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Short Tenn Reactions to Acupuncture Treatment and Adverse Events Following Acupuncture in Korea a Cross-sectional Survey of Patient Reports (침치료 직 후 자가 설문지를 이용한 침반응(針感)과 부작용에 대한 단면적 연구)

  • Park, Seong-Uk;Jung, Woo-Sang;Moon, Sang-Kwan;Ko, Chang-Nam;Cho, Ki-Ho;Kim, Young-Suk;Bae, Hyung-Sup;Park, Jung-Mi
    • The Journal of Korean Medicine
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    • v.28 no.2 s.70
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    • pp.66-79
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    • 2007
  • Objectives : To explore the type and frequency of short term reactions, de Qi associated with acupuncture treatment and to determine the incidence of adverse events following acupuncture in Korea. Subjects and methods : This study is a retrospective and cross-sectional survey of patient reports. 1095 subjects, 585 of out-patients of the Oriental Medicine of Stroke & Neurological Disorders Center, East-West NEO Medical Center of Kyunghee University and 510 of out-patients of the Department of Cardiovascular & Neurologic Diseases (Stoke Center), Hospital of Oriental Medicine, Kyunghee Medical Center, from June through November of 2006, who had acupuncture, gave informed consent and completed one survey form. On this form, patients were asked to report short term acupuncture reactions, de Qi, patient satisfaction measurement (using VAS), and adverse events relating to acupuncture treatment. The acupuncturists of this study are Korean Medicine Doctors (KMD) who had worked as practitioners for 3-30 years or more. Results : The average age of the 1095 subjects was 58 years old. Positive short term acupuncture reactions after treatment were reported by 878 (80.2%), negative short term acupuncture reactions by 75 (6.8%) and no reactions were reported by 142 (13.0%). The most common positive short term acupuncture reactions were feeling 'relaxed', 472 (43.1%), followed by feeling 'less pain' 90 (8.2%), 'energized' 16 ( 1.5%), 'tingling' 16 (1.5%), 'heat feeling or Cold feeling' 10 (0.9%), and others 274 (25.0%), respectively. Negative short term acupuncture reactions were feeling 'pain' 37 (3.4%), tiredness 24 (2.2%), dizziness 9 (0.8%), and others 5 (0.2%), respectively. Traditionally described needling sensations of de Qi refer to a patient's response to distention, pulling, soreness, heaviness, numbness. 39.7% of subjects reported de Qi during needling, experiencing 'distention' 333 (30.4%), 'soreness' 52 (4.7%), 'pulling' 22 (2.0%), 'heaviness' 18 (1.6%), and 'numbness' 10 (0.9%) respectively. Positive short term acupuncture reactions and de Qi rate were the highest in the less than 40 years group (83/96 86.5%, 50/96 52.1%). No acupuncture reactions were highly seen in the over 70 years old group (31/187, 16.6%). Patient satisfaction level using VAS was a comparatively high $72.9{\pm}19.9$. Adverse events were only bleeding in 92 (8.4%) of the total subjects. High sensitive acupoints were 95 points as GV26 (54 times), LI4 (54 times), ST36 (53 times), GB20 (37 times), HT8(34 times), LV3 (29 times), SI3 (29 times), and LI11 (27 times) in order. Main impressions were stroke patients 430 (16.9%), headache 185 (16.9%), hypertension 97 (8.9%), and dizziness 85 (7.8%). Conclusions : Although 8 different Korean Medicine Doctors participated in this research, we obtained similar results from each. There were no significantly different results between the two hospitals. Short term acupuncture reactions and de Qi were most related to age. Except for bleeding there were no adverse events relating to acupuncture treatment in this study. We consider acupuncture treatment as very safe depending on practitioners. Positive short term acupuncture reactions after treatment were 12 times higher than negative short term acupuncture reactions. Subjects were comparatively satisfied with acupuncture treatment.

