• Investigative Magnetic Resonance Imaging
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• 제23권2호
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• pp.100-113
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• 2019

Sarcoidosis is a multisystem disease characterized by noncaseating granulomas. Cardiac involvement is known to have poor prognosis because it can manifest as a serious condition such as the conduction abnormality, heart failure, ventricular arrhythmia, or sudden cardiac death. Although early diagnosis and early treatment is critical to improve patient prognosis, the diagnosis of CS is challenging in most cases. Diagnosis usually relies on endomyocardial biopsy (EMB), but its diagnostic yield is low due to the incidence of patchy myocardial involvement. Guidelines for the diagnosis of CS recommend a combination of clinical, electrocardiographic, and imaging findings from various modalities, if EMB cannot confirm the diagnosis. Especially, the role of advanced imaging such as cardiac magnetic resonance (CMR) imaging and positron emission tomography (PET), has shown to be important not only for the diagnosis, but also for monitoring treatment response and prognostication. CMR can evaluate cardiac function and fibrotic scar with good specificity. Late gadolinium enhancement (LGE) in CMR shows a distinctive enhancement pattern for each disease, which may be useful for differential diagnosis of CS from other similar diseases. Effectively, T1 or T2 mapping techniques can be also used for early recognition of CS. In the meantime, PET can detect and quantify metabolic activity and can be used to monitor treatment response. Recently, the use of a hybrid CMR-PET has introduced to allow identify patients with active CS with excellent co-localization and better diagnostic accuracy than CMR or PET alone. However, CS may show various findings with a wide spectrum, therefore, radiologists should consider the possible differential diagnosis of CS including myocarditis, dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy, amyloidosis, and arrhythmogenic right ventricular cardiomyopathy. Radiologists should recognize the differences in various diseases that show the characteristics of mimicking CS, and try to get an accurate diagnosis of CS.

• Horticulture, Environment, and Biotechnology : HEB
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• 제59권6호
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• pp.805-813
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• 2018

Vanda is an aerial tropical orchid native to Thailand and nitrogen (N) fertilizer is mainly used to promote its growth and quality. However, little is known about the characteristics of N absorption and assimilation in Vanda. The objective of this study was to determine the appropriate source of N for Vanda cultivation. In this experiment, shoots and roots of Vanda 'Ratchaburi Fuchs-Katsura' were sprayed weekly with 100 ml of $^{15}N$ tracer solution (1) 10 mM of $^{15}NO_3{^-}$, (2) 5 mM of $^{15}NO_3{^-}$ plus 5 mM of $NH_4{^+}$, (3) 5 mM of $NO_3{^-}$ plus 5 mM of $^{15}NH_4{^+}$ and (4) 10 mM of $^{15}NH_4{^+}$. The results indicated that plants fed with a combined N fertilizer gave the highest of $^{15}N$ use efficiency ( $^{15}NUE$) of about 21.8%, 30 days after the first feeding (DAF), compared with those fed sole sources of $^{15}NO_3{^-}$ (21.0%) and $^{15}NH_4{^+}$ (16.6%). However, a sole nitrate fertilizer or combination fertilizer did not significantly affect the total N and labelled N content. Alanine was a major amino acid found in leaves and roots at 7 DAF, whereas glutamine was mainly found in stems. At 30 DAF, tyrosine and alanine became major components in the leaves, and glutamine decreased in stems when plants were fed with a single $^{15}NH_4{^+}$ source.

