• 한국임상수의학회지
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• 제29권6호
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• pp.447-454
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• 2012

본 실험에서는 propofol과 remifentanil 병용 마취법 사용 시 안압 및 혈액학적 변화를 측정하고 isoflurane 마취 결과와 비교하였다. 건강한 14마리의 비글견을 7마리씩 2군 (PRP군, ISF군)으로 나누었으며 PRP군은 마취 도입 10분 전에 acepromazine (0.05 mg/kg, IV)으로 전마취제 투여하고 atracurium 0.1 mg/kg 투여 후, propofol (5 mg/kg, IV)으로 마취 유도하였다. 마취 유지에는 propofol (0.2 mg/kg/min)과 remifentanil ($0.5{\mu}g/kg/min$)을 사용하였다. ISF군에서는 propofol (5~7 mg/kg, IV)로 마취를 유도하고, isoflurane 흡입마취법으로 마취를 유지하였다. 초기 isoflurane 농도를 3%으로 유지하다가 마취가 안정된 후 1.9%로 낮추어 유지 하였다. 모든 군에서 간헐적인 100% 양압 호흡을 사용해 $CO_2$는 38에서 45 mmHg사이를 유지하고 $SpO_2$는 95에서 100사이를 유지하였다. 총 마취 시간은 90분이었으며 안압, 혈압, 심박수를 각각 5, 10, 15, 30, 45, 60, 75, 90에 측정을 하였다. 실험 결과 propofol과 remifentanil 병용마취법이 isoflurane 흡입마취법 보다 안정적으로 안압과 혈압을 낮출 수 있었다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2002년도 학술발표회 논문집(II)
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• pp.1179-1186
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• 2002

Macro scale distributed hydrological models simulate river discharge with better accuracy but it depends upon the grid resolution of input data. Effects of different input resolutions are studied here. Three different grid resolution input data obtained from HUBEX-IOP EEWB data and GAME Re-analysis data are used to simulate river discharge and compared against the observed one. CAME Re-analysis 1.25-degree resolution data are found quite satisfactory in larger basins, while HUBEX-IOP EEWB 10-minute resolution data are better for small catchments. GAME Re-analysis 2.5-degree resolution data did not give good result. Simulated results by using spatially interpolated data are rather worse than using original data. The Huaihe River basin $(132350\textrm{km}^2)$ is taken as the case of study.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2004년도 하계학술대회 논문집 A
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• pp.171-173
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• 2004

This paper presents the selection of optimal placement for STATCOM (Static synchronous Compensator) which is one of the FACTS (Flexible Alternating Current Transmission System) devices, considering line contingency. Line contingency ranking is gotten by using sensitivity of load margin. According to line contingency ranking line contingency was considered. And IOP (Index for selecting optimal Placement of STATCOM) is calculated by the variation of each bus's reactive mum for several line contingencies. The bus where has the biggest value of lOP is the most optimal placement to install STATCOM for voltage stability. IPLAN is used to program this part which get IOP. This study is carried out on the modified IEEE14 Bus Test System to confirm the efficiency of the method.

• 한국정보컨버전스학회논문지
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• 제7권2호
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• pp.25-29
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• 2014

본 연구에서는 알코올 섭취가 눈의 생리기능과 안기능에 영향을 미치는 가를 알아보기 위해 알코올 섭취 전,후의 안압, 누액분비량, 입체시차, AC/A비, 폭주여력, 개산여력을 측정하여 다음과 같은 결과를 얻었다. 전체 대상자의 알코올 섭취 전 평균 안압은 15.14mmHg이고 알코올 섭취 후 평균 안압은 12.8mmHg로 평균 15.44% 감소하는 것으로 나타났다. 누액분비량은 알코올 섭취 전 검사대상자 평균 17.125mm에서 알코올 섭취 후 평균 9.875mm로 42.33%로 감소하는 것으로 나타났다. 입체시차는 알코올 섭취 전 40'에서 알코올 섭취 후 165'로 약 4배가량 증가하였다. AC/A비는 알코올 섭취 전 $5.40{\Delta}/D$, 알코올 섭취 후 $6.19{\Delta}/D$로 14.6% 증가하였고 폭주여력과 개산여력은 원거리, 근거리 모두 유의한 변화가 없는 것으로 나타났다.

