• Title/Summary/Keyword: IRB

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Fluoride concentration in the finger nails of dental hygiene and nonhealth-relate some female students (치위생과와 비보건학과 일부 여대생의 손톱 내 불소농도 차이)

  • Oh, Na-Rae;Park, Eui Jung;Yoon, Sung-Uk
    • Journal of Korean society of Dental Hygiene
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    • v.16 no.1
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    • pp.147-153
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    • 2016
  • Objectives: The purpose of the study is to investigate the relationship between fluorine concentration within finger nails and the level of dentifrice in dental hygiene students and non-health majoring students. Methods: A self-reported questionnaire was completed by seventy female college students living in Daegu and Gyeongbuk that are not supplied with fluoridation from May to June, 2014. Informed consent was approved by institutional review board (IRB). The questionnaire consisted of general characteristics of the subjects (11 items) and oral health behavior including number of toothbrushing, duration of toothbrushing, number of mouth rinsing, and amount of dentifrice. A dentist and a dental hygienist examined directly the subjects by the guideline of World Health Organization (WHO). The oral examination included decayed tooth, healthy tooth, and filled tooth. The nail samples were obtained from seventy female students. Results: Comparing the dental hygiene students and non-health majoring students, 62.5% of dental hygiene students used approximately 1300mg of dentifrice and 55.2% of non-health majoring students used 1800mg or more of dentifrice. The non-health majoring students used more dentifrice (p<0.01). The fluorine concentration within nails was $1.9905{\mu}l/g$ in dental hygiene students and $3.2149{\mu}l/g$ in non-health majoring students. The fluorine concentration within nails in the dental hygiene students was significantly lower(p<0.01). Conclusions: The accumulation of fluoride in human body is not fully caused by dentifrice. However, The accumulation may occur due to toothbrushing so that it is necessary to educate the students about the right use of the dentifrice.

Association of visceral fat obesity and other lifestyle factors with prostate cancer (비만으로 인한 전립선암 발생의 영향연구 : 복부비만도 측정과 그 외 생활 요인)

  • Kim, Myeong-Seong
    • Korean Journal of Digital Imaging in Medicine
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    • v.17 no.1
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    • pp.19-31
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    • 2015
  • 최근 우리나라의 암 발생률은 꾸준히 증가추세에 있고 그 중에서도 전립선암은 갑상선암을 제외했을 때 남성에서 가장 높은 증가 추세를 보이고 있는 암이다. 전립선암은 그 동안 선진국에서 주로 발병하는 것으로 알려진 암 종이지만 서구화된 식습관과 생활 행태 변화로 인하여 국내에서도 발생률이 증가하는 것으로 추정하고 있다. 따라서 국내 환경에 맞는 내장 지방 분포와 같은 정확한 비만도 측정을 통해 우리나라에서 증가율 1위를 보이고 있는 전립선암 발생의 원인 관계를 찾고자 한다. 본 연구는 환자와 정상군 비교를 하는 환자-대조군 연구이고 본 연구를 위하여 임상시험 윤리위원회 (IRB) 승인을 받았다 (NCC2014-0124). 환자군은 2014년 8월 1일부터 2015년 1월 6일 까지 국립암센터를 방문하여 전립선암을 진단받고 수술과 항암치료 그리고 방사선 치료를 시작하지 않은 초진을 대상으로 하였고, 정상군은 2009년 11월부터 2014년 9월 30일까지 공단검진을 목적으로 국립암센터를 방문한 정상인을 대상으로 하였다. 전립선암 연구는 환자 총 52명에 평균 66세 (51 - 82세)이고 정상군은 총 50명에 평균 64세 (59 - 75세) 이다. 모든 연구 대상자들의 생활 요인 평가를 위하여 암 가족력, 흡연, 음주 상태, 운동, 등을 추가적으로 설문 조사하였다. MRI 영상의 배꼽 주위에서의 내장 지방과 피하지방을 전용 분석 컴퓨터를 활용하여 측정 하였다. 복부비만율은 환자군과 정상군에서뿐만 아니라 (p = 0.03), 전립선암 악성도와 (Gleasonscore; p = 0.001)도 통계적 차이를 나타냈다. 하지만 BMI 결과와는 전립선암 발생과 악성도에서 무관함을 보인 것에 반해 허리둘레는 전립선암의 발생에 영향을 미치는 결과를 나타났다. 한편 전립선암의 또 다른 악성도 지표인 PSA는 비만 측정치와의 상관성이 Gleason score와 보다 대체적으로 낮게 나타났다. 학력, 운동량, 흡연, 음주 상태와 같은 생활 특성에 따른 전립선암 발생의 영향 관계는 뚜렷하지 않았다. 결론적으로 본 연구를 통해서 전립선암의 발생 위험도와 악성도 지표로 복부 비만도가 유용함을 나타냈고 간단한 신체 계측 지표 활용으로는 BMI보다 허리둘레 측정치가 더 암 발생의 연관성이 높음을 보였다.

