• 제목/요약/키워드: IDEAL technique

검색결과 498건 처리시간 0.028초

Cross-Flow Filtration에 의한 항생물질 생산 균사체의 분리 (Separation of Antibiotics-Producing Mycelia by Cross-Flow Filteration)

  • 정상철;윤종원
    • KSBB Journal
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    • 제4권2호
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    • pp.177-184
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    • 1989
  • 항생물질 발효액의 균사체 분리에 있어서 Modified regenerated cellulose 막을 이용한 Cross-flow filtration으로 높은 Flux를 얻을 수 있었다. 막분리시 가급적 높은 유속, 높은 온도, 특정 균사체농도(약 20% PMV)에서 높은 Flux를 보여주었으며 Fouling 정도는 균사체 농도가 높을수록 또한 유속이 낮을수록 심각한 것으로 나타났다. 발효액을 농축 분리할 때의 Flux profile은 1단계 Sublayer형성에 의한 급속감소, 2단계 평형, 3단계 Fouling에 의한 급속감소의 세 구간으로 나눌 수 있었으며 Diafiltration의 적용으로 3단계의 Flux 감소 현상을 현저히 완화시킬 수 있었다. 한편 Diafiltration에 의한 항생물질 회수시 초기부터Diafiltration하는 것보다는 특정 PMV까지 농축시킨 후 Diafiltration하는 경우에 작업시간과 여액의 Volume을 최소화 할 수 있었으며 본 실험에서는 98%의 회수율을 얻기 위해서 Di-afiltration을 시작하는 Optimum PMV는 20%였다.

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다양한 골증대술을 동반한 상악전치부 임플란트 식립 증례 (Maxillary Anterior Implant Placement with Various Bone Agumentation on Atrophic Thin Ridge : Case Reports)

  • 지영덕;조이수
    • 구강회복응용과학지
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    • 제23권2호
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    • pp.145-155
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    • 2007
  • The advent of osseointegration and advances in biomaterials and techniques have contributed to increased application of dental implants in the restoration of maxillary partial edentulous patients. Often, in these patients, soft and hard tissue defects result from a variety of causes, such as infection, trauma, and tooth loss. These create an anatomically less favorable foundation for ideal implant placement. Reconstruction of the atrophic maxillary alveolar bone through a variety of regenerative surgical procedures has become predictable; it may be necessary prior to implant placement or simultaneously at the time of implant surgery to provide a restoration with a good long-term prognosis. Regenerative procedures are used for horizontal and vertical ridge augmentation. Many different techniques exist for effective bone augmentation. The approach is largely dependent on the extent of the defect and specific procedures to be performed for the implant reconstruction. It is most appropriate to use an evidenced-based approach when a treatment plan is being developed for bone augmentation cases. The cases presented in this article clinically demonstrate the efficacy of using a autogenous block graft, guided bone regeneration, ridge split, immediated implant placement technique on the atrophic maxillary area.

쾌속조형공정 선정을 위한 지원 시스템 (A Decision Support System for the Selection of a Rapid Prototyping Process)

  • 변홍석;이관행
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 2003년도 춘계학술대회 논문집
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    • pp.5-8
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    • 2003
  • This paper presents a methodology to be able to select an appropriate RP system that suits the end use of a part. Evaluation factors used in process selection include major attributes such as accuracy, roughness, strength, elongation, part cost and build time that greatly affect the performance of RP systems. Crisp values such as accuracy and surface roughness are obtained with a new test part developed. The test part is designed with conjoint analysis to reflect users' preference. The part cost and build time that have approximate ranges due to cost and many variable parameters are presented by linguistic values that can be described with triangular fuzzy numbers. Based on the evaluation values obtained, an appropriate RP process for a specific part application is selected by using the modified TOPSIS(Technique of Order Preference by Similarity to Ideal Solution) method. It uses crisp data as well as linguistic variables, and each weight on the alternatives is assigned by using pair-wise comparison matrix. The ranking order helps the decision making of the selection of RP systems.

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Deformation behaviours of SS304 tubes in pulsating hydroforming processes

