• Microbiology and Biotechnology Letters
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• v.40 no.4
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• pp.409-413
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• 2012

Indolicidin (ID) is a 13-residue Trp-rich antimicrobial peptide (AMP) isolated from bovine neutrophils. In addition to having a high antimicrobial potency, it is also toxic to mammalian cells. To develop novel ID-derived AMPs with shorter lengths and enhanced prokaryotic selectivities (meaning potent antimicrobial activity against bacterial cells without toxicity against mammalian cells) over the parental ID, several ID analogs were designed and synthesized. Finally, 10-residue ID analogs (SI, SI-PA, SI-WF and SI-WL) with much higher prokaryotic selectivity than the parental ID were developed. Our results suggest that the hydrophobic and aromatic amino acids at the central position of the analog SI with the highest prokaryotic selectivity are important for potent antimicrobial activity, but two Pro residues do not affect antimicrobial activity. The order of prokaryotic selectivity for ID and its designed analogs was SI > SI-PA > SI-WF > SI-WL > ID > SI-WA. Taken together, our designed short ID analogs could be developed as therapeutic agents for treating bacterial infections.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.9 no.4
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• pp.43-51
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• 2010

In this paper, we studied line coding technology tendency for high speed data communication at LED-ID (Identification) communication system in indoor environment. A LED-ID technology is a communication using visible ray (RGB) that come out in LED device. It is energy curtailment effect and possible in ubiquitous network service applications. The LED-ID system has the above advantages about that the communication throughout the whole room is enabled by high power lighting and lighting equipment with white colored LED which are easy to install and have good outward appearance. Therefore, the transmission by light waves is more suitable for wireless networks than by radio waves. We compared with the NRZ, AMI, 4B5B, HDB3, 8B10B line coding for efficient in error detection and serves data transmission of high speed.

• Toxicological Research
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• v.18 no.4
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• pp.375-384
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• 2002

Repeated-dose toxicity of hyrubicin ID6105, a novel anthrarycline anticancer agent, was investigated in Sprague-Dawley rats. ID6105 was injected intravenously to rats at dose levels of 0.04, 0.2 or 1.0 mg/kg/day for 4 week. As a result, there were no dose-related mortality and specific clinical signs of all animals treated with the drug. However body weight gain of both male and female rats treated with a high dose (l.0 mg/kg/day) of ID6105 significantly decreased compared to control. Interestingly, the numbers of RBC and platelets, and concentration of hemoglobin remarkably increased, while protein synthesis was suppressed, which may be related to the atrophy of spleen, thymus and liver. Moreover there were severe lymphocytic depletion in spleen and thymus as well as decrease in the number of hematopoietic cells in bone marrow. Also, degeneration of cardiac muscles and testicular germinal epithelia were observed. Taken together, it is suggested that Long-term administration of ID6105 at high doses over 0.2 mg/kg/day might cause hematopoietic and male reproductive system injuries, in addition to hepatic dysfunction.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.41 no.8
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• pp.79-85
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• 2004

In this paper, the RF-ID system for ubiquitous tagging applications has been designed, fabricated and analysed. The RF-ID System consists of passive RF-ID Tag and Reader. The passive RF-ID tag consists of rectifier using zero-bias schottky diode which converts RF power into DC power, ID chip, ASK modulator using bipolar transistor and slot loop antenna. We suggest an ASK undulation method using a bipolar transistor to compensate the disadvantage of the conventional PIN diode, which needs large current Also, the slot loop antenna with wider bandwidth than that of the conventional patch antenna is suggested The RF-ID reader consist of patch array antenna, Tx/Rx part and ASK demodulator. We have designed the RF-ID System using EM and circuit simulation tools. According to the measured results, The power level of modulation signal at 1 m from passive RF-ID Tag is -46.76 dBm and frequency of it is 57.2 KHz. The transmitting power of RF-ID reader was 500 mW

• Journal of the Korea Institute of Information Security & Cryptology
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• v.4 no.2
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• pp.90-118
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• 1994

본 논문에서는 certificatoin-based 방식이 아닌 id-based방식이면서도 사용자가 자신의 비밀키를 선택할 수 있는 역설적인 id-based 방식을 제안한다. 제안한 방식은 Girault가 제안한 self-certified공개키 개념을 id-based방식에 적용한 것이다. 제안한 방식의 안전성은 고차잉여류 문제와 이산대수 문네에 기반을 두고 있다.