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Trends of Chuna Manual Therapy on Traffic Accident in Korea from 2005 to 2014 (최근 10년간 교통사고 환자의 추나치료에 대한 국내 연구 동향)

  • Jeon, Yong-Tae;Park, Sang-Hun;Han, Kuk-In;Lee, Jung-Han;Ko, Youn-Seok
    • Journal of Korean Medicine Rehabilitation
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    • v.25 no.2
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    • pp.89-96
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    • 2015
  • Objectives This study is to investigate domestic trends of chuna manual therapy on traffic accident for recent 10 years. Methods We searched the studies on chuna manual therapy for traffic accident in 6 Korean web databases. Consequently, 17 research papers were founded. We analyzed these papers according to their published year, the titles of journal, the type of study, the number of cases, the sites of injury, assessment scales of study, and ethics of research. Results 17 papers were published since 2005. The studies on chuna manual therapy about traffic accident were mainly published in the journal of korean society of chuna manual medicine for spine & nerves and the journal of korean medicine rehabilitation. All papers were clinical research include 2 case series, 2 non randomized controlled trials (NRCTs), 13 randomized controlled trials (RCTs). The most frequently occured symptom was neck pain. In assessment scales, visual analog scale (VAS) was mainly used. All clinical studies were not mentioned about approval of institutional review board (IRB). Conclusions In this study, we analyzed the trends of chuna manual therapy on traffic accident in Korea from 2005 to 2014. In reviewing published papers, we found several weak points in methods of research and quality of study protocol. It is needed to adjust these problems for development of future researches.

A Systematic Review of Clinical Researches of Korean Medicine for Alopecia (탈모증의 한약제제 치료효과에 대한 체계적 문헌 고찰)

  • Ryu, Deok-Hyun;Roh, Seok-Sun
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.30 no.2
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    • pp.1-18
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    • 2017
  • Objectives : This review aims to evaluate a risk of bias by risk of bias tool and RoBANS(Risk of Bias Assessment tool for Non-randomized Study) tool for clinical trial papers proving treatment effect of Korean medicines to alopecia and provides the newest reason of effectiveness of herbs to alopecia. Methods : Data were collected through electronic database including NDSL, KISS, KMBASE, Koreantk, OASIS, KoreaMed, KISTI, Pubmed, Cochrane CENTRAL and CINAHL. Two experts in Oriental Medicine assessed risk of bias of randomized controlled trials by Cochrane group's Risk of Bias tool and non-randomized controlled trials by RoBANS tool after searching, reviewing and selecting papers. Results : Total number of selected trials is 20 including 4 randomized controlled trial, 13 non-randomized controlled trials and 3 case reports. This study evaluate the risk of bias of 17 papers including 4 randomized controlled trials and 13 non-randomized controlled trials except 3 case reports by risk of bias tool and RoBANS tool. All papers of randomized controlled trials are evaluated unclear for random sequence generation and allocation concealment as there are no word on them. And all papers of non-randomized controlled trials are evaluated unclear for blinding of outcome assessments and relatively low for others. Conclusions : Korean medicine intervention can be an effective for treatment in alopecia. It was evaluated by hair density, thickness and expert panel assessment of photographs and all results are statistically significant. But enhancing levels of evidence, we must try to reduce bias in researches and report a safety, protocol and IRB.

Nutritional Assessment of ICU Inpatients with Tube Feeding (경관급식을 공급한 중환자실 환자의 영양상태 평가)

