• 대한교통학회지
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• 제22권6호
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• pp.67-77
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• 2004

본 연구는 구간검지체계의 GPS 프로브 원시데이터의 1차 기공을 위한 평균화과정에 있어 발생할 수 있는 문제점으로 이상치 문제에 대해 검토하고 있다. 이상치의 미 제거는 구간검지의 수집 및 가공 신뢰도를 저하시킬 수 있으므로 이상치에 대한 부문을 수집 주기별로 판단하여 제거해 주어야 한다. 연구에서는 이상치 제거 알고리즘으로 ARIMA 모형을 적용시켜 실시간적 신뢰구간 추정과정들을 검토해 보았다. 이러한 ARIMA 모형의 적용하기 위해 서울시 10개의 도로구간의 GPS 프로브 기반의 교통데이터에 대하여 모수 추정 기간 등을 변화시키면서 이상치 제거 개수들을 확인하였다. 모든 링크는 IMA(1,1)모형으로 모형이 식별이 되었으며, 모수 추정의 경우 추정기간이 짧아질수록 이상치 제거율이 낮아지는 즉 교통흐름에 보다 민감한 경향을 보이는 결과를 가져왔다. 이상치로 제거된 각 개별 원시 데이터의 확인이 불가하여 모형의 신뢰도 평가는 불가하여 모형의 우수성은 입증되지 못 하였으나 본 연구의 결과 수집 데이터 측면에서의이상치 제거의 모형으로서 시계열 모형이 적절하게 이용 가능할 것으로 판단된다.

• 한국통계학회:학술대회논문집
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• 한국통계학회 2004년도 학술발표논문집
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• pp.179-184
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• 2004

Statistical process control (SPC) and engineering process control (EPC) are based on different strategies for process quality improvement. SPC reduces process variability by detecting and eliminating special causes of process variation, while EPC reduces process variability by adjusting compensatory variables to keep the quality variable close to target. Recently there has been need for an integrated process control (IPC) procedure which combines the two strategies. This article considers a scheme that simultaneously applies SPC and EPC techniques to reduce the variation of a process. The process disturbance model under consideration is an IMA(1,1) model with a location shift. The EPC part of the scheme adjusts the process, while the SPC part of the scheme detects the occurrence of a special cause. For adjusting the process repeated adjustment is applied by compensating the predicted deviation from target. For detecting special causes the two kinds of exponentially weighted moving average (EWMA) control chart are applied to the observed deviations: One for detecting location shift and the other for detecting increment of variability. It was assumed that the adjustment of the process under the presence of a special cause may change any of the process parameters as well as the system gain. The effectiveness of the IPC scheme is evaluated in the context of the average cost per unit time (ACU) during the operation of the scheme. One major objective of this article is to investigate the effects of the process parameters to the ACU. Another major objective is to give a practical guide for the efficient selection of the parameters of the two EWMA control charts.

• Journal of the Korean Data and Information Science Society
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• 제24권6호
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• pp.1275-1283
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• 2013

다변량 통합공정관리의 기본절차는 잡음이 내재하는 공정에 수정조치를 취하여 공정편차벡터를 백색잡음벡터로 전환하도록 하여 공정제곱편차벡터를 최소화하게 되는 것이며, 이러한 다변량 통합공정관리의 수정활동을 하는 경우 공정에 이상원인이 발생하면 관리도를 통해 이를 탐지하고 제거하게 된다. 수정된 공정은 이상원인 발생 전에는 백색잡음이지만, 이상원인 발생 후 다양한 형태의 시계열 모형으로 변환하게 된다. 만약 수정된 공정을 탐지하여 이상원인의 신호가 발생한 경우 교정활동을 통하여 이를 제거해야 하지만, 구조적으로 교정이 불가능 하거나 교정활동의 비용이 많이 발생하는 경우에는 이상원인의 효과를 감안하여 수정활동을 재조정해야할 것이다. 이 논문에서는 공정모형으로 다변량 IMA(1,1)모형을 가정하고 다변량 통합공정관리 절차를 수행하는 경우 이상신호가 발생한 후 재수정 절차에서 필요한 모수추정을 하고자 한다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.2225-2228
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• 2012

