• 한국작물학회지
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• 제34권3호
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• pp.280-287
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• 1989

분얼하는 옥수수 교잡종인 IK//IRI/B68과 분얼을 하지 않는 일대 교잡종 옥수수인 진주옥을 공시하여 이들 사이의 작물생장 과정을 비교·검토한 결과를 요약하면 다음과 같다. 1. 분얼형 옥수수인 IK//IRI/B68의 초장 및 생체중은 생육초기에는 진주옥보다 낮았으나 생육후기에서는 더 높게 나타났다. 2. 분얼형 옥수수 IK//IRI/B68의 개체당 평균 분얼수는 3.7개였으며, 주간과 분얼간의 생장은 비슷한 크기를 보였다. 3. 분얼형 옥수수인 IK//IRI/B68의 건물중은 생육초기에는 진주옥보다 낮았으나 생육후기에는 분얼의 증가에 따른 경엽의 증가로 높게 나타났다. 4. 분얼형 옥수수인 IK//IRI/B68의 LAI는 분얼 발생 이후부터 진주옥보다 높게 나타났는데 최고분 시기 이후인 춘현후 80일경에는 이들에 대한 LAI값이 각각 12.6과 5.8이었다. 5. 분얼형 옥수수인 IK//IRI/B68의 CGR은 진주옥보다 출현후 60일경까지는 낮았으나 분얼간이 신장 발달함에 따라 더 높게 나타났다. 6. 분얼형 옥수수인 IK//IRI/B68의 LAR 및 RGR은 진주옥보다 생육초기에는 더 높게 나타났는데, IK//IRI/B68의 RGR은 NAR과 LAR의 영향을 받는 반면에 진주옥의 RGR은 LAR에 의한 영향을 받는 것으로 나타났다.

• 건축역사연구
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• 제21권6호
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• pp.63-76
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• 2012

Modern railway construction by Japanese had a great influence on the urbanization, transformation of urban structure and landscape during the Japanese imperialism and compressive increasing period in Iri(Iksan). This paper aims to find out the effect of railway on the modern urban structure and urban landscape in Iri(Iksan). Railways in Iri, Honam railway, Kunsan railway, Jeonla railway have been constructed progressively during 1911 and 1915 with Iri and old Iri(east-Iri) station. From the analysis of land registration maps and street plans, old photographies and historical records, some significant features underling railway construction can be followed in view of modern urbanization process in Iri. Firstly railways cut off the possibility of developing urban structure based on traditional spatial structure of Iksan. Secondly railways made dual spatial structure in Iri. Japanese and Korean life zone were divided into separate district around urbanization area and market place. Thirdly traditional space cognition system based on four cardinal directions were changed to front and rear space of railway station. Fourthly railways and stations caused neo-baroque spatial order and imperialistic urban landscape of Iri with axis, vista and gridiron plan. Fifthly break points and fringe belts garbling modern urbanization process are created. Sixthly modern cultural and consumptive urban spaces were taken their seats in relation with daily urban life.

• Journal of Chest Surgery
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• 제54권1호
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• pp.9-16
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• 2021

Background: The deposition of monomeric C-reactive protein (mCRP) in the myocardium aggravates ischemia-reperfusion injury (IRI) and myocardial infarction. Ischemic preconditioning (IPC) is known to protect the myocardium against IRI. Methods: We evaluated the effects of IPC on myocardium upon which mCRP had been deposited due to IRI in a rat model. Myocardial IRI was induced via ligation of the coronary artery. Direct IPC was applied prior to IRI using multiple short direct occlusions of the coronary artery. CRP was infused intravenously after IRI. The study included sham (n=3), IRI-only (n=5), IRI+CRP (n=9), and IPC+IRI+CRP (n=6) groups. The infarcted area and the area at risk were assessed using Evans blue and 2,3,5-triphenyltetrazolium staining. Additionally, mCRP immunostaining and interleukin-6 (IL-6) mRNA reverse transcription-polymerase chain reaction were performed. Results: In the IRI+CRP group, the infarcted area and the area of mCRP deposition were greater, and the level of IL-6 mRNA expression was higher, than in the IRI-only group. However, in the IPC+IRI+CRP group relative to the IRI+CRP group, the relative areas of infarction (20% vs. 34%, respectively; p=0.079) and mCRP myocardial deposition (21% vs. 44%, respectively; p=0.026) were lower and IL-6 mRNA expression was higher (fold change: 407 vs. 326, respectively; p=0.376), although the difference in IL-6 mRNA expression was not statistically significant. Conclusion: IPC was associated with significantly decreased deposition of mCRP and with increased expression of IL-6 in myocardium damaged by IRI. The net cardioprotective effect of decreased mCRP deposition and increased IL-6 levels should be clarified in a further study.

