔고(발견자 : 필자와 한석운 공동), 종유석 해식동굴 해식애 해안단구 파식대지 풍화혈 구조 Stacks과 Stumps 해안자갈과 모래 등 지형자연사 유적과 장군산 등 후기 백악기의 화산 자연산 유적이 즐비하여 이곳은 국가적 보물로 평가되고 있다. 아래에 이들 자연사 유산을 기록으로 남길까 한다.

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Insulin Delivery Systems: Current Topic

  • Jeong, Seo-Young
    • Journal of Pharmaceutical Investigation
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    • v.16 no.3
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    • pp.89-100
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    • 1986
  • Although insulin has been available for the treatment of diabetes mellitus for more than half a centry, the deficiency of conventional insulin therapy for diabetic patients have, to this date, not been satisfactorily overcome by any method. The development of potential delivery systems for insulin is highly important to prevent excessive fluctuation of plasma glucose levels, which results in long term complications in the diabetic. There are three major approaches toward development of glucose responding insulin delivery systems: A bioengineering approach is to devise mechanical components capable of releasing insulin in amounts appropriate to varying blood-glucose requirements. A biological approach relies upon cultured, living pancreatic beta cells encapsulated to constitute an insulin delivery unit. A biochemical approach is to synthesize a stable and biologically active glycosylated insulin that is complementary to the binding sites of lectin. This paper will cover several specific areas, including pancreatic transplantation(total or isolated islet cells), artificial pancreases(bioengineering or biological approach), controlled delivery system, glucose sensitive membrane systems, and a self-regulating insulin delivery system.

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Experimental Studies on the Tolerance of Anodonta woodiana against Temperature, Phenol and Lead (수온, 페놀 및 납에 대한 펄조개의 내성 실험)

  • Kim, Jae-Jin
    • The Journal of Natural Sciences
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    • v.11 no.1
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    • pp.85-88
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    • 1999
  • This study was carried out to determine the lethal water temperature and lethal concentrations of phnol and lead on Anodonta woodiana collected from Bam islet in Han river, Seoul, Korea. Lethal temperature$(LT_{48,50})$ on a woodiana was $37-38^{\circ}C$, and lethal concentrations$(LC_{50})$ of phenol and lead nitate were 1200 ppm and 220 ppm, respectively.

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