• 제목/요약/키워드: IRS

검색결과 308건 처리시간 0.028초

The Spitzer First Look survey Verification Field : Deep Radio and multi-wavelength properties

  • 김기훈;김성은;;김한성;김연화
    • 천문학회보
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    • 제37권2호
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    • pp.74.1-74.1
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    • 2012
  • We observed the radio sources found from the First Look Survey (FLS) field at the 1.4 GHz radio continuum emission with the Very Large Array (VLA) using the A configuration. We identify point sources and multi component sources at ${\geq}4{\sigma}$ level. We also present the submillimeter properties of the selected radio sources in the FLS field from the Herschel/SPIRE 250/350/500/${\mu}m$ and AzTEC 1.1mm surveys. The counterparts of the radio sources at submillimeter for these called 'submillimeter galaxies (SMGs)' are detected at infrared wavelength with the Spitzer MIPS 24 & 70 ${\mu}m$ sources. Based on the MMT/HECTOSPEC red-shift survey, IRS spectroscopy, and SDSS photometric red-shift survey, the radio sources are likely to be the extragalactic sources. Here, we use the star formation rate (SFR) derived from the MIPS 24 and 70 ${\mu}m$ luminosity to compare the measured SFR from the VLA 1.4 GHz luminosity. These results show that a tight correlation between the SFR from the radio luminosity and the MIPS $24{\mu}m$ rather than that from the MIPS $70{\mu}m$ luminosity. Radio and IR correlation is also used to indicate the radio and IR properties of star-formation in the galaxies and active galactic nuclei (AGNs). Using the counterpart sources selected at IR and radio wavelengths, we employ the IR/radio flux ratios to determine the properties and population of the selected galaxies.

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Effect of Ethyl Pyruvate on Paclitaxel-Induced Neuropathic Pain in Rats

  • Choi, Seong Soo;Koh, Won Uk;Nam, Jae Sik;Shin, Jin Woo;Leem, Jeong Gill;Suh, Jeong Hun
    • The Korean Journal of Pain
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    • 제26권2호
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    • pp.135-141
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    • 2013
  • Background: Although paclitaxel is a widely used chemotherapeutic agent for the treatment of solid cancers, side effects such as neuropathic pain lead to poor compliance and discontinuation of the therapy. Ethyl pyruvate (EP) is known to have analgesic effects in several pain models and may inhibit apoptosis. The present study was designed to investigate the analgesic effects of EP on mechanical allodynia and apoptosis in dorsal root ganglion (DRG) cells after paclitaxel administration. Methods: Rats were randomly divided into 3 groups: 1) a control group, which received only vehicle; 2) a paclitaxel group, which received paclitaxel; and 3) an EP group, which received EP after paclitaxel administration. Mechanical allodynia was tested before and at 7 and 14 days after final paclitaxel administration. Fourteen days after paclitaxel treatment, DRG apoptosis was determined by activated caspase-3 immunoreactivity (IR). Results: Post-treatment with EP did not significantly affect paclitaxel-induced allodynia, although it tended to slightly reduce sensitivities to mechanical stimuli after paclitaxel administration. After paclitaxel administration, an increase in caspase-3 IR in DRG cells was observed, which was co-localized with NF200-positive myelinated neurons. Post-treatment with EP decreased the paclitaxel-induced caspase-3 IR. Paclitaxel administration or post-treatment with EP did not alter the glial fibrillary acidic protein IRs in DRG cells. Conclusions: Inhibition of apoptosis in DRG neurons by EP may not be critical in paclitaxel-induced mechanical allodynia.

Efficient Utilisation of Credit by the Farmer - Borrowers in Chittoor District of Andhra Pradesh, India - Data Envelopment Analysis Approach

