• 동의신경정신과학회지
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• 제22권4호
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• pp.111-124
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• 2011

Objectives : This case series was conducted to report the efficacy of Ondam-tanggami for insomnia. Methods : Insomnia patients with more than 15 points on Insomnia Severity Index scale were assessed using SCL-90-R, STAI, STAXI, BDI. Being treated with Ondam-tanggami after 2 weeks, ISI, STAI, STAXI, BDI were re-measured to determine the progress of insomnia. It is measured that total sleep time, number of awaking times during sleep, satisfaction of sleep daily. Results : After treatment, quality of sleep has improved and ISI, STAI, STAXI, BDI score have decreased. Conclusions : According to the study, treatment with Ondam-tanggami for insomnia has shown positive results. Further use of Ondam-tanggami is much anticipated for future treatment of insomnia cases.

• 수면정신생리
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• 제24권2호
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• pp.97-105
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• 2017

목 적 : 본 연구의 목적은 불면증과 정신병적 증상이 지속되는 조현병 환자의 수면 장애와 연관된 요인과 수면의 특징을 평가하는 것이다. 방 법 : 지역사회 정신보건 시설에 거주 중이며 불면증과 정신병적 증상이 동반된 조현병 환자들이 참여하였다(n = 63). The Korean version of Insomnia Severity Index (ISIK)와 the Korean Version of Pittsburgh Sleep Quality Index (PSQI-K)와 같은 수면 척도가 평가되었고, ISI-K 점수가 15점 이상인 대상자들이 연구에 참여하였다. 정신병적, 불안, 우울 증상은 각각 Brief Psychotic Rating Scale (BPRS), the Korean Version of Anxiety Sensitivity Index (K-ASI) 그리고 the Korean Version of Beck Depression Inventory-I(K-BDI)로 평가하였다. 사회인구학적 자료와 ISI-K 그리고 PSQI-K 사이의 상관관계를 확인하기 위해 Pearson correlation analysis를 시행하였다. ISI-K와 PSQI-K에 영향을 미치는 각각의 요인을 확인하기 위하여 다중회귀분석으로 분석하였다. 결 과 : ISI-K와 PSQI-K의 평균 점수는 각각 $18.1{\pm}2.6$점과 $12.0{\pm}2.2$점이었다. Pearson correlation analysis 결과에서 발병 연령과 ISI-K사이의 음의 상관관계와 BPRS와 PSQI-K 사이, K-ASI와 모든 수면 척도 사이의 양의 상관관계를 확인하였다. ISI-K와 PSQI-K에 대해 K-ASI와 발병연령, K-ASI와 BPRS를 각각 단계적으로 입력한 모든 다중회귀분석에서 K-ASI만이 유의한 요인으로 남았다. 결 론 : 본 연구는 조현병 환자의 불면 증상이 우울 또는 정신병적 증상과 무관한 반면, 불안 증상과 관련이 있다는 점을 제안한다.

• 동의생리병리학회지
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• 제24권5호
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• pp.892-897
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• 2010

Insomnia is common disease generating about 30% incidence in Korea. It describes not only a state of a lack of sleep but also a causative factor for both psychological and physical disorders. According to Oriental Medicine theory, there are many causes of insomnia, and Wibulhwa(胃不和) is one of causes. In this study, we diagnosed as Wibulhwa(胃不和) for three patients and mainly treated with Modified Yukgunja-tang. We compared with before and after Insomnia Severity Index(ISI) treatment. As a result, ISI score falled, and it showed an improvement in insomnia. So we suggest that Modified Yukgunja-tang might be usefully applied to the treatment of insomnia caused by Wibulhwa(胃不和).

• 동의신경정신과학회지
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• 제23권3호
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• pp.63-76
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• 2012

Objectives : The aim of this study was to investigate the value and efficacy of BDI, STAI, STAXI, ISI, and SCL-90-R in correlation with depression, anxiety, and insomnia patients. Methods : A total of 39 patients, who were diagnosed with depression, anxiety, and insomnia were evaluated using BDI, STAI, STAXI, ISI, and SCL-90-R. They were then statistically analyzed. Results : 1. BDI scores of depression patients were significantly different from other patients. 2. BDI scores of depression patients had strong positive correlation with STAI-S, and STAI-T scores. 3. STAI-S scores of anxiety patients had positive correlation with BDI, and ISI scores. 4. SCL-90-R depression subscale scores of depression patients had strong positive correlation with somatization, obsessive compulsive, interpersonal sensitivity, anxiety, hostility, phobic anxiety, paranoid ideation, psychoticism, global severity index, and positive symptom total subscale scores. 5. SCL-90-R anxiety subscale scores of anxiety patients had strong positive correlation with somatization, obsessive compulsive, depression, phobic anxiety, and global severity index subscale scores. Phobic anxiety subscale scores had strong positive correlation with anxiety, global severity index, and positive symptom total subscale scores. Conclusions : The result findings are expected to serve as a useful resource in future stress-related depression, anxiety, and insomnia case reports and clinical research in oriental neuropsychiatry.