• Convergence Security Journal
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• v.12 no.4
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• pp.57-69
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• 2012

C4ISR system is an important tool for military operational command and control. Therefore, it is frequently exposed to the cyber-terror attempt to paralyze the military command and control system. Generally, the information system uses IDS and firewall as major security computing tools. C4ISR system also uses them as major measures for the information protection. But the usefulness of IDS is reduced due to the frequent false-positives and false-negatives if the behavioral patterns are modified or new behavioral patterns appear. This paper presents new IDS structure which can create modified attack patterns and unexpected attack patterns automatically during IDS probing process. The proposed IDS structure is expected to enhance the information protection capability of the C4ISR system by reducing false-positives and false-negatives through the creation and verification of new attack patterns.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.55 no.4
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• pp.167-175
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• 2006

This paper presents a method to segment semiconductor wafer ID on poor quality images. The method is based on multiple templates and normalized gray-level correlation (NGC) method. If the lighting condition is not so good and hence, we can not control the image quality, target image to be inspected presents poor quality ID and it is not easy to identify and then recognize the ID characters. Conventional several method to segment the interesting ID regions fails on the bad quality images. In this paper, we propose a multiple template method, which uses combinational relation of multiple templates from model templates to match several characters of the inspection images. To find out the optimal solution of multiple template model in ID regions, we introduce newly-developed snake algorithm. Experimental results using images from real FA environment are presented.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.25 no.4
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• pp.411-417
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• 2014

In this paper, we propose an efficient OFDM(Orthogonal Frequency Division Multiplexing) frame synchronization scheme for LED-ID(Identification) systems. A frame synchronization is an essential procedure for normal operations of OFDM systems. Bernoulli-Gaussian noise is considered in LED-ID systems' environments. In order to enhance the OFDM frame synchronization performance, we add a ROGS(Repeated Orthogonal Gold Sequence) to OFDM signals in the time domain. The power level of a ROGS does not affect a normal operation of the LED-ID systems. Frame synchronization can be achieved successfully over LED-ID channels interfered by impulsive noise owing to good auto and cross-correlation properties of the ROGS.

• Journal of IKEEE
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• v.19 no.4
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• pp.610-616
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• 2015

In this paper, an electronic ID system satisfying security requirements of authentication certificate was designed using fingerprint recognition. The proposed electronic ID system generates a digital signature with forgery prevention, confidentiality, content integrity, and personal identification (=non-repudiation) using fingerprint information, and also encrypts, sends, and verify it. The proposed electronic ID system exploits fingerprint instead of user password, so it avoids leakage and hijacking. And it provides same legal force as conventional authentication certificate. The proposed electronic ID consists of 4 modules, i.e. HSM device, verification server, CA server, and RA client. Prototypes of all modules are designed and verified to have correct operation.

• Archives of Pharmacal Research
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• v.28 no.4
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• pp.476-482
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• 2005

We investigated the pharmacokinetics of 11-hydroxyaclacinomycin X (ID-6105), a novel anthracycline, after intravenous (i.v.) bolus administration at a multiple dose every 24 h for 5 days in rats. To analyze ID-6105 levels in biological samples, we used an HPLC-based method which was validated in a pharmacokinetic study by suitable criteria. The concentrations of ID-6105 after the multiple administration for 5 days were not significantly different from the results after the single administration. The $t_{1/2\alpha}, t_{l/2\beta}, V_{dss}, and CL_{t}$ after the multiple administration were not significantly different from the values after the single administration. Moreover, the concentrations of ID-6105 1 min at day 1-5 after i.v. bolus multiple administration did not show the significant difference. Of the various tissues, ID-6105 mainly distributed to the kidney, lung, spleen, adrenal gland, and liver after i.v. bolus multiple administration. ID-6105 concentrations in the kidney or lung 2 h after i.v. bolus administration were comparable to the plasma concentration shortly after i.v. bolus administration. However, the ID-6105 concentrations in various tissues 48 h after i.v. bolus administration decreased to low levels. ID-6105 was excreted largely in the bile after i.v. bolus multiple administration at the dose of 3 mg/kg. The amounts of ID-6105 found in the bile by 12 h or in the urine by 48 h after the administration were calculated to be $14.1\% or 4.55\%$ of the initial dose, respectively, indicating that ID-6105 is mostly excreted in the bile. In conclusion, ID-6105 was rapidly cleared from the blood and transferred to tissues, suggesting that ID-6105 might not be accumulated in the blood following i.v. bolus multiple dosages of 3 mg/kg every 24 h for 5 days. By 48 h after i.v. bolus administration, ID-6105 concentrations in various tissues had decreased to very low levels. The majority of ID-6105 appears to be excreted in the bile.