  • Kim, Yu-Jin;Seo, Jung-Sook
    • Journal of the Korean Dietetic Association
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    • v.21 no.1
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    • pp.11-24
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    • 2015
  • This study investigated the general status of tube feeding for intensive care unit (ICU) inpatients and evaluated the consequent nutritional status of patients. This study was approved by the Institutional Review Board (IRB) of a general hospital located in Daegu metropolitan city. The subjects of this study were 80 adult patients who had been admitted to the ICU of a hospital, received fed tube feeding, and then been discharged. The differences in nutrition screening indicators, including percentage ideal body weight (PIBW), serum albumin, hemoglobin, total lymphocyte count, and total cholesterol, before and after tube feeding according to body mass index (BMI) or nutrient feeding levels were investigated. The ratios of actually provided amounts to calorie and protein requirements of patients were $72.8{\pm}15.8%$ and $72.6{\pm}19.8%$, respectively. The change in PIBW before and after tube feeding was significantly different among the BMI groups (P<0.01). The change in hemoglobin concentration before and after tube feeding was also significantly different among the BMI groups (P<0.01). When subjects were divided into three groups (<60%, 60~79%, ${\geq}80%$) according to the ratio of actually provided calories to required calories, there was no significant difference in nutrition screening indicators before and after tube feeding. When the subjects were divided into three groups (<60%, 60~79%, ${\geq}80%$) according to the ratio of actually provided protein to required protein, serum albumin concentration showed a significant difference among the groups before and after tube feeding (P<0.05). Therefore, an intensive nutrition intervention program would be needed for the nutritional improvement of ICU inpatients receiving tube feeding.

Bibliographic Analysis of Articles Published in Journal of Korean Clinical Nursing Research from 2009 to 2015 (임상간호연구 게재논문 분석: 2009년부터 2015년까지)

  • Kim, Yeon Hee;Jeong, Geum Hee;Kwon, In Gak;Kim, Kwang Sung;Moon, Seong Mi;Lee, Jung Lim;Park, Young A
    • Journal of Korean Clinical Nursing Research
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    • v.23 no.1
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    • pp.73-82
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    • 2017
  • Purpose: The aim of this study was to identify bibliographic characteristics and research trends of articles published in the Journal of Korean Clinical Nursing Research from 2009 to 2015. Methods: Descriptive statistics were used to analyze 268 articles. Bibliographic characteristics, appropriateness of methods for quantitative and qualitative studies, and key concepts of articles were analyzed. Results: A clinical nurse was the first author for 184 (66.7%) articles. The number of collaborative works between hospital and university was 184 (68.7%). Study participants were patients (120, 38.1%), nurses (115, 36.5%) and others. IRB approval was given for 156 articles (58.2%). Written informed consent was obtained in 125 articles (46.7%). Quantitative research accounted for 98.6% of the articles but qualitative studies only 4 (1.4%). Types of interventions in the experimental studies were nursing skills (43, 42.6%) and health education (32, 31.7%). Major keywords were nurses, pain, knowledge, intensive care unit, anxiety, depression, fatigue, and stress. Conclusion: Articles in this journal deal with topics and concepts confronted in nursing practice so experimental studies on applicability of nursing interventions were frequently published. Findings in this study indicate that the authors published in the journal contribute to the development of nursing with characteristics distinctive from other nursing journals published in Korea.

Trends in Research Studies Published in Journal of Korean Academy of Fundamentals of Nursing: 2009-2011 (최근 3년간 기본간호학회지 게재 논문 분석)

  • Kim, Kyung-Hee;Chang, Sung-Ok;Kang, Hyun-Sook;Kim, Keum-Soon;Kim, Jong-Im;Kim, Hwa-Soon;Park, Jin-Hee;Eom, Mi-Ran;Won, Jong-Soon;Youn, Mi-Sun;Lee, Og-Cheol
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.19 no.3
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    • pp.383-391
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    • 2012
  • Purpose: The purpose of this study was to identify the trends in research studies published in Journal of Korean Academy of Fundamentals of Nursing from 2009 to 2011. Methods: A total of 156 studies published between 2009 and 2011 were reviewed using analysis criteria developed by the researchers. Results: Quantitative studies accounted for 90.4% and qualitative studies, 8.3%. The research designs for the quantitative studies were experimental, 28.0% and survey, 63.8%. IRB approval was received for only 25.6% of the studies and 61.0% of studies presented participant criteria. Questionnaires were used for data collection in 90.8% of studies. Individual or group education was the most frequent intervention in the experimental studies. Conclusion: The results indicate that more randomized controlled trials with a low risk of bias are needed to support greater evidence-based nursing practice. Considering the low rate of ethical consideration, it is important that stricter application of research methods needs to be encouraged to improve the quality of Journal of Korean Academy of Fundamentals of Nursing.

