• Proceedings of the Korean Society of Sericultural Science Conference
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• 2002.04a
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• pp.51-51
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• 2002

No Abstract, See Full Text

• Journal of The Korean Society of Inherited Metabolic disease
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• v.1 no.1
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• pp.15-17
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• 2001

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2007.10a
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• pp.620-620
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• 2007

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2007.10a
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• pp.621-621
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• 2007

• 대한생식의학회:학술대회논문집
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• 2006.11a
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• pp.123-124
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• 2006

• Proceedings of the Korean Society of Sericultural Science Conference
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• 2002.10a
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• pp.105-105
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• 2002

No Abstract, See Full Text

• Proceedings of the Korean Society of Sericultural Science Conference
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• 2002.10a
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• pp.67-67
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• 2002

No Abstract, See Full Text

• Genomics & Informatics
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• v.3 no.4
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• pp.149-153
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• 2005

Asthma is an inflammatory airways disease characterized by bronchial hyperresponsiveness and airways obstruction, which results from a complex interaction of genetic and environmental factors. Interleukin (IL)-13 and IL-4 are important in IgE synthesis and allergic inflammation, therefore genes encoding IL-13 and IL-4 are candidates for predisposition to asthma. In the present study, we screened single-nucleotide polymorphisms (SNPs) in IL-13 and IL-4 and examined whether they are risk factors for asthma. We resequenced all exons and the promoter region in 12 asthma patients and 12 normal controls, and identified 18 SNPs including 2 novel SNPs. The linkage disequilibrium(LD) pattern was evaluated with 16 common SNPs, and haplotypes were also estimated within the block. Although IL-13 and IL-4 are localized within 27 kb on chromosome 5q31 and share many biological profiles, this region was partitioned into 2 blocks. One SNP and three SNPs were determined as haplotype-taggingSNPs (htSNPs) within IL-13 and IL-4 haplotype-block, respectively. No significant associations were observed between any of the SNPs or haplotypes and development of asthma in small number of Korean subjects. However, the genetic variants of IL-13 and IL-4 would provide valuable strategies for the genotyping studies in large population.

• The Bulletin of The Korean Astronomical Society
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• v.33 no.1
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• pp.74-74
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• 2008

• Bulletin of the Korean Space Science Society
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• 2005.04a
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• pp.29-29
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• 2005