• Nutrition Research and Practice
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• 제15권4호
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• pp.411-430
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• 2021

Irritable bowel syndrome (IBS) is a frequently diagnosed gastrointestinal (GI) disorder characterized by recurrent abdominal pain, bloating, and changes in the stool form or frequency without any structural changes and overt inflammation. It is not a life-threatening condition but causes a considerable level of discomfort and distress. Among the many pathophysiologic factors, such as altered GI motility, visceral hypersensitivity, and low-grade mucosal inflammation, as well as other immunologic, psychologic, and genetic factors, gut microbiota imbalance (dysbiosis), which is frequently found in IBS, has been highlighted as an etiology of IBS. Dysbiosis may affect gut mucosal homeostasis, immune function, metabolic regulation, and even visceral motor function. As diet is shown to play a fundamental role in the gut microbiota profile, this review discusses the influence of diet on IBS occurring through the modulation of gut microbiota. Based on previous studies, it appears that dietary modulation of the gut microbiota may be effective for the alleviation of IBS symptoms and, also an effective IBS management strategy based on the underlying mechanism; especially because, IBS currently has no specific treatment owing to its uncertain etiology.

• 대한한방소아과학회지
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• 제32권3호
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• pp.119-130
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• 2018

Objectives The purpose of this study is to review the effectiveness of acupuncture treatment in irritable bowel syndrome (IBS). Methods We reviewed 8 randomized controlled trials (RCT) of acupuncture treatment in IBS which were published from 2008 to 2018 in PubMed. The acupoints, methods of assessment, treatment, results and adverse events were analyzed. Results There were 8 RCT of acupuncture treatment in IBS. The most commonly used acupoints were 天樞 (ST25), and 上巨虛 (ST37). Frequently used assessments in IBS were Bristol scale, visual analogue scale, IBS-symptom severity score, quality of life, and symptom scale. 3 out of 8 studies, the acupuncture treatment group showed significant effectiveness than that of the control group. Conclusions All of the studies have not shown that the acupuncture treatment was effective in relieving IBS symptoms. More clinical studies are needed to prove the effectiveness of the acupuncture treatment in IBS.

• 성인간호학회지
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• 제20권5호
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• pp.685-696
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• 2008

Purpose: This study was performed to examine the frequency of irritable bowel syndrome(IBS), perceived stress, and mental health among community-dwelling women. Methods: This study conducted a survey to collect data on 869 women in Seoul and Gyeonggi-do. The measurements included the Rome III criteria(to diagnose IBS), the Global Assessment Recent Stress(GARS scale to evaluate perceived stress), and symptom check list 90R(SCL-90R to evaluate psychological distress). Data were analyzed using SPSS 15.0 program by frequency, $x^2$-tests, t-test, and analysis of variance(ANOVA). Results: The frequency of IBS in women was 15.1%. Eighty-six women(65.6%) had mixed constipation and diarrhea subtype of IBS. Compared to the women without IBS, those with IBS reported significantly higher scores on GARS, all subscales of GARS, SCL-90R, all subscales of SCL-90R, and the global severity index(GSI). No significant differences were observed among stress, mental health, and the IBS subtypes. Conclusion: Nursing interventions targeting women with IBS should be developed in order to reduce the associated stress and psychological distress.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 1995년도 VTS and IBS 95 The Korean Institute of Navigation 1995년도
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• pp.125-152
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• 1995

An Integrated Bridge System (IBS) is not an officially defined term, but a concept of which integrates on a consol at bridge the primary functions of stand-alone navigational aids and communication instruments or of stand-alone units which are integrated i.e. ARPA ECDIS It aims to enable officers on navigational watch to perform their duty without impairing proper lookout. IBS has been taking shape through a rapid development of navigation and communication systems in relation with bridge configuration bridge work station and one man bridge operation system. IBS related matters have been considered for years and is on the agenda of the International Maritime Organization(IMO) for its technical details and safety aspect of possible one-man watchkeeping at night. However IMO has made it clear that human element should be the key factor in considering IBS and single watchkeeping issue. In the development of IBS ergonomic element and human psychological aspect have been more emphasized than technical requirements. This paper refers to documents presented to the IMO and its progress made in various IMO technical meetings on the development of IBS which is perceived as an effective aid to proper bridge lookout and those standards adopted by classification societies on the composition of workstation at bridge in order to identify the international trend on regulating required equipment function of workstation of IBS the regulatory review process and technical recommendations related thereto.

