• Title/Summary/Keyword: Hybrid analysis

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Inflammatory Responses to Hydroxyapatite/Poly(lactic-co-glycolic acid) Scaffolds with Variation of Compositions (하이드록시아파타이트/락타이드 글리콜라이드 공중합체 지지체 조성에 따른 염증 완화 효과)

  • Jang, Ji Eun;Kim, Hye Min;Kim, Hyeongseok;Jeon, Dae Yeon;Park, Chan Hum;Kwon, Soon Yong;Chung, Jin Wha;Khang, Gilson
    • Polymer(Korea)
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    • v.38 no.2
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    • pp.156-163
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    • 2014
  • Hydroxyapatite has osteoconductivity, biocompatibility and noninflammatory, and it has been used clinically as artificial bone. In this study, we prepared hydroxyapatite/poly(lactic-co-glycolic acid) (PLGA) scaffolds using 0, 10, 20, 40 and 60 wt% of hydroxyapatite. We analyzed compressive strength, SEM analysis and FTIR for mechanical property of 3D hydroxyapatite/PLGA scaffolds. For biocompatibility tests, cell proliferation and viability were measured via MTT assay and SEM. We analyzed RT-PCR, FACS, histology (H&E, ED-1) for anti-inflammatory effect. This study showed that hydroxyapatite hybrid scaffolds have low inflammatory reaction compared with the PLGA. This result has a potential for the application of artificial bone graft material.

A Declaration of Love all the Same: Chicago and Modern Boy

  • Lee, Yujung
    • Cross-Cultural Studies
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    • v.20
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    • pp.241-274
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    • 2010
  • Due to the remarkable changes in the early twentieth century, the new invention and technology impacted peoples' everyday lives and people started to use the word, modern, to apply specifically to what pertained to present times and to designate a movement in what was new and not old-fashioned-a condition of newness. In the present day, however, the fantastic cultural changes of a century ago have now become commonplace, and what was once considered radically new is no longer a reason to marvel. This paper considers what it mean to be modern, once the new is no longer new. This question seems to remain as complicated and inappropriate to ponder because the consideration and impact of modernity cannot simply end with the end of an era. This paper investigates how the interconnected nature of popular culture provides apt illustrations to reveal the ambivalent nature of modernity and postmodernity. In doing so, first of all, this paper pays attentions to the notion of modernity and popular culture which emerged together in the early twentieth century when technology and mass consumer culture were promoted over the world. Also, it examines how popular culture represents a complex of mutually-interdependent perspectives and values that influence society and its institutions in various ways as the image of modernity continues to build in a postmodern era. That is, popular culture is identified as a large amount of intertextuality or collective experiences due to its intermingling of complementary distribution sources and techonology. Thus, this paper explores that popular culture devotes itself other images or narratives instead of referring to the real world and its output revisits the contemporary or past times in other places, being a means to produce and reproduce the accumulated images of the modern which shapes ceaseless simulacra of modernity over complexities of modernity. In order to find a critical juncture of the complex networks of modernity and popular culture, this paper considers two places, Chicago and Gyeongsung in the 1920s and 1930s in which the rapid modern experience took place and the modern movement forced the two societies to join the mass consumer culture whether willingly or not. Next, this paper considers two movies released in 2002 and 2008 that exemplify the complexities of modernity in Chicago and Gyeongung of the 1920s and 30s: Chicago and Modern Boy. Both films have common themes of the 1920s and 30s such as violence, adultery, femme fatal, and criminal themes with the forms of musical, dance, drama, and romance. Through the textual analysis of both Chicago and Modern Boy, two films are compared in observing the similar and different ways in which two films deal with the theme of modernity when they are represented from the contemporary perspectives. More specifically, this paper questions how modernity is present in contemporary cultural forms such as commercial and hybrid genre films; and how these movies create a new image of modern by embodying the double coding. Ultimately, this paper aims at realizing the paradox of double edged modernity and its ongoing discourse that controls people's consciousness through the medium of popular culture.