• Structural Engineering and Mechanics
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• 제78권5호
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• pp.599-610
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• 2021

Early detection of small concrete crack or reinforcement corrosion is necessary for Structural Health Monitoring (SHM). Global vibration based methods are advantageous over local methods because of simple equipment installation and cost efficiency. Among vibration based techniques, FRF based methods are preferred over modal based methods. In this study, a new coupled method using frequency response function (FRF) and proper orthogonal modes (POM) is proposed by using the dynamic characteristic of a damaged beam. For the numerical simulation, wave finite element (WFE), coupled with traditional finite element (FE) method is used for effectively incorporating the damage related information and faster computation. As reported in literature, hybrid combination of wave function based wave finite element method and shape function based finite element method can addresses the mid frequency modelling difficulty as it utilises the advantages of both the methods. It also reduces the dynamic matrix dimension. The algorithms are implemented on a three-dimensional reinforced concrete beam. Damage is modelled and studied for two scenarios, i.e., crack in concrete and rebar corrosion. Single and multiple damage locations with different damage length are also considered. The proposed methodology is found to be very sensitive to both single- and multiple- damage while being computationally efficient at the same time. It is observed that the detection of damage due to corrosion is more challenging than that of concrete crack. The similarity index obtained from the damage parameters shows that it can be a very effective indicator for appropriately indicating initiation of damage in concrete structure in the form of spread corrosion or invisible crack.

• Journal of East Asia Management
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• 제4권1호
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• pp.53-77
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• 2023

Modern company faces an uncertain future and a competitive environment and are seeking new technologies and creative products to ensure the corporate growth and survival in the market through continuous innovation. "University Industry Cooperation(UIC)" is a point of contact for overcoming the crisis faced by companies and universities in this era and a cooperation platform for mutual prosperity. As a subsidiary of a university, "Technology Holding Company(THC)" is attracting attention as a new window for UIC in Korea. The role of THC is to establish and foster the business opportunities of their subsidiaries and to return investment profits to the university ecosystem again. But recently, the life cycle of technology is getting shorter, and the development cost is steadily increasing. In particular, with the increase of hybrid projects based on convergence and combination, the risk of conducting research(R&D) and new product development(NPD) projects is gradually increasing. A PMO refers to a project management organization that can contribute to improving the success rate of projects with increasing uncertainty by supporting project visibility and appropriate decision-making. The purpose of this study is to raise a research question on whether THC's corporate performance can be improved when "Project Management System(PMO Service)" is introduced into the subsidiary incubation system of THC. This study proposes several research methods to identify the relationship between the introduction of PMO and the corporate performance of THC.

• Journal of Plant Biotechnology
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• 제49권4호
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• pp.331-338
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• 2022

Sunflower (Helianthus annuus L.) protoplasts were isolated from seven-day-old etiolated hypocotyls of 10 A line and four-week-old fully expanded young leaves of PI 441983 line in vitro seedlings using an enzymatic method. Purified protoplasts were collected by filtration and floatation in sucrose solution. Semi-solid protoplast culture was performed using the L4 regeneration protocol with various culture media and plating densities to achieve the highest efficiencies for protoplast culture of hypocotyl and mesophyll protoplasts of 10 A and PI 441983 lines, respectively. The concentrations in liquid L'4M medium and different plating densities were evaluated in two types of cytokinins, the adenine-type 6-benzyladenine (BA) and the phenylurea-type thidiazuron (TDZ). The highest colony formation was achieved in both sunflower lines when 0.5 mgL^-1 BA and 0.5 mgL^-1 TDZ were applied with a high plating density (3 × 10⁵ protoplasts mL^-1). These conditions led to 38.45% and 39.40% colony formation for hypocotyl protoplasts of the 10 A line and mesophyll protoplasts of the PI 441983 line, respectively. Moreover, many hypocotyl protoplast-derived colonies developed into micro-calli. In addition, superior development of both sunflower protoplasts was observed with all plating densities when BA was used in combination with TDZ. This finding will be applicable to future sunflower hybrid production via somatic hybridization.

