• Title/Summary/Keyword: Hye-seok

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Estimation of Attributable Burden due to Premature Death from Smoking in Korea (우리 나라 흡연으로 인한 조기사망의 질병부담)

  • Ha, Beom-Man;Kang, Jong-Won;Chang, Hye-Chung;Yoon, Seok-Jun
    • Journal of Preventive Medicine and Public Health
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    • v.34 no.3
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    • pp.191-199
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    • 2001
  • Objective : In this study, we focused on estimating the burden of premature death in Korea caused by smoking using the YLL(years of life lost due to premature death) measurement. Methods : First, we determined parameters: such as age-specific standard life expectancy, age on death, sex, and cause of death by analyzing the national death certificate data and life table collected during 1997. These were provided by the National Statistical Office. Secondly, we estimated the age group- specific years of life lost due to premature death by employing the standard expected years of life lost(SEYLL) measurement. Thirdly, the burden of premature death caused by smoking was estimated using the YLLs measurement which was developed by the global burden of disease study group. Fourthly, We calculated the risk related to smoking using the population attributable risk. Results : The following results were obtained in this study: 1) Premature death that is attributable to smoking in males could be prevented in 60.9%(513,582 person-year) by non-smoking. 2) The burden of premature death by smoking for female was prevented to 17.7%(513,582 person-year) by non-smoking. Conclusion : We found that the YLL method employed in this study was appropriate in quantifying the burden of premature death. This provides a rational basis for planning a national health policy regarding premature deaths caused by smoking and other related risk factors.

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E-cadherin and $\beta-catenin$ Expression and Mutation in Gastric Carcinomas (위암에서 E-cadherin과 $\beta-catenin$ 발현과 유전자 돌연변이에 관한 연구)

  • Kim Kwang Il;Park Sung-Hye;Han Sun-Ae;Chae Yang-Seok;Kim Insun
    • Journal of Gastric Cancer
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    • v.1 no.4
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    • pp.202-209
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    • 2001
  • Purpose: When cancer cels invade the stroma, they should be dissociated from the adjacent cells at first. E-cadherin and $\beta-catenin$ constitute an important protein complex associated with cellular adhesion, development, and differentiation, especially in epithelial cells. The role of E-cadherin and $\beta-catenin$ in gastric carcinogenesis were studied. Materials and Methods: The expression of E-cadherin and $\beta-catenin$ in gastric adenocarcinomas by using immunohistochemical staining and the mutation by using polymerase chain reaction- single stranded conformation polymorphism (PCR-SSCP) and sequencing were performed in 40 adenocarcinomas and 5 dysplasia of stomach. Thirteen cases, which had lymph node metastasis, were also included for immunohistochemical staining. Results: Inappropriate cytoplasmic and/or nuclear expression of a E-cadherin-$\beta-catenin$ complex was more frequent in poorly differentiated, diffuse type signet ring cell carcinomas than in well-differentiated, intestinal type adenocarcinomas (P<0.05). However, the expression was not related with clinical stage or lymph node metastasis. Mutation of E-cadherin was detected in 4 cases by using PCR-SSCP, whereas mutation of $\beta-catenin$ was detected in 2 cases. Conclusion: E-cadherin and $\beta-catenin$ seem to be important in gastric carcinogenesis, especially in poorly differentiated diffuse type.

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Evaluation of national health insurance coverage of periodontal scaling: A nationwide cohort study in Korea (국민건강보험공단 표본코호트 DB를 이용한 스케일링 보험급여화 전후 실태조사)