  • Kumar, K. Nirmal Ravi
    • Agribusiness and Information Management
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    • 제8권2호
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    • pp.1-8
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    • 2016
  • The present study has aimed at analyzing the technical and scale efficiencies of credit utilization by the farmer-borrowers in Chittoor district of Andhra Pradesh, India. DEA approach was followed to analyze the credit utilization efficiency and to analyze the factors influencing the credit utilization efficiency, log-linear regression analysis was attempted. DEA analysis revealed that, the number of farmers operating at CRS are more in number in marginal farms (40%) followed by other (35%) and small (17.5%) farms. Regarding the number of farmers operating at VRS, small farmers dominate the scenario with 72.5 per cent followed by other (67.5%) and marginal (42.5%) farmers. With reference to scale efficiency, marginal farmers are in majority (52.5%) followed by other (47.5%) and small (25%) farmers. At the pooled level, 26.7 per cent of the farmers are being operated at CRS, 63 per cent at VRS and 32.5 per cent of the farmers are either performed at the optimum scale or were close to the optimum scale (farms having scale efficiency values equal to or more than 0.90). Nearly 58, 15 and 28 percents of the farmers in the marginal farms category were found operating in the region of increasing, decreasing and constant returns respectively. Compared to marginal farmers category, there are less number of farmers operating at CRS both in small farmers category (15%) and other farmers category (22.5%). At the pooled level, only 5 per cent of the farmers are operating at DRS, majority of the farmers (73%) are operating at IRS and only 22 per cent of the farmers are operating at CRS indicating efficient utilization of credit. The log-linear regression model fitted to analyze the major determinants of credit utilization (technical) efficiency of farmer-borrowers revealed that, the three variables viz., cost of cultivation and family expenditure (both negatively influencing at 1% significant level) and family income (positively influencing at 1% significant level) are the major determinants of credit utilization efficiency across all the selected farmers categories and at pooled level. The analysis further indicate that, escalation in the cost of cultivation of crop enterprises in the region, rise in family expenditure and prior indebtedness of the farmers are showing adverse influence on the credit utilization efficiency of the farmer-borrowers.

A case study of red tide detection around Korean waters using satellite remote sensing

  • Suh, Y.S.;Lee, N.K.;Jang, L.H.;Kim, H.G.;Hwang, J.D.
    • 대한원격탐사학회:학술대회논문집
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    • 대한원격탐사학회 2003년도 Proceedings of ACRS 2003 ISRS
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    • pp.654-655
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    • 2003
  • Korea has experienced 10 a Cochlodinium polykrikoides red tide outbreaks during the last 10 years (1993-2002). The monitoring activities at National Fisheries Research and Development Institute (NFRDI) in Korea have been extended to all the coastal waters after the worst of fish killing by C. polykrikoides blooms in 1995. NFRDI is looking forward to finding out the feasibility of red tide detection around Korean waters using satellite remote sensing of NOAA/AVHRR, Orbview-2/SeaWiFS, IRS-P4/OCM and Terra/MODIS on real time base. In this study, we used several alternative methods including climatological analysis, spectral and optical methods which may offer a potential detection of the major species of red tide in Korean waters. The relationship between the distribution of SST and C. polykrikoides bloom areas was studied. In climatological analysis, NOAA, SeaWiFS, OCM satellite data in 20th and 26th August 2001 were chosen using the known C. polykrikoides red tide bloom area mapped by helicopter reconnaissance and ground observation. The 26th August, 2001 SeaWiFS chlorophyll a anomaly imageries against the imageries of non-occurring red tide for August 20, 2001 showed the areas C. polykrikoides occurred. The anomalies of chlorophyll a concentration from satellite data between before and after red tide outbreaks showed the similar distribution of C. polykrikoides red tide in 26th August, 2001. The distribution of the difference in SST between daytime and nighttime also showed the possibility of red tide detection. We used corrected vegetation index (CVI) to detect floating vegetation and submerged vegetation containing algal blooms. The simple result of optical absorption from C. polykrikoides showed that if we use the optical characteristics of each red tide we will be able to get the feasibility of the red tide detection.

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악성 횡문근 육종의 방사선 치료 (Treatment Results of Rhabdomyosarcoma)

  • 이연구;안기정;서창옥;김귀언;노준규;안희정;최인준;김병수
    • Radiation Oncology Journal
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    • 제7권2호
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    • pp.235-245
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    • 1989
  • Rhabdomyosarcoma is a highly malignant soft tissue sarcoma that can arise in any site of the body containing striated muscle or its mesenchymal analgae. It is the most common childhood sarcoma with two peak age frequencies, one at ages 2 to 6, and one in the adolescence. The site, stage and extent of disease, and pathologic characteristics of the tumor contribute to prognostic factors that influence therapeutic decisions. The results of treatment of 52 patients with rhabdomyosarcoma, who were treated at Department of Radiation Oncology, Yonsei University College of Medicine, Yosei Cancer Center from 1976 to 1987 were retrospectively analyzed. The most frequent clinical group and primary sites were IRS group III (57.7%) and head and neck (42.3%) including orbit (11.5%) and parameningeal region(13.5%). The overall and disease free 5 year survival rate of eligible 41 patients were 31.7%, 29.3%, respectively. The complete remission (CR) rate was 50% in clinical group III and 0% in IV. Primary tumors of the orbit, clinical group 1 and embryonal subtype had the best prognosis. The Survival rate was improved by additiion of chemotherapy to operation and radiation therapy.