Background: We assessed the efficacy and toxicity of ifosfamide and doxorubicin combination chemotherapy (CT) regimen retrospectively in Turkish patients with recurrent or metastatic nasopharyngeal carcinoma (NPC) previously treated with platinum-based chemotherapy. Methods: A total of thirty patients who had received cisplatin based chemotherapy/chemoradiotherapy as a primary treatment received ifosfamide 2500 $mg/m^2$ days 1-3, mesna 2500 $mg/m^2$ days 1-3, doxorubicin 60 mg/m2 day 1 (IMA), repeated every 21 days. Eligible patients had ECOG PS< 2, measurable recurrent or metastatic disease, with adequate renal, hepatic and hematologic functions. Results: Median age was 47 (min-max; 17-60). Twenty six (86.7 %) were male. Median cycles of chemotherapy for each patient were 2 (range:1-6). Twenty patients were evaluable for toxicity and response. No patient achieved complete response, with nine partial responses for a response rate of 30.0% in evaluable patients. Stable disease, and disease progression were observed in five (16.7%) and six (20.0%) patients, respectively. Clinical benefit was 46.7%. Median time to progression was 4.0 months. Six patients had neutropenic fever after IMA regimen and there were one treatment-related death due to tumor lysis syndrome in first cycle of the CT. No cardiotoxicity was observed after CT and treatments were generally well tolerated. Conclusion: Ifosfomide and doxorubicin combination is an effective regimen for patients with recurrent and metastatic NPC. For NPC patients demonstrating failure of cisplatin based regimens, this CT combination may be considered as salvage therapy.

• 대한족부족관절학회지
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• 제17권1호
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• pp.40-44
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• 2013

Purpose: To study inter- and intra-observer reliabilities of computerized measurements of the angular parameters of hallux valgus deformity, using two different kinds of software tools for angle measurement on the digital radiography. Materials and Methods: On 35 digital radiographies of standing foot anteroposterior view of hallux valgus, two observers (A, B) independently measured hallux valgus angle (HVA) and 1-2 intermetatarsal angle ($IMA_{1-2}$) twice, using two methods. In method I, an angle was determined from duplicated lines to longitudinal axes made for bisecting line on the target bones with software tool. In method II, an angle was calculated automatically and directly from bisecting lines (longitudinal axes) made on the target bones. We compared two methods using paired t-test to determine significance of differences. Inter- and intraobserver reliabilities were evaluated using the intraclass correlation coefficients (ICC). Results: There were no significant differences between measurements of method I and II for each observer (p>0.05) and intraobserver reliability were good. (ICC>0.9) Inter-observer reliability for method I and II was good of the HVA (ICCs, 0.912 and 0.905) and moderate of the $IMA_{1-2}$ (ICCs, 0.505 and 0.537). There were interobserver differences in HVA of method I and II. Conclusion: No significant difference was found statistically between measurements of method I and II. Both methods I and II would be acceptable to measure angular parameters of hallux valgus deformity.

• 대한족부족관절학회지
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• 제17권4호
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• pp.272-276
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• 2013

Purpose: Recurrence is one of the most common complications after primary correction for hallux valgus deformities. The purpose of this study was to evaluate the usefulness of Scarf osteotomy with axial decompression in the treatment of recurrent hallux valgus. Materials and Methods: From April 2006 to April 2011, 14 cases (12 patients) of recurrent hallux valgus were managed with shortening Scarf osteotomy. Preoperative and postoperative radiographs were reviewed for the measurement of the hallux valgus angle (HVA), intermetatarsal angle (IMA), and the amount of the $1^{st}$ metatarsal shortening. Clinical outcomes including the visual analogue scale (VAS), the AOFAS score, and the range of motion [ROM] of the 1st metatarsophalangeal (MTP) joint were evaluated. Results: The mean HVA decreased from 27.9 degrees to 5.2 and the mean IMA decreased from 12.9 to 3.4. The mean VAS improved from 5.3 to 0.3 and the mean AOFAS score improved from 41 to 90. The mean amount of the 1st metatarsal shortening was 3.4 mm (2-5). The mean ROM of the $1^{st}$ MTP joint improved from 22 degrees (15-35) to 68 (55-75). Conclusion: Scarf osteotomy associated with axial decompression can be a useful revision procedure for the treatment of recurrent hallux valgus deformity.