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A Clinical Study of the Acute Respiratory Distress Syndrome in Children (소아에서의 급성 호흡 곤란 증후군에 대한 임상적 고찰)

  • Lee, Taek Jin;Kim, Dong Soo;Shin, Dong Hwan
    • Clinical and Experimental Pediatrics
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    • v.46 no.1
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    • pp.42-50
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    • 2003
  • Purpose : The acute respiratory distress syndrome(ARDS), an acute form of severe alveolar-capillary injury evolving after a direct or indirect lung insult is thought to be a common cause of respiratory failure though not many clinical studies on the subject have been made yet. Methods : Between January 1992 and December 2001, we conducted a retrospective study on 33 children who fulfilled the definition of the ARDS recommended by the American-European Consensus Conference in 1994. Results : A total of 33 patients(20 boys and 13 girls) were selected. Their age ranged from 4 months to 12 years with seven children younger than 1 year. The overall mortality rate was 78.8% and no significant difference was noted based on age or sex. Concerning seasonal variation, incidence of the ARDS increased in spring, especially in May(21.2%). Pneumonia(66.7%) was found to be the most common risk factor of the ARDS followed by sepsis(24.2%) and aspiration(3.0%). In immune compromised children(six cases), including a recipient of bone marrow transplantation, the mortality rate was 100%. Compared with children with multiple organ failure recording a 83.3% mortality rate, those with isolated respiratory failure, showed a lower mortality rate of 33.3%, although stastistically insignificant. Between survivor and non-survivor groups, significant differences were shown in hematocrit, $PaO_2$, $PaCO_2$, PEEP, and $PaO_2/FiO_2$ on the seventh day after the onset of the ARDS. Conclusion : According to our study, respiratory failure proved to have a great effect on mortality rate in the ARDS. More aggressive intervention and further studies on this subject should be done to improve the survival rate.

Comparative analysis on status of events and importance-performance analysis (IPA) between industry and school foodservices (사업체급식소와 학교급식소의 이벤트 실태 및 이벤트에 대한 중요도-수행도 분석 비교)

  • Song, Hyun Jin;Rho, Jeong Ok
    • Journal of Nutrition and Health
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    • v.47 no.6
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    • pp.452-462
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    • 2014
  • Purpose: The purpose of the study was to evaluate the status of events and importance-performance analysis (IPA) between industry and school foodservices. Methods: The study subjects were dietitians in industry foodservices (n = 73) and nutrition teachers in school foodservices (n = 135) in the Jeonbuk area. Demographic characteristics, status of events, and problems of implementing events were assessed using a self-administered questionnaire. Results: Approximately 67% of industry foodservices had implemented an event a month, whereas 40.7% of school foodservices did not implement events for students. The type of events that industry and school foodservices had implemented most frequently were Sambok event, Dongji event, Daeboreum event, Spring-Namul event, and Chuseok event. The industry foodservices had significantly higher average scores for performance of events than those of the school foodservices (p < 0.001). In the Importance-Performance Analysis (IPA), high importance and high performance (A area: doing great) in industry foodservices were seasonal events, traditional festival day events, anniversary events, traditional seasonal events, and personal memory events, whereas in school foodservices were traditional festival day events, traditional seasonal events, school events, and environment events. Conclusion: These results showed that events are important for the increase in customer satisfaction. Therefore, it is necessary to consider educational programs on event implementation for dietitians and employees in industry and school foodservices.