  • Yang, Lianfa;Wang, Ninghua;He, Yulin
    • Structural Engineering and Mechanics
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    • 제60권1호
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    • pp.91-110
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    • 2016
  • Tube hydroforming (THF) under pulsating hydraulic pressures is a novel technique that applies pulsating hydraulic pressures that are periodically increased to deform tubular materials. The deformation behaviours of tubes in pulsating THF may differ compared to those in conventional non-pulsating THF due to the pulsating hydraulic pressures. The equivalent stress-strain relationship of metal materials is an ideal way to describe the deformation behaviours of the materials in plastic deformation. In this paper, the equivalent stress-strain relationships of SS304 tubes in pulsating hydroforming are determined based on experiments and simulation of free hydraulic bulging (FHB), and compared with those of SS304 tubes in non-pulsating THF and uniaxial tensile tests (UTT). The effect of the pulsation parameters, including amplitude and frequency, on the equivalent stress-strain relationships is investigated to reveal the plastic deformation behaviours of tubes in pulsating hydroforming. The results show that the deformation behaviours of tubes in pulsating hydroforming can be well described by the equivalent stress-stain relationship obtained by the proposed method. The amplitude and frequency of pulsating hydraulic pressure have distinct effects on the equivalent stress-strain relationships-the equivalent stress becomes augmented and the formability is enhanced with the increase of the pulsation amplitude and frequency.

Multi-objective optimization design for the multi-bubble pressure cabin in BWB underwater glider

  • He, Yanru;Song, Baowei;Dong, Huachao
    • International Journal of Naval Architecture and Ocean Engineering
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    • 제10권4호
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    • pp.439-449
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    • 2018
  • In this paper, multi-objective optimization of a multi-bubble pressure cabin in the underwater glider with Blended-Wing-Body (BWB) is carried out using Kriging and the Non-dominated Sorting Genetic Algorithm (NSGA-II). Two objective functions are considered: buoyancy-weight ratio and internal volume. Multi-bubble pressure cabin has a strong compressive capacity, and makes full use of the fuselage space. Parametric modeling of the multi-bubble pressure cabin structure is automatic generated using UG secondary development. Finite Element Analysis (FEA) is employed to study the structural performance using the commercial software ANSYS. The weight of the primary structure is determined from the volume of the Finite Element Structure (FES). The stress limit is taken into account as the constraint condition. Finally, Technique for Ordering Preferences by Similarity to Ideal Solution (TOPSIS) method is used to find some trade-off optimum design points from all non-dominated optimum design points represented by the Pareto fronts. The best solution is compared with the initial design results to prove the efficiency and applicability of this optimization method.

소폐동맥 내피세포를 이용한 인조혈액접촉표면의 혈액 접합성 (Blood Compatibility of Artificial Blood-Contacting Surface Seeded with Cultured Bovine Endothelial Cells)

  • 김원곤;곽영태;유세영
    • Journal of Chest Surgery
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    • 제26권2호
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    • pp.80-85
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    • 1993
  • Synthetic and biosynthetic vascular grafts of small diameter have long been considered to be prone to thrombosis, ultimately leading to the complete graft occlusion. Endothelial cell seeding onto synthetic blood-contacting surfaces has been suggested to be an ideal means to solve this problem. This study described a culture method of bovine endothelial cells and evaluated blood-compatibility and seeding efficiency of cultured endothelial cells. Bovine pulmonary artery endothelial cells were harvested enzymatically and grown to confluence on polystyrene culture flask surfaces using established techniques. The identification of endothelial cells was made through the demonstration of expression of factor VIII R:Ag by immunofluorescent technique. To quantitate the effect of improvement in blood-compatibility of viable endothelial cells, endothelial monolayers were exposed to blood containing $\^$111/In-oxine labeled platelets. Viable endothelial monolayers retained less labeled platelets than control surfaces. The Indium-labeled endothelial cells were seeded onto three different blood-contacting surfaces of Dacron vascular graft immobilized in specially equipped wells and incubated for specific time intervals (t=15, 30, 60, 120 minutes). Longer incubation times showed improved cell adherence in collagen-coated and fibrin-coated Dacron vascular graft groups. However in untreated Dacron grafts, no direct relationship was observed between incubation time and endothelial cell seeding efficiency. This may be due to leakage of endothelial cells through porosity of Dacron grafts in this in-vitro experimental condition.

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On-Film Formation of Nanowires for High-efficiency Thermoelectric Devices

  • Ham, Jin-Hee;Shim, Woo-Young;Lee, Seung-Hyun;Voorhees, Peter W.;Lee, Woo-Young
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2009년도 춘계학술대회 논문집
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    • pp.17-17
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    • 2009
  • We report the invention of a direct growth method termed On-Film Formation of Nanowire (OFF-ON) for making high-quality single-crystal nanowires, i.e. Bi and $Bi_2Te_3$, without the use of conventional templates, catalysts, or starting materials. We have used the OFF-ON technique to grow single crystal semi-metallic Bi and compound semiconductor $Bi_2Te_3$ nanowires from sputtered Bi and BiTe films after thermal annealing, respectively. The mechanism for nanowire growth is stress-induced mass flow along grain boundaries in the polycrystalline films. OFF-ON is a simple but powerful method for growing perfect single-crystal semi-metallic and compound semiconductor nanowires of high aspect ratio with high crystallinity that distinguishes it from other competitive growth approaches that have been developed to date. Our results suggest that Bi and $Bi_2Te_3$ nanowires grown by OFF-ON can be an ideal material system for exploring their unique thermoelectric properties due to their high-quality single crystalline and high conductivity, which have consequence and relevance for high-efficiency thermoelectric devices.