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Validation and selection of GCPs obtained from ERS SAR and the SRTM DEM: Application to SPOT DEM Construction

  • Jung, Hyung-Sup;Hong, Sang-Hoon;Won, Joong-Sun
    • 대한원격탐사학회지
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    • 제24권5호
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    • pp.483-496
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    • 2008
  • Qualified ground control points (GCPs) are required to construct a digital elevation model (DEM) from a pushbroom stereo pair. An inverse geolocation algorithm for extracting GCPs from ERS SAR data and the SRTM DEM was recently developed. However, not all GCPs established by this method are accurate enough for direct application to the geometric correction of pushbroom images such as SPOT, IRS, etc, and thus a method for selecting and removing inaccurate points from the sets of GCPs is needed. In this study, we propose a method for evaluating GCP accuracy and winnowing sets of GCPs through orientation modeling of pushbroom image and validate performance of this method using SPOT stereo pair of Daejon City. It has been found that the statistical distribution of GCP positional errors is approximately Gaussian without bias, and that the residual errors estimated by orientation modeling have a linear relationship with the positional errors. Inaccurate GCPs have large positional errors and can be iteratively eliminated by thresholding the residual errors. Forty-one GCPs were initially extracted for the test, with mean the positional error values of 25.6m, 2.5m and -6.1m in the X-, Y- and Z-directions, respectively, and standard deviations of 62.4m, 37.6m and 15.0m. Twenty-one GCPs were eliminated by the proposed method, resulting in the standard deviations of the positional errors of the 20 final GCPs being reduced to 13.9m, 8.5m and 7.5m in the X-, Y- and Z-directions, respectively. Orientation modeling of the SPOT stereo pair was performed using the 20 GCPs, and the model was checked against 15 map-based points. The root mean square errors (RMSEs) of the model were 10.4m, 7.1m and 12.1m in X-, Y- and Z-directions, respectively. A SPOT DEM with a 20m ground resolution was successfully constructed using a automatic matching procedure.

황칠, 닥나무, 꾸지뽕 혼합 추출물의 항당뇨 효과 (Antidiabetic Effects of Mixed Extract from Dendropanax morbiferus, Broussonetia kazinoki, and Cudrania tricuspidata)

  • 김솔;김상준;오준석;홍재희;김선영
    • 대한한의학방제학회지
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    • 제27권3호
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    • pp.223-236
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    • 2019
  • Dengropanax morfiferus (D), Broussonitia kazinoki (B), and Cudriania tricuspidata (E), a widely cultivated species in South Korea, has been used as traditional medicine to treat numerous diseases. In this study, we evaluated the antidiabetic effects in a various signaling mechanisms using mixed extract and major component contents were analyzed by HPLC in the combined extracts from Dengropanax morfiferus, Broussonitia kazinoki, and Cudriania tricuspidata (DBCE). DBCE inhibited ${\alpha}$-glucosidase and ${\alpha}$-amylase activation and showed potent antioxidant effects, which are evaluated using DPPH, ABTS, and SOD assay. Cytokines, which are released by inflammatory cells in pancreatic islets, are involved in the pathogenesis of type 1 diabetes mellitus. DBCE showed the protective effects in RINm5F cells against cytokines-induced damage by suppressing inducible nitric oxide (NO) synthase and COX-2 expression and NO production. Insulin resistance is the primary characteristic of type 2 diabetes. Therefore, the regulatory effect of DBCE on glucose uptake and production are investigated in insulin-responsive human HepG2 cells. DBCE stimulated glucose uptake, prevented Glut2 and phosphor-IRS1 downregulation induced by high glucose (HG, 30 mM). Moreover, DBCE pretreatment diminished glucose levels, PEPCK and G6Pase overexpression provoked by HG. These findings suggest that DBCE might be used for diabetes treatment through alpha-glucosidase or alpha-amylase activity regulation, pancreatic beta cell protection, hepatic glucose sensitivity improvement. Cytokines, which are released by inflammatory cells' infiltrations around the pancreatic islets, are involved in the pathogenesis of type 1 diabetes mellitus.

고성장 전기·전자사업의 경영효율성 (Management Efficiency of High-growth Electrical and Electronics Industry)

