• 미생물학회지
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• 제38권3호
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• pp.198-204
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• 2002

폴리오 바이러스는 전형적인 장관계 바이러스로 마비, 무균성 수막염, 뇌염 등을 유발한다. 폴리오 바이러스는 분변-구강 경로를 통해 전파되며, 오염된 물을 음용수로 사용할 시 공중 보건에 문제가 될 수 있으므로 먹는 물에서 폴리오 바이러스를 검출하는 것은 중요하다. 감염성이 있는 바이 러스와 불활성화(열처리와 자외선 처리)시킨 바이러스를 세포배양법, 역전사 중합효소 연쇄반응법(reverse transcription-polymerase chain reaction: RT-PCR)그리고 세포배양-중합효소 연쇄반응 통합법(integrated cell culture-PCR: ICC-PCR)으로 검출 실험을 했다. 감염성이 있는 폴리오 바이러스는 세 가지 방법으로 모두 검출이 되었으며, 이 중에서 바이러스를 검출하는데 ICC-PCR 방법이 가장 민감했다. 세포배양법은 적은 수의 바이러스를 검출하는데 약 2주의 긴 시간이 걸렸다. 열처리나 자외선 처리로 불활성화된 바이 러스는 세포배양과 ICC-PCR방법으로는 검출이 되지 않았다. 자외선 처리한 바이러스는 RT-PCR 방법으로 검출되지 않았으나 열처리한 바이러스는 검출되었다. RT-PCR 방법은 감염성 바이러스뿐 아니라 불활성화된 바이러스도 검출할 수 있으므로 감염성이 있는지 없는지를 구분할 수 없는 단점이 있다. 이와 같은 결과는 감염성 있는 바이러스를 가장 민감하고 효과적으로 검출하는 방법이 ICC-PCR 방법이라는 것을 제시하여 준다.

• 대한통합의학회지
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• 제10권4호
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• pp.137-143
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• 2022

Purpose : The purpose of this study was to evaluate the reliability analysis of the deep tendon reflex by using electromyography (EMG). Methods : The study was tested on 30 volunteers who are women in their 20s. Using an electronic reflective hammer of EMG, deep tendon reflex was measured on all subjects with the participation of three trained physical therapists as raters. First, the subjects were comfortably seated on a table with their knees bent at 90 °. The three raters tapped the electric hammer at intervals of 10 seconds to avoid habituation until a total of 10 compound muscle action potential records were collected. Intraclass correlation coefficients (ICCs) were calculated to assess the inter-rater reliability of the deep tendon reflex with the use of EMG. The items of analysis included amplitude (mV), latency (ms), duration (ms), and area (mV × ms) of the compound evoked potentials. Results : Based on the average records of 10 compound muscle action potential, excellent reliability (ICC: .912) was achieved in terms of area, and there was good reliability in terms of latency (ICC: .795) and duration (ICC: .800). In the shortest latency of the compound muscle action potential, good reliability was achieved in terms of amplitude (ICC: .865), duration (ICC: .781), and area (ICC: .832). In the amplitude of peak-to-peak of compound muscle action potential, excellent reliability was recorded in terms of amplitude (ICC: .924), and good reliability was recorded in terms of duration (ICC: .801) and area (ICC: .874). Conclusion : The findings in this study indicate that electromyography via an electric hammer is a reliable method of assessing and measuring deep tendon reflexes. Especially, it may be an excellent gauge in the area of average values of the compound muscle action potentials and the amplitude of peak-to-peak of compound muscle action potentials.