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Application of meta-model based parameter identification of a seismically retrofitted reinforced concrete building

  • Yu, Eunjong
    • Computers and Concrete
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    • 제21권4호
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    • pp.441-449
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    • 2018
  • FE models for complex or large-scaled structures that need detailed modeling of structural components are usually constructed using commercial analysis softwares. Updating of such FE model by conventional sensitivity-based methods is difficult since repeated computation for perturbed parameters and manual calculations are needed to obtain sensitivity matrix in each iteration. In this study, an FE model updating procedure avoiding such difficulties by using response surface (RS) method and a Pareto-based multiobjective optimization (MOO) was formulated and applied to FE models constructed with a commercial analysis package. The test building is a low-rise reinforced concrete building that has been seismically retrofitted. Dynamic properties of the building were extracted from vibration tests performed before and after the seismic retrofits, respectively. The elastic modulus of concrete and masonry, and spring constants for the expansion joint were updated. Two RS functions representing the errors in the natural frequencies and mode shape, respectively, were obtained and used as the objective functions for MOO. Among the Pareto solutions, the best compromise solution was determined using the TOPSIS (Technique for Order of Preference by Similarity to Ideal Solution) procedure. A similar task was performed for retrofitted building by taking the updating parameters as the stiffness of modified or added members. Obtained parameters of the existing building were reasonably comparable with the current code provisions. However, the stiffness of added concrete shear walls and steel section jacketed members were considerably lower than expectation. Such low values are seemingly because the bond between new and existing concrete was not as good as the monolithically casted members, even though they were connected by the anchoring bars.

Formula to identify the Influence of steel fibres on the mechanical properties of HPC

  • Philip, Nivin;Anil, Sarah
    • Computers and Concrete
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    • 제25권5호
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    • pp.479-484
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    • 2020
  • This work performed to analyses the impact of hooked end steel fibres on the mechanical properties of high performance concrete. The mechanical properties considered incorporate compressive strength, split tensile strength and flexural strength. Taking in to thought parameters, such as, volume fraction of fibres, fibre aspect ratio and grade of concrete, a logical strategy called Taguchi technique was utilized to discover the ideal blend of factors. L9 Orthogonal Array (OA) of Taguchi network comprising of three variables and three dimensions is utilized in this work. The evaluations of concrete considered were M60, M80 and M100. M60 contained 15% of metakaolin as bond swap though for M80 it was 5% of metakaolin and for M100 it was 10% metakaolin and 10% of silica smolder. The volume portion of fiber was fluctuated by 0.5%; 1% and 1.5% and the viewpoints proportions considered were 50, 60 and 80. The test outcomes demonstrate that incorporation of steel fibres enhance significantly the the strength characteristics of concrete, predominantly the splitting tensile strength and flexural strength. In light of relapse investigation of the test information scientific models were produced for compressive strength, split tensile strength and flexural strength of the steel fibre-reinforced high performance concrete.

An Exploratory Research on the Implementation of Corporate Social Responsibility (CSR) in the Real Estate Sector of UAE: A Dyadic Perspective

  • THOMAS, Suja Sarah;POTLURI, Rajasekhara Mouly
    • 유통과학연구
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    • 제18권10호
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    • pp.101-110
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    • 2020
  • Purpose: The study investigates the implementation of corporate social responsibility (CSR) in the real estate sector of the UAE by collecting the opinions of both the real estate companies and different tenants on the execution of CSR. Research design, data, and methodology: Using a sample of 300 different types of UAE real estate consumers and twenty real estate firms, the researchers collected the opinions of targeted subjects by administering two types of questionnaires. The Cronbach's Alpha and the Kaiser-Meyer-Olkin (KMO) tests were employed to check the internal consistency and validity of the questionnaires. The selected hypotheses were tested using the Kruskal-Wallis (K-W) hypothesis testing technique. Results: The findings revealed that all types of UAE real estate consumers expressed their discontentment over the implementation of socially responsible actions by the real estate companies. Whereas UAE real estate companies expressed their confidence in the ideal implementation of social actions towards all stakeholders in general and tenants. Conclusion: Even though more than 50 percent of realty customers are dissatisfied with the company's implementation of CSR, a little over 54.80 percent are willing to recommend the company to their family and friends. Implications have been provided for UAE real estate companies who wish to promote their business to all categories of UAE real estate consumers successfully.