Effect of E10 on Relief of Cervical Myalgia; One Group Pre-Post, Pilot Trial Study (E10의 경항부 근육통 완화에 대한 효과; 전-후 비교, 예비 임상 연구)

  • Jung, Dong-Hoon;Kim, Hye-Jung;Kim, Jung-Sup;Lee, Gui-Sun;Park, Won-Hyung;Cha, Yun-Yeop
    • Journal of Korean Medicine Rehabilitation
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    • v.26 no.3
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    • pp.119-128
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    • 2016
  • Objectives The purpose of this study is to investigate the efficacy of E10 on the relief of cervical myalgia. Methods This study is a one group pre-post, pilot trial test. After the approval of institutional review board (IRB), we have recruited 25 patients suffering from cervical myalgia. 23 patients (2 patients dropped out) was treated by using E10 on the cervical muscle and acupuncture points, three times a week for a total of two weeks from February 2016 to April 2016. Evaluations of VAS for bothersomeness of neck pain (VASB), VAS for pain intensity (VASP), NDI, SF-36, X-ray, thermography, etc. before and 1 week after treatment were carried out. The primary outcome measure was the VASB, measured 1 week after the end of the therapy. Results VASB scores was significantly decreased from $72.5{\pm}9.9$ to $50.4{\pm}9.9$. VASP scores was significantly decreased from $71.5{\pm}10.5$ to $48.5{\pm}18.3$. Results showed significant improvements in VASB, VASP, NDI, SF-36 from the baseline. However, in X-ray, thermography, there was no singnificant difference. Conclusions This study demonstrates the effectiveness of E10 treatment for relieving cervical myalgia.

Observation on Change of Body Temperature for Patients with Low Back Muscular Pain after Electromagnetic Theraphy: a Randomized, Patient-assessor Blind, Placebo-controlled, Pilot Trial Study (자기를 이용한 경락 자극요법 시행 후 요부근육통 환자의 체열변화 관찰: 무작위배정, 환자-평가자 눈가림, 위기기 대조군, 예비 임상 연구)

  • Cho, Woong-Hee;Park, Won-Hyung;Cha, Yun-Yeop;Sun, Seung-Ho;Lee, Seon-Goo
    • Journal of Korean Medicine Rehabilitation
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    • v.21 no.4
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    • pp.145-156
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    • 2011
  • Objectives: This study was resigned to observe change of body temperature for patients with low back muscular pain after NUGA MRT-II(pulsed electromagnetic therapy) treatment. Methods: This study was a randomized, patient-assessor blind, placebo-controlled, pilot trial study. After the approval of institutional review board(IRB), we have recruited 38 patients suffering from low back muscular pain and divided them into two groups randomly: the treatment group and control group. To the treatment group, NUGA MRT-II was practiced and to the control group sham device was practiced and their low back muscles and acupuncture points three times a week for 2 weeks from February 2011 to May 2011. After 1 week of last treatment, We compared body temperature of two groups. Results: 1. There was significant decrease of body temperature on both Shinsu(BL23), Chishil(BL52), Kwanwonsu(BL26) acupunture points for the treatment group. 2. There was no difference in the decrease of body temperature between treatment group and control group except. Left Kwanwonsu(BL26). Conclusions: We found out that treatment of NUGA MRT-II on low back muscular pain can reduce the temperature of low back.

The Domestic Trends of Traditional Korean Medicine Treatments on Frozen Shoulder (동결견의 한의학적 치료에 대한 국내 연구 동향)

  • Son, Seol-Ki;Kim, Jong-Su;Kim, Shin-Woong;Yoo, Su-Bin;Moon, Byung-Heon;Lee, Cha-Ro
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.9 no.1
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    • pp.55-65
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    • 2014
  • Objectives : The purpose of this review is to investigate the trends of traditional korean medicine treatments on frozen shoulder. Methods : We investigated the studies on traditional korean medicine treatments for frozen shoulder via searching 6 Korean web databases. As a result, 32 research papers were found to be analyzed according to their published year, the titles of journals, published institution, the types of study, the number of cases, the types of treatments, the instruments for assessment and ethical approvals. Results : 32 papers were published since 1989. The studies on traditional korean medicine treatments about frozen shoulder were mainly published in The journal of korean acupuncture & moxibustion medicine. 10 case series, 7 reviews, 6 non-randomized controlled trials, 5 randomized controlled trials and 4 case reports had been under research. In most of the research, the number of the cases were not enough. In 15 cases of the studies, various traditional korean medicine treatments were used to treat the symptoms. In 8 cases of the studies, one method was used to treat the symptoms. Range of motion(ROM) and visual analogue scale(VAS) were used as primary assessments. Among the 25 clinical studies, 5 of them were accepted by institutional review board(IRB). Conclusion : In this study, we analyzed the trends of traditional korean medicine treatments on frozen shoulder. Reviewing the domestic trends of studies on traditional korean medicine treatments for frozen shoulder and examining the strong and weak points of those treatments are essential for the future studies.

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