• 한국자동차공학회논문집
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• 제22권5호
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• pp.126-135
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• 2014

This paper describes the development and verification of control algorithms for V2X and environmental sensor integrated intersection support and safety systems. The objective of the research is to develop core technologies for effective fusion of V2X and environmental sensors and to develop new safety function for intersection safety. One of core technologies is to achieve the improvement of GPS accuracy, and the other is to develop the algorithm of a vehicle identification which matches all data from V2X, vehicle sensors and environmental sensors to specific vehicles. A intersection optimal pass (IOP) algorithm is designed based on these core technologies. IOP recommends appropriate speed to pass the intersection in the consideration of traffic light signal and preceeding vehicle existence. Another function is developed to prevent a collision avoidance when car crash caused by traffic violation of surrounding vehicles is expected. Finally all functions are implemented and tested in three test vehicles. It is shown that IOP can support convenient and comfortable driving with recommending optimal pass speed and collision avoidance algorithm can effectively prevent collision caused by traffic sign violation of surrounding vehicles.

• 한국임상수의학회지
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• 제25권5호
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• pp.385-390
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• 2008

The purpose of this study was to compare the long term prognosis of Ahmed valve implantation and medical therapy in dogs with early primary glaucoma. The medical records of dogs with early primary glaucoma from the Veterinary Medical Teaching Hospital of Seoul National University between January 2005 and May 2008 were reviewed. Five dogs underwent Ahmed valve implantation and medical therapy was performed in six dogs. Breeds of the dogs included Shih Tzu(n = 7), American cocker spaniel(n = 2), and miniature poodle(n = 2). Adequate intraocular pressure(IOP) was better maintained in the Ahmed valve implantation group than in the medical treatment group throughout the follow-up period. Mean time for vision loss to develop after treatment in the Ahmed valve implantation group($198.0{\pm}115.4$ days) was significantly longer than that in medical treatment group($43.2{\pm}30.4$ days, p < 0.05). Post-operative complications included occlusion of the tube by fibrin in the anterior chamber (n = 1), fibrous capsule about the episcleral base of the device(n = 1), and dislocation of the valve body(n = 1). It is considered that Ahmed valve implantation is more effective strategy to control IOP and maintain vision than medical treatment in early glaucomatous dogs.

• 한국환경과학회지
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• 제33권1호
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• pp.75-85
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• 2024

An intensive observing period (IOP) of heatwaves in the urban region of Seoul in the summer of 2023 was carried out to understand the changes in air temperature and road temperature induced by environmental conditions. The temperature observed at eight points with different urban environmental conditions was compared with the temperature by the KMA/AWS to analyze the characteristics of change in air temperature by height and the change in road temperature according to environmental conditions and road sprinkler. The comparison of the average temperature observed in different urban environmental conditions with the temperature observed at KMA/AWS showed that the air temperature in asphalt and open space sites was 0.7 to 2.3℃ higher and that the one in bus stops was 0.9 to 2.3℃ higher. In terms of temperature deviations depending on residential type, the temperature in highly populated areas was about 0.1 to 0.8℃ higher than that of apartment complexes. In addition, regardless of the size of a park, the temperature in the park was lower than the temperature in dense housing areas and apartment complexes. In asphalt and residential areas, the road temperature was higher than the temperature at a height of 150 cm, Conversely, road temperature was lower than air temperature in a shaded shelter and large park. In addition, after spraying a surface road, the road temperature immediately dropped by about 3 to 4℃; however, after about 20 minutes, it rose again to the previous road temperature. This change in road temperature appeared only for the temperature of 30 cm height.