Hypoglycemic Effect of Culture Broth of Bacillus subtilis S10 Producing 1-Deoxynojirimycin (1-Deoxynojirimycin을 생산하는 Bacillus subtilis S10 배양액의 혈당강하 효과)

  • Cho, Yong-Seok;Park, Young-Shik;Lee, Jae-Yeon;Kang, Kyung-Don;Hwang, Kyo-Yeol;Seong, Su-Il
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.11
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    • pp.1401-1407
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    • 2008
  • 1-Deoxynojirimycin (DNJ) is a strong $\alpha$-glucosidase inhibitor which inhibits hyperglycemia in animals. To select the Bacillus strains highly producing DNJ, 4,000 strains were isolated from soil and grain samples. By the inhibitory activity against $\alpha$-glucosidase, nine Bacillus strains were selected and then identified by 16S rDNA sequencing. B. subtilis S10 was finally selected as the best strain for the production of DNJ. Various carbon sources and nitrogen sources in culture medium were evaluated for the highest production of DNJ. As the results, the optimized concentration of carbon source and nitrogen source was 1.0% galactose and 1.6% polypeptone and the concentration of DNJ produced was 0.75 g/L. The effect of culture supernatant of B. subtilis S10 on lowering blood glucose level was investigated in streptozotocin (STZ)-induced diabetic mice model. Mice were randomly assigned to control group (saline) and three test groups such as acarbose group, silkworm powder group and B. subtilis S10 group. After eight-week oral feeding, blood glucose levels of the B. subtilis S10 and silkworm powder groups were respectively $209.1{\pm}19.6\;mg/dL$ (59.1%) and $208.6{\pm}39.8\;mg/dL$ (59.0%) lower than $510{\pm}10\;mg/dL$ of the control group. These results indicated that the culture supernatant of B. subtilis S10 was able to reduce the blood glucose level in STZ-induced diabetic mice.

Effect of Microbial Phytase on Performance, Nutrient Absorption and Excretion in Weaned Pigs and Apparent Ileal Nutrient Digestibility in Growing Pigs

  • Zeng, Z.K.;Piao, X.S.;Wang, D.;Li, P.F.;Xue, L.F.;Salmon, Lorraine;Zhang, H.Y.;Han, X.;Liu, L.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.8
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    • pp.1164-1172
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    • 2011
  • Two experiments were conducted to evaluate the efficacy of Trichoderma reesei derived phytase for pigs fed diets with fixed calcium to total phosphorus ratios (1.5:1). In Exp. 1, 280 weaned pigs (initial BW of $10.32{\pm}1.94$ kg) were allocated to one of five dietary treatments on the basis of weight and gender in a randomized complete block design. Treatments were the low phosphorus (0.6% Ca, 0.4% total P and 0.23% available P) diets supplemented with 0, 250, 1,000, or 2,000 FTU phytase/kg of diet and a positive control diet (PC; 0.85% Ca, 0.58% total P and 0.37% available P). The treatments were applied to seven pens with eight pigs per pen, half male and half female. In Exp. 2, six barrows fitted with ileal T-cannula (initial BW = $35.1{\pm}1.6$ kg) were assigned to three dietary treatments with a double $3{\times}3$ Latin square design. The dietary treatments were the low-phosphorus diet (0.53% Ca, 0.34% total P and 0.14% available P), the low phosphorus diet plus 1,000 FTU phytase/kg and a positive control diet (0.77% Ca, 0.50% total P and 0.30% available P). In Exp. 1, there were linear increases (p<0.01) in weight gain, phosphorus absorption, bone strength, calcium and phosphorus content of fat-free dried bone and plasma phosphorus concentrations with increasing dose rate of phytase. The performance of pigs fed the diets with 250, 1,000, or 2,000 FTU of phytase/kg did not differ from pigs fed the PC diet. Pigs fed diets with 1,000 or 2,000 FTU of phytase/kg did not differ from pigs fed the PC diet in bone characteristics. The apparent digestibility of dry matter, crude protein, ash and energy was not affected by dietary treatment. However, pigs fed the PC diet excreted more fecal phosphorus (g/d, p<0.01) and fecal phosphorus per BW gain (g/kg) than pigs fed the diets with phytase. Phytase linearly decreased (p<0.01) fecal phosphorus excreted per BW gain (g/kg), plasma calcium concentration as well as plasma and bone alkaline phosphatase activity. In Exp. 2, phytase supplementation in the low-P diet increased (p<0.05) the apparent ileal digestibility (AID) of Ca, P, leucine, lysine, phenylalanine, alanine and cysteine, tended to AID of crude protein, isoleucine, threonine, asparagine and serine. In conclusion, the novel phytase originated from Trichoderma reesei is effective in releasing Ca, P, and amino acids from corn soy based diet for pigs.