The Impact of the Korean Long-Term Care Insurance System on its Family Caregivers: Focusing on Family Caregiving Arrangement (노인장기요양보험제도에서 재가노인돌봄의 변화에 대한 연구)

  • Yang, Nanjoo;Choi, In-Hee
    • Korean Journal of Social Welfare Studies
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    • v.44 no.3
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    • pp.31-56
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    • 2013
  • The purpose of this study was to investigate the changes that family caregivers have experienced since using the Korean Long-Term Care Insurance(LTCI) system. In-depth interviews were conducted to determine how the services offered within the LTCI program had affected family caregiving and what changes they had incurred. Results from the qualitative content analysis show that the LTCI program significantly reduced the caregiving burden among family caregivers although burdens that family caregiver perceived varied greatly depending on the types of service that the family selected, and assigned family caregivers different identities and diverse roles(i.e., service user, family caregiver, certified care provider) depending on the service they use. The phenomenon of 'certified family care provider', which was not an intention of LTCI, demonstrates the practical need of elderly persons who require both care and the comfort of family and economic status of the family. Despite the positive impact of the LTCI policy on the family caregivers' burden and family relationship, the current LTCI system should be modified in order to better meet the needs of beneficiaries and their family caregivers.

Molecular phylogenetic relationships and speciation of Ranunculus cantoniensis (Ranunculaceae) (털개구리미나리(Ranunculus cantoniensis)의 분자계통학적 유연관계 및 종분화)

  • Lee, Chang Shook;Lee, Nam Sook;Yeau, Sung Hee
    • Korean Journal of Plant Taxonomy
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    • v.34 no.4
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    • pp.335-358
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    • 2004
  • To investigate molecular phylogenetic relationships and to test hypothesis of hybrid origin of Ranunculus cantoniensis (Ranunculaceae), the sequences of nrDNA and chloroplast DNA were analyzed for 8 taxa and 25 accessions including 5 accessions of outgroup. In the phylogenetic trees by analyses of maximum parsimony and maximum likelihood for ITS nrDNA sequences and combined data of psbA-trnH, rps16 and trnL sequences of cpDNA, R. cantoniensis was most closely related to R. chinensis, and then to R. taciroi and R. silerifolius. The molecular phylogenetic relationships were not congruent with the previous report that R. cantoniensis was most closely related to R. silerifolius. In the sequence analysis of ITS and psbA-trnH, rps16, trnL for R. cantoniensis and the related taxa, R. cantoniensis showed polymorphism. It supported that the polymorphism also was reported in chromosome number and karyotype of R. cantoniensis. Ranunculus cantoniensis shared the marker gene of R. chinensis and R. silerifolius in ITS, and one of R. silerifolius in cpDNA. These results supported the hypothesis that R. cantoniensis was caused by hybridization between R. chinensis and R. silerifolius based on chromosome number and karyotype, and also estimated that R. silerifolius might be of maternal origin and R. chinensis be paternal.

Correlation of Zoysia Grass (Zoysia. spp) Survival, Reproduction, and Floret Appearance Rates to Aid in Development of New Hybrid Zoysia Grass Cultivars (잔디 교잡 품종 개발을 위한 잔디 생존률, 재생산률 및 꽃대 출현률과의 상관관계)

  • Han, Gyung Deok;Jung, Ji Hyeon;Chung, Yong Suk
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.66 no.3
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    • pp.265-269
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    • 2021
  • This study was conducted to provide primary data through analysis of zoysia grass genetic resources to develop grass cultivars with beneficial novel properties. Zoysia grass (Zoysia. spp) is native to Korea, and is mainly propagated through stolons. However, since seed coat treatment technology was developed, the breeding of sexually reproductive grass variants has become possible, necessitating characterization of the floret appearance rate in the secured zoysia grass genetic resource before developing sexually reproductive cultivars. In this experiment, 549 grass lines were examined, revealing that florets appear in only 43 lines (7.81%). Survival rates after transplantation, and stolon generation rates displayed a significant positive correlation (Rho = 0.44). Survival rates after transfer, and rates of stolon production displayed very low correlations with floret appearance (Rho = -0.11 and Rho = -0.06). No significant results were obtained in 43 lines that displayed >20% floret appearance. To breed sexually reproductive grass variants, it is thus necessary to secure more genetic resources, considering the low rate of floret appearance. Finding traits that predict floret appearance at an early stage is also required.

