• 환경생물
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• 제21권1호
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• pp.52-55
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• 2003

There is considerable evidence that ionizing radiation (IR) mediates checkpoint control, repair and cell death. In this study, we have used a high density microarray hybridization approach to characterize the transcriptional response of human breast carcinoma MCF-7 cell line to ${\gamma}$-radiation, such as 4 Gy 4 hr, 8 Gy 4 hr, and 8 Gy 12 hr. We found that exposure to ${\gamma}$-ray alters by at least a $log_2$ factor of 1.0 the expression of 115 known genes. Of the 66 genes affected by ${\gamma}$-radiation, 49 are down-regulated. In our results, the cellular response to irradiation includes induction of the c-jun and EGR1 early response genes. The present work has examined potential cytoplasmic signaling cascades that transduce IR-induced signals to the nucleus. 40S ribosomal protein s6 kinase modulates the activities of the mitogen activated protein kinase (MAPK) and c-Jun $NH_2$-terminal kinase (JNK1) cascades in human monocytic leukemia (U937/pREP4) cells. 14-3-3 family members are dimeric phosphoserine -binding proteins that participate in signal transduction and checkpoint control pathways.

• 한국추진공학회지
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• 제24권6호
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• pp.45-52
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• 2020

초소형 스마트탄의 개발을 위해 초소형 추진기관을 설계하고 그레인은 내부 형상의 제작 용이성을 고려하여 열가소성 추진제로 제작하였다. 추진기관의 성능분석을 위해 지상연소시험과 내탄도 해석이 수행되었다. 그리고 사수와 추진기관 간 안전거리 설계에 대한 기초자료를 획득하기 위하여 수치해석을 수행하였으며, 배기가스의 온도분포는 수치해석과 IR 카메라의 측정결과를 비교하여 분석되었다.

• Journal of Microbiology and Biotechnology
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• 제19권10호
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• pp.1206-1212
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• 2009

Growth rates, photosystem II photosynthesis, and the levels of chlorophyll $\alpha$ and secondary metabolites of Chlorella ovalis were estimated to determine if they were enhanced by the addition of swine urine (BM) or cow compost water (EP) that had been fermented by soil bacteria to deep seawater (DSW) in an attempt to develop media that enabled batch mass culture at lower costs. Growth of C. ovalis in f/2, f/2-EDTA+BM60%, DSW+BM30%, and DSW+EP60% was enhanced and maintained in the log phase of growth for 16 days. The cell densities of C. ovalis in DSW+EP60% ($4.1{\times}10^6$ Cells/ml) were higher than those of f/2 ($2.9{\times}10^6$ Cells/ml), f/2-E+BM60% ($3.7{\times}10^6$ Cells/ml), and DSW+BM30% ($2.7{\times}10^6$ Cells/ml). The growth rate was also more favorable for C. ovalis cultured in DSW+EP60% ($0.15\;day^{-1}$) than that of C. ovalis cultured in the control medium (f/2) ($0.12\;day^{-1}$). Furthermore, the chlorophyll a concentration of C. ovalis cultured in DSW+EP60% (4.56 mg/l) was more than 2-fold greater than that of C. ovalis cultured in f/2 (2.35 mg/l). Moreover, the maximal quantum yields of photo system II at 470 nm (Fv/Fm) were significantly higher in organisms cultured at f/2-E+BM60% (0.53) and DSW+EP60% (0.52) than in the other treatment groups. Finally, Fourier transformation infrared (FT-IR) spectroscopy revealed that C. ovalis grown in DSW+EP60% had more typical peaks and various biochemical pool shifts than those grown in other types of media. Taken together, the results of this study indicate that the use of DSW+EP60% to culture C. ovalis can reduce maintenance expenses and promote higher yields.

• 한국표면공학회지
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• 제27권2호
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• pp.65-73
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• 1994

Effects of deposition parameter on the ionic conductivity and structural change of the Lithium borosili-cate solid electrolyte films, prepared by rf sputtering using 7$LI_2O-3B_2O_3-1SiO_2$ single phase target and also a mosaic target enriched with $LI_2O$, were analyzed by measuring AC impedance and IR absorption spectra for the films. Thed solid electrolyte film deposited from the single phase target exhibited very low ionic conductivi-ty of $10^{-10}{\Omega}^{-1}cm{-1}$ at room temperature, a result of low $Li^+$ ion content(7.52 at%) in the film. The $Li^+$ con-ductivity for the films deposited from the mosaic target, however, significantly increased to $10^{-7}{\Omega}^{-1}cm{-1}$ due to both an increased $Li^+$content (14.75 at %) and a structural change of the films. The increased ionic conduc-tivity of the film appears to be associated with an easiness of ionic mobility by structural change of glassy film from a some close packed network structure to a open one. These structural changes of film were found to be closely related to the increase in the peak intensity at~$960cm^{-1}$ of IR absorption spectra for the glassy films. With increasing either argon pressure from 3 to 21 mtorr or rf power from 2 to 3 W/$cm^2$, the $Li^+$ conduc-tivity for the films significantly increased to an order of $10^{-6}{\Omega}^{-1}cm{-1}$ due to an increase in openness of film structure, as confirmed by both an increase in the IR absorption peak intensity at ~$960cm^{-1}$ and a resultant reduction of activation energy for mobility of $Li^+$ ion.

