• 한국보건간호학회지
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• 제33권2호
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• pp.228-241
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• 2019

Purpose: The purpose of this study was to evaluate the prevalence, awareness, treatment and control of hypertension, diabetes, and dyslipidemia among women with rheumatoid arthritis. Methods: This cross-sectional study of 288 women with rheumatoid arthritis was conducted in a university-affiliated hospital. Data were collected by reviewing the women's medical charts and self-report questionnaires. Results: The prevalence of hypertension, diabetes and dyslipidemia was 27.8%, 5.9% and 48.3%, respectively. Despite the high prevalence of dyslipidemia, the subjects'awareness of it and its treatment rates were the lowest, which resulted in a low control rate. Of the 288 subjects, 158 (55%) had at least one of the three conditions. The prevalence of the combination of cardiovascular risk factors increased with age, and 32.7% of those aged 60 or older had two or three of the cardiovascular risk factors. Combinations of cardiovascular risk factors were significantly related with severe pain and fatigue. Conclusion: Cardiovascular risk factors were highly prevalent among the women with rheumatoid arthritis, but the rates of awareness, treatment, and control were suboptimal. There is a pressing need to facilitate the prevention, early detection and appropriate management of hypertension, diabetes and dyslipidemia among patients with rheumatoid arthritis in order to prevent cardiovascular disease.

• 보건교육건강증진학회지
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• 제21권2호
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• pp.215-231
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• 2004

The purpose of this study was to examine what factors affected patients who suffered from essential hypertension compliance with health behaviors, to help build a successful strategy to step up their compliance with health behaviors, and to seek effective ways to implement health education programs for patients with chronic disease. The subjects in this study were 60 people selected from among the patients who were diagnosed by physicians as having essential hypertension in S General Hospital in the city of P from April 10 through July 30, 2000, after health education was provided four times a month. The quasi- experimental design based on a control group pretest-posttest design was employed. The subjects were divided into three groups of 20 patients each： one was an experimental group to receive education in one-to-one interview, another was an experimental group to receive education as a group, and the third was a control group. The two experimental groups learned the same material through different methods, and the control group was given the same teaching materials and asked to comply with health behaviors on their own without instruction. After the three-week education was implemented in different ways, their compliance with health behaviors was measured. Collected data was analyzed by t-test, paired test, one-way analysis of variance, correlation analysis and regression analysis procedures. The findings of this study were as follows： 1. Concerning the effective type of health education, the group education produced the best results, followed by the one-to-one interviews and the sole use of print media. 2. Regarding the effect of compliance with health behaviors, the group- educated group got the highest score in compliance with health behaviors, but blood pressure lowered more significantly in the individual interview group. And the compliance with health behaviors had a significant negative correlational relationship with both systolic and diastolic blood pressure. 3. Parameter that had most significant correlational relationship with compliance with health behaviors was health locus of control, followed by self-efficacy and health perception. But there was no significant correlational relationship between compliance with health behaviors and knowledge of hypertension. 4. As a result of analyzing the impact of knowledge of hypertension, health locus of control, self-efficacy and health perception on compliance with health behaviors, self-efficacy was found to exercise most influence. Above-mentioned findings suggested that group education or one- to-one discussion would be more effective for health care for hypertension in koreans, as they could serve to have patients realize their own responsibility for health and to motivate their compliance with health behaviors, and there was a need to more positively utilize educational intervention for patients with chronic diseases, which could elevate not only compliance with health behaviors but self-efficacy.

• 한국임상수의학회지
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• 제37권6호
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• pp.311-316
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• 2020

Biomarkers used in dogs with heartworm disease include N-terminal pro B-type natriuretic peptide (NT-proBNP) and cardiac troponin I (cTnI), which are associated with damage to the myocardium. Pulmonary hypertension is one of the clinical signs of canine heartworm disease. The purpose of this study is to investigate the change in the concentration of each biomarker, severity of pulmonary hypertension and the correlation between biomarkers according to the severity of clinical signs. Five healthy dogs and 10 heartworm-infected dogs were recruited for the study. The heartworm-infected group was classified based on the history, clinical signs, and blood assay, thoracic radiography, and echocardiography after confirming the infection according to the results of the commercial ELISA kit (SNAP test, IDEXX Laboratories, Maine, USA). NT-proBNP was higher in the severely infected group than the control group (p < 0.05); cTnI was also higher in the severely infected group than the control group (p < 0.05). The pressure gradient of pulmonary hypertension was higher in the severe group than the mild group (p < 0.05). The severity of pulmonary hypertension was correlated with NT-proBNP (r = 0.818, p < 0.01), cTnI (r = 0.894, p < 0.01). When the correlation of the two serum values for each group was examined, a correlation was not found in the mild group (r = 0.707, p = 0.182), but a correlation was found in the severe group (r = 0.9, p < 0.05). NT-proBNP and cTnI were significantly increased and correlated with severe clinical signs. Pulmonary hypertension was significant higher in the severe group than in the mild group (p < 0.05). Evaluation of blood biomarker concentration and severity of pulmonary hypertension and referring to each correlation between these indicators may be helpful to assess the severity of the heartworm disease.