• 국제학술발표논문집
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• The 8th International Conference on Construction Engineering and Project Management
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• pp.257-264
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• 2020

Objective: To investigate test-retest reliability and responsiveness of Equivital Lifemonitor and photoplethysmography based wristwatch tools in assessing physiological parameters during a simulated fatigue task. Methods: Ten university students (Mean age, 30.6 ± 1.7 years) participated in this pilot study. Participants were asked to perform a 30-minute of a simulated fatigue task in an experimental setup in a lab. The physiological parameters (e.g., heart rate, heart rate variability, respiratory rate, electrodermal activity, and skin temperature) were measured at baseline and immediately after the fatigue task. An intraclass correlation coefficient (ICC2,1) was used to evaluate the test-retest reliability of each tool in assessing physiological measures. In addition, the responsiveness of each tool to measure changes from baseline to posttest was calculated using a standardized response mean. Results: The Equivital Lifemonitor has shown good to excellent test-retest reliability for the assessment of heart rate (ICC, 0.97), heart rate variability (ICC, 0.86), respiratory rate (ICC, 0.77), and local skin temperature (ICC, 0.76). However, photoplethysmography based wristwatch showed moderate to good test-retest reliability for the assessment of heart rate (ICC, 0.71), heart rate variability (ICC, 0.73), electrodermal activity (ICC, 0.80), and skin temperature (ICC, 0.72). A large standardized response mean (>0.8) indicates that both tools can capture the changes in heart rate, heart rate variability, respiratory rate, skin temperature, and electrodermal activity after a 30-minute of fatigue task. Conclusions: The Equivital Lifemonitor and photoplethysmography based wristwatch devices are reliable in measuring physiological parameters after the fatigue task. Additionally, both devices can capture the fatigue response after a simulated construction task. Future field studies with a larger sample should investigate the sensitivity and validity of these tools in measuring physiological parameters for fatigue assessment at construction sites.

• 대한한의학방제학회지
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• 제32권1호
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• pp.29-37
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• 2024

Objectives : The purpose of this study was to examine the effects of insurance herbal medicines on colonic interstitial Cells of Cajal (ICC) in mice. Methods : Among the insurance herbal medicines, we chose Gamisoyo-san (GSS), Banhasasim-tang (BHSST) and Bojungikki-tang (BGIKT). We made the ICC culture in large intestine in mice and used the electrophysiological method to record pacemaker potentials. Also we used MTT assay to check cell viability and examined the ICC protein expression by western blot. Results : 1. GSS (1-10 mg/ml) induced the pacemaker potential depolarization and decreased frequency with concentration-dependent manners in colonic ICC. EC50 is 2.99 mg/ml. BHSST (1-10 mg/ml) induced the pacemaker potential depolarization and decreased frequency with concentration-dependent manners in colonic ICC. EC50 is 2.76 mg/ml. BGIKT (1-10 mg/ml) induced the pacemaker potential depolarization and decreased frequency with concentration-dependent manners in colonic ICC. EC50 is 4.49 mg/ml. 2. GSS, BHSST and BGIKT had no effects on cell viability in colonic ICC. 3. GSS and BGIKT increased the Anoctamin-1 (ANO1) protein expression and BHSST increased the transient receptor potential melastatin-subfamily member 7 (TRPM7) protein expression in colonic ICC. Conclusions : These results suggest that GSS, BHSST, and BGIKT have shown the potential to regulate gastrointestinal (GI) motility by regulating colonic ICC and may show the potential to treat colon-derived GI diseases such as irritable bowel syndrome (IBS).

• 항공우주정책ㆍ법학회지
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• 제15권
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• pp.40-66
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• 2002

The purpose of this paper is to investigate the legal controㅣ, by using the International Criminal Court(ICC) that will enter into force to the most serious crimes of concern to the international community as a whole, and regulates the jurisdiction with respect to the following crimes: (a) The crime of genocide; (b) Crimes against humanity; (c) War crimes; Cd) The crime of aggression. However, the existing ICC Statute excludes (e) Crimes, established under or pursuant to the treaty, which was regulated by the ICC draft statute that the International Law Commission(ILC) examined and submitted to the UN General Assembly in 1994, and which contained aircraft terrorism such as hijacking in the Hague Convention of 1970 or sabotage in the Montreal Convention of 1971 in Annex of ILC draft. Therefore, this paper examines the legal character of aircraft terrorism as one of the most serious crimes of concern to the international community as a whole, and suggests two kinds of legislative comments for the amendment of the ICC Statute including aircraft terrorism as an object of the jurisdiction of the Court, for suppressing aircraft terrorism in advance and ensuring equitable penalty by ICC system.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2013년도 추계학술대회
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• pp.898-899
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• 2013

