• 셀메드
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• 제2권2호
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• pp.17.1-17.5
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• 2012

Ayurveda is a nearly 3000 years old traditional medical system of India. Most of the time, people turn to ayurvedic physicians in desperate conditions. Here clinical practices of Ayurveda were initially found effective in the management of migraine among few patients. Later, it was developed as an ayurvedic treatment protocol (ATP) which consists of four herbo-mineral formulations (HMF), three meals and three snacks in a day with eight hours sleep at night. ATP brought significant relief in reducing the frequency, intensity of pain and associated symptoms in the migraine patients. IHS diagnostic criteria was followed to establish the diagnosis of migraine and uniform ATP was prescribed to each patient who were primarily treated by the ayurvedic physicians at their respective clinics. Such observations were presented at appropriate international forums. In an effort to validate the above, the present study carries the details of nine migraine patients who were first diagnosed and treated for migraine by a leading headache expert at Mumbai in India and were then referred to receive ATP. A total number of nine subjects volunteered to this program. Out of those, seven subjects completed 120 days of ATP. Five subjects reported significant improvement in overall symptoms of migraine. All subjects were followed up periodically for four years. No Grade II side effects were observed in any treated case. HMF has also been proved to be safe in experimental studies. Further pharmacological and randomized controlled clinical studies are in progress at the respective departments of a premier medical institute in India.

• Annals of Clinical Neurophysiology
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• 제1권1호
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• pp.31-35
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• 1999

Dignosis of migraine is only based on the medical history, and objective methods to aid the clinical diagnosisare absent. Although transcranial Doppler ultrasonography (TCD) abnormalities in headache-free migraineurs have been reported previously, diagnostic criteria for migraine is still lacking and this may limit the practical application of TCD for migraine. We prospectively studied several abnormal TCD indices in interictal migraineurs and their sensitivity and specificity to define the optimal diagnostic criteria. Young (20 yrs$age=29.0{\pm}6.1yrs$) were compared to 69 controls (M:F=25:44, Mean $age=31.2{\pm}5.5yrs$). Elevated MFV (> 2SD)was observed in 63% of migraineurs while n 12% of control (p<0.01). High AI (>25%) or high HI (>3.0) was present in 17% of migraineurs, while 3% and none in controls (p<0.01). Sensitivity of elevated MFV, high AI, and high HI was 63%, 17%, 17% and specificity was 88%, 97%, 100%, respectively. If all these indices were combined, sensitivity and specificity reached 69% and 86%. These preliminary results suggest pathophysiological implication of vasospasm in interictal migraineurs, and TCD may be practically applicable for migraine. Optimal diagnostic criteria and therapeutic options for patients with abnormal TCD findings remain to bo determined.

• Journal of Oral Medicine and Pain
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• 제30권1호
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• pp.79-85
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• 2005

긴장성두통환자의 통증이 구강악습관과 관련이 있는지를 확인하고자 연구하였다. 일정기간 내원한 긴장성두통환자 58명 중 구강악습관(이갈이, 이악물기, 이갈이와 이악물기) 환자 20명을 실험군으로 하고, 나머지 38명을 대조군으로 하여 국제두통학회의 긴장성두통 진단기준안에 근거하여 설문조사 후 통계처리하였다. 결과는 다음과 같다. 1. 실험군과 대조군간의 성별(p=0.91) 및 나이(p=0.73)는 유의성이 없었다. 2. 통증의 종류에서 두 군 공히 둔통이 많았으며, 유의성은 없었고(p=0.69), 비둔통은 실험군이 대조군에 비해서 많았다. 3. 통증의 강도에서 두 군 공히 비심도가 많았으며, 유의성은 없었고(p=0.40), 심도는 실험군이 대조군에 비해서 많았다. 4. 통증의 양측성 유무에서 두 군 공히 편측성이 많았으며, 유의성은 없었고(p=0.52), 양측성은 실험군이 대조군에 비해서 많았다. 5. 통증의 일상생활시 악화유무에서 두 군 공히 악화가 많았으며, 유의성은 없었고(p=0.74), 악화는 실험군이 대조군에 비해서 많았다. 구강악습관이 있는 긴장성 두통환자의 통증은 구강악습관이 없는 환자에 비해서 양측성이며 심도의 비둔통이 많았고 일상생활에 의해서 더 쉽게 증가되었으나 통계적인 유의성은 없었다. 따라서, 구강악습관은 국제 두통학회에서 제시한 기준으로는 긴장성두통환자의 통증변화에 영향을 미치지 않지만, 일상생활에 의해서 더 쉽게 악화되므로 향후 저작이나 대화 등 구체적인 일상생활의 조건에 따른 변화를 확인하는 것이 필요하리라고 사료된다.