• 한국화재소방학회논문지
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• 제32권5호
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• pp.52-56
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• 2018

화재로 인한 피해는 열상에 의한 피해보다는 연소 독성에 의한 피해가 치명적이며, 인명피해를 줄이기 위해 화재 상황에서 젖은 수건을 사용하여 화재로부터 발생되는 독성가스를 방호하도록 권장하고 있다. 본 연구에서는 젖은 수건을 통해 실제 화재에서 발생되는 가스를 대상으로 필터링 효과를 정량화하였다. 화재가스 중 세 가지 가스($CO_2$, HCl, HCN)를 대상으로 젖은 수건의 필터효과를 확인하기 위해 FT-IR을 이용하여 필터를 통과한 가스를 실시간 분석을 하였으며, 물에 잘 녹지 않는 $CO_2$에 비해 유독가스이며, 수용성 가스인 HCl, HCN은 젖은 수건에 의해 가스가 필터링 되면서 가스 검출 시점이 지연됨을 확인하였다. 따라서 실제 화재 시 독성가스 중 특히 수용성 가스의 경우 젖은 수건을 이용하게 되면 일정 시간 피난 시간을 확보할 수 있음을 확인하였다.

• Bulletin of the Korean Chemical Society
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• 제33권11호
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• pp.3645-3650
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• 2012

Two new blue emitting cationic iridium(III) complexes with two substituted 2-phenlypyridine ligands as main ligands and one 2,2'-biimidazole as an ancillary ligand, $[(L1)_2Ir(biim)]Cl$ (1) and $[(L2)_2Ir(biim)]Cl$ (2), where L1 = 2-(2',4'-difluorophenyl)-4-methylpyridine, L2 = 2-(2',4'-difluoro-3'-trifluoromethylphenyl)-4-methylpyridine and biim = 2,2'-biimidazole, were synthesized for applications in phosphorescent organic light-emitting diodes (PhOLEDs). Their photophysical, electrochemical and electroluminescent (EL) device performances were examined. The photoluminescent (PL) spectra revealed blue phosphorescence in the 450 to 485 nm range with a quantum yield of more than 10%. The iridium(III) compounds studied showed good solubility in organic solvents with no solvatochromism dependent on the solvent polarity. The solution-processed OLEDs were prepared with the configuration, ITO/PEDOT:PSS (40 nm)/mCP:Ir(III) (70 nm)/OXD-7 (20 nm)/LiF (1 nm)/Al (100 nm), by spin coating the emitting layer containing the mCP host doped with the iridium phosphors. The best performance of the fabricated OLEDs based on compound 1 showed an external quantum efficiency of 4.5%, luminance efficiency of 8.52 cd $A^{-1}$ and blue emission with the CIE coordinates (x,y) of (0.16, 0.33).

• Clinical and Experimental Reproductive Medicine
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• 제50권3호
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• pp.200-205
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• 2023

Objective: Polycystic ovary (PCO), a diagnostic component of polycystic ovary syndrome (PCOS), requires either an ovarian volume (OV) criterion or a follicle number per ovary (FNPO) criterion. This study investigated the association of OV and FNPO criteria with various manifestations of PCOS. Methods: This cross-sectional study was conducted at a university hospital among 100 patients newly diagnosed with PCOS (according to the revised Rotterdam criteria). Fasting blood samples were collected to measure glucose, total testosterone (TT), luteinizing hormone (LH), follicle-stimulating hormone (FSH), lipid, insulin, and hemoglobin A1c levels. An oral glucose tolerance test was performed. Transabdominal or transvaginal ultrasound of the ovaries was done, depending on patients' marital status. All investigations were conducted in the follicular phase of the menstrual cycle. OV >10 mL and/or FNPO ≥12 indicated PCO. A homeostasis model assessment of insulin resistance (IR) value ≥2.6 indicated IR, and metabolic syndrome (MS) was defined according to the international harmonization criteria. Results: Seventy-six participants fulfilled the OV criterion, 70 fulfilled the FNPO criterion, and 89 overall had PCO. Both maximum OV and mean OV had a significant correlation with TT levels (r=0.239, p=0.017 and r=0.280, p=0.005, respectively) and the LH/FSH ratio (r=0.212, p=0.034 and r=0.200, p=0.047, respectively). Mean OV also had a significant correlation with fasting insulin levels (r=0.210, p=0.036). Multivariate binary logistic regression analysis showed that IR (odds ratio [OR], 9.429; 95% confidence interval [CI], 1.701 to 52.271; p=0.010) and MS (OR, 7.952; 95% CI, 1.821 to 34.731; p=0.006) had significant predictive associations with OV alone, even after adjustment for age and body mass index. Conclusion: OV may be more closely related to the androgenic and metabolic characteristics of PCOS than FNPO.