• 대한한방내과학회지
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• 제41권3호
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• pp.494-501
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• 2020

Objectives: Insomnia is a common condition that causes deterioration of cognitive function and physical function and has a negative impact on quality of life. Insomnia is experienced by more than one-third of the population of the world. Although sleeping pills are currently used as therapeutic agents, they have side effects, so safer treatment methods are needed. Therefore, we report a case of an outpatient who sleeps only one hour a day due to insomnia. Methods: The patient visited Korean Medicine Hospital 10 times for four weeks and was treated with Korean medicine therapies, including electroacupuncture on the back-Shu points and herbal medicine (Yukmijihwang-tang and Hwangnyeonhaedok-tang). Treatment progress was assessed using the Pittsburgh Sleep Quality Index (PSQI) and the Insomnia Severity Index (ISI). Results: After 29 days of treatment, the PSQI score decreased from 20 points and 14 points. The ISI score also decreased to decreased to 22 points from 26 points. The average daily sleeping time increased from 60 minutes to 197.1 minutes after treatment. No significant side effects were observed. Conclusions: Yukmijihwang-tang and Hwangnyeonhaedok-tang with electroacupuncture might be a recommended therapeutic option for insomnia patients.

• 대한한의학회지
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• 제36권1호
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• pp.86-92
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• 2015

불면을 동반한 건선(乾癬) 환자(患者)에게 불면과 건선(乾癬)의 경중이 비례하는 양상을 보인 환자(患者)에게 불면을 치료(治療)하면 건선(乾癬)이 회복될 것으로 판단되었다. 이와 관련하여 심혈부족(心血不足)이 불면의 원인(原因)이라고 판단되는 건선(乾癬) 환자(患者)에게 귀비탕(歸脾湯)을 투약해서 불면과 건선(乾癬)이 동시에 회복되는 결과(結果)를 확인했다. 아직 명확한 건선(乾癬) 치료(治療) 지침이 확립되지 않은 상황에서 건선(乾癬) 자체를 보고 접근해야 하는 경우도 있지만 건선(乾癬)과 동반된 기저 질환이 건선(乾癬)의 경중과 비례한다면 동반된 질환을 치료(治療)해서 건선(乾癬)을 치료(治療)할 수 있다는 가능성을 얻었다. 앞으로 건선(乾癬) 환자(患者)가 다른 기저 질환을 동반하고 이러한 질환의 경중이 건선(乾癬)과 비례한다면 이 질환의 치료(治療)를 시도하는 것이 건선(乾癬)의 회복에 도움을 줄 수 있을 것으로 보인다.

• 한국보건간호학회지
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• 제32권2호
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• pp.263-274
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• 2018

Purpose: This study examined the correlation of insomnia, sleep quality, depression, and circadian rhythm in nursing students. Methods: A total of 213 subjects completed a questionnaire consisting of their general characteristics, Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), Center for Epidemiologic Studies Depression (CES-D), and Composite Scale of Morningness (CSM). The collected data were analyzed by descriptive statistics, t-test, ANOVA, and Pearson's correlation coefficient using the SPSS 23.0 program. Results: The subjects' mean scores were ISI 7.18; PSQI 11.18; CES-D 16.00; and CSM 30.18. In insomnia, there were significant differences according to caffeine, perceived health status and major satisfaction. In sleep quality, there were significant differences according to perceived health status and major satisfaction. Significant differences in depression were observed according to gender, caffeine, subjective health status, major satisfaction, and circadian rhythm by drinking and exercise. A significant positive correlation was observed among ISI, PSQI, and CES-D. ISI and CES-D were negatively correlated. Conclusion: Tailored health care programs should be developed and applied to prevent and manage sleep-related and emotion-related problems in nursing students by considering the health status, major satisfaction, and gender.

• 대한한방내과학회지
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• 제43권2호
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• pp.212-218
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• 2022

Objective: This study reports the effects of Gyejigeojakyakgachokchilmolyeoyonggol-tang (GCMYT) in a patient with insomnia after COVID-19 vaccination. Methods: GCMYT was used to treat insomnia following vaccination, and symptoms were evaluated using the Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), and a visual analog scale (VAS). Results: The patient's PSQI, ISI, and VAS scores decreased from 21 to 11, from 25 to 13, and from 7 to 3, respectively. Conclusion: GCMYT is an effective treatment for insomnia following COVID-19 vaccination.