  • Kim, Young-Taek;Lee, Jae-Hong;Kweon, Helen Hye-In;Lee, Jung-Seok;Choi, Jung-Kyu;Kim, Dong-Wook;Choi, Seong-Ho
    • The Journal of the Korean dental association
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    • v.54 no.8
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    • pp.604-612
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    • 2016
  • The aim of this study was to evaluate the effect of national health insurance coverage of periodontal scaling using the National Health Insurance Service-National Sample Cohort for 2009-2013. After the enforcement of periodontal scaling covered by national health insurance, the number of patients diagnosed with periodontal disease and received treatment, has increased from 35,234 to 99,576 people in the last 4 years. Further, the number of patients who received the treatment of periodontal disease more than once, have also increased to around 69% in 2013 when compared to 2012. Moreover, the number of patients receiving periodontal scaling has been steadily increasing every year. Among the patients who visited hospital for periodontal disease, there has been an increase of 280%. As a result, continuous public relations and long-term research on the effect of periodontal scaling as a prophylactic treatment is necessary.

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A Study on the Fit Preference Tendency for Ready-to-wear by the Age and Obesity Level of Adult Women (성인 여성의 연령 비만도에 따른 기성복 맞음새 선호 경향 조사)

  • Seok, Hye-Jung;Kim, In-Suk
    • Journal of the Korean Home Economics Association
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    • v.41 no.9
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    • pp.17-29
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    • 2003
  • The objective of this study is to investigate the fit preference tendency for ready-to-wears(jackets, skirts, and slacks) of adult women and to find out the respective differences by the age range and the obesity level. The study method was the questionnaire survey with the subjects of 699 women of 20 up to 59 years of age. The questionnaire is composed of fit preference tendency, physical measurements, age, and occupation. For the data analysis, SPSS 90. program was used, and descriptive statistics, Crosstabs, ANOVA, Duncan's test, and t-test were conducted. The findings are as follows. 1. Regarding the fit preferred for each part of jackets, skirts, and slacks, among ready-to-wears, the 'thing with some extra width' in every part was most favored, followed by the 'thing fitting perfectly'. 2. The differences were found in the fit preference tendency by the age of adult women. The fit preference tendency was higher among those in their 20's than among those of the other age range, and those in their 30's and 40's preferred the clothes with less extra width in comparison with those in their 50's. 3. The differences were also found in the fit preference tendency by the obesity level of adult women. The fit preference tendency was high in the order of the emaciation, normalcy, and obesity types. 4. The fit preference tendency was found to be more affected by the obesity level than by the age. The fit preference tendency by the obesity level of each age range showed the differences in all of the age range. However, the normal type did not show the preference difference among the age ranges, in the fit preference tendency by the age range of each obesity level. Clothing manufacturing firms should understand the characteristics of consumers, such as their age, body type, extra width preferred, to provide the consumers of target market with suitable leeway, and they should design the clothing products which meet up these needs in style and silhouette.

Effect of Polyphenol Compound from Korean Pear(Pyrus pyrifolia Nakai) on Lipid Metabolism (한국산 배로부터 분리한 Polyphenol 분획물이 지질대사에 미치는 영향)

  • Choi, Hee-Jin;Park, Jung-Hye;Han, Ho-Seok;Son, Jun-Ho;Son, Kyu-Mok;Bae, Jong-Ho;Choi, Chung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.2
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    • pp.299-304
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    • 2004
  • This study was conducted to investigate the effects of the polyphenol fraction isolated from pear on the reduction of fat accumulation in rats fed on high fat diet for 5 weeks, which was examined by analyzing the lipid composition in serum, liver and feces biochemically. It was shown that the levels of total lipid and total cholesterol in serum were remarkably reduced in polyphenol fraction supplemented group as compared with the control group. The levels of total lipid and triglyceride were also significantly lower in polyphenol group than control group. The contents of total lipid, total cholesterol and triglyceride in feces were tended to be slightly increased in polyphenol group compared to control group. The total protein and albumin of polyphenol groups were lower compared to those of control group, which were not significant.

