• Biomolecules & Therapeutics
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• v.20 no.4
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• pp.399-405
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• 2012

Silver nanoparticles (AgNPs) are widely used nanoparticles and they are mainly used in antibacterial and personal care products. In this study, we evaluated the effect of AgNPs on cell death induction in the murine dendritic cell line DC2.4. DC2.4 cells exposed to AgNPs showed a marked decrease in cell viability and an induction of lactate dehydrogenase (LDH) leakage in a time- and dose-dependent manner. In addition, AgNPs promoted reactive oxygen species (ROS)-dependent apoptosis and AgNP-induced ROS triggered a decrease in mitochondrial membrane potential. The activation of the intracellular signal transduction pathway was also observed in cells cultured with AgNPs. Taken together, our data demonstrate that AgNPs are able to induce a cytotoxic effect in DCs through ROS generation. This study provides important information about the safety of AgNPs that may help in guiding the development of nanotechnology applications.

• Archives of Reconstructive Microsurgery
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• v.19 no.2
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• pp.88-92
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• 2010

The forefoot reconstruction is a challenging field for plastic surgeons. Weight bearing tolerability and stability are important factor of choosing reconstruction methods, but cosmetic aspect has to be considered. 51 year old man visited our clinic with extensive degloving injury on right forefoot by roller. The soft tissue defect started from metatarsal area to the toe tip including nails. We harvested the anterolateral thigh flap and transferred it to the forefoot defect area with nerve coaptation. The flap was successful without skin necrosis or other complications. Secondary flap debulking surgery was performed after ten months from initial operation. Patient was satisfied with functional and cosmetic outcomes. The patient was able to wear shoes and walk with adequate sensory recovery. As there is few report about reconstruction of forefoot soft tissue defects, we report a unique case of the anterolateral thigh innervated free flap reconstruction in degloving injury.

• Korean journal of food and cookery science
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• v.24 no.5
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• pp.722-728
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• 2008

This study was to investigate the quality characteristics of Seockryu-pyun by addition of different ratio of pomegranate juice and pomegranate concentrate (100%, 80%, 60%, 40%). Moisture and the pH increased as the content of pomegranate juice and pomegranate concentrate decreased respectivley. However, DPPH radical scavenging activity was decreased when adding pomegranate juice and pomegranate concentrate was decreased. With decreasing pomegranate juice addition, both the lightness(L) and yellowness(b) was significantly (p<0.05) higher, whereas, the redness(a) was significantly (p<0.05) lower. As addition of pomegranate concentrate was decreasing that lightness, a value and b value were higher. Texture profiles of hardness, adhesiveness, cohesiveness, gumminess, chewiness of Seockryu-pyun was not greatly showed significant difference among samples. Also, springiness was not significantly (p<0.05) different in any groups. For sensory evaluation, color and sourness were decreased as pomegranate juice and pomegranate concentrate was diluted. Seockryu-pyun, PJ3 made with addition of 60% pomegranate juice was the most preferred in overall acceptability. From the results, the most advisable mixture ratio of Seockryu-pyun was found as pomegranate juice 360 g (60%), water 240 g, mungbean starch 60 g and sugar 200 g.

• Food Science and Biotechnology
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• v.15 no.4
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• pp.529-533
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• 2006

To produce fresh-cut fruit products of high quality, the combined effects of postharvest calcium and heat treatment on Tsugaru apple were examined. Whole fruits were treated for 20 min at three different conditions: dipping in 3% $CaCl_2$ solution at $45^{\circ}C$ or ambient temperature, or in heated water at $45^{\circ}C$. The calcium content of the apples dipped in $CaCl_2$ solution at $45^{\circ}C$ was higher than that of the control and the non-heated calcium dipping. The fruits with calcium and heat treatment showed the same pattern of respiration rates as the control did during storage. The browning degree of the apple slices increased to approximately 3% after one-day storage, but no significant difference was observed between the treated and untreated apples. The fruits with $CaCl_2$ solution dipping at $45^{\circ}C$ had higher firmness than those with calcium dipping or heat treatment alone.

• Journal of KIISE:Information Networking
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• v.33 no.1
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• pp.1-8
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• 2006

Security protocols have usually been developed using informal design and verification techniques. However, many security protocols thought to be secure was found to be vulnerable later. Thus, the importance of formal specification and verification for analyzing the safely of protocols is increasing. With the rise of mobile communication networks, various mobile security protocols have been proposed. In this paper, we identify the security weakness of the ASK mobile Protocol using formal verification technique. In addition, we propose a new ASK protocol modifying its vulnerability and verify its robustness.

• Annual Conference of KIPS
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• 2019.10a
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• pp.262-264
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• 2019

최근 사물인터넷 분야에서 스마트 팩토리 부분은 많은 주목을 받고 있으며 관련된 연구도 많이 진행되고 있다. 기존의 스마트 팩토리 플랫폼은 제품 생산 효율성을 높여 비용을 줄이는 것을 목표로 센서로부터의 데이터 수집과 클라우드로의 전송, 대규모 데이터 분석을 통한 의사결정 등 자동화 부분에 집중되어 있다. 본 논문에서는 웹 GUI를 활용하여 응용 개발의 편의성을 높여 개발자가 아닌 공정관리자가 직접 공정을 제어할 수 있도록 했으며 유사 환경이 구축된 다른 공장에서 기존에 만들어진 공정 프로그램을 공유하고 재수정할 수 있는 시스템을 설계하였다. 또한, 프로토타입을 구현하여 제안된 웹 GUI기반 스마트 팩토리 공정 관리 및 공유 시스템의 운용 가능성을 검증하였다.