THE EFFECT OF WASHING PHOSPHORIC ACID ETCHANT ON SHEAR BOND STRENGTH OF AN ORTHODONTIC ADHESIVE (인산 부식액의 수세가 교정용 접착레진의 전단결합강도에 미치는 영향)

  • Kim, Hee-Kyun;Lee, Ki-Soo;Park, Young-Guk
    • The korean journal of orthodontics
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    • v.26 no.5 s.58
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    • pp.497-507
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    • 1996
  • The aim of present study in vitro was to evaluate and compare the effects of different washing times of enamels etched with low phosphoric acid solution which makes unsoluble salts and etched but contaminated with saliva on shear bond strength of an orthodontic adhesive to enamel, and to observe the washing effect on the etched enamel surface by scanning electron microscope. All brackets were bonded with Mono-$Lok2^{TM)}$) on the labial surface of extracted human bicuspids after etching with $20w/w\%\;and\;37w/w$ and phosphoric acid solution for 60seconds and then washing for 0,5,10 and 20seconds respectedly. After etching with $37w/w\%$ phosphoric acid solution and contaminating with saliva for 30seconds and then washing for 0,5,20 and 30seconds and re-etching for 10seconds. After 24hours passed in the $37^{\circ}C$ water bath, the shear bond strengths were measured on Universal Test Machine. The data were evaluated and tested by ANOVA and Duncan's multiple range test, and those results were as follows. 1. There was no significant differences between (p>0.05) shear bond strength of bonded brackets with 5, 10, 20seconds washing etched enamel using $37{\%}w/w{\%}$ phosphoric acid solution. 2. The shear bond strength of bonded brackets with $20w/w\%$ phosphoric acid and then washing for 5seconds showed bonded strength durable to occlusal force but its coefficiency score was high and etched surface was not cleaned completely and therefore it was assumed that its clinical application is not applicable. 3. There was no significant differences between (p>0.05) shear bond strengths of bonded brckets with washing for 5seconds etched enamel using $37w/w\%$ phosphoric acid solution and 10,20 seconds washing etched enamel using $20w/w\%$ phosphoric acid solution. 4. The shear bond strength of washing for 5seconds etched enamel which was contaminated with saliva showed sufficient bonded strength durable to occlusal force but its coefficiency score was high and therefore its clinical application was not applicable. 5. After etching, the sample contaminated with saliva showed the sufficient shear bond strength even washing 20seconds without re-etching.

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A Statistical Analysis on Nursing-Related These in Korea (우리나라 간호학 및 간호학 관련 학위논문 분석)