Selection of Functional Lentinula edodes Strains with High Ergothioneine Content using Mono-mono Hybridization (단핵균주간 교잡에 의한 에르고티오네인 함량이 높은 기능성 표고 균주 선발)

  • Kim, Min-Jun;Jeong, Yeun Sug;Jang, Yeongseon;Ka, Kang-Hyeon
    • The Korean Journal of Mycology
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    • v.49 no.4
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    • pp.507-514
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    • 2021
  • Lentinula edodes have been cultivated extensively not only in South Korea but also in other Asian countries. In terms of taste and nutrition, it is a valuable mushroom that is comparable to other mushrooms. L. edodes contains various physiologically active compounds that promote human health. One compound, ergothioneine, exerts a powerful antioxidant function that inhibits cellular senescence. As it is not biosynthesized by plants or animals, L. edodes is very important for ergothioneine supply. The L. edodes cultivars Bambithyang (NIFoS 3404) and Sansanhyang (NIFoS 3420) of the National Institute of Forest Science (NIFoS) had higher ergothioneine content than the other cultivars, and 11 strains were obtained using mono-mono hybridization between them. The strains were inoculated into sawdust media to obtain fruiting bodies, and the ergothioneine content of each hybrid strain was confirmed using high-performance liquid chromatography (HPLC) analysis. Among the 11 strains, NIFoS 5108 had a higher ergothioneine content than the parental strains, Bambithyang (NIFoS 3404) and Sansanhyang (NIFoS 3420). This study revealed that it is possible to develop cultivars with improved specific functions using mono-mono hybridization.

Breeding of F1 Hybrid for Oriental Mustard(Brassica juncea L. Czern) Using the Cytoplasmic Male Sterile Line (웅성불임 인자를 이용한 갓(Brassica juncea L. Czern)의 F1 육종)

  • Park, Yong Ju;Min, Byung Whan
    • Journal of agriculture & life science
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    • v.52 no.6
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    • pp.27-36
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    • 2018
  • Recently, the demand for new cultivar of oriental mustard(Brassica juncea) is increased as the consumption of oriental mustard has increased dramatically in the market due to Kimchi is attracting the world's attention. However, absence of seed supply system can cause many problems including inbreeding depression due to self seed production, deterioration of the seed purity and heterogeneity of commercial seed. To establish the $F_1$ variety breeding system of oriental mustard, pure line and inbred lines were screened from inbreeding genetic resources. Male-sterile line was also selected from breeding combinations for the quality improvement of mustard. The combining ability from(Indojasai ${\times}$ Goheungdamyang) combinations and isolation line of(MS910 ${\times}$ Japan red mustard 8 ${\times}$ Ganghwa mustard 9) was highest, thus these lines were selected as parental lines. PCR(Polymerase Chain Reaction) and gene sequence analysis revealed that the genes related to CMS(orf263, orf220, and orf288) were distributed in mitochondria. The isolated lines from this study also showed good performance in yield test and farmhouse prove test.