• 대한본초학회지
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• 제39권3호
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• pp.69-76
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• 2024

Objectives : Hypertension (high blood pressure), one of the world's major chronic diseases, has a high mortality rate due to its high prevalence and complications, but its control rate is low. The proper management and control through appropriate exercise, diet management, and optimal drug choice can reduce the risk of death from hypertension. Although various antihypertensive drugs are used to treat hypertension, they also have numerous adverse effects. Alongside increased interest in the use of Traditional Herbal Formulas (THF) for hypertension treatment, the purpose of this study was to examine the vasodilative effects of 10 THF in the rat thoracic artery pre-contracted by potassiumchloride (KCl). Methods : THF were extracted with distilled water for 2 hours. The rat thoracic artery was suspended and contracted by KCl in the organ bath which contained 10 ml Krebs Henseleit (KH) buffer. THF extracts were added in a dose-dependent increase (10-1,000 ㎍/mL) to examine vasodilative effects. The vasodilative effects produced by THF were expressed as the percentage in response to KCl-induced contraction. Results : Among the 10 THF, Banhasasim-tang, Buhnsimgieum, Sagunja-tang, and Samul-tang showed vasodilative effects. And, Sipjeondaebo-tang, Ssanghwa-tang, Ojeok-san, Onkyung-tang, Yongdamsagan-tang, and Hyangsayukgunja-tang showed no significant vasodilative effects. Also, in co-administration with amlodipine, Banhasasim-tang showed higher vasodilative effects than amlodipine alone, and Buhnsimgieum showed greater vasodilative effects at low concentrations, but inhibited amlodipine's vasodilative effects at high concentrations. Conclusion : As a result of these studies, they will be expected to provide useful data to establish guidelines of combined administration of THF and western antihypertensive drugs for the treatment of hypertension.

• 농촌의학ㆍ지역보건
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• 제33권1호
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• pp.37-45
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• 2008

본 연구는 시설 신축 여부에 따른 환경요인이 고혈압 조절에 미치는 영향을 미치는 지 여부를 파악하기 위해 1994년부터 약 10여년 동안 시행되어 온 농촌의료서비스 개선사업에 의한 보건기관 신축 여부와 인구학적 개인 요인, 전문의 여부 등 의사 요인의 영향을 함께 고려하여 분석한 연구이다. 고혈압 조절에 영향을 미치는 요인에 관한 연구천성아, 나백주, 김철웅, 이무식 7는 주로 개인 특성에 대한 연구가 이미 수행되었지만 의사의 특성 요인 및 의료 조직 및 시설의 위치 등 환경 요인에 대한 분석은 미흡하였다.조사는 충청도 일부 지역 6개 시,군으로 농어촌의료서비스 개선사업 대상지역이다. 해당 지역의 6개 보건소 및 산하 59개 보건지소에 2005년 7월 1일부터 2006년 6월 30일까지 한번이라도 고혈압 진료를 위해 환자가 내원하거나 보건소 직원이 직접 방문하여 투약 혹은 상담을 한 내용이 기록된 자료 가운데 분석에 적합한 약 2만5천건의 고혈압 환자 진료 자료를 분석하였다.연구결과 전체적인 보건기관에 혈압수치 조절율은 53.9%이었으며 여성이 남성보다 혈압이 잘 조절되었으면 60대와 70대의 혈압 조절율이 유의하게 높았다(p<0.01). 또한 개선지역이 미개선 지역에 비해 혈압조절율이 유의하게 높았다(p<0.01). 전문의 기준으로 일반의에서 혈압조절율이 다변량 분석에서 유의하게 낮았다(p<0.01). 이 연구는 진료에 적합한 시설이 환자진료 과정에서 의료진의 만족도와 환자의 안정감을 향상시키고 이는 결국 환자관리의 순응도 등을 높이는데 기여하여 진료결과의 질적 향상에도 영향을 미칠 수 있음을 실증적으로 확인하였다. 이는 향후 농어촌의료서비스개선사업이 지역사회 건강결과 향상에 미치는 효과를 계량화 하는 기초 자료가 될 수 있을 것으로 판단한다.연구 기금본 연구는 한국개발연구원이 발주하고 한국보건사회연구원이 수행한 “농어촌의료서비스개선사업의 심층평가” 연구의 지원으로 수행하였습니다.감사의 말씀본 연구에 적극 협조해 주신 프로그램 개발업체 GST 이재익 사장과 민상익 연구원에게 깊은 감사를 드립니다.

