• 제목/요약/키워드: IF domain

검색결과 892건 처리시간 0.026초

Structural Studies of Peptide Binding Interaction of HCV IRES Domain IV

  • Shin, Ji Yeon;Bang, Kyeong-Mi;Song, Hyun Kyu;Kim, Nak-Kyoon
    • 한국자기공명학회논문지
    • /
    • 제21권3호
    • /
    • pp.109-113
    • /
    • 2017
  • The hepatitis C virus (HCV) internal ribosome entry site (IRES) is an RNA structure located in the 5'-UTR of the HCV RNA genome. The HCV IRES consists of four domains I, II, III, and IV, where domains II - IV are recognized by 40S ribosomal subunit and the domain III is bound to eukaryotic initiation factor 3 (eIF3) for translation initiation. Here, we have characterized the tertiary interaction between an L-/K- rich peptide and the HCV IRES domain IV. To probe the peptide binding interface in RNA, we synthesized $^{13}C$- and $^{15}N$-double labeled RNA and the binding site was identified by using the chemical shift perturbation (CSP) NMR methods. Our results showed that the peptide binds to the upper stem of the IRES domain IV, indicating that the tertiary interaction between the IRES domain IV and the peptide would disrupt the initiation of translation of HCV mRNA by blocking the start codon exposure. This study will provide an insight into the new peptide-based anti-viral drug design targeting HCV IRES RNA.

Z-영역에서 입력성형기의 설계와 민감도 해석 (Design and Sensitivity Analysis of Input Shaping Filter in the Z-domain)

  • 박운환;이재원;임병덕
    • 대한기계학회논문집A
    • /
    • 제24권7호
    • /
    • pp.1854-1862
    • /
    • 2000
  • Input shaping method is to convolute input shaper, which is sequence of impulses, with reference input command not to excite the natural frequency of system. To reduce residual vibration for the ch ange of frequency, the number of impulses should be increased. Until now, amplitudes and time interval of those has been searched from the derivative of residual vibration. However, if time interval of impulses is fixed as the half of vibration period of system, input shaper H(z) in z-domain becomes (I-pz-1)n/K in which increasing n is the mean that robustness for change of parameter is improved. Also, design of many types of input shapers in z-domain is very easy because sensitivity curve is displayed with $\mid$H(z)zn$\mid$$\times$100. In the z-domain, EI(Extra-Insensitive) input shaper could be designed without solving nonlinear simultaneous equations as design in continuous time domain. In addition to, the design possibility of input shaper for a damped system was shown.

실시간 동적 위성항법을 위한 단일차분 위치영역 Hatch 필터의 설계 (Designing Single-Differenced Position-Domain Hatch Filter for Real-Time Kinematic GNSS)

  • 이형근;;지규인
    • 한국항공우주학회지
    • /
    • 제33권7호
    • /
    • pp.59-69
    • /
    • 2005
  • 본 논문에서는 위상평활화코드 기법에 기반한 실시간 동적 차분위성항법의 효율적인 구현을 위하여 위치영역 Hatch 필터를 새로이 제안하고 그 성능을 분석하였다. 제안된 위치영역 Hatch 필터는 기존의 거리영역 Hatch를 새로운 각도에서 해석하고 이를 연장하여 유도되었다. 시뮬레이션을 통하여 Hatch 이득이 Kalman 형 이득보다 더 효율적이며 또한 위성의 출몰이 빈번한 환경에서는 위치영역 Hatch 필터가 거리영역 Hatch 필터보다 유리함을 보였다.

On the extended period of a frequency domain method to analyze transient responses

  • Chen, Kui Fu;Zhang, Qiang;Zhang, Sen Wen
    • Structural Engineering and Mechanics
    • /
    • 제31권2호
    • /
    • pp.211-223
    • /
    • 2009
  • Transient response analysis can be conducted either in the time domain, or via the frequency domain. Sometimes a frequency domain method (FDM) has advantages over a time domain method. A practical issue in the FDM is to find out an appropriate extended period, which may be affected by several factors, such as the excitation duration, the system damping, the artificial damping, the period of interest, etc. In this report, the extended period of the FDM based on the Duhamel's integral is investigated. This Duhamel's integral based FDM does not involve the unit impulse response function (UIRF) beyond the period of interest. Due to this fact, the ever-lasting UIRF can be simply set as zero beyond the period of interest to shorten the extended period. As a result, the preferred extended period is the summation of the period of interest and the excitation duration. This conclusion is validated by numerical examples. If the extended period is too short, then the front portion of the period of interest is more prone to errors than the rear portion, but the free vibration segment is free of the wraparound error.

두 조작의 합성으로서의 유리수 곱의 이론적 배경 고찰 (A Study on the Theoretical Background of the Multiplication of Rational Numbers as Composition of Operators)

  • 최근배
    • East Asian mathematical journal
    • /
    • 제33권2호
    • /
    • pp.199-216
    • /
    • 2017
  • A rational number as operator is eventually that it is considered a mapping. Depending on how selecting domain (the target of operation by rational number) and codomain (including the results of operations by rational number), it is possible to see the rational in two aspects. First, rational numbers can be deal with functions if we choose the target of operation by rational number as a number field containing rationals. On the other hand, if we choose the target of operation by rational number as integral domain $\mathbb{Z}$, then rational numbers can be regarded as partial functions on $\mathbb{Z}$. In this paper, we regard the rational numbers with a view of partial functions, we investigate the theoretical background of the relationship between the multiplication of rational numbers and the composition of rational numbers as operators.