• Biomolecules & Therapeutics
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• 제25권3호
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• pp.272-278
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• 2017

Fucoidan has been reported to exhibit various beneficial activities ranging from to antivirus and anticancer properties. However, little information is available about the effects of fucoidan on cerebral ischemia-reperfusion injury (IRI). Our study aimed to explore the effects of fucoidan on cerebral IRI, as well as the underlying mechanisms. Sprague-Dawley (SD) rats were randomly subjected to four groups: Sham, IRI+saline (IRI+S), IRI+80 mg/kg fucoidan (IRI+F80), and IRI+160 mg/kg fucoidan (IRI+F160). Fucoidan (80 mg/kg or 160 mg/kg) was intraperitoneally injected from 7 days before the rats were induced to cerebral IRI model with middle cerebral artery occlusion (MCAO) method. At 24 h after reperfusion, neurological deficits and the total infarct volume were determined. The levels of inflammation-associated cytokines (interleukin (IL)-$1{\beta}$, IL-6, myeloperoxidase (MPO), and tumor necrosis factor (TNF)-${\alpha}$), oxidative stress-related proteins (malondialdehyde (MDA) and superoxide dismutase (SOD)) in the ischemic brain were measured by enzyme-linked immunosorbent assay (ELISA). Besides, the levels of apoptosis-related proteins (p-53, Bax, and B-cell lymphoma (Bcl)-2) and mitogen-activated protein kinase (MAPK) pathway (phosphorylation-extracellular signal-regulated kinase (p-ERK), p-c-Jun N-terminal kinase (JNK), and p-p38) were measured. Results showed that administration of fucoidan significantly reduced the neurological deficits and infarct volume compared to the IRI+S group in a dose-dependent manner. Also, fucoidan statistically decreased the levels of inflammation-associated cytokines, and oxidative stress-related proteins, inhibited apoptosis, and suppressed the MAPK pathway. So, Fucoidan plays a protective role in cerebral IRI might be by inhibition of MAPK pathway.

• 국제학술발표논문집
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• The 5th International Conference on Construction Engineering and Project Management
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• pp.507-508
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• 2013

International Roughness Index (IRI) has been widely used by state DOTs to quantify pavement smoothness. When pavement condition falls below certain IRI thresholds, corresponding pavement maintenance treatments should be considered for application. Selection of appropriate IRI thresholds is essential to tactical allocation of limited resources to improve the conditions of states' roadway systems. This selection process is often challenging, however, because IRI thresholds are largely determined by Perceived Ride Quality (PRQ), and PRQ differs in each state. In this paper, a framework is proposed to address this problem. Passenger raters will be randomly selected from predetermined geographic locations, and their PRQ ratings collected. Taking this perceived ride data, along with other data collected, a statistical analysis will be conducted to establish the relationship between measured IRI values and PRQ. Appropriate IRI thresholds will then be determined. Once this framework is implemented, state DOTs could make informative maintenance decisions, which are expected to greatly enhance the public perception of pavement conditions in today's challenging economy.

• 한국도로학회논문집
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• 제19권6호
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• pp.83-95
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• 2017

PURPOSES : The purpose of this study is to develop a regression model to predict the International Roughness Index(IRI) and Surface Distress(SD) for the estimation of HPCI using Expressway Pavement Management System(PMS). METHODS : To develop an HPCI prediction model, prediction models of IRI and SD were developed in advance. The independent variables considered in the models were pavement age, Annual Average Daily Traffic Volume(AADT), the amount of deicing salt used, the severity of Alkali Silica Reaction(ASR), average temperature, annual temperature difference, number of days of precipitation, number of days of snowfall, number of days below zero temperature, and so on. RESULTS : The present IRI, age, AADT, annual temperature differential, number of days of precipitation and ASR severity were chosen as independent variables for the IRI prediction model. In addition, the present IRI, present SD, amount of deicing chemical used, and annual temperature differential were chosen as independent variables for the SD prediction model. CONCLUSIONS : The models for predicting IRI and SD were developed. The predicted HPCI can be calculated from the HPCI equation using the predicted IRI and SD.