  • Kim, Hui-Geol;Lee, Yeong-Suk
    • The Korean Nurse
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    • v.34 no.5
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    • pp.68-81
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    • 1996
  • In order to see the development of nursing related research activities in Korea over the last three decades, abstracts of almost all of the Masters and Ph. D. theses that had appeared from 1961 up to August 1991 were collected. Number of theses amounted to 1779(76%) out of a total of 2354 theses. We analysed the papers research patterns, which are research problem, research design, population, place. Here is what we have found. 1). The types of research problems were as follows. 58.0% papers did factor-analysis, 29.1% studied factor~relations, 11.4% situation relations and 1.5% did situation~creations. With respect to the years, we found that the factor-analysis papers decreased with time but the factor~relating, the situation -relating, and the situation~creating papers were increased. Especially the situation-creating paper increased notably since the 80s'. Relating to the kind of degrees, we found that for M.S.theses 60.2% of the papers did factor-analysis, 29.0% the factor-relating studies, 10.4% the situation-relating studies, and 0.4% the situation -creating studies. For the Ph.D. theses 30.5% did the factor~relating, 30.5% the situation-relating. and 20.0% the situation-creating papers. Considering the graduate schools, we found that the regular graduate schools and the graduate school of education produced about the same number of papers of each kind, but 81.2% and 64.6% papers produced by the graduate school of public health and the graduate school of public administration, respectively, did the factor-analysis thus taking majority of the papers. 2). Research designs were as follows : 10.8% experimental studies, 89.0% non experimental studies, and 0.2% quality studies were found. So the majority of the research designs were nonexperimental. We see a meaningful difference between the M.S.theses showing 9.8% experimental studies and 90. 1% nonexperimental studies. and Ph.D. theses showing 28.4% experimental studies and 68. 4% nonexperimental studies. Relating to the graduate schools, we find that the regular graduate schools and the graduate school of education with 15.8% and 10.6% experimental studies respectively, did a little more experimental studies than other schools. but still the regular graduate schools, the graduate school of public health, and the graduate school of education each show 83.8%, 97.4%, and 89.4% nonexperimental studies, so most schools are concentrating on nonexperimental studies. 3). On the relation between research problem and research design, experimental studies show 88.0% of situation-relations and 6.8% of factor-relations. Nonexperimental studies had factor-analysis taking the majority by 64.4% and 31.9% were factor-relations. 4). On the research subjects, we have 90.8% of the papers dealing with a single subject and 9.2% of the papers dealing with two or more subjects. Most of the research subjects are patients or nurses for the regular graduate schools and the graduate school of education, but for the graduate school of administration as much as. 60% of the studies took nurses as subjects. Subjects taken were patients, nurses. and students in decreasing order for the M.S. theses and for patients, women, and nurses again in decreasing order for the Ph.D.theses. 5). On the places of study, we've had 47, 8% of the studies done in hospital rooms, 15, 1% in schools, and 9, 6% in the local community, With respect to the years, we found 36.7% in the hospital rooms, 22.4% in the schools, and 14, 8% in the local communities in the 1970's and 50.1%in the hospital rooms, 13.4% in the schools. and 9, 2% in the local communities in the 80's.

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Carbon Reduction Effects of Urban Landscape Trees and Development of Quantitative Models - For Five Native Species - (도시 조경수의 탄소저감 효과와 계량모델 개발 - 5개 향토수종을 대상으로 -)

  • Jo, Hyun-Kil;Kim, Jin-Young;Park, Hye-Mi
    • Journal of the Korean Institute of Landscape Architecture
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    • v.42 no.5
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    • pp.13-21
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    • 2014
  • This study generated regression models to quantify storage and annual uptake of carbon from five native landscape tree species through a direct harvesting method, and established essential information to estimate carbon reduction effects from urban greenspaces. Tree species for the study included the Chionanthus retusus, Prunus armeniaca, Abies holophylla, Cornus officinalis, and Taxus cuspidata, which are usually planted in cities of middle Korea, but for which no information on carbon reduction is available. Ten tree individuals for each species were sampled reflecting various stem diameter sizes at a given interval. The study measured biomass for each part including the roots of sample trees to compute total carbon storage per tree. The annual carbon uptake per tree was quantified by analyzing the radial growth rates of stem samples at breast height or ground level. Regression models were developed using diameter at breast height (dbh) or ground level (dg) as an independent variable to easily estimate storage and annual uptake of carbon per tree for each species. All the regression models showed high fitness with $r^2$ values of 0.92~0.99. Storage and annual uptake of carbon from a tree with dbh of 10 cm were greatest with C. retusus (20.0 kg and 5.9 kg/yr, respectively), followed by P. armeniaca (17.5 kg and 4.5 kg/yr) and A. holophylla (13.2kg and 1.8 kg/yr) in order. A C. officinalis tree and T. cuspidata tree with dg of 10 cm stored 9.3 and 6.3 kg of carbon and annually sequestered 3.2 and 0.6 kg, respectively. The above-mentioned carbon storage equaled the amount of carbon emitted from gasoline consumption of about 23~35 L for C. retusus, P. armeniaca, and A. holophylla, and 11~16 L for C. officinalis and T. cuspidata. A tree with the diameter size of 10 cm annually offset carbon emissions from gasoline use of about 6~10 L for C. retusus, P. armeniaca, and C. officinalis, and 1~3 L for A. holophylla and T. cuspidata. The study breaks new ground to easily quantify biomass and carbon reduction for the tree species by overcoming difficulties in direct cutting and root digging of urban landscape trees.