• Structural Engineering and Mechanics
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• 제81권1호
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• pp.11-28
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• 2022

This paper considers the combination of cyclic and axial loads to investigate the hysteretic performance of H-section 6061-T6 aluminum alloy members. The hysteretic performance of aluminum alloy members is the basis for the seismic performance of aluminum alloy structures. Despite the prevalence of aluminum alloy reticulated shells structures worldwide, research into the seismic performance of aluminum alloy structures remains inadequate. To address this deficiency, we design and conduct cyclic axial load testing of three H-section members based on a reliable testing system. The influence of slenderness ratios and bending direction on the failure form, bearing capacity, and stiffness degradation of each member are analyzed. The experiment results show that overall buckling dominates the failure mechanism of all test members before local buckling occurs. As the load increases after overall buckling, the plasticity of the member develops, finally leading to local buckling and fracture failure. The results illustrate that the plasticity development of the local buckling position is the main reason for the stiffness degradation and failure of the member. Additionally, with the increase of the slenderness ratio, the energy-dissipation capacity and stiffness of the member decrease significantly. Simultaneously, a finite element model based on the Chaboche hybrid strengthening model is established according to the experiment, and the rationality of the constitutive model and validity of the finite element simulation method are verified. The parameter analysis of twenty-four members with different sections, slenderness ratios, bending directions, and boundary conditions are also carried out. Results show that the section size and boundary condition of the member have a significant influence on stiffness degradation and energy dissipation capacity. Based on the above, the appropriate material constitutive relationship and analysis method of H-section aluminum alloy members under cyclic loading are determined, providing a reference for the seismic design of aluminum alloy structures.

• Nuclear Engineering and Technology
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• 제27권4호
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• pp.571-581
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• 1995

원자력 발전소의 비상운전절차서는 작성단계부터 난점이 많이 있고, 작성된 절차서를 착인 및 검증하는 데에도 많은 어려움이 따른다 캐나다의 원자력 규제기관인 AECB에서도 원자력발전소의 운전 허가를 받는 데 있어 발전소 비상운전 절차서를 하나의 요구조건으로 삼고 있는데, 그 요구조건은 발전소 내외의 비상상황에 대처하기 위한 상세한 계획 및 절차를 개발하는 것이다. 본 보고서에서는 미국의 원자력 발전소 비상운전 계획을 참고하고 있는 캐나다 원자력 발전소용 비상운전절차 표준지침서를 검토하고, 캐나다 비상운전 절차서 들의 현재 경향을 알아보았으며, 캔두형 발전소들의 비상운전 절차를 사고의 범위(개별적인 사고의 종류 지정), 사고진단 방법(사건 대응적, 징후 대응적, 또는 이 두 가지 방법의흔합형), 절차서 형식 등을 중점으로 비교 검토하고, 각 절차서의 내용을 포괄적으로 종합하여 현재 건설중인 월성 원자력 발전소 2, 3, 4호기용 비상운전절차서의 기본방향을 징후 대응적절차서(사고진단이 안될 경우 사용)와 논리도표와 문장이 혼합된 형식의 사건파악적절차서로 이루어진 비상운전절차서로 제시하였다.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2023년도 봄 학술논문 발표대회
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• pp.87-88
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• 2023

In accordance with changes in the domestic construction environment, interest in off-site construction methods (factory-manufactured construction methods) including modular construction methods is rapidly increasing. Among various off-site (OSC) construction methods, the front runner is the steel-based box-type modular construction method. Compared to the existing wet construction method, the steel modular construction method is increasing in terms of securing economic feasibility by shortening the construction period and increasing the prefabrication rate. However, due to the recent rise in raw materials and a sharp rise in the exchange rate, the economic feasibility of the wet method is deteriorating compared to the wet method. Therefore, a hybrid between 9-Matrix-based OSC construction methods is considered as a solution, away from the steel-box type combination, and a comparative study of the construction process between each construction method is being conducted. It was analyzed that the PC modular construction method shortened the construction period by 9% compared to the existing steel modular construction method. On the other hand, when comparing the construction period of the Gayang-dong demonstration complex calculated assuming that all modules are applied, it is estimated that there will be a 12% reduction in construction period compared to the steel modular method and a whopping 43% compared to the RC method.