본 연구에서 사용되는 컨테이너 보안 장치의 전도성 대역에서 전도성 노이즈가 방출되는 현상을 전자파 저감 기술을 활용하여 측정 주파수 0.204MHz에서 40.3dBuV로 저감하여 컨테이너 보안장치의 전자파 노이즈억제기술개발을 확보한 기술 내용을 기재하였다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2000년도 추계종합학술대회 논문집(4)
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• pp.259-262
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• 2000

One of the major factors determining the printing quality of a color printer is the color matching that is performed inside the printer driver In this paper, the mini driver for the color printer is built using the Microsoft 98DDK. Also, the ICC profile proposed as the standard for the color management system is generated. The color matching capability of the mini driver with the ICC profile is examined and compared with that of the commercial printer driver.

• 한국문헌정보학회지
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• 제26권
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• pp.3-33
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• 1994

The author have devised the main table of International Centesimal Classification(ICC). This is the second study of ICC. And so, this study intends to devise a new and reasonable form divisions for the ICC. This study analyses the 'standard subdivisions' of DDC and the 'general form divisions' of UDC and LCC, to investigate the problems included among them. And then, it devises the three tables of 'Internal form divisions, External form divisions, and Special form divisions' in two digit of arabic numerals.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2002년도 추계학술발표논문집 (상)
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• pp.731-734
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• 2002

컴퓨터 주변 장치를 통해 다루어지는 디지털 영상의 컬러 화질 개선을 위하여 행해지는 영상의 컬러 정보 변환에 산업 표준으로 그 사용이 점차 확대되어 가고 있는 ICC 디바이스 프로파일 표준 규격에 대하여 초기 버전인 3.0 에서 최신 버전인 4.0 까지의 개정안에 대해 알아보고, 한국전자통신연구원에서 개발한 ICC 디바이스 프로파일을 이용한 컬러운영시스템을 이용한 영상 변환에 대하여 알아본다.

• 대한한의학방제학회지
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• 제30권2호
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• pp.37-44
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• 2022

Objectives : The purpose of this study was to examine the effects of Alisma canaliculatum Extract (ACE) on pacemaker potentials of small and large intestinal interstitial Cells of Cajal (ICC) in mice. Methods : We used enzymatic digestions to dissociate the ICC in the small and large intestine in mice. The whole-cell patch-clamp method was used to record pacemaker potentials in ICC. Results : 1. The ICC generated the pacemaker potentials in small intestine in mice. ACE (0.1-1mg/ml) induced membrane depolarization and decreased frequency with concentration-dependent manners. 2. Pretreatment with a Ca²⁺ free solution, Na⁺ 5 mM solution or 2-APB, a nonselective cation channel blocker, stopped the small intestinal ICC pacemaker potentials. In the case of Ca²⁺-free solution, Na⁺ 5 mM solution or 2-APB, ACE had no effects on the membrane depolarizations in small intestinal ICC. 3. The ICC generated the pacemaker potentials in large intestine in mice. Membrane depolarization appears regularly in the small intestine, but irregularly in the large intestine. ACE induced membrane depolarization (0.1-1mg/ml) and increased frequency (0.1-0.5mg/ml). 4. Pretreatment with a Ca²⁺ free solution, Na⁺ 5 mM solution or 2-APB, stopped the large intestinal ICC pacemaker potentials. In the case of Ca²⁺-free solution, Na⁺ 5 mM solution or 2-APB, ACE depolarized the membrane depolarizations in large intestinal ICC. 5. In mice, intestinal transit rate (ITR) values were dose-dependently decreased by the intragastric administration of ACE. Conclusions : These results suggest that ACE can regulate the pacemaker activity of ICC and the reaction by ACE is different from the small and large intestinal ICC, and the control of the intestinal motion by ACE may be caused by many complex processes.