• Proceedings of the Korean Society for Bioinformatics Conference
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• 2005.09a
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• pp.431-436
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• 2005

Living cells are sustained not by individual activities but rather by coordinated summative efforts of different biological functional modules. While recent research works have focused largely on finding individual functional modules, this paper attempts to explore the connections or relationships between different cellular functions through cross-function domain interaction maps. Exploring such a domain interaction map can help understand the underlying inter-function communication mechanisms. To construct a cross-function domain interaction map from existing genome-wide protein-protein interaction datasets, we propose a two-step procedure. First, we infer conserved domain-domain interactions from genome-wide protein-protein interactions of yeast, worm and fly. We then build a cross-function domain interaction map that shows the connections of different functions through various conserved domain interactions. The domain interaction maps reveal that conserved domain-domain interactions can be found in most detected cross-functional relationships and a f9w domains play pivotal roles in these relationships. Another important discovery in the paper is that conserved domains correspond to highly connected protein hubs that connect different functional modules together.

• Journal of the Korean Society of Safety
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• v.19 no.2
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• pp.119-124
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• 2004

The effect of soil-structure interaction becomes important in the design of civil structures such as long-span bridges, which are constructed in the site composed of soft soil. Many methodologies have been developed to account for the proper consideration of soil-structure interaction effect. However, it is difficult to estimate soil-structure interaction effect accurately becaused of many uncertainties. This paper presents the results of study on soil-structure interaction and dynamic response of a long-span bridge designed in the site composed of soft soil. The effect of the soft soil was evaluated by the use of computer program SASSI and a long-span bridge structure was modeled by finite elements. Dynamic response characteristics of a long-span bridge considering soil-structure interaction wereinvestigated.

• Journal of Families and Better Life
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• v.26 no.5
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• pp.299-314
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• 2008

The purpose of this study wasto understand Theraplay interaction and to find out how Theraplay works to bring about change in withdrawn children. In exploring the meaning of Theraplay interaction, I used a phenomenology, which looked reflectively into a child's experience. Examining the situation, I found that the child had changed by "touch" with a therapist, which had been done throughout thewhole process of therapy. The child had changed from "child with horny body" to "playful child." Furthermore, I realized the four meanings (of what?) through research: "encounter", "reconstruction", "responsibility", and "immersion." Those four meaningscould have made the subject of interaction go beyond and look for its own existence. In addition, those four meanings melt together in the phenomena of interaction. There were always those four meanings throughout Theraplay interaction. This study has presented different consequences, compared to Theraplay research that is based on effectiveness, and examined the process of change that includes position tendency.

• Proceedings of the KSR Conference
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• 2007.05a
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• pp.1460-1465
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• 2007

CWR(Continuous Welded Rail) and bridge interaction produce rail force, bridge displacement and rail/bridge relative displacement. Each of these has limitation by many codes. In this paper, analysis of interaction has been carried out by using foreign codes(UIC 774-3 R code of Europe etc.) because there is no code about interaction between rail and bridge in Korea. Recently, railway bridges with CWR has been constructed for structural and economical reasons. When designer plans railway bridges, design a bridge model first and then investigate railway forces and displacement by interaction analysis. If these results go out bounds from limitation, designer plans railway bridges again and again. In this paper, using the parametric study on CWR and railway bridge interaction, railway bridge parameters such as length of bridge span, area of bridge, moment of inertia, stiffness of pier, etc. are presented. It helps preliminary design of railway bridges.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2007.04a
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• pp.445-450
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• 2007

CWR(Continuous Welded Rail) and bridge interaction produce rail force, bridge displacement and rail/bridge relative displacement. Each of these has limitation by many codes. In this paper, analysis of interaction has been carried out by using foreign codes(UIC 774-3 R code of Europe etc.) because there is no code about interaction between rail and bridge in Korea. Recently, railway bridges with CWR has been constructed for structural and economical reasons. When designer plans railway bridges, design a bridge model first and then investigate railway forces and displacement by interaction analysis. If these results go out bounds from limitation, designer plans railway bridges again and again. In this paper, using the parametric study on CWR and railway bridge interaction, railway bridge parameters such as length of bridge span, area of bridge, moment of inertia, stiffness of pier, etc. are presented. It helps preliminary design of railway bridges.