• 한국구조물진단유지관리공학회 논문집
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• 제13권5호통권57호
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• pp.109-120
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• 2009

본 논문은 외부 긴장된 긴장재의 손실 긴장력 추정에 대한 새로운 방법을 소개한다. 제안된 방법은 HGA과 FEM이 조합된 시스템 인식 기법으로 외부긴장된 긴장재의 손실된 긴장력이 추정된다. 제안된 기법의 인식변수로는 외부긴장 긴장재의 긴장력, 유효공칭직경, 단위길이당 질량과 레일리 감쇠 계수가 사용되었다. 첫째로 감쇠의 효과가 적용된 유한요소 모델 시스템을 모형화되고, 시스템 인식변수를 반복적으로 추정하는 역해석 기법을 이용하여 인식하게 된다. 마지막으로 3번의 수치실험을 통하여, 제안기법의 수치적 타당성 여부가 확인된다. 이때, 레일리 감쇠 계수를 제외한 인식변수들의 오차는 1%미만으로 인식된다.

• 한국잠사곤충학회지
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• 제36권1호
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• pp.8-25
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• 1994

본 시험은 누에 일대잡종육종에 있어 양질다사량 우량품종을 육성하기 위한 유전적 정보를 얻고자 수행되었다. 공급재료는 특성이 각각 다른 일, 중, 구 3개지역 6개 품종을 정역으로 이면교잡시켜 F1, F2 각각 30조합으로서 실용형질에 대한 육종가를 얻기 위해 교배조합별 잡종강세 및 조합능력의 검정한 결과는 다음과 같았다. 1. 형질들의 잡종강세는 사질형질인 견사량, 견사장에서 각각 24.51% 및 23.43%로 높았고, 견질형질인 전사종 및 사층중은 15.56%~15.71%, 17.14%~19.01%로서 유의한 강세를 보였으나 유충경과일수 등(5령 및 전령)에서는 부의 잡종강세를 나타내어 그 이용이 유의하였다. 2. 교배조합간의 잡종강세는 5령경과일수의 경우 C70 X Romogua, N9 X Romogua 조합이 높은 부의 강세현상을 보여 사육일수가 단축되는 방향으로, 전견중은 N9 X Romogua, N9 X Romogua 조합이 높은 강세현상을 보여 사육일수가 단축되는 방향으로, 전견중은 N9 X Sansurian의 암, Romogua X Sansurian의 수, 견층중은 암수에 관계없이, N9 X Sansurian의 견사장과 견사량에서는 Sansurian X Romogua의 정역간 교잡에서 각각 높았다. 3. 잡종강세의 모본효과는 N9 X C5, N63 X C70이 전견중과 견층중에서, 견사장에서는 Sansurian이 N63, C5 및 C70과 교잡될 때, 또한 견사량에서는 N9 X C70, N63 X C70이 각각 큰 경향이었다. 4. F1의 조합능력에서 분사량은 GCA, SCA 및 RCA의 전형질에서 유의하여 F1의 조합능력은 상가적 효과와 비상가적 효과가 함께 작용하였으나 형질에 따른 정역간 차이도 컸었다. 5. GCA의 효과는 경과일수에서는 Sansurian이 N9, C5가 견질형질(견장, 견폭, 전견중, 전층중 및 견층비율)과 사질형질(견사장, 견자량 및 생사량비율)에서 세대에 관계없이 높은 정의 효과를 나타내었다. 6. F1의 SCA효과에서 5령경과일수는 Sansurian X C70, romogua X C70, Sansurian X C5, Romogua X C5 등 구주종계와 중국종계간의 교잡에서 전견중과 견층중은 N9 X C5, C70 X Sansurian 이 암수에 관계없이, 또한 Rogmogua X Sansurian, N9 X C5가 F1, F2 간에, 견사량은 Romogua X N63 조합에서, 생사량비율은 Sansurian X Romogua 조합에서 각각 높게 평가되었다.