• Natural Product Sciences
• /
• v.17 no.2
• /
• pp.85-89
• /
• 2011

Bioassay-guided fractionation of the $CHCl_3$-soluble fraction of a MeOH extract of the fruiting bodies of Hygrophorus russula led to the isolation of five ergosterol derivatives (1 - 5). The structures of these compounds were identified as ergosterol peroxide (1), ergosta-4,6,8(14),22-tetraen-3-one (2), ergosta-7,22-diene-3${\beta}$,5${\alpha}$,6${\alpha}$-triol (3), ergosta-7,22-diene-3${\beta}$,5${\alpha}$,6${\beta}$,9${\alpha}$-tetraol (4), and 5${\alpha}$,6${\alpha}$-epoxy-ergosta-8(14),22-diene-3${\beta}$,7${\alpha}$-diol (5) by comparing their physicochemical and spectral data with those in the literature. These compounds were evaluated for in vitro cytotoxicity against A549 and XF498 cancer cell lines. Most of the tested compounds, except for compound 3, exhibited moderate cytotoxicity against both A549 and XF498 cell lines with $IC_{50}$ values ranging from 10.2 to 18.3 ${\mu}g/ml$ and from 11.4 to 24.6 ${\mu}g/ml$, respectively.

• The Korean Journal of Mycology
• /
• v.16 no.4
• /
• pp.226-229
• /
• 1988

More than one-hundred-twenty specimens of Basidiomycetes, Ascomycetes and slime molds were collected in Seoul National Polytechnic University Campus during the priod from June 1984 to November 1987 and examined for identity. They were classified into 25 families, 53 genera and 81 species. Among them, one genus and 2 species were confirmed as unrecorded taxa in Korea. The unrecorded genus was genus Hapalopilus and was named 'Band Dal Busut' in vernacular. The unrecorded 2 species were Hapalopilus rutilans and Hygrophorus nitratus. They were named 'No Lan Ban Dal Busut' and 'Jil San Beot Geot Busut,' respectively and their characteristics were here reported.