• 제목/요약/키워드: IL33

검색결과 2,296건 처리시간 0.031초

Allergy 비염(鼻炎)에 관(關)한 임상적(臨床的) 고찰(考察)

  • 김세일;박동일
    • 대한한방내과학회지
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    • 제19권1호
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    • pp.353-363
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    • 1998
  • This study involved 30 allergic rhinitis outpatients of section 5 of oriental medical center attached Dong Eui Uni. from April 2, 1997 to May 14, 1998. The results of this study are as follows ; 1. Men were 13 persons (43.33%) and women were 17 persons (56.67%) in sex distinction. 2. In age distinction, 1-10 years (36.67%), 11-20 (23.33%), 41-50 (16.67%), 21-30 (13.33%), 31-40 (6.67%), 61-70 (3.33%) in order of majority. 3. Acupuncture treatment of 16-20 times is 11 persons (36.67%), 26-30 times is 8 persons (26.67%), 21-25 times is 6 persons (20.00%), 11-15 times is 4 persons (13.33%), more than 31 times is 1 persons (3.33%) in order of majority. 4. The symptoms were starting to be improved apprently from more than 26 times, and it was found that the more treatments, the higher favorable turn. 5. Outbreak frequency of symptoms was rhino-cleisis, rhinorrea, ophthalmopathy, headache, sneeze, asthma, dermatitis, and sputum in order of majority. 6. Kamisunohtang of treated prescrptions is the most (80%). The effects were, rhinorrea (83.33 sneeze (66.67%) rhino-cleisis (52.17%), headache (50.00%), ophthalmopathy (20%) in order of favorable turn. 7. Favorable turn of symptoms were rhinorrea, rhino-cleisis, headache, sneeze, sputum, asthma, ophthalmopathy in order.

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상백피에 의한 MC/9 비만세포의 활성 억제 조절 연구 (Suppressive effects of Morus alba Linne Root Bark (MRAL) on activation of MC/9 mast cells)

  • 이기전;김복규;길기정
    • 대한본초학회지
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    • 제28권1호
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    • pp.33-42
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    • 2013
  • Objective : Morus alba Linne Root Bark (MRAL) is a medicinal herb in Korean Medicine, known for its anti-inflammatory and anti-allergic properties. However, its mechanisms of action and the cellular targets have not yet been found and the study was developed to investigate the allergic suppressive effect of MRAL. The purpose of this study is to investigate the allergic suppressive effects of MRAL on activation of MC/9 mast cells. Methods : Cytotoxic activity of MRAL (50, 100, 200, 400 ${\mu}g/mL$) on MC/9 mast cells measured using EZ-Cytox cell viability assay kit (WST reagent). The levels of interleukin-5 (IL-5), IL-13 and IL-4, IL-5, IL-6, IL-13 mRNA expression were measured by enzyme-linked immunosorbent assay (ELISA) and real-time PCR respectively. The expression of transcription factors such as GATA-1, GATA-2, NFAT, AP-1 and NF-${\kappa}B$ p65 DNA binding activity were measured by western blot and electrophoresis mobility shift assay (EMSA). Results : Our results indicated that MRAL (50 ${\mu}g/mL$, 100 ${\mu}g/mL$) significantly inhibited PMA/Ionomycin-induced production of IL-5 and IL-13 and the expression of IL-4, IL-5, IL-6 and IL-13 mRNA in MC/9 mast cells. Moreover, MRAL (50 ${\mu}g/mL$, 100 ${\mu}g/mL$) inhibited PMA/Ionomycin-induced GATA-1, GATA-2, NFAT-1, NFAT-2, c-Fos protein expression and NF-${\kappa}B$ p65 DNA binding activity in MC/9 mast cells. Conclusions : In conclusion, we suspect the anti-allergenic activities of MRAL, may be related to the regulation of transcription factors GATA-1, GATA-2, NFAT-1, NFAT-2, c-Fos and NF-${\kappa}B$ p65 DNA binding assay causing inhibition of Th2 cytokines IL-5 and IL-13 in mast cells.

GMT 부경 시스템 개발 계획

  • 김영수;박귀종;문일권;정나련;박병곤;여아란;천무영;육인수;이성호;박찬;김상철;김호일;양호순;이윤우
    • 한국우주과학회:학술대회논문집(한국우주과학회보)
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    • 한국우주과학회 2009년도 한국우주과학회보 제18권1호
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    • pp.33.3-33.3
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    • 2009
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