• 정신신체의학
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• 제27권1호
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• pp.50-59
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• 2019

연구목적 2형 당뇨병을 지닌 환자의 다수에서 수면문제가 동반되며, 이들에서 불면증의 비율은 일반 인구에 비해서 높다고 알려져 있다. 본 연구의 목적은 2형 당뇨병 환자에서 불면증의 발생빈도, 불면증의 임상적 특징 및 이에 연관되는 변인을 알아보기 위함이다. 방 법 2형 당뇨병으로 진단받은 18세에서 80세 이하의 99명(남자 65명, 여자 34명)을 대상으로 연구자 1인(제1저자)가 면담을 시행하였다. 면담으로 수면 잠복기, 총 수면시간을 조사하였고, 한국판 불면증 심각도 지수(Korean Version of Insomnia Severity Index, ISI-K) 평가하고, 우울증상의 심각도는 한국판 Hamilton 우울증 평가 척도(Korean Version of the Hamilton Depression Rating Scale, K-HDRS)로 평가하였다. ISI-K의 절취점 15.5점을 기준으로 불면증 있는 군(N=34명)과 불면증 없는 군(N=65)으로 양분하여 불면증군과 대조군의 여러 변인과의 연관성을 상관분석하고 다중 로지스틱 회귀분석을 사용하여 검토하여 다음의 결과를 얻었다. 결 과 2형 당뇨병 환자의 34.34%(N=34)에서 불면증이 있었다. 불면증이 있는 2형 당뇨병 환자군은 불면증이 없는 2형 당뇨병 환자군보다 유의하게 미혼(11.8%)이나 이혼(11.8%)이많았고(p<0.05), K-HDRS 총점($11.76{\pm}5.52$점)이 높았으며(p<0.001), 총수면시간($5.35{\pm}2.00$시간)이 짧았고(p<0.001), 수면잠복기($50.29{\pm}33.80$분)가 길었다(p<0.001). 불면증이 있는 2형 당뇨병 환자군은 불면증이 없는 2형 당뇨병 환자군보다 ISI-K 검사상 합계($18.38{\pm}2.69$점), A1 (입면)($2.97{\pm}0.76$점), A2 (수면유지)($3.06{\pm}0.69$점), A3 (일찍 깸)($2.76{\pm}0.61$점), B (수면만족도)($3.18{\pm}0.72$점), C (수면장애로 인한 기능방해)($2.09{\pm}0.97$점), D (남이 알아차림)($2.12{\pm}1.09$점), E (수면장애에 대한 걱정)($2.21{\pm}0.81$점) 등 모든 항목의 점수가 유의하게 높았다(각각 p<0.001). 2형 당뇨병 환자에서 불면증에 영향을 미치는 요인들은 다음과 같다. 나이는 ISI-K A3 항목과 유의한 역상관관계가 있었고 (${\beta}=-0.241$, p<0.05), K-HDRS 총점은 ISI-K 모든 항목과 유의한 순상관관계가 있었으며(각각 p<0.05), 총 수면시간은 ISI-K 모든 항목과 유의한 역상관관계가 있었다(각각 p<0.05). 수면잠복기는 ISI-K 합계, A1, B, E 항목과 유의한 순상관관계가 있었다(각각 p<0.05). 결 론 2형 당뇨병 환자의 약 1/3에서 불면증이 존재하며, 불면증이 없는 2형 당뇨병 환자군과 수면의 양적 및 질적 차이가 있음을 시사한다. 우울증상의 심각도는 2형 당뇨병 환자의 불면증과 상관관계가 있으므로 우울증의 조기 발견과 치료가 요구된다.

• 동의신경정신과학회지
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• 제24권1호
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• pp.103-108
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• 2013

Objectives : Korea's average life expectancy is getting longer and longer and the pace of change in society has increased every year as people experience stress more easily. Under this situation, chronic sleep disorder is increasing, but there is no specific program for the treatment of sleep disorder in Korean medicine. Therefore, we studied a Korean medical treatment program for sleep disorder to apply to outpatient clinic patients. Methods : For this study, we evaluated the Insomnia Severity Index (ISI), BDI, STAI, FSS on 29 insomnia patients who visited Kyunghee Korean medical hospital from July 2010 to May 2012. Herbal medicine, acupuncture, herbal acupuncture, moxibustion, sleep hygiene, and medical qigong were applied. We compared ISI scores before treatment and after 4 weeks of treatment. Results : ISI score was improved after Korean medical treatment for sleep disorder. Before the treatment ISI score was 18.1, which means clinical insomnia. After the Korean medical treatment, the score was 7.5, which means no clinically significant insomnia. Conclusions : The study showed a significant effect on the Korean medical treatment program for sleep disorder to apply to outpatient clinic patients. ISI score was improved and the patients were satisfied with the treatment, so it would be more helpful to apply in sleep clinics.