• Biomedical Science Letters
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• v.25 no.3
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• pp.275-281
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• 2019

This study was performed to characterize the chromosomal metallo-${\beta}$-lactamases (MBLs) of Chryseobacterium indologenes isolated from Korea and to propose a clustering method of IND MBLs based on their amino acid similarities. Chromosomal MBL genes were amplified by PCR from 31 clinical isolates of E. indologenes. Nucleotide sequencing was performed by the dideoxy chain termination method using these PCR products. Antimicrobial susceptibilities were determined by the agar dilution method. PCR experiments showed that all 31 E. indologenes isolates contained all $bla_{IND}$ genes. DNA sequence analysis revealed that E. indologenes isolates possessed ten types of $bla_{IND}$ gene, including seven novel variants ($bla_{IND-8}$ to $bla_{IND-14}$). The most common combination of MBL was IND-2 (n = 18). Minimum inhibitory concentrations of imipenem and meropenem for the isolates harboring novel IND MBLs were ${\geq}16{\mu}g/mL$. IND MBLs were grouped in three clusters, based on amino acid similarities.

• Proceedings of the Materials Research Society of Korea Conference
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• 1998.08a
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• pp.153.2-153
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• 1998

• The Journal of the Korea Contents Association
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• v.18 no.5
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• pp.105-114
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• 2018

Ninhydrin traditionally used to develop fingerprints on paper is often limited in its use depending on background color and its enhancement effect differs depending on reagent reaction condition. Recently 1,2-indanedione(1,2-IND), etc. which has no limitation of background color has been used to visualize the fingermark on paper. Therefore, this study was carried out for enhancement of fingerprints after 1,2-IND/Zn treatment on paper treated with ninhydrin. Comparison between 1,2-IND/Zn reaction after ninhydrin treatment and single ninhydrin reaction were conducted under various methods. Result shows the fingerprints were enhanced when ninhydrin-treated fingerprints were treated with 1,2-IND/Zn, and their enhancement was observed even after 6 months.

• Analytical Science and Technology
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• v.34 no.3
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• pp.122-127
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• 2021

A mixture of polyvinylpyrrolidone and 1,2-indanedione (PVP-IND) is known to be the best reagent for developing latent fingerprints deposited on the surface of a thermal paper. However, no study has evaluated whether PVP-IND could enhance fingerprints in blood deposited on the surface of thermal paper. Therefore, in this study, the ability of PVP-IND to enhance the fingerprints in blood was investigated. Furthermore, aqueous amido black solution, which is known to be the best reagent for enhancing fingerprints in blood deposited on the surface of thermal paper, was used for comparison with PVP-IND. Therefore, while enhancing the fingerprints in diluted blood, PVP-IND enhanced the quality of fingerprints compared to aqueous amido black solution. The ridge diffused when the undiluted fingerprints in blood were enhanced with PVP-IND because PVP reacted with amino acids in blood; however, amido black solution yielded better results. When treated with PVP-IND, it is presumed that the ridge diffused due to the reaction of PVP and amino acids contained in the blood.

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.154.2-155
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• 2003

Recently, we developed a new anti-osteoporotic agent, DW-1350, which not only inhibited osteoclast formation but also induced osteoblast differentiation through the in vitro randomized screening studies. We identified inhibitory activities of DW-1350 for each step of osteoclast differentiation, fusion and pit formation process in co-culture system with mouse bone marrow and primary osteoblasts. (omitted)

• Archives of Pharmacal Research
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• v.22 no.2
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• pp.208-212
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• 1999

Activity-guided fractionation of the roots of Anthriscus sylvestris resulted in the isolated and characterization of five cytotoxic compounds, deoxypodophyllotoxin (1), falcarindiol (2), and angeloyl podophyllotoxin (5) from the hexane soluble fraction and morelensin (3), bursehernin (4) from the choloroform soluble fraction. It is the first report of the occurrence of compound 5 in nature.

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.155.1-155.1
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• 2003

In the present study, the effect of DW-1350, a newly synthesized anti-osteoporotic agent, was evaluated in ovariectomized Rat. Female SD Rat mice underwent bilateral ovariectomy for prevention study that test article was administered from 2 days after ovariectomy for 6 weeks, for therapeutic study it was conducted from 6 weeks after ovariectomy for three months. (omitted)

• 대한예방의학회:학술대회논문집
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• 1995.10a
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• pp.291-292
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• 1995

• Journal of the Society of Cosmetic Scientists of Korea
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• v.12 no.1
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• pp.1-16
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• 1986

• Proceedings of the Materials Research Society of Korea Conference
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• 1998.08a
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• pp.153.1-153
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• 1998