• Title/Summary/Keyword: Hye-seok

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A Study on the Trend of Technology for the Treatment of Oil from Oilsands by Patent Analysis (오일샌드 오일 처리기술의 특허분석에 의한 기술동향 연구)

  • Park, Kun-Yik;Han, Sam-Duck;Han, Hye-Jung;Kang, Kyung-Seok;Bae, Wi-Sup;Rhee, Young-Woo
    • Clean Technology
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    • v.15 no.3
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    • pp.210-223
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    • 2009
  • As a kind of an energy source to replace petroleum, the importance of oilsands is being emphasized as time goes on. In this paper, the trend of technology for the treatment of oil from oilsands was scrutinized using the patent analysis. The patents analyzed here were limited to them issued from 1973 to 2009. The technology trend of oil treatment of oilsands was analyzed by classifying each patent based on the year of publication, the country, the type of technology, and the major applicant of the patent.

A Case Study of Simulation Game Development based on SNS Environment: Planet (SNS 기반 육성시뮬레이션 게임 개발 사례 : 행성)

  • Kim, JiHye;Park, HyeonChan;Mun, Seung-Gwan;Yun, Min-Seok;Kim, Yeong-Hwi;Kim, YeonSuk;Choi, YoungMee;Noh, WoongGi;Choo, MoonWon
    • Annual Conference of KIPS
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    • 2011.11a
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    • pp.1422-1425
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    • 2011
  • 본 논문에서 소개하는 '행성' 게임은 소셜 네트워크 접속자들이 주어진 공간과 자원으로 상품을 생산하거나 가공하고 교환함으로써 더 많은 상품을 생산해내는 물물교류 개념을 기본으로 한다. 새로운 행성에 정착한 인간들의 수렵과 채집, 육성, 가공, 건축을 위한 각자의 역할에 따른 생산과 소비, 그리고 상호간의 거래를 위한 의사소통 행위를 통하여 게임적인 재미와 동시에 경영과 유통과 관련된 경제활동의 기본적인 개념을 습득할 수 있게 하였다. 현재까지의 프로토타이핑 과정과 앞으로의 연구과제를 제시하고자 한다.

Human Pluripotent Stem Cell-Derived Alveolar Epithelial Cells as a Tool to Assess Cytotoxicity of Particulate Matter and Cigarette Smoke Extract

  • Jung-Hyun Kim;Minje Kang;Ji-Hye Jung;Seung-Joon Lee;Seok-Ho Hong
    • Development and Reproduction
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    • v.26 no.4
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    • pp.155-163
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    • 2022
  • Human pluripotent stem cells (hPSCs) can give rise to a vast array of differentiated derivatives, which have gained great attention in the field of in vitro toxicity evaluation. We have previously demonstrated that hPSC-derived alveolar epithelial cells (AECs) are phenotypically and functionally similar to primary AECs and could be more biologically relevant alternatives for assessing the potential toxic materials including in fine dust and cigarette smoking. Therefore, in this study, we employed hPSC-AECs to evaluate their responses to exposure of various concentrations of diesel particulate matter (dPM), cigarette smoke extract (CSE) and nicotine for 48 hrs in terms of cell death, inflammation, and oxidative stress. We found that all of these toxic materials significantly upregulated the transcription of pro-inflammatory cytokines such as IL-1α, IL-β, IL-6, and TNF-α. Furthermore, the exposure of dPM (100 ㎍/mL) strongly induced upregulation of genes related with cell death, inflammation, and oxidative stress compared with other concentrations of CSE and nicotine. These results suggest that hPSC-AECs could be a robust in vitro platform to evaluate pulmotoxicity of various air pollutants and harmful chemicals.

A New Record of Nematus tibialis Newman, 1837 (Hymenoptera: Tenthredinidae) from South Korea (한국의 미기록종 Nematus tibialis Newman, 1837 (벌목: 잎벌과)에 대한 보고)

  • Jae-Hyeon Lee;Hyojin Jeong;Hye-Rin Lee;Jin-Kyung Choi;Gwan-Seok Lee;Gi-Myeon Kwon;Deok-Seo Ku;Tae-Ho An;Wonhoon Lee
    • Korean journal of applied entomology
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    • v.62 no.1
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    • pp.21-27
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    • 2023
  • In this study, Nematus tibialis Newman, 1837 (Hymenoptera: Tenthredinidae), is firstly reported in South Korea. The manuscript provides diagnostic illustrations, diagnosis, color variations, development stages and distribution of N. tibialis.