• The Korean Journal of Physiology and Pharmacology
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• 제28권4호
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• pp.345-359
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• 2024

Deposition of extracellular matrix (ECM) in the trabecular meshwork (TM) increases aqueous humour outflow resistance leading to elevation of intraocular pressure (IOP) in primary open-angle glaucoma, which remains the only modifiable risk factor. Resveratrol has been shown to counteract the steroid-induced increase in IOP and increase the TM expression of ECM proteolytic enzymes; however, its effects on the deposition of ECM components by TM and its associated pathways, such as TGF-β-SMAD signalling remain uncertain. This study, therefore, explored the effects of trans-resveratrol on the expression of ECM components, SMAD signalling molecules, plasminogen activator inhibitor-1 and tissue plasminogen activator in dexamethasone-treated human TM cells (HTMCs). We also studied the nature of molecular interaction of trans-resveratrol with SMAD4 domains using ensemble docking. Treatment of HTMCs with 12.5 µM trans-resveratrol downregulated the dexamethasone-induced increase in collagen, fibronectin and α-smooth muscle actin at gene and protein levels through downregulation of TGF-β1, SMAD4, and upregulation of SMAD7. Downregulation of TGF-β1 signalling by trans-resveratrol could be attributed to its effect on the transcriptional activity due to high affinity for the MH2 domain of SMAD4. These effects may contribute to resveratrol's IOP-lowering properties by reducing ECM deposition and enhancing aqueous humour outflow in the TM.

• 대한시과학회지
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• 제20권4호
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• pp.461-468
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• 2018

목적 : 전기를 띄는 천연광석물질인 토르말린을 안경 전체부분에 적용하여 인간의 안구 내 신진대사에 관련된 요소들 중 하나인 안압(Intraocular pressure: IOP)의 변화를 관찰하였다. 방법 : 안경테의 주재료인 TR-90과 토르말린 7 wt%을 혼합하여 안경테를 제작 후, 20대의 90명(남자 46명, 여자 44명)을 대상으로 토르말린 안경테의 착용 전과 후의 안압변화를 정상 안압범위에서 Low, Middle, High 그룹으로 안압에 따라 나누어 관찰하였다. 결과 : 토르말린 안경테를 착용 후, 우안에서 전체안압은 -4.14 %로 감소하였고(p<0.000), High와 Middle 그룹에서 각각 -6.39 %(p<0.000), -4.64 %(p<0.017)로 유의하게 감소하였다. 좌안에서 전체안압은 -2.74 %(p<0.004)로 감소하였고, High 그룹에서만 -4.58 %(p<0.000)로 통계적으로 유의한 값을 나타내었다. 결론 : 본 연구에서 제작한 7 wt% 토르말린이 함유된 안경테를 사용하여, 안경테를 착용 후 안압이 유의하게 감소되어 정상 안압범위의 평균 수치와 근접해지는 것을 확인할 수 있었다. 이러한 연구결과로 인해 신체의 신진대사와 혈액순환을 촉진시키는 효과를 가진 토르말린을 안경테에 접목함으로써 안압의 정상화에 대한 효과를 나타내는 것으로 확인할 수 있었다.

• 한국대기환경학회지
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• 제29권5호
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• pp.682-691
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• 2013

The aerosol extinction vertical profile and surface visibility have been derived from the Microtops-II sunphotometer observation during the winter 2011 intensive observation period (IOP) at Seoul, Korea. Using models of degradation of aerosol optical thickness (AOT) and aerosol scale height, we have performed extinction-visibility modulation to determine the height dependent aerosol extinction and visibility. It is shown that the aerosol loading is relatively low during IOP (mean $AOT_{550}=0.22{\pm}0.08$, ${\AA}$ngstr$\ddot{o}$m exponent=$1.14{\pm}0.26$). Modeled extinction by use of Microtops II sunphotometer data shows good agreement with measurements by the Multi-wavelenth Polarization Lidar (MPoLAR), and the derived surface visibility are consistent with data from the transmissometer. These results emphasize the use of a vertically resolved extinction from AOT to predict visibility conditions at ground level.