• 한국산업보건학회지
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• 제24권4호
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• pp.556-565
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• 2014

Objectives: This study is aimed at inquiring into the grasp of real condition of working environment and improvements by calculating the hypertension distribution consequent on job stress risk and exposure level of alleviating factors. In addition, this study is intending to estimate the hypertension distribution through socio-demographic factors and level of stressors occurring at working environment, such as high workload, low control, low support, job insecurity, long working hours, low income. Methods: This study estimated the hypertension distribution using the tertiary Korean Working Conditions Survey data, and conducted comparative analysis according to the category of individual questionnaire items using odds ratio. Result: As a result of study, it was found that in the event that working environment satisfaction is low and business & an immediate superior's attitudes are negative, the hypertension distribution was high. Particularly, it was found that physical risk factor musculoskeletal risk factor, and mental risk factor in a workplace were all increasing the hypertension distribution. Conclusions: With the aged workers' labor market participation ratio increasing, hypertension could be a major issue in the field of Occupational Safety and Health. Thus, it's necessary that the relevant employer should lower the hypertension distribution through creation of pleasant working environment and inducement of workers to improve in the relations with their superiors. As for the uppermost limit of this study, there is a limit to clarifying the mechanism of hypertension through multivariate statistics analysis because it's difficult to establish causal relationship by individual questionnaire item as the working conditions survey is made by cross-sectional study. In the follow-up research, this study is going to do research on the mechanism of hypertension through questionnaire supplementation and in-depth analysis.

• Journal of Yeungnam Medical Science
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• 제11권1호
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• pp.109-114
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• 1994

이차성 고혈압은 일차성 고혈압에 비해 빈도가 매우 적지만 그 원인 인자를 교정했을때 정상 혈압으로 완치가 되거나 증상의 완화를 보일 수 있기 때문에 이차성 고혈압을 시사하는 소견들이 있을 때에는 원인을 조사하여 그에 맞는 적절한 치료를 하는 것이 매우 중요하다.

• 한국환경성돌연변이발암원학회지
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• 제22권3호
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• pp.157-163
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• 2002

The role of the kidney in initiating hypertension has been much debated. The SA gene is expressed in the kidney and is association with hypertension in man and in experimental animal models. Also, increased plasma concentrations of homocysteine have been found in patients with coronary artery disease (CAD) and hypertension. The genetic variation of methlene tetrahydrofolate reductase (MTHFR) gene is related to its enzyme activity and to the plasma homocysteine concentration. In view of the effect of SA and MTHFR as risk factor for cardiovascular diseases, we investigated the Pst I RFLP of the SA gene and C667T mutation of the MTHFR gene in the Korean patients with hypertension. There were no significant differences in the allele and genotype frequencies of these polymorphisms between normotensive and hypertensive subjects. Therefore, our results do not support a possible role of these genes on hypertension in Korean population.

• 대한간호학회지
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• 제35권7호
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• pp.1258-1267
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• 2005

Purpose: This study was aimed to evaluate the effect of an internet community on knowledge, self-efficacy, and self-care behavior in workers with hypertension. Method: The research design used was a nonequivalent control group pre-test and post-test design. Sixty hypertensive workers participated in this study(Exp.=29, Cont.=31). The data was collected from the 3rd of November 2003 to the 27th of February 2004 using an interview with questionnaires. Information related to hypertension was provided on the internet community weekly and an e-mail newsletter was sent in order to increase participation in the internet community. We used a tool developed by Park Young-Im(1994) that measured knowledge related to hypertension and self-efficacy. A tool developed by Jung Mi-Young(2001) was used for self-care behavior. The collected data was analyzed with an $x^2-test$ and t-test using the SPSS WIN 10.0 program. Result: The internet community helped workers with hypertension to increase their knowledge related to hypertension, as well as increasing their self-efficacy and self-care behavior. Conclusion: An internet community could be applied as hypertensive nursing intervention.

• 한방비만학회지
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• 제2권1호
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• pp.25-36
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• 2002

Objective: The purposes of this study are to know the relations of abdominal obesity and ischemic stroke and to know what index could represent the abdominal obesity appropriately. Methods. We have done case-control study and recruited 97 ischemic stroke patients and 117 controls. Case is matched by control by individual matching. All participants had questionnaire, interview and then were examined waist-hip ratio, waist circumference and body mass index. Results : WC, WHR and Hypertension history had differences in two groups, case and control groups. But BMI and other factors weren't significant. According to Quartile of Waist Circumference, the two groups had the differences in hypertension history, diabetes history, smoking status, WHR, BMI, and weight and in the Quartile of Waist-Hip Ratio Quartile, past history of hypertension and diabetes, WC, BMI and weight had the significances. Sex, Age Adjusted and Multivariate Odds Ratio (95% Confidence Interval) of WC Quartile are 2.083, 1.628, 4.491 and 4.418, 4.964, 12.306, and in WHR, the Ors are 2.252, 5.743, 15.776 and 2.632, 8.918, 23.596. Conclusions: We knew from these results that abdominal obesity is very important risk factor of ischemic stroke and WHR more than WC is a good indicator of abdominal obesity, so we should reduce the WHR to prevent of ischemic stroke.