• 유체기계공업학회:학술대회논문집
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• 2000.12a
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• pp.219-225
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• 2000

Primary function of a centrifugal compressor volute is to serve the flow from the impeller and diffuser to pipe system. But losses in volutes at off-design lead to poor stage efficiency and reduction of operating range. This is largely caused by the interaction between the impeller and volute flow fields. The magnitude of distortion is increased as the operating point is away from the design point and, as a result, the interaction between the impeller and volute is stronger. The objective of present study is to find the characteristics of tile flow in the diffuser and volute of the centrifugal compressor with rectangular cross-sectional volute. The measurements are carried out in two cases with the existence and nonexistence of the volute casing. The detailed pressure is presented by comparing the experimental results obtained at two cases with each others.

• 한국전산유체공학회:학술대회논문집
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• 2008.03a
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• pp.337-339
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• 2008

As a shock impinges into a vortex of variable strength, complex shock diffraction can occur. Since a vortex has a fixed rotating direction, the shock wave travelling in one direction creates strong asymmetry in the vortex flow field. The process is that first the shock is divided into two parts by the vortex. One part is moving in the adverse direction opposite to the vortex flow which is captured by the vortex center. The other part is moving in the favorable direction, namely, in the direction same as the vortex flow; it is swung around the vortex, accelerating the vortex flow. In this paper we have investigated numerically using ENO scheme how and why the shock-vortex interaction patterns appear so different for different parametric values. Conclusion is that there are three different types of shock-vortex interaction depending on two related parameters: shock Mach number and vortex Mach number. We present a parameter map by which we can discern what type of interaction pattern appears as a shock impinges into a vortex.

• 한국전산유체공학회:학술대회논문집
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• 2008.10a
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• pp.337-339
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• 2008

Abstract: As a shock impinges into a vortex of variable strength, complex shock diffraction can occur. Since a vortex has a fixed rotating direction, the shock wave travelling in one direction creates strong asymmetry in the vortex flow field. The process is that first the shock is divided into two parts by the vortex. One part is moving in the adverse direction opposite to the vortex flow which is captured by the vortex center. The other part is moving in the favorable direction, namely, in the direction same as the vortex flow; it is swung around the vortex, accelerating the vortex flow. In this paper we have investigated numerically using ENO scheme how and why the shock-vortex interaction patterns appear so different for different parametric values. Conclusion is that there are three different types of shock-vortex interaction depending on two related parameters: shock Mach number and vortex Mach number. We present a parameter map by which we can discern what type of interaction pattern appears as a shock impinges into a vortex.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.20 no.1
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• pp.377-383
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• 1996

Interaction of flames in a lean-rich concentration field is studied numerically adopting a counterflow as a model problem. Detailed kinetic mechanism is adopted in analyzing the structure of various type of flames which can be found in lean-rich interaction. Flow field is simplified to quasi one-dimensional by using boundary layer approximation and similarity formulation. Triple flames are identified and its structure shows that a diffusion flame is located in the middle of two premixed flames. Such a diffusion flame is formed by $H_2$ and CO generated from the rich premixed flame and $O_2$ leaked from the lean premixed flame. The flame position can be identified either from the hydrogen production rate or the heat release rate. Transition from single diffusion flame to triple flame is observed as degree of premixing is increased.

• Structural Engineering and Mechanics
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• v.45 no.3
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• pp.311-321
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• 2013

In this study, to have a better judgment on the structural performance, the effects of dynamic Soil-Structure Interaction (SSI) on seismic behaviour and lateral structural response of mid-rise moment resisting building frames are studied using Finite Difference Method. Three types of mid-rise structures, including 5, 10, and 15 storey buildings are selected in conjunction with three soil types with the shear wave velocities less than 600m/s, representing soil classes $C_e$, $D_e$ and $E_e$, according to Australian Standard AS 1170.4. The above mentioned frames have been analysed under two different boundary conditions: (i) fixed-base (no soil-structure interaction), and (ii) flexible-base (considering soil-structure interaction). The results of the analyses in terms of structural lateral displacements and drifts for the above mentioned boundary conditions have been compared and discussed. It is concluded that the dynamic soil-structure interaction plays a considerable role in seismic behaviour of mid-rise building frames including substantial increase in the lateral deflections and inter-storey drifts and changing the performance level of the structures from life safe to near collapse or total collapse. Thus, considering soil-structure interaction effects in the seismic design of mid-rise moment resisting building frames, particularly when resting on soft soil deposit, is essential.