  • 강다연;이기세
    • 한국콘텐츠학회논문지
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    • 제19권8호
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    • pp.151-158
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    • 2019
  • 국내 전기 전자 산업이 보유하고 있는 높은 기술력은 국외 시장에서도 인정받고 있지만 현재 주변국과의 기술경쟁 등이 갈수록 심화되어져 가고 있는 상황이다. 따라서 이들 기업들이 경쟁우위를 차지하기 위해서는 무엇보다 운영상의 비효율성을 재정비하여 효율적인 생산 활동을 실시하여야한다. 이에 본 논문에서는 DEA 기업을 통해 국내 고성장 전기 전자사업의 경영효율성을 분석하며 비효율적인 기업의 투사값을 제시하며 벤치마킹의 대상이 될 수 있는 기업들의 참조집합을 확인하고자 한다. 이를 위해 총 20개 고성장 전기 전자기업들의 CCR와 BCC모형의 효율성과 규모수익성(RTS)을 분석하였다. 분석결과 BCC 효율성이 1인 기업은 총 12개, CCR 효율성이 1인 기업은 총 4개 기업으로 나타났다. 그리고 BCC, CCR 효율성이 모두 1인 기업은 총 4개 기업이었다. 또한 기업의 규모수익성은 IRS가 11개 기업, CRS가 6개 기업 그리고 DRS가 3개 기업으로 분석되었으며 참조빈도 분석에서는 BCC모형에서는 4개 기업과 CCR 모형을 통해 4개 기업을 벤치마킹이 할 수 있는 기업으로 제시하였다. 이러한 결과는 동종 산업의 후발 기업들에게 기업의 운영환경을 개선할 수 있는 유용한 정보가 될 것이다.

WCPFC 수역 원양연승어업의 눈다랑어 생산함수 추정 (Estimation of Bigeye tuna Production Function of Distant Longline Fisheries in WCPFC waters)

  • 조헌주;김도훈;김두남;이성일;이미경
    • 자원ㆍ환경경제연구
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    • 제28권3호
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    • pp.415-435
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    • 2019
  • 본 연구의 목적은 중서부태평양(WCPFC) 수역 우리나라 원양연승어업의 눈다랑어 생산함수를 추정하여 규모 수익을 분석하는 것이다. 분석에 있어 투입요소는 선원수, 선박톤수, 투입낚시수, 눈다랑어 자원량 그리고 산출요소는 눈다랑어 생산량으로 하는 Cobb-Douglas 형태의 생산함수를 추정하였다. 함수 추정에 앞서 투입요소 중 눈다랑어 자원량은 Bayesian State-space 모델로 추정하였다. 생산함수 추정 결과, 하우즈만 검정을 통해 고정효과 모델이 선택되었고, 선원수를 제외한 선박톤수, 투입낚시수, 눈다랑어 자원량이 눈다랑어 생산량에 직접적인 영향을 미치는 것으로 나타났다. 추정된 생산함수의 투입요소를 바탕으로 규모 수익 수준을 분석한 결과, WCPFC 수역에서 눈다랑어를 조업하는 원양연승어업은 규모 수익 체증(IRS)의 성격인 것으로 추정되었다.

고과당식이 랫드모델에서 적하수오 투여에 의한 대사증후군 개선효과 (Beneficial effect of Polygoni Multiflori Radix in high fructose diet-induced metabolic syndrome rat model)

  • 고민철;이윤정;윤정주;이호섭;강대길
    • 대한본초학회지
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    • 제30권2호
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    • pp.11-18
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    • 2015
  • Objectives : Polygoni Multiflori Radix (Jeokhasuo in Korean) is a Oriental traditional herbs widely used in East Asian countries. Overconsumption of fructose results in hypertension, dyslipidemia, obesity and impaired glucose tolerance which have documented as a risk of cardiovascular diseases. This experimental study was designed to investigate the beneficial effects of an ethanol extract from Polygoni Multiflori Radix (PMR) in high-fructose (HF) diet-induced metabolic syndrome rat model. Methods : Sprague-Dawley (SD) rats were divided into three groups; Control group, receiving regular diet and tap water, HF group, and HF + PMR group both receiving supplemented with 65% fructose (n=10), respectively. The HF + PMR group initially received HF diet with PMR (100 mg/kg/day) for 8 weeks. Results : PMR significantly prevented the metabolic disturbances such as hyperlipidemia, hypertension and impaired glucose tolerance. Chronic treatment with PMR significantly decreased body weight, fat weight and adipocyte size, suggesting a role of anti-obesity effect. PMR led to improve the hyperlipidemia through the increase in HDL cholesterol level as well as the decrease in triglyceride and LDL cholesterol level. In addition, PMR suppressed adhesion molecules and endothelin-1 (ET-1) expression in aorta resulting in the decrease of hypertension. In muscle tissue, PMR significantly recovered the HF-induced insulin resistance through increase of insulin receptor substrate-1 (IRS-1), p-$AMPK{\alpha}1/2$, and p-Akt expression. PMR improved HF-induced metabolic disorders and its action was caused by energy metabolism-mediated insulin signaling activation. Conclusions : These results demonstrate that PMR may be a beneficial therapeutic for metabolic syndrome through the improvement of hyperlipidemia, obesity, insulin resistance and hypertension.