• Proceedings of the Microbiological Society of Korea Conference
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• 2005.05a
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• pp.159-161
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• 2005

Hypovirus infection of the chestnut blight fungus Cryphonectria parasitica is a useful model system to study the hypoviral regulation of fungal gene expression. The hypovirus is known to downregulate the fungal laccase1 (lac 1), the modulation of which is tightly governed by the inositol triphosphate ($IP_3$) and calcium second messenger system in a virus-free strain. We cloned the gene cplc1 encoding a phosphatidyl inositol-specific phospholipase C (PLC), in order to better characterize the fungal gene regulation by hypovirus. Sequence analysis of the cplc1 gene indicated that the protein product contained both the X and Y domains, which are the two conserved regions found in all known PLCs, with a 133 amino acid extension between the 2nd ${\beta}$-strand and the ${\alpha}$-helix in the X domain. In addition, the gene organization appeared to be highly similar to that of a ${\delta}$ type PLC. Disruption of the cplc1 gene resulted in slow growth and produced colonies characterized by little aerial mycelia and deep orange in color. In addition, down regulation of lac1 expression was observed. However, temperature sensitivity, osmosensitivity, virulence, and other hypovirulence-associated characteristics did not differ from the wild-type strain. Functional complementation of the cplc1-null mutant with the PLC1 gene from Saccharomyces cerevisiae restored lac1 expression, which suggests that the cloned gene encodes PLC activity. The present study indicates that the cplc1 gene is required for appropriate mycelial growth, and that it regulates the lac1 expression, which is also modulated by the hypovirus. Although several PLC genes have been identified in various simple eukaryotic organisms, the deletion analysis of the cplc1 gene in this study appears to be the first report on the functional analysis of PLC in filamentous fungi.

• Journal of the Korean earth science society
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• v.31 no.7
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• pp.708-719
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• 2010

The Gochang-gun Dongho macro-tide pocket-type beach, located on the southwestern coast of Korea, is investigated in terms of the seasonal variations of surface sediment and sedimentary environment. Surface sediments of 45 sites in four seasons (May 2006-February 2007) are sampled across three survey lines (15 sites in each survey line). The surface sediments of the Dongho Beach are mainly composed of fine to coarse sands, and the ratio of fine sand is the largest. The average of grain size is the coarsest in the summer. The spatial distribution of surface sediments shows a coast-parallel band of fine and medium sands during three seasons of spring, fall, and winter, whereas medium sands dominated in the northern part of the study area during the summer. These results suggest that a tide is more effective than a wave in the surface sediments of the Dongho Beach during the summer.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.11
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• pp.2423-2428
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• 2010

The number of motor vehicle registrations in Korea is increasing steadily each year, driven by industry development and economic growth. The number of traffic accidents is also rapidly increasing. Korea has a relatively high number of traffic accidents among OECD member countries, and it ranks among the highest in traffic accident death rates. This death rate is higher compared to death rates as a proportion of the number of traffic accidents in each country. It is very common for drivers to lose consciousness in traffic collisions, which leads to a failure to carry out early emergency measures. In order to prevent such situations as well as hit-and-runs and people left uncared for after traffic accidents, there is a need for motor vehicle black boxes and accident report systems. This study addressed the need for an emergency evacuation system for people injured in traffic accidents and a secondary traffic accident prevention system by developing a motor vehicle emergency situation detection and report system combined with a black box, and materializing it as an actual system.

• Proceedings of the Korea Information Processing Society Conference
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• 2017.04a
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• pp.315-318
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• 2017

Nowadays, Distributed Denial of Service (DDoS) attacks have gained increasing popularity and have been a major factor in a number of massive cyber-attacks. It could easily exhaust the computing and communicating resources of a victim within a short period of time. Therefore, we have to find the method to detect and prevent the DDoS attack. Recently, there have been some researches that provide the methods to resolve above problem, but it still gets some limitations such as low performance of detecting and preventing, scope of method, most of them just use on cloud server instead of network, and the reliability in the network. In this paper, we propose solutions for (1) handling multiple DDoS attacks from multiple IP address and (2) handling the suspicious attacks in the network. For the first solution, we assume that there are multiple attacks from many sources at a times, it should be handled to avoid the conflict when we setup the preventing rule to switches. In the other, there are many attacks traffic with the low volume and same destination address. Although the traffic at each node is not much, the traffic at the destination is much more. So it is hard to detect that suspicious traffic with the sampling based method at each node, our method reroute the traffic to another server and make the analysis to check it deeply.

• The Journal of Korean Medicine
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• v.33 no.2
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• pp.47-55
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• 2012

Objectives: This study aimed to investigate the preventive effect of red ginseng (RG) on 5-fluorouracil (5-FU)-induced side effects focusing on myelosuppression. Methods: Rats (n = 50) were divided into five groups, nave, control (ip, 5-FU injection of 150 mg/kg), and RG pre-treatment (po, 25, 50 and 100 mg/kg for 5 days before 5-FU injection). On the $7^{th}$ day after 5-FU injection, we evaluated the effects using peripheral hematological parameters, colony-forming assay, cytokine levels and histopathological finding. Results: The peripheral white blood cell and the differential count were dramatically suppressed by 5-FU, while RG (50 and 100 mg/kg) treatment significantly improved total white blood cell, neutrophil, lymphocyte and platelet counts. Also, RG (100 mg/kg) pre-treatment significantly increased the number of CFU-GM colony compared with the control group. RG pre-treatment also ameliorated the histopathological damage in bone marrow, spleen, stomach and small intestine tissue. Conclusions: These results demonstrate that Korean RG has preventive effects against 5-FU-induced myelotoxicity and gastrointestinal damage.

