• Environmental Analysis Health and Toxicology
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• v.13 no.3_4
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• pp.105-115
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• 1998

Reactive oxygen species (ROS) are highly reactive molecules due to their unpaired electron. They have been suspected as one of the major tissue damage inducers in biological metabolic systems. Antioxidant enzymes, such as catalase and superoxide dismutase, could not repair all the oxidative damages resulting from those excessive toxic ROS. It is, therefore, urgent to develop effective antioxidants to relieve from the oxidatire damages. In this study antioxidative effects were investigated by using two flavonoids such as quercetin and naringenin and a flavonoid-rich extract, Ginkgo biloba extract in combination with paraquat that is known as a strong generator of oxygen radicals. The results are summeringed as follows: 1. To assess radical scavenging ability reduction concentrations (IC$_{50}$) of 1,1-diphenyl-2-picrylhydrazine (DPPH) within 15 minutes were measured. The values of the IC$_{50}$ of quercetin and Ginkgo biloba extract were 15.4 $\mu$M and 13.2$\mu$g/ml, respectively. Their radical removing activities showed concentration-dependent manners. 2. In the hydrogen peroxide assay by using PMS-NADH system, quercetin, naringenin and Ginkgo biloba extract led to removing hydrogen peroxide in concentrationdependent manner whose removing abilities at 100$\mu$M or 100 $\mu$g/ml were 75.6, 25.8 and 26.0%, respectively. 3. In the hydrogen peroxide-induced rat blood hemolysis assay all three compounds led to similar effects whose hemolysis inhibition ratios at 100$\mu$M or 100$\mu$g/ml were 68.0, 5.14 and 55.8%, respectively. 4. In the xanthinee oxidase assay by measuring degree of NADH oxidation in the presence of hypoxanthine and xanthinee oxidase, both quercetin and Ginkgo biloba extract showed excellent activities showing 42.8 and 24.2% inhibiting xanthine oxidase activity at 100$\mu$M or 100$\mu$g/ml concentrations, respectively.

• Korean Journal of Pharmacognosy
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• v.44 no.3
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• pp.263-268
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• 2013

The protective role against oxidative stress under cellular system using C6 glioma cells was studied using the ethyl acetate (EtOAc) fraction, luteolin (1), and luteolin-7-glucoside (2) of Taraxacum coreanum. C6 glioma cells showed low cell viability and high generation of reactive oxygen species (ROS) by the treatment with generator of hydrogen peroxide ($H_2O_2$) and amyloid beta ($A{\beta}_{25-35}$). However, the treatment of the EtOAc fraction attenuated the cellular oxidative stress, resulting in significant elevation of cell viability. In addition, the production of ROS formation was also decreased by the treatment of the EtOAc fraction. Compounds 1 and 2 were isolated from the EtOAc fraction, and the protective effect was evaluated. Compounds 1 and 2 led to the increase of cell viability and decrease of production of ROS against oxidative stress by $H_2O_2$ and $A{\beta}_{25-35}$. The present study indicated that the EtOAc fraction, compounds 1 and 2 from T. coreanum demonstrated protective effects against oxidative stress, suggesting the preventive role against neurodegenerative diseases.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2009.05a
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• pp.181-184
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• 2009

In this study, flow visualization method to simulate internal flows of solid rocket motor in a water tunnel is introduced. The tunnel provides excellent visualization of vortex flows and has been used to propellant grain design of the solid rocket motor. A water tunnel is suggested for the research and the visualization test using dye, hydrogen bubble generator and PIV has been studied and discussed.

• Proceedings of the KIEE Conference
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• 2008.10c
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• pp.182-184
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• 2008

수소리니어 동력/발전시스템은 기존의 인프라를 이용한 개발이 가능한 이점과 고압축비, 초회박연소 실현에 의한 고효율, 저배기 달성이 가능한 장점을 가지고 있다. 또한 엔진 혹은 발전기의 구조변경 없이 다양한 연료를 사용이 가능하기 때문에 차세대 수소이용 기관으로 연구가 이루어지고 있다. 본 연구에서는 기존에 설계한 5kW급 리니어발전기의 성능향상을 위해 공극구조의 개선과 디텐트력 감소 설계를 했다. SPM 타입의 자석을 적용한 내충격 구조의 이동자 설계과 디텐트력 감소를 위한 치 형상설계가 이루어졌다.

• 전기의세계
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• v.21 no.4
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• pp.27-38
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• 1972

This paper discusses the characteristics about the ignition of D.C. main discharge is a plasma jet generator, manufactured for trial as non-transferred type, when the electrical energy appropriate to the ignition is supplied to the gap between the electrodes by using advance discharge of attenuating high frequency voltage generated by a high frequency oscillator with mercury spark gap. These characteristics are under the influences of (a) the length of mercury gap in high frequency oscillator and the quantity of hydrogen flow supplied to it, (b) the condenser capacity of the high frequency oscillator circuit, (c) the length of plasma jet torch in D.C. main discharge circuit and the quantity of argon flow supplied to it, (d) the circuit constants of D.C. main discharge circuit. The results for these characteristics, obtained by this research, are considered to be helpful to the designs for the ignition of a plasma jet as well as the welding arc stabilizer by high frequency discharge and the high frequency arc welder.

• Proceedings of the KIEE Conference
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• summer
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• pp.1242-1244
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• 2004

As rapid growth of energy demand in line with modem society's industrialization led to environmental pollution by fossil fuels, there are more and more interest and international research on energization of water, which is clean energy and comprising $70\%$ of earth. In offshore countries, the water is commercially used already and water has very attractive characteristics in terms of economy and efficiency compared to the existing gas welder. In this paper, the result from operating characteristic improvement of Gas Generator and Current-Controlled converter is to be considered into design in electrode, source and controller, standized into level of whole system design base.