A report of 12 unrecorded bacterial species isolated from Suncheon Bay in Korea

  • Seok Won Jang;Jung Hye Eom;Sanghwa Park
    • Korean Journal of Environmental Biology
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    • v.40 no.4
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    • pp.405-412
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    • 2022
  • Suncheon Bay Ecological Park, possessing abundant fisheries and biological diversity, was registered as a Ramsar wetland in Korea. Approximately 300 bacterial strains were isolated from the Suncheon Bay in a comprehensive study of indigenous prokaryotic species conducted during 2019-2020 in South Korea. A total of 12 bacterial strains were identified using 16S rRNA gene sequencing, demonstrating >98.7% sequence similarity with validly published species. These species were determined to be unrecorded bacterial species in Korea. A total of six strains were isolated from brackish water and Phragmites communis Trin (reed) species. These unrecorded species were phylogenetically diverse and belonged to three classes, six orders, and ten genera. Regarding the genus and class levels, the previously unrecorded species belonged to Jiella, Martelella, Rhizobium, Paracoccus, Rhodovulum, and Altererythrobacter of the class Alphaproteobacteria; Mycolicibacterium, Demequina, and Microbacterium of the class Actinobacteria; Confluentibacter of the class Flavobacteria. The twelve species were further characterized by gram staining, colony and cell morphology, biochemical properties, and phylogenetic position.

Changes in the Structure of Collaboration Network in Artificial Intelligence by National R&D Stage

  • Hyun, Mi Hwan;Lee, Hye Jin;Lim, Seok Jong;Lee, KangSan DaJeong
    • Journal of Information Science Theory and Practice
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    • v.10 no.spc
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    • pp.12-24
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    • 2022
  • This study attempted to investigate changes in collaboration structure for each stage of national Research and Development (R&D) in the artificial intelligence (AI) field through analysis of a co-author network for papers written under national R&D projects. For this, author information was extracted from national R&D outcomes in AI from 2014 to 2019. For such R&D outcomes, NTIS (National Science & Technology Information Service) information from the KISTI (Korea Institute of Science and Technology Information) was utilized. In research collaboration in AI, power function structure, in which research efforts are led by some influential researchers, is found. In other words, less than 30 percent is linked to the largest cluster, and a segmented network pattern in which small groups are primarily developed is observed. This means a large research group with high connectivity and a small group are connected with each other, and a sporadic link is found. However, the largest cluster grew larger and denser over time, which means that as research became more intensified, new researchers joined a mainstream network, expanding a scope of collaboration. Such research intensification has expanded the scale of a collaborative researcher group and increased the number of large studies. Instead of maintaining conventional collaborative relationships, in addition, the number of new researchers has risen, forming new relationships over time.

사학연금 사망률 전망 방법에 관한 연구

  • U, Hae-Bong;Baek, Hye-Yeon;Go, Gyeong-Pyo;An, Hyeong-Seok
    • Journal of Teachers' Pension
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    • v.2
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    • pp.181-206
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    • 2017
  • 출산율 하락과 기대여명 증가에 따라 인구구조의 고령화가 급격히 진행되고 있다. 이에 따라 소득보장이나 건강보장과 같은 사회보장제도의 장기 재정 불안정과 관련된 사회적 우려가 높다. 여러 세대를 거쳐 사회보장제도를 안정적으로 유지하기 위해서는 제도의 장기적 재정 상태에 대한 정확한 전망이 요청된다. 재정 상태에 대한 정확한 진단은 장기 재정 안정화를 위한 가장 기본적인 전제 조건이며, 정확한 재정 상태에 대한 평가 없이 재정 안정화를 위한 사회적 합의를 도출하는 것은 가능하지 않다. 본 연구는 사학연금의 장기 재정 전망에 필요한 사망률 전망 방법을 검토함으로써 사학연금 장기 재정 전망 작업의 정확성과 신뢰성을 높이고자 하는 목적을 가지고 있다. 보다 구체적으로, 본 연구는 연앙인구 및 사망 건수 자료가 제한적인 동시에 단기 시계열 자료만이 존재하는 사학연금 데이터베이스의 특성을 반영한 사망률 전망 모형을 구축하고 있다. 사학연금 남성 사망률 전망과 관련하여 본 연구에서 제안하는 모형은 목표 집단의 사망력 패턴과 밀접히 연관된 준거 집단을 통합적으로 모형화하는 정합적 사망률 모형(coherent mortality model)이다. 반면 관측된 사망 건수가 매우 제한적인 관계로 사학연금 데이터베이스에 기초하여 사망률을 전망하기 쉽지 않은 여성 사망률의 경우 통계청 장래인구추계에서 전망된 성별 사망확률 격차가 사학연금에도 적용될 수 있다는 가정하에 사학연금 여성 사망률을 전망하는 방법을 제안하고 있다.