• Nutrition Research and Practice
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• 제17권6호
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• pp.1201-1210
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• 2023

BACKGROUND/OBJECTIVES: The dietary intake of foods with fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) is known to adversely affect patients with irritable bowel syndrome (IBS). However, the effects of FODMAP have been studied predominantly among Western populations. This study aimed to identify foods high in FODMAP content which form a part of the Korean adult diet and obtain basic data for the preparation of IBS guidelines. SUBJECTS/METHODS: An online survey of 1,000 adults from the general population in the age group of 20 to 40 years was performed. Data from 787 participants (men, 386; women, 401) were analyzed. The general characteristics of the participants, health status, IBS diagnosis using the Rome III diagnostic criteria, semi-quantitative food frequency questionnaire findings, and food items causing symptoms were analyzed. RESULTS: Overall, 169 participants (21.5%) had IBS. The contribution of the FODMAP nutrients in both IBS and healthy groups was as follows: fructan > lactose > excess fructose > sorbitol > mannitol > galacto-oligosaccharides (GOS). The fructan intake was 4.6 ± 2.2 g/day and 4.3 ± 2.5 g/day in the IBS and healthy groups (P = 0.014), respectively. In the IBS group, the ratio of the intake of fructan to the total FODMAP intake was 39.5%, 29.8%, and 5.8% through onions, garlic, and bananas, respectively. CONCLUSIONS: Fructan was the FODMAP nutrient most consumed by Korean adults. Therefore, given the difference in the dietary habits of each country's population, the dietary guidelines for IBS should be country specific.

• Journal of Korean Biological Nursing Science
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• 제22권2호
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• pp.148-156
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• 2020

Purpose: The purpose of this study was to develop a motivation-enhanced self-management (MESM) intervention for irritable bowel syndrome (IBS) and to evaluate its effects on female college students with IBS. Methods: The program was constructed to reflect the conceptual framework of the self-determination theory including autonomous motivation enhancement strategy through the satisfaction of psychological needs. The experimental group (n= 24) participated in the all eight weekly MESM sessions, and the control group (n= 25) received one hour education of IBS. Primary outcome measures were the IBS symptom severity scale (IBS-SSS) and the IBS specific quality of life (IBS-QOL), and assessed at the baseline and at eight and 16 weeks after the allocation. Others were autonomous motivation, self-determined behavior, and psychological distress assessed at the baseline and at eight weeks. Results: The experimental group showed improvement in the IBS-SSS (p< .001) at 16 weeks compared to the control group. They showed markedly more improvement in the IBS QOL (p= .008), but the magnitude of this difference decreased at 16 weeks. The experimental group showed improvements in autonomous motivation (p= .035), self-determined behavior (p= .023), and psychological distress (p= .044) compared to the control group. Conclusion: Study results suggest that the MESM intervention for female college students may effectively improve the IBS-SSS and the QOL.

• Journal of Neurogastroenterology and Motility
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• 제24권4호
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• pp.628-642
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• 2018

Background/Aims A Subset of patients with irritable bowel syndrome (IBS) may have mild inflammation due to immune activation. Toll-like receptors (TLRs) and cytokines may cause intestinal inflammation. We studied their expression in relation to gut microbiota. Methods Expression of TLRs and cytokines was assessed in 47 IBS patients (Rome III) and 25 controls using quantitative real-time polymerase chain reaction. Immunohistochemistry was further performed to confirm the expression of TLR-4 and TLR-5. Results Of 47 patients with IBS, 20 had constipation (IBS-C), 20 diarrhea (IBS-D), and 7 unclassified (IBS-U). The mRNA levels of TLR-4 and TLR-5 were up-regulated in IBS patients than controls (P = 0.013 and P < 0.001, respectively). Expression of TLR-4 and TLR-5 at protein level was 4.2-folds and 6.6-folds higher in IBS-D than controls. The mRNA levels of IL-6 (P = 0.003), C-X-C motif chemokine ligand 11 (CXCL-11) (P < 0.001) and C-X-C motif chemokine receptor 3 (CXCR-3) (P < 0.001) were higher among IBS patients than controls. Expression of IL-6 (P = 0.002), CXCL-11 (P < 0.001), and CXCR-3 (P < 0.001) were up-regulated and IL-10 (P = 0.012) was down-regulated in IBS-D patients than controls. Positive correlation was seen between TLR-4 and IL-6 (P = 0.043), CXCR-3, and CXCL-11 (P = 0.047), and IL-6 and CXCR-3 (P = 0.003). Stool frequency per week showed positive correlation with mRNA levels of TLR-4 (P = 0.016) and CXCR-3 (P = 0.005), but inversely correlated with IL-10 (P = 0.002). Copy number of Lactobacillus (P = 0.045) and Bifidobacterium (P = 0.011) showed correlation with IL-10 in IBS-C, while Gram-positive (P = 0.031) and Gram-negative bacteria (P = 0.010) showed correlation with CXCL-11 in IBS-D patients. Conclusions Altered immune activation in response to dysbiotic microbiota may promote intestinal inflammation in a subset of patients with IBS.