Effects of silanation time on shear bond strength between a gold alloy surface and metal bracket

  • Jung, Min-Ho;Shon, Won-Jun;Park, Young-Seok;Chung, Shin-Hye
    • The korean journal of orthodontics
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    • v.43 no.3
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    • pp.127-133
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    • 2013
  • Objective: We aimed to investigate the effects of silanation time on the shear bond strength (SBS) of metal brackets on gold alloy in a silicoating procedure and compare the SBS of metal brackets on gold alloy and enamel. Methods: Type III gold alloy plates were sandblasted with 30-${\mu}m$ silicon dioxide. Excess particles were removed with gentle air after silica coating, and silane was applied. Maxillary central-incisor metal brackets were bonded to each conditioned alloy surface with a light curing resin adhesive for 1 s, 30 s, 60 s, or 120 s after applying silane. The brackets were also bonded to 36 upper central incisors with the same adhesive. All samples were cured for 40 s with a light emitting diode curing light. The SBS was tested after 1 h and after 24 h. The adhesive remnant index (ARI) of the samples was also compared. Results: The 60-s and 120-s silanation time groups showed a higher SBS than the other groups (p < 0.05). Samples tested after 24 h showed a significantly higher SBS than did the samples tested after 1 h (p < 0.05). The 1-s group showed higher ARI scores. The one-way analysis of variance and Student-Newman-Keuls test showed that the SBS values of the 60-s and 120-s silanation time groups were not significantly different from the SBS values of enamel. Conclusions: Adequate silanation time is required to produce sufficient bond strength during silicoating.

A Study on the Preferable Learning Strategies in Science Learning of the Secondary School Students (과학 학습시 중 . 고등학생들이 선호하는 학습 전략에 관한 연구)

  • Kim, Jung-Seok;Kwon, Hye-Lyun;Chang, Nam-Kee
    • Journal of The Korean Association For Science Education
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    • v.17 no.1
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    • pp.103-113
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    • 1997
  • The purpose of this study was to identify the preferable learning strategies in science learning and to find out the relationship between these strategies and scientific achievement of students in the secondary school. The learning strategies were tested with two categories, self-focused and work-focused learning. The four types of learning strategies in science learning were analyzed, and they were named to organization, monitoring, elaboration and memorization strategies, which were defined by GSSS test. In the self-focused learning, the organization and monitoring strategies were preferred to the elaboration and memorization strategies. Middle school students had a preference for memorization strategy (p=0.000), whereas high school students had a preference for monitoring strategy (p=0.015). In the case of organization strategy, female groups were preferable to male groups (p=0.027). In the second form of learning types, work-focused learning, the memorization strategy was the same preference as organization and monitoring strategies in the secondary school students, especially the male groups of high school students. The preference of elaboration strategy was relative lower compared with that of self-focused learning type. Middle school students had a preference for monitoring strategy (p=0.001), whereas high school students had a preference for elaboration strategy (p=0.001). The difference of each preference between male and female groups was not shown. From the analysis of correlation between learning strategy and scientific achievement, it showed that the monitoring strategy was commonly correlated with scientific achievement. In the self-focused learning, elaboration and organization strategies were correlated with scientific achievement in high school students (p<0.05). In the work-focused learning, memorization strategy was correlated with scientific achievement in middle school students, especially in male groups (p<0.05).

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Determination of Atmospheric Perfluorocarbon Background Concentrations of fL/L Range at the Western Coastal Area of Korea

  • Kim, Hye-Kyeong;Yea, Sun-Kyung;Ro, Chul-Un;Lee, Chong-Bum;Jang, Meong-Do;Lee, Gang-Woong;Yoo, Eun-Jin;Han, Jin-Seok
    • Bulletin of the Korean Chemical Society
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    • v.23 no.2
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    • pp.301-308
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    • 2002
  • As part of perfluorocarbon (PFC) tracer release experiment conducted at the western coastal area of Korea in February 2001, the background concentration level of perfluorocarbons (PFCs) in the atmosphere was determined by gas chromatography with electron capture detector. Prior to the PFC tracer release experiment in the field, air samples were collected using active samplers and the background concentrations of PFCs were determined. The concentrations of perfluoromethylcyclohexane ($C_7F_{14}$, PMCH) in the western coastal area of Korea were in the range of 5.8-8.7 fL/L. The mean concentration of the PMCH in the region exhibited no significant spatial and temporal variations. This concentration level is somewhat higher and has larger standard deviation than those of studies previously conducted in USA and Europe on the background concentration levels of PFCs. Because the background concentration of PMCH in Korea is still very low and consistent temporally and spatially, the PMCH tracer can be used suitably for the studies of long-range atmospheric transport.