Production of Casein Hydrolysates from Concentrated Skim Milk Using Ultrafiltration Techniques

  • Hee Song Kim;Dong Hun Yang;Seok Jun Park;Hye Jin Kim;Hyoung Su Park;Eui-Jong Lee;Mee-Ryung Lee
    • Journal of Dairy Science and Biotechnology
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    • v.41 no.3
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    • pp.149-156
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    • 2023
  • Milk protein is often fractionated/concentrated by using various techniques in dairy industries. Among these techniques, ultrafiltration (UF) is particularly efficient at concentrating the casein fraction of milk protein. The objectives of this study were to produce casein hydrolysates by concentrating the casein fraction in skim milk using the UF technique and to investigate the chemical composition of the casein hydrolysates. The skim milk was concentrated using a UF laboratory test unit equipped with 10 kDa and 30 kDa membranes. After UF, the protein content of the milk was concentrated up to ~7.2% and the Ca was concentrated up to ~196 mg/100 g of milk. Trypsin was then added to the concentrated skim milk to produce the casein hydrolysates. The results of sodium dodecyl sulphate-polyacrylamide gel electrophoresis showed that the casein fraction was not present after hydrolysis, indicating that casein in the milk had been hydrolyzed. The Ca content in the casein hydrolysates was much higher (p<0.05) compared to Ca content in commercial casein phosphopeptides (CPP) indicating that was acidified during the manufacture of commercial CPP. In conclusion, it seems that casein hydrolysates containing large concentrations of protein and Ca can also be made from concentrated UF milk without acidification or renneting.

Research on Development of Housing Welfare Program Satisfaction Evaluation Tool -Focusing on housing welfare programs for residents of long-term public rental housing in Seoul-

  • Yoon Hye JUNG;Jung Seok OH
    • The Journal of Economics, Marketing and Management
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    • v.12 no.1
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    • pp.53-64
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    • 2024
  • Purpose: The purpose of this study is to develop a satisfaction evaluation survey tool that reflects the characteristics of the program for housing welfare supported in long-term public rental housing in Seoul. Research design, data and methodology: The main research methods of the study were review of previous studies, literature review, and expert consultation. Results: First, the characteristics of each housing welfare program being promoted by Seoul City were summarized, and the characteristics were reflected in the evaluation survey tool. Second, the SERVOUAL model, a service quality model, was used to measure satisfaction with the housing welfare program and modified to suit the characteristics of the program. Third, an evaluation survey tool was constructed by dividing the evaluation tool into common questions and individual questions, and for the operation and sustainability of the housing welfare program, rather than just evaluating satisfaction, program loyalty was used as a survey item. Fourth, through expert advice, more than 10 evaluation questions for each housing welfare program were revised. Conclusions: The results of future research are expected to be used to prepare practical operation plans through annual monitoring of housing welfare programs and comparative analysis between programs.

Evaluation of the inhibitory effect of Gynostemma pentaphyllum extracts on CYP450 enzyme activities using LC-MS/MS

  • Jun Sang Yu;Young Seok Ji;So Young Jo;Xiang-Lan Piao;Hye Hyun Yoo
    • Mass Spectrometry Letters
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    • v.14 no.3
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    • pp.116-119
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    • 2023
  • Gynostemma pentaphyllum (Thunb.) Makino extract, a natural product with a history of traditional use, has gained attention for its potential health benefits. This study aimed to investigate its effects on key cytochrome P450 (CYP) enzymes using LC-MS/MS. Human liver microsomes and cDNA-expressed CYP2C8, CYP2C9, CYP2C19, and CYP3A4 supersomes were employed. Enzyme activity was assessed based on the formation of CYP-specific marker metabolites. The resulting data showed that the extract exhibited inhibitory effects on CYP2C8, CYP2C9, CYP2C19, and CYP3A4. Thus, G. pentaphyllum extract may influence the pharmacokinetics of drugs metabolized by CYP2C8, CYP2C9, CYP2C19, and CYP3A4. These findings emphasize the importance of considering potential herb-drug interactions when incorporating this extract into therapeutic regimens or dietary supplements.