• 대한수의사회지
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• 제30권11호
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• pp.679-688
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• 1994

In order to monitor the parasites, fecal samples were taken from chicken (n=1,000), turkey(n=157), helmeted guineafowl(n=149), pheasant(n=190) and duck(n=190) in Chonbuk area. The identification of the parasites were determined by the fecal examination us

• 한국도로학회논문집
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• 제12권1호
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• pp.55-59
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• 2010

높은 차량운행비용(VOC : Vehicle Operating Cost)은 포장도로 복구작업의 주요한 원인이고, 차량운행비용(VOC)은 연료소모량, 오일소모량, 부품교체비용 등으로 구성된다. 이중 연료소모량이 VOC에서 차지하는 비중이 높고, 다른 도로조건에 비해 도로 표면 거칠기가 도로의 노화 정도를 대표적으로 지시하는 값이기 때문에, 본 연구에서는 포장도로의 표면 거칠기(IRI : International Roughness Index) 변화에 따른 차량의 연료소모량 변화를 측정하였다. 차량의 연료분사 인젝터의 전압변화를 측정하여 연료소모량을 계산하였고, 속도는 GPS센서를 사용하여 측정하였다. 본 실험 결과를 이용하여 IRI 변화에 대한 연료소모량의 변화율을 계산할 수 있었다. 계산 결과, 40~100km/h 속도영역에서 중형 및 대형 승용차의 연료소모량(L/100km)은 3.5m/km 정도의 IRI 수준에서 IRI(m/lm) 증가율의 7배 정도로 증가하였고, 60km/h의 속도에서 가장 연비가 우수하였다.

• The Korean Journal of Physiology and Pharmacology
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• 제25권5호
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• pp.413-423
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• 2021

Apoptosis is proved responsible for renal damage during ischemia/reperfusion. The regulation for renal apoptosis induced by ischemia/reperfusion injury (IRI) has still been unclearly characterized to date. In the present study, we investigated the regulation of histone acetylation on IRI-induced renal apoptosis and the molecular mechanisms in rats with the application of curcumin possessing a variety of biological activities involving inhibition of apoptosis. Sprague-Dawley rats were randomized into four experimental groups (SHAM, IRI, curcumin, SP600125). Results showed that curcumin significantly decreased renal apoptosis and caspase-3/-9 expression and enhanced renal function in IRI rats. Treatment with curcumin in IRI rats also led to the decrease in expression of p300/cyclic AMP response element-binding protein (CBP) and activity of histone acetyltransferases (HATs). Reduced histone H3 lysine 9 (H3K9) acetylation was found near the promoter region of caspase-3/-9 after curcumin treatment. In a similar way, SP600125, an inhibitor of c-Jun N-terminal kinase (JNK), also attenuated renal apoptosis and enhanced renal function in IRI rats. In addition, SP600125 suppressed the binding level of p300/CBP and H3K9 acetylation near the promoter region of caspase-3/-9, and curcumin could inhibit JNK phosphorylation like SP600125. These results indicate that curcumin could attenuate renal IRI via JNK/p300/CBP-mediated anti-apoptosis signaling.

• Smart Structures and Systems
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• 제19권2호
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• pp.151-161
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• 2017

A new method is developed to estimate road profile in order to estimate IRI based on the ASTM standard. This method utilizes an accelerometer and a Dynamic Tire Pressure Sensor (DTPS) to estimate road roughness. The accelerometer measures the vertical axle acceleration. The DTPS, which is mounted on the tire's valve stem, measures dynamic pressure inside the tire while driving. Calibrated transfer functions are used to estimate road profile using the signals from the two sensors. A field test was conducted on roads with different quality conditions in the city of Brockton, MA. The IRI values estimated with this new method match the actual road conditions measured with Pavement Condition Index (PCI) based on the ASTM standard, images taken from an onboard camera and passengers' perceptions. IRI has negative correlation with PCI in general since they have overlapping features. Compared to the current method of IRI measurement, the advantage of this method is that a) the cost is reduced; b) more space is saved; c) more time is saved; and d) mounting the two sensors are universally compatible to most cars and vans. Therefore, this method has the potential to provide continuous and global monitoring the health of roadways.