Validation and Factor Structure of Korean Version of the Beck Depression Inventory Second Edition (BDI-II) : In a University Student Sample (한국어판 벡 우울 설문지 2판의 신뢰도 및 요인분석 : 대학생을 대상으로)

  • Yu, Byeong-Kwan;Lee, Hye-Kyung;Lee, Koun-Seok
    • Korean Journal of Biological Psychiatry
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    • v.18 no.3
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    • pp.126-133
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    • 2011
  • Objectives The Beck Depression Inventory (BDI) is one of the most widely used self-report measures of depression in both research and clinical practice. The Beck Depression Inventory Second Edition (BDI-II) is the most recent version of the BDI. Validity of the BDI-II has been documented in other countries. This study examined the factor structure of the Korean version of BDI-II in a large sample of university students. Method Data were obtained from 2,529 students of Kongju National University. The factor structures of the Korean version of BDI-II were assessed using exploratory and confirmatory factor analysis. Results A high level of internal consistency and reliability (Cronbach's ${\alpha}$ = 0.91) and item homogeneity was confirmed. Exploratory factor analysis showed a two-factor structure (cognitive and somatic-affective), which was almost identical to the original model demonstrated by Beck et al. The following confirmatory factor analysis also supported the two-factor structure (cognitive and somatic-affective) is a better fit than the other two-factor structure (cognitive-affective and somatic). The higher mean score for women compared to men is consistent with the results of previous reports. Conclusion These data support the reliability and concurrent validity of the Korean version of BDI-II as a measure of depressive symptoms in nonclinical samples.

Carpal Tunnel Syndrome : Correlation between Magnetic Resonance Imaging and Nerve Conduction Study (수근관증후군 : 자기공명영상과신경전도검사의 상관 관계)

  • Park, Seong-Ho;Nam, Hyunwoo;Choi, Won-Joon;Yang, Hee Jin;Chung, Hye Won;Kim, Sam Soo;Lee, Sang Hyung;Lee, Yong-Seok;Song, Chi Sung;Chung, Young Seob;Lee, Kwang-Woo
    • Annals of Clinical Neurophysiology
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    • v.2 no.2
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    • pp.89-94
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    • 2000
  • Purpose : Carpal tunnel syndrome (CTS) is a disorder of median nerve at wrist. It is usually diagnosed through clinical manifestation and nerve conduction study (NCS). However, sometimes, NCS does not provide a reliable evidence to reach the diagnosis. Thus, authors performed this study to determine whether NCS was correlated with specific parameters measured on magnetic resonance imaging (MRI) which might become a potential complemental diagnostic tool. Methods : We performed MRI in 34 wrists of 18 patients with clinical manifestations of CTS and pathologic nerve conduction values and analyzed them at levels of the distal radioulnar joint, pisiform and hook of hamate, Results : Increase in the cross-sectional area of the median nerve at the pisiform level and flattening, increased signal intensity, and contrast enhancement of the median nerve at levels of the pisiform and hook of hamate were statistically significant. Change in cross sectional areas between the distal radioulnar joint and hamate and the signal intensities at levels of pisiform and hamate were well correlated with the median nerve conduction velocity. Conclusions : Characteristic MRI findings in CTS reported previously were well demonstrated and some of MRI parameters are well correlated with nerve conduction study. MRI, despite cost, may help in evaluating CTS.

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