ON INTEGRAL DOMAINS IN WHICH EVERY ASCENDING CHAIN ON PRINCIPAL IDEALS IS S-STATIONARY

  • Hamed, Ahmed;Kim, Hwankoo
    • 대한수학회보
    • /
    • 제57권5호
    • /
    • pp.1215-1229
    • /
    • 2020
  • Let D be an integral domain and S a multiplicative subset of D. An ascending chain (Ik)k∈ℕ of ideals of D is said to be S-stationary if there exist a positive integer n and an s ∈ S such that for each k ≥ n, sIk ⊆ In. As a generalization of domains satisfying ACCP (resp., ACC on ∗-ideals) we define D to satisfy S-ACCP (resp., S-ACC on ∗-ideals) if every ascending chain of principal ideals (resp., ∗-ideals) of D is S-stationary. One of main results of this paper is the Hilbert basis theorem for an integral domain satisfying S-ACCP. Also we investigate the class of such domains D and we generalize some known related results in the literature. Finally some illustrative examples regarding the introduced concepts are given.

NOTES ON CARLESON TYPE MEASURES ON BOUNDED SYMMETRIC DOMAIN

  • Choi, Ki-Seong
    • 대한수학회논문집
    • /
    • 제22권1호
    • /
    • pp.65-74
    • /
    • 2007
  • Suppose that $\mu$ is a finite positive Borel measure on bounded symmetric domain $\Omega{\subset}\mathbb{C}^n\;and\;\nu$ is the Euclidean volume measure such that $\nu(\Omega)=1$. Suppose 1 < p < $\infty$ and r > 0. In this paper, we will show that the norms $sup\{\int_\Omega{\mid}k_z(w)\mid^2d\mu(w)\;:\;z\in\Omega\}$, $sup\{\int_\Omega{\mid}h(w)\mid^pd\mu(w)/\int_\Omega{\mid}h(w)^pd\nu(w)\;:\;h{\in}L_a^p(\Omega,d\nu),\;h\neq0\}$ and $$sup\{\frac{\mu(E(z,r))}{\nu(E(z,r))}\;:\;z\in\Omega\}$$ are are all equivalent. We will also show that the inclusion mapping $ip\;:\;L_a^p(\Omega,d\nu){\rightarrow}L^p(\Omega,d\mu)$ is compact if and only if lim $w\rightarrow\partial\Omega\frac{\mu(E(w,r))}{\nu(E(w,r))}=0$.

리벳구멍을 갖는 2024 알루미늄 합금의 피로 균열 진전 동안에 발생한 음향방출 파형 특성 (Characteristics of the Acoustic Emission Waveforms from the Fatigue Crack Propagation of 2024 Aluminum Alloy with Rivet Hole)

  • 남기우;안석환
    • 한국해양공학회지
    • /
    • 제15권1호
    • /
    • pp.52-56
    • /
    • 2001
  • This study were looks at the effect of the initial cut length or stress concentration level, on the wave forms produced by crack propagation. The signals were collected, then classified visually for each type of sample. They were put into three classes according to their shapes in the time and frequency domain. Each class should domain signals which could be correlated to a certain micro-failure mechanism that occurs during the fatigue process. Classes of these signals compared, with each sample. To see if there were any classes common to the three samples. The fatigue test attempted to determine if the initial cut length has any influence on the type of signals.

  • PDF

THE OHM-RUSH CONTENT FUNCTION III: COMPLETION, GLOBALIZATION, AND POWER-CONTENT ALGEBRAS

  • Epstein, Neil;Shapiro, Jay
    • 대한수학회지
    • /
    • 제58권6호
    • /
    • pp.1311-1325
    • /
    • 2021
  • One says that a ring homomorphism R → S is Ohm-Rush if extension commutes with arbitrary intersection of ideals, or equivalently if for any element f ∈ S, there is a unique smallest ideal of R whose extension to S contains f, called the content of f. For Noetherian local rings, we analyze whether the completion map is Ohm-Rush. We show that the answer is typically 'yes' in dimension one, but 'no' in higher dimension, and in any case it coincides with the content map having good algebraic properties. We then analyze the question of when the Ohm-Rush property globalizes in faithfully flat modules and algebras over a 1-dimensional Noetherian domain, culminating both in a positive result and a counterexample. Finally, we introduce a notion that we show is strictly between the Ohm-Rush property and the weak content algebra property.

Two Extensions of a Star Operation on D to the Polynomial Ring D[X]

  • Chang, Gyu Whan;Kim, Hwankoo
    • Kyungpook Mathematical Journal
    • /
    • 제61권1호
    • /
    • pp.23-32
    • /
    • 2021
  • Let D be an integral domain with quotient field K, X an indeterminate over D, ∗ a star operation on D, and Cl∗ (D) be the ∗-class group of D. The ∗w-operation on D is a star operation defined by I∗w = {x ∈ K | xJ ⊆ I for a nonzero finitely generated ideal J of D with J∗ = D}. In this paper, we study two star operations {∗} and [∗] on D[X] defined by A{∗} = ∩P∈∗w-Max(D) ADP [X] and A[∗] = (∩P∈∗w-Max(D) AD[X]P[X]) ∩ AK[X]. Among other things, we show that Cl∗(D) ≅ Cl[∗](D[X]) if and only if D is integrally closed.