• 디지털융복합연구
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• 제16권11호
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• pp.501-509
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• 2018

수용­전념 치료(ACT)가 과민성 대장 증후군이 있는 사람들의 과민성 대장 증후군(IBS) 증상 심도, 지각된 스트레스, 과민성 대장 증후군 특이적 삶의 질 및 수용 행동에 미치는 효과를 알아보았다. 성인 156명에게 과민성 대장 증후군 진단척도를 실시한 뒤 14명을 참가자로 선정하였고, IBS 증상 심도, 지각된 스트레스, 삶의 질 및 수용 행동에 관한 사전 검사를 실시하여 치료 집단에 7명, 통제 집단에 7명을 할당하였다. 프로그램은 주 2회씩 총 10회기가 진행 되었고, 사후 검사 및 4주 후 추적 검사가 실시되었다. 최종 참여자는 치료 집단에 6명, 통제 집단에 6명이다. 연구 결과, 수용 전념 치료 프로그램에 따른 IBS 증상 심도의 변화는 유의하지 않았지만, 지각된 스트레스와 삶의 질 및 수용 행동 상의 변화는 유의하였다. 적은 수의 참가자로 치료 프로그램이 진행되어 참여 인원이 증가된 후속 연구의 필요성은 있겠으나, 과민성 대장 증후군이 있는 사람들의 스트레스 수준을 낮추고 삶의 질과 수용 행동을 높이는데 수용전념치료가 효과적임을 입증하는 경험적인 증거를 제공한다.

• 성인간호학회지
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• 제17권5호
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• pp.802-812
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• 2005

Purpose: to determine the effects of hand acupuncture on IBS-affected college women's bowel symptoms and psychologic health by applying the therapy to them. Method: The researcher sampled the nursing student attending a college of nursing science in Seoul and checked if they were affected by IBS in reference to the Rome II Criteria. Students were classified into a experimental group(21 subjects) and a control group(19 subjects). Hand acupuncture was applied to the experimental group 8 rounds for 4 weeks; each round lasted 30 minutes. Data were collected for 8 weeks from October 11 to December 1, 2004. The collected data were analyzed using the SPSS 12.0 program. Result: After the therapy, frequency(p=.005), distress(p=.001) and disability (p=.000) associated IBS bowel symptom and anxiety were significantly lowered in the experimental group(p=.026). Conclusions: It was confirmed through this study that the hand acupuncture would be effective in relieving IBS bowel symptoms and anxiety.

• Journal of Korean Biological Nursing Science
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• 제13권1호
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• pp.61-71
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• 2011

Purpose: The purpose of the present study was to investigate the prevalence, subtypes and risk factors of irritable bowel syndrome by ROME-III among Korean university students. Methods: This study was descriptive survey research. The sampls were 796 and variables were measured by structured questionaire. Rome-III criteria was used for diagnosis of IBS. The gathered data were analyzed with %, $x^2$-test, t-test, logistic regression by SPSS win 17.0. Results: The students with IBS were 61 (7.7%) and the most of the subtype was IBS-M (42.6%). Meal (times/day), breakfast, stress, quality of sleep, neuroticism, bodily pain, general health, social function, role emotional restriction, mental health, somatization, obcessive-compulsive state, depression, anxiety, hostility, global severity index, positive symptom distress index, positive symptom were significantly different between IBS group and non-IBS group. The prevalence of IBS was low in the higher score of role emotional in general health state. There were more 2 times students who had score of the obsessive-compulsive in psychological health over the 50 than below the 50 in IBS group. Conclusion: 7.7% of students were diagnosed by Rome-III criteria and the most of the sybtype was IBS-M. The risk factors of IBS were role emotional restriction, obsessive-compulsive state.