Visual analysis of attention-based end-to-end speech recognition (어텐션 기반 엔드투엔드 음성인식 시각화 분석)

  • Lim, Seongmin;Goo, Jahyun;Kim, Hoirin
    • Phonetics and Speech Sciences
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    • v.11 no.1
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    • pp.41-49
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    • 2019
  • An end-to-end speech recognition model consisting of a single integrated neural network model was recently proposed. The end-to-end model does not need several training steps, and its structure is easy to understand. However, it is difficult to understand how the model recognizes speech internally. In this paper, we visualized and analyzed the attention-based end-to-end model to elucidate its internal mechanisms. We compared the acoustic model of the BLSTM-HMM hybrid model with the encoder of the end-to-end model, and visualized them using t-SNE to examine the difference between neural network layers. As a result, we were able to delineate the difference between the acoustic model and the end-to-end model encoder. Additionally, we analyzed the decoder of the end-to-end model from a language model perspective. Finally, we found that improving end-to-end model decoder is necessary to yield higher performance.

Case Study of Elementary School Classes based on Artificial Intelligence Education (인공지능 교육 기반 초등학교 수업 사례 분석)

  • Lee, Seungmin
    • Journal of The Korean Association of Information Education
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    • v.25 no.5
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    • pp.733-740
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    • 2021
  • The purpose of this study is to present the direction of elementary school AI education by analyzing cases of classes related to AI education in actual school settings. For this purpose, 19 classes were collected as elementary school class cases based on AI education. According to the result of analyzing the class case, it was confirmed that the class was designed in a hybrid aspect of learning content and method using AI. As a result of analyzing the achievement standards and learning goals, action verbs related to memory, understanding, and application were found in 8 classes using AI from a tool perspective. When class was divided into introduction, development, and rearrangement stages, the AI education element appeared the most in the development stage. On the other hand, when looking at the ratio of learning content and learning method of AI education elements in the development stage, the learning time for approaching AI education as a learning method was overwhelmingly high. Based on this, the following implications were derived. First, when designing the curriculum for schools and grades, it should be designed to comprehensively deal with AI as a learning content and method. Second, to supplement the understanding of AI, in the short term, it is necessary to secure the number of hours in practical subjects or creative experience activities, and in the long term, it is necessary to secure information subjects.

Is the Spinal Instability Neoplastic Score Accurate and Reliable in Predicting Vertebral Compression Fractures for Spinal Metastasis? A Systematic Review and Qualitative Analysis

  • Lee, Chang-Hyun;Hong, Jae Taek;Lee, Sun-Ho;Yi, Seong;Sohn, Moon-Jun;Kim, Sung Hwan;Chung, Chun Kee;Korean Spine Oncology Research Society
    • Journal of Korean Neurosurgical Society
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    • v.64 no.1
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    • pp.4-12
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    • 2021
  • Spinal metastases can present with varying degrees of mechanical instability. The Spinal Instability Neoplastic Score (SINS) was developed as a tool to assess spinal neoplastic-related instability while helping to guide referrals among oncology specialists. Some previous papers suggested that the SINS was accurate and reliable, while others disagreed with this opinion. We performed a systematic review regarding the SINS to evaluate its accuracy and precision in predicting vertebral compression fractures (VCFs). The 21 included studies investigated a total of 2118 patients. Thirteen studies dealt with the accuracy of SINS to predict post-radiotherapy VCFs, and eight dealt with the precision. Among 13 studies, 11 agreed that the SINS categories showed statistically significant accuracy in predicting VCF. Among eight studies, body collapse was effective for predicting VCFs in six studies, and alignment and bone lesion in two studies. Location has no statistical significance in predicting VCFs in any of the eight studies. The precision of SINS categories was substantial to excellent in six of eight studies. Among the six components of the SINS, the majority of the included studies reported that location showed near perfect agreement; body collapse, alignment, and posterolateral involvement showed moderate agreement; and bone lesion showed fair agreement. Bone lesion showed significant accuracy in predicting VCFs in half of eight studies, but displayed fair reliability in five of seven studies. Although location was indicated as having near perfect reliability, the component showed no accuracy for predicting VCFs in any of the studies and deleting or modifying the item needs to be considered. The SINS system may be accurate and reliable in predicting the occurrence of post-radiotherapy VCFs for spinal metastasis. Some components seem to be substantially weak and need to be revised.