• 천문학회보
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• 제46권2호
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• pp.40.2-40.2
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• 2021

The impact of AGN on star formation is one of the main questions in AGN-galaxy coevolution studies. However, direct evidence of AGN feedback is still rare. One of the main obstacles is that various star formation rate (SFR) indicators are contaminated by AGN contribution. We present IR-based SFR measurements of a sample of 52 local (z<0.3) AGNs, which were selected based on kinematical properties of ionized gas outflows, using SED analysis with JCMT/SCUBA-2 data. First, we will compare IR-based SFR with other SFR indicators to check the reliability of the SFR indicators. Second, we will discuss the contribution of Mid-IR emission from hot dust of AGN torus by comparing SED fitting results with and without including AGN dust component. Finally, we will report the correlation between specific SFR (sSFR) and AGN activity (e.g., outflow strength or Eddington ratio) as evidence of no instantaneous feedback and discuss the implications of these results

• 한국자기학회지
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• 제23권6호
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• pp.193-199
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• 2013

NiFe/Cu/NiFe/IrMn/NiFe/Cu/NiFe 이중구조 GMR-SV 박막의 열처리 조건에 의존하는 자기등방성 영역분포 특성을 조사하였다. 진공 챔버내에서 이중구조 GMR-SV 박막을 후열처리 온도를 조절하여 면상에서 강자성체 층의 자화용이축 회전을 유도하였다. 자유층과 고정층의 자화용이축 방향에 의존하는 이중구조 GMR-SV 박막의 자기저항곡선은 외부자기장의 각도를 $0^{\circ}$에서 $360^{\circ}$까지 변화시킨 후 외부자기장의 세기에 따라서 측정하였다. 후열처리 온도가 $107^{\circ}C$일 때, 외부자기장의 방향이 $0^{\circ}$에서 $90^{\circ}$까지 영역에서 자장감응도가 약 1.52 %/Oe인 자기등방성 특성을 보였다. 이러한 특성은 고정층과 자유층을 형성하는 강자성층들이 면상에서 서로 직교한 결과임을 나타내며, 자기등방성 GMR-SV 박막 소자는 임의 방향으로 자화된 마이크로 자성비드를 검출할 수 있는 고감도 바이오센서로 사용할 가능성을 제시하였다.

• 한국식품영양과학회지
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• 제26권1호
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• pp.72-80
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• 1997

식용 및 약용으로 이용한 역사가 오래인데도 불구하고 구성성분의 조성에 대하여 충분한 연구가 되어 있지 않은 해삼에서 당단백질과 황산콘드로이친을 추출정량하여 이들의 화학적 조성과 구조적 특성을 GC. MS및 IR로 검토하였다. 동결건조 해삼분말의 화학적인 조성은 sulfate esters함량이 0.90~l.21%, 다당류 함량이 23.08~26.97%였고 이를 구성하고 있는 구성단당류는 fucose의 함량이 30%이상을 차지하는 것을 비롯하여 glucose, N-acetylglucosamine, mannuronic acid, ribose의 5종이 거의 88%이상을 차지하고 있었고 그외 mannose, galactose, N-acetylgalactosaminne, D-glucuronic acid도 소량 검출되었다. 추출당단백질의 sulfate esters의 함량은 0.96~l.13%, 다당류의 함량은 58.7%~62.7%로 나타나고 주요 구성당은 fucose가 30%내외로 가장 많았으며 mannose, glucose와 ribose가 86%이상을 차지하며 galactose, N-acetylgalactosamine, D-glucuronic acid, N-acetylglucosamine도 소량 함유하고 있었다. 동결건조 해삼분말에서 추출한 황산콘드이친의 황산기의 함량은 3.52~3.72%이었다. 이들의 구성성분은 fucose, N-acetylgalactosamine 및 D-glucuronic acid 이며 IR spectrum에서 1240$cm^{-1}$ /의 S=0신축진동과 850$cm^{-1}$ /나 820$cm^{-1}$ /의 C-O-S 신축진동이 나타나 fucose의 $C_4$의 결합위치를 나타내고 있었다.