Development of Automated Region of Interest for the Evaluation of Renal Scintigraphy : Study on the Inter-operator Variability (신장 핵의학 영상의 정량적 분석을 위한 관심영역 자동설정 기능 개발 및 사용자별 분석결과의 변화도 감소효과 분석)

  • 이형구;송주영;서태석;최보영;신경섭
    • Progress in Medical Physics
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    • v.12 no.1
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    • pp.41-50
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    • 2001
  • The quantification analysis of renal scintigraphy is strongly affected by the location, shape and size of region of interest(ROI). When ROIs are drawn manually, these ROIs are not reproducible due to the operators' subjective point of view, and may lead to inconsistent results even if the same data were analyzed. In this study, the effect of the ROI variation on the analysis of renal scintigraphy when the ROIs are drawn manually was investigated, and in order to obtain more consistent results, methods for automated ROI definition were developed and the results from the application of the developed methods were analyzed. Relative renal function, glomerular filtration rate and mean transit time were selected as clinical parameters for the analysis of the effect of ROI and the analysis tools were designed with the programming language of IDL5.2. To obtain renal scintigraphy, $^{99m}$Tc-DTPA was injected to the 11 adults of normal condition and to study the inter-operator variability, 9 researchers executed the analyses. The calculation of threshold using the gradient value of pixels and border tracing technique were used to define renal ROI and then the background ROI and aorta ROI were defined automatically considering anatomical information and pixel value. The automatic methods to define renal ROI were classified to 4 groups according to the exclusion of operator's subjectiveness. These automatic methods reduced the inter-operator variability remarkably in comparison with manual method and proved the effective tool to obtain reasonable and consistent results in analyzing the renal scintigraphy quantitatively.

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Implicit Distinction of the Race Underlying the Perception of Faces by Event-Related fMRI (Event-related 기능적 MRI 영상을 통한 얼굴인식과정에서 수반되는 무의식적인 인종구별)

  • Kim Jeong-Seok;Kim Bum-Soo;Jeun Sin-Soo;Jung So-Lyung;Choe Bo-Young
    • Investigative Magnetic Resonance Imaging
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    • v.9 no.1
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    • pp.43-49
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    • 2005
  • A few studies have shown that the function of fusiform face area is selectively involved in the perception of faces including a race difference. We investigated the neural substrates of the face-selective region called fusiform face area in the ventral occipital-temporal cortex and same-race memory superiority in the fusiform face area by the event-related fMRI. In our fMRI study, subjects (Oriental-Korean) performed the implicit distinction of the race while they consciously made familiar-judgments, regardless of whether they considered a face as Oriental-Korean or European-American. For race distinction as an implicit task, the fusiform face areas (FFA) and the right parahippocampal gyrus had a greater response to the presentation of Oriental-Korean faces than for the European-American faces, but in the conscious race distinction between Oriental-Korean and European-American faces, there was no significant difference observed in the FFA. These results suggest that different activation in the fusiform regions and right parahippocampal gyrus resulting from superiority of same-race memory could have implicitly taken place by the physiological processes of face recognition.

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