• Title/Summary/Keyword: INN

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Investigation of International Nonproprietary Names (INN) Nomenclature System For Biotechnological Products (생명공학의약품의 국제일반명 명명체계 조사)

  • Kim, Eun-Sook;Song, Jae-In;Moon, A-Ree
    • Toxicological Research
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    • v.23 no.2
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    • pp.179-187
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    • 2007
  • An International Nonproprietary Name (INN) identifies a pharmaceutical substance or active pharmaceutical ingredient by a unique name that is globally recognized and is of public property. Also known as the generic or common names, the official INNs are provided by national and international nomenclature bodies such as United States Adopted Names (USAN), British Approved Names (BAN), Japanese Accepted Names (JAN) and World Health Organization (WHO). Due to the increasing interest on the development of biotechnological products in Korea, needs for the formulated nomenclature body in Korea are arising for systemic management of newly developed biotechnological products. This study investigated and analyzed nomenclature systems and procedures for the selection of recommended INN for biotechnological products in WHO, USAN and JAN. Based on these documents from advanced countries, we suggested a Korean INN nomenclature organization named KAN (Korean Adopted Names or Korean Agreed Names). Composition and roles of KAN and KAN expert committee and a working process for INN selection/approval were also proposed. Taken together, this study provides a detailed information on INN system recognized worldwide and suggests guidelines for establishment of INN nomenclature system for biotechnological products in Korea.

The Intrinsic Topology on a Quandle

  • Kim, Byeorhi;Bae, Yongju;Kim, Eun Sup
    • Kyungpook Mathematical Journal
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    • v.57 no.4
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    • pp.711-719
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    • 2017
  • Let Inn(Q) denote the inner automorphism group on a quandle Q. For a subset M of Q, let c(M) denote the orbit of M under the Inn(Q)-action on Q. Then c satisfies the axioms of the closure operator. In this paper, we study the topological space Q corresponding to the topology obtained from the closure operator c.

Municipal Solid Waste-derived Syngas Fermentation Process by Pressurization (가압을 통한 도시형 생활 폐기물 기반 합성가스발효 공정 개발)

  • Subin Shin;Jae Hee Go;Myounghoon Moon;Min-Sik Kim;Mungyu Lee;In Seop Chang;Seongsoo Son;Gwon Woo Park
    • New & Renewable Energy
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    • v.19 no.4
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    • pp.35-45
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    • 2023
  • Global efforts are focused on achieving carbon neutrality due to the increases in the levels of greenhouse gases. Moreover, the greenhouse gases generated from the disposal of municipal solid waste (MSW) are the primary sources of emissions in South Korea. In this study, we conducted the biological conversion of syngas (CO, H2, and CO2) generated from MSW gasification. The MSW-derived syngas was used as a feed source for cultivating Eubacterium limosum KIST612, and pressurization was employed to enhance gas solubility in culture broth. However, the pH of the medium decreased owing to the pressurization because of the CO2 in the syngas and the cultivation-associated organic acid production. The replacement of conventional HEPES buffer with a phosphate buffer led to an approximately 2.5-fold increase in acetic acid concentration. Furthermore, compared with the control group, the pressurized reactor exhibited a maximum 8.28-fold increase in the CO consumption rate and a 3.8-fold increase in the H2 consumption rate.