• 대한족부족관절학회지
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• 제9권1호
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• pp.64-68
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• 2005

Purpose: The purpose of this study was to evaluate the outcome of Ludloff osteotomy for treatment of hallux valgus with regard to patient satisfaction and clinical and radiological results. Materials and Methods: 43 feet of 28 patients underwent Ludloff osteotomy between January 2003 and August 2003. 21 patients (32 feet) who were available for follow up for more than one year were enrolled in this study. Average follow up period was 16 months. All patients were female and the average age was 51 years ranging 28 years to 72 years. Patient satisfaction was assessed and VAS (Visual Analogue Scale) was used for subjective outcome, AOFAS (American Orthopaedic Foot and Ankle Society) score and presence of metatarsalgia were used for clinical outcome, and hallux valgus angle and intermetatarsal angle were used for radiological outcome assessment. Results: Patient satisfaction regarding cosmesis was excellent in 6 cases, good in 21 cases, fair in 4 cases and poor in 1 case. VAS was improved from preoperative 6 points to postoperative 2 points and AOFAS score was improved from preoperative 53 points to postoperative 82 points. Metatarsalgia was observed in 18 cases preoperatively and 9 cases postoperatively. HVA and IMA were 35.8 and 15.2 degrees preoperatively, 12.5 and 6.6 degrees at 3 months follow up, and 13.2 and 7.1 degrees at last follow up respectively. At the last follow up, loss of angle of correction for HVA was 0.7 degrees and for IMA was 0.5 degrees. Conclusion: Ludloff osteotomy is an appropriate surgery of moderate to severe hallux valgus.

• Genomics & Informatics
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• 제17권4호
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• pp.37.1-37.8
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• 2019

Isolation-with-migration (IM) models have become popular for explaining population divergence in the presence of migrations. Bayesian methods are commonly used to estimate IM models, but they are limited to small data analysis or simple model inference. Recently three methods, IMa3, MIST, and AIM, resolved these limitations. Here, we describe the major problems addressed by these three software and compare differences among their inference methods, despite their use of the same standard likelihood function.

• 한국환경과학회지
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• 제7권3호
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• pp.275-280
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• 1998

In order to clarify the seasonal composition and abundance of zooplankton commuuty In Macheon Bay. the study was carried out trimonthly during the period from April 1996 to January 1997. 1 species of Cnidana. 1 species of Annelida, 2 Ima of Moiluscs.3 species of Rotifera, 4 species and 4 larspecies was Tintinnopsis beroidea In the spring, Copepodite In the summer, Tintinnopsis beroidea In the autumn and Ceratium risus In the winter. Abundance of zooplankton ranged firom 4.720 to 41,215 Inds./1 It was high In the summer (41,215 inds./l) and low In the spring 14,720 inds./l). Dominant index ranged from 0.133 (in the spring) to 0.551 (in the winter). Species diversity inden ranged from 1.114 (in the winters to 1.996 (in the spring).

• 대한족부족관절학회지
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• 제9권2호
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• pp.151-157
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• 2005

Purpose: To present our experience of distal chevron osteotomy utilizing one BOLD $screw^{(R)}$ as an alternative fixation method which has advantages over the Kirschner (K)-wire fixation. Materials and Methods: Between January 2001 and June 2003, 19 patients with a symptomatic hallux valgus deformity underwent 20 distal metatarsal chevron osteotomies with one BOLD $screw^{(R)}$ fixation. The mean age was 55.6 years with a minimum follow up period 12 months. For radiographical evaluation, hallux valgus angle (HVA) and intermetatarsal angle (IMA) were used. For clinical evaluation, we used AOFAS hallux metatarsophalangeal interphalangeal scale and overall satisfaction of the patients. Results: The AOFAS scores improved from mean 47.5 points to mean 68.1 points at postoperative 3 months and mean 86.0 points at last follow-up. The average HVA corrected from 25.3 degrees to 12.7 degrees. The IMA was corrected from 11.6 degrees to 7.6 degrees. The overall satisfaction of the patients was 85%. There was no major complication. Conclusion: We demonstrated that distal chevron osteotomy with one BOLD $screw^{(R)}$ fixation has advantages such as no additional procedure, no loss of correction, early rehabilitation, no prominent hardware and skin irritation. This method also showed excellent bone union, correction and patient satisfaction.