• Bulletin of the Korean Chemical Society
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• v.22 no.7
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• pp.685-688
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• 2001

A gas chromatography/mass spectrometric assay method has been developed for the simultaneous determination of benzidine (BZ), N-acetyl benzidine (ABZ) and N,N-diacetyl benzidine (DABZ) in rat urine. BZ, ABZ and DABZ were extracted from urine at pH 8 with ethyl ether. Conjugated urinary metabolites were extracted at pH 8 after hydrolysis with 1 M HCl for 30 min at 100 $^{\circ}C.$ The dried extract was dissolved in 100 ${\mu}{\ell}$ of ethylacetate and then injected in gas chromatography-mass spectrometric (GC-MS) system without further purification or modification. BZ, ABZ and DABZ have good chromatographic properties and offer very sensitive response for the EI-MS (SIM) without any derivatization. The recoveries for BZ, ABZ and DABZ were about 98.0, 81.8 and 71.4%, respectively, at pH 8.0 and the concentration of 5.0 ng/mL. The coefficients of variation of BZ and ABZ were less than 9.5% from 0.1 to 100 ng/mL and that of DABZ was less than 13% in the same concentration range. The detection limits of the assay were 0.01 ng/mL for both BZ and ABZ, and 0.05 ng/mL for DABZ in urine or plasma 1.0 mL.

• Journal of Acupuncture Research
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• v.36 no.4
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• pp.204-210
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• 2019

This study was performed to evaluate research studies utilizing ultrasound diagnostic units, the practitioners who performed the ultrasound assessments, and how they had been used primarily in tandem with the Korean Medicine Advanced Searching Integrated System. This study identified 46 studies following a literature search, and discovered that a Korean medicine doctor led the ultrasonography in 13 studies, a medical technician was responsible in 6 studies, a roentgenologist carried it out in 5, and 19 of the studies did not specify who had conducted it. Ultrasonography had been actively used in the course of the clinical practice of Korean medicine, and it may serve as a useful and reliable diagnostic tool for evaluating the effectiveness of Korean medicine. The results of this study will help to promote more ultrasound studies in the future.

• Proceedings of the Korea Water Resources Association Conference
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• 2019.05a
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• pp.320-320
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• 2019

유역의 수문 자료를 정확하게 분석하는 것은 수리 구조물을 효율적으로 운영하기 위한 중요한 요소이다. 인공신경망(Artificial Neural Networks, ANNs) 모형은 입 출력 자료의 비선형적인 관계를 해석할 수 있는 모형으로 강우-유출 해석 등 수문 분야에 다양하게 적용되어 왔다. 이후 기존의 인공신경망 모형을 연속적인(sequential) 자료의 분석에 더 적합하도록 개선한 회귀신경망(Recurrent Neural Networks, RNNs) 모형과 회귀신경망 모형의 '장기 의존성 문제'를 개선한 장단기메모리(Long Short-Term Memory Networks, 이하 LSTM)가 차례로 제안되었다. LSTM은 최근에 주목받는 딥 러닝(Deep learning) 기법의 하나로 수문 자료와 같은 시계열 자료의 분석에 뛰어난 성능을 보일 것으로 예상되며, 수문 분야에서 이에 대한 적용성 평가가 요구되고 있다. 본 연구에서는 인공신경망 모형과 LSTM 모형으로 유출량을 모의하여 두 모형의 성능을 비교하고 향후 LSTM 모형의 활용 가능성을 검토하고자 하였다. 나주 수위관측소의 수위 자료와 인접한 기상관측소의 강우량 자료로 모형의 입 출력 자료를 구성하여 강우 사상에 대한 시간별 유출량을 모의하였다. 연구 결과, 1시간 후의 유출량에 대해서는 두 모형 모두 뛰어난 모의 능력을 보였으나, 선행 시간이 길어질수록 LSTM의 정확성은 유지되는 반면 인공신경망 모형의 정확성은 점차 떨어지는 것으로 나타났다. 앞으로의 연구에서 유역 내 다양한 수리 구조물에 의한 유 출입량을 추가로 고려한다면 LSTM 모형의 활용성을 보다 더 확장할 수 있을 것이다.

• Journal of Korean Society for Quality Management
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• v.47 no.3
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• pp.553-569
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• 2019

Purpose: The purpose of this study is to identify the impact of conflicts and cooperation on project performance in the nuclear power plant construction project, thus contributing to the successful performance of project participants and the achievement of project objectives. Methods: This study used a method of conducting a survey of participants in the nuclear power plant construction project and verifying the hypothesis statistically. Results: The results of this study are as follows; First, role conflicts and relationship conflicts have negative effects on collaboration. Second, role conflicts have a negative effects on project performance, but conflict in relation has no significant effects on project performance. Third, collaboration has a positive effects on project performance. Finally, the communication quality in the relationship between conflict and collaboration has been shown to have a Moderated effect. Conclusion: In order to achieve the goal in the nuclear power plant construction project, the level of collaboration should be improved based on conflict management among project participants.