• Journal of KIISE:Computing Practices and Letters
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• v.14 no.2
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• pp.181-185
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• 2008

Layered video multicast such as RLM Receiver-driven layered multicast) is a premising technique for delivering streaming video to a set of heterogeneous receivers over ALM(Application Layer Multicast) as well as over IP multicast. However, this approach may suffer from unnecessary fluctuation of video quality due to overlapped and failed join-experiments. Though a shared teaming scheme was introduced to resolve these problems, it may cause high control overhead and slow convergence problem when used with ALM. In this paper, we propose a new shared learning scheme for ALM-based layered video multicast which reduces control overhead and convergence latency while keeping the number of fluctuation reasonably small. The simulation results show that the proposed scheme performs better than an ALM-based layered video multicast with shared learning in terms of control overhead and convergence latency.

• The Korean Journal of Pain
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• v.25 no.4
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• pp.238-244
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• 2012

Background: Vitamin E is widely known to be one of the reactive oxygen species (ROS) scavengers and a drug that can easily be obtained, and it has been shown to attenuate the pain responses induced by various causes in animal pain models. Thus, this experiment was conducted to assess the antinociceptive effects of vitamin E by comparing intraperitoneal and intrathecal injections in rats subjected to the formalin test. Methods: After the intraperitoneal and intrathecal injections of vitamin E were carried out, respectively (IP: 500 mg/kg, 1 g/kg, and 2 g/kg, IT: 3 mg/kg, 10 mg/kg, and 30 mg/kg), the formalin test was perfumed. As soon as 5% formalin was injected into left hind paw, the number of flinches induced by pain was measured at 5-minute intervals for 1 hour. Results: Formalin injected into the left hind paw induced biphasic nociceptive behavior in all animals. Intraperitoneal injection of vitamin E diminished the nociceptive behavior in a dose-dependent manner during the early and late phase. Intrathecal vitamin E diminished nociceptive behavior dose dependently during the late phase but showed no significant difference in the early phase. Conclusions: Vitamin E attenuated acute nociception when it was injected systemically, while both systemic and intrathecal injection produced analgesia in a rat model of formalin-induced hyperalgesia.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.9A
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• pp.838-849
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• 2005

Fast handover protocol provides seamless handover in mobile Ipv6 networks by reducing handover latency. This paper proposes FMIP-M mechanism to apply this advantage of fast handover protocol to multicast service. The FMIP-M is a fast handover mechanism that supports a reliable multicast service in mobile Ipv6 networks. When hosts move other networks, they may have seine data missing and out-of-synch problems of multicast data. The proposed mechanism provides reliable multicast transmission by compensating data losses from the previous AR. Also it provides an additional function that is able to change multicasting service types dynamically in accordance with network status related with multicasting. So that it is able to make multicast paths very close to the optimum and more efficient multicast service is possible. The performance of the proposed mechanism is evaluated by a time analysis and simulations in various conditions.

• Journal of Communications and Networks
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• v.8 no.2
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• pp.234-240
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• 2006

We study the dynamic burst assembly based on traffic prediction and offset and delay differentiation in optical burst switching network. To improve existing burst assembly mechanism and build an adaptive flexible optical burst switching network, an approach called quality of service (QoS) based adaptive dynamic assembly (QADA) is proposed in this paper. QADA method takes into account current arrival traffic in prediction time adequately and performs adaptive dynamic assembly in limited burst assembly time (BAT) range. By the simulation of burst length error, the QADA method is proved better than the existing method and can achieve the small enough predictive error for real scenarios. Then the different dynamic ranges of BAT for four traffic classes are introduced to make delay differentiation. According to the limitation of BAT range, the burst assembly is classified into one-dimension limit and two-dimension limit. We draw a comparison between one-dimension and two-dimension limit with different prediction time under QoS based offset time and find that the one-dimensional approach offers better network performance, while the two-dimensional approach provides strict inter-class differentiation. Furthermore, the final simulation results in our network condition show that QADA can execute adaptive flexible burst assembly with dynamic BAT and achieve a latency reduction, delay fairness, and offset time QoS guarantee for different traffic classes.

• Convergence Security Journal
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• v.14 no.2
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• pp.11-16
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• 2014

Recently, request of IPTV was increase. It is a multi-screen service by used TV, PC, and smart-phones. Especially, IPTV and smart-phone linked multi-screen service are very growth by user's recommends. Now, IPTV have a security service partial and multi-screen service. But smart-phone and multi-screen service don't have security service. And authentication service for smart-phone and IPTV linked multi-screen service is don't.. Therefore, We propose that user authentication system for multi-screen service with IPTV and multi-device linked authentcation services. Our proposed system base on Kerberos, so proposal is easy and fast about user authentication. This have simple procedures and more secure services against of PKI. So, our system can support secure multi-screen services against various security threats in multi-screen environments.