• Proceedings of the KIPE Conference
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• 2008.10a
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• pp.184-186
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• 2008

리니어 발전기는 리니어 엔진의 시동에 필요한 연소조건을 만들기 위하여 전동기로 동작하다가 연소가 안정화되면 발전기로 동작을 하여 PCS(Power Conditioning System)를 통해서 전력을 계통으로 보내주게 된다. 리니어 엔진의 초기 시동을 하기 위하여 발전기는 운동주파수와 운동방향, 그리고 힘의 크기를 제어해야 하며, 발전 시에는 엔진의 동작에 맞도록 전력을 제어해야 한다. 이를 효율적으로 제어하기 위하여 MSC(Machine Side Converter)에서 상전류를 독립적으로 조절할 수 있는 H-bridge로 각 상을 구성하였다. LSI(Line Side Inverter)는 DC-Link 전압을 제어하여, MSC의 동력/발전 동작에 따라서 전력을 계통에서 받아오거나 전력을 계통으로 보내는 동작을 한다. 본 연구에서는 리니어 발전기 모델링를 통해서 PCS 제어 알고리즘을 확인하고 전체 시스템과 연동을 한 실제 운전특성에 대하여 살펴보았다.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.03a
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• pp.506-510
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• 2008

Ramjets are capable of much higher specific impulse than liquid rocket engines for high speed flight in the atmosphere. Ramjets, however, cannot generate thrust at low flight speed. Therefore, an additional propulsion device to accelerate the ramjet vehicle to a supersonic speed is required. In this study, we propose a novel ramjet propulsion system with a $H_2O_2$/Kerosene rocket as the accelerator for initial stage. In order to test the feasibility of this concept, consecutive reactors was built; one for the decomposition of $H_2O_2$ and the other for kerosene combustion. Decomposed $H_2O_2$ jet was injected to combustor through converging nozzle from gas generator and over this hot oxygen jet, kerosene was injected by spay injector. Through the various test cases, hypergolic ignition test was carried out and steady combustion was achieved.

• Proceedings of the Korean Vacuum Society Conference
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• 2011.02a
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• pp.421-422
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• 2011

The first part is about development of a liquid target for a neutron source, which is designed to overcome many of the limitations of traditional beam-target neutron generators by utilizing a liquid target neutron source. One of the most critical aspects of the beam-target neutron generator is the target integrity under the beam exposure. A liquid target can be a good solution to overcome damage to the target such as target erosion and depletion of hydrogen isotopes in the active layer, especially for the one operating at high neutron fluxes with no need for water cooling. There is no inherent target lifetime for the liquid target neutron generator when used with continuous refreshment of the target surface exposed to the energetic beam. In this work, liquid target containing hydrogen has been developed and tested in vacuum environment. Potentially, liquid targets could allow a point neutron source whose spatial extension is on the order of 1 to $10{\mu}m$. And the second is about the vacuum ultraviolet (VUV) spectrometer which is designed as a five-channel spectral system for ITER main plasma measurement. To develop and verify the design, a two-channel prototype system was fabricated with No. 3 (14.4 nm~31.8 nm) and No. 4 (29.0 nm~60.0 nm) among the five channels. For test of the prototype system, a hollow cathode lamp is used as a light source. The system is composed of a collimating mirror to collect the light from source to slit, and two holographic diffraction gratings with toroidal geometry to diffract and also to collimate the light from the common slit to detectors. The two gratings are positioned at different optical distances and heights as designed. To study the appropriate detector for ITER VUV system, two different electronic detectors of the back-illuminated charge coupled device and the micro-channel plate electron multiplier were installed and the performance has been investigated and compared in the same experimental conditions. The overall system performance was verified by measuring the spectrums.

• Journal of Food Hygiene and Safety
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• v.22 no.4
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• pp.235-242
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• 2007

This study was conducted to investigate the effect of aerosolized chemical sanitizers on inhibiting foodborne pathogens such as Escherichia coli O157:H7, Salmonella typhimurium, and Listeria monocytogenes. Five domestic commercial sanitizers subjected to five groups of sanitizer (chlorine-based, hydrogen peroxide-based, Iodophor-based, quaternary ammonium-based, and alcohol-based sanitizers) were aerosolized by an aerosol generator into a model cabinet and treated in laboratory media containing three pathogens for 1 h at room temperature. Aerosolized hydrogen peroxide-based and quaternary ammonium-based sanitizers were effective at inhibiting levels of E. coli O157:H7 (ca. 4-9 log reductions) whereas other aerosolized sanitizers such as chlorine-based, Iodophor-based, and alcohol-based sanitizers did not significantly reduced the levels of E. coli O157:H7. For S. typhimurium, the only aerosolized hydrogen peroxide-based sanitizer was effective and resulted in ca. 5-9 log reduction. Aerosolized hydrogen peroxide-based, Iodophor-based, and quaternary ammonium-based sanitizers significantly reduced levels of L. monocytogenes and especially, aerosolized quaternary ammonium-based sanitizer was strongly effective to kill L. monocytogenes, resulted in higher than 8.8 log reduction. And there was no special trend in inhibitory efficacy of sanitizers aerosolized by 1.6 or 2.4 MHz aerosol generators. From these results, aerosolization has great potential for use in commercial applications however it's efficacy could be very different depending on type of sanitizers.