• Title/Summary/Keyword: Hwang Yong-Ha

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Surgical Treatment of Esophageal Perforation (식도천공의 외과적 치료)

  • Park Jae Hong;Chei Chang Seck;Kim Dae Hwan;Hwang Sang Won;Yoo Byung Ha;Kim Han Yong
    • Journal of Chest Surgery
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    • v.39 no.3 s.260
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    • pp.214-219
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    • 2006
  • Background: Perforation of esophagus is relatively uncommon. but it is associated with high morbidity and mortality. Treatment and outcome are largely determined by the time of presentation. We performed a retrospective review of patients with esophageal perforation to assess the outcome of current management techniques. Material and Method: A retrospective chart review was performed on all patients treated for perforation of esophagus from March 1990 to March 2005. There were 28 patients (22 men and 6 women: mean age 51 years, range 17 to 82 years) The causes of the perforations were as follows: foreign body retention (9 patients), trauma (7 patients), spontaneous rupture (7 patients), and iatrogenic (5 pati-ients). 18 patients were presented within 24 hours and 10 patients were presented after 24 hours., Esophageal repair was performed in 21 ($75\%$) of them, 4 patients were treated with esophagectomy, 3 patients were treated with feeding gastrostomy and drainage. Result: Hospital mortality was $18\%$ and iatrogenic was increase the mortality rate (p < 0.05). Site of perforation, time from perforation, and treatment method had no influence on mortality. Postoprative leaks occurred in 4 patients after primary repair and were treated conservatively. Conclusion: Esophageal perforation remains a devastating event which is difficult to diagnose and manage. Primary repair can be performed in most patients with esophageal perforation regardless of time to presentation with a low mortality. Accurate diagnosis and early treatment are essential to the successful management of patients.

Complete Transsection of the Trachea by Blunt Trauma (둔상에 의한 기관 완전 절단 - 1예 보고 -)

  • Kim, Dae-Hwan;Yoo, Byung-Ha;Kim, Han-Yong;Hwang, Sang-Won
    • Journal of Chest Surgery
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    • v.40 no.1 s.270
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    • pp.79-82
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    • 2007
  • Tracheobronchial rupture due to blunt chest trauma is an uncommon injury although the incidence is increasing. Early diagnosis and primary repair of tracheobronchial rupture not only restore a normal lung function but also avoid the difficulties and complications associated with delayed diagnosis and repair We present one case of the tracheal transsection caused by traffic accident. Patient suffered from progressive dyspnea, subcutaneous emphysema on the neck and anterior chest wall and tension pneumothorax at both sides were noted. Although both closed thoracostomy were done, massive air leakage through the chest tube continued and subcutaneous emphysema spread to the anterior abdominal wall and scrotum and the degree of dyspnea aggravated. With the impression of tracheobronchial injury, we performed the emergency operation. Preoperative bronchoscopy at the operation room was proceeded, which revealed the trachea was near totally transsected in transverse direction. Operation was performed through collar incisiion on the anterior neck, and the trachea was anastomosed with 4-0 $Vicryl^{(R)}$ interruptedly. Postoperative course were uneventful and patient discharged without any complications.

Calibration and Validation of SWAT Model for Long Term Simulation of Runoff and Sediment Transport at the Nakdong River Basin (낙동강유역의 장기 유역 유출 및 유사 모의를 위한 SWAT 모형의 검보정)

  • Lee, Eun-Jung;Jang, Eun-Kyung;Kim, Tae-Keun;Hwang, Man-Ha;Kwon, Yong-Sung
    • Proceedings of the Korea Water Resources Association Conference
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    • 2012.05a
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    • pp.881-881
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    • 2012
  • 낙동강유역에는 4대강 사업으로 8개의 보가 낙동강 본류에 새롭게 설치되었으며, 따라서 상류로부터 유입되는 유사가 보상류에 퇴적되어 하천제방이나 하천구조물의 안전을 위협할 수 있다. 또한 홍수시에는 농경지의 매몰과 저수지의 퇴적현상이 발생하는 등 유역유사에 의한 다양한 문제가 발생할 수 있으며, 강우로부터 유출되는 유사는 강우사상에 따라 빠르게 변할 수 있으나 수체에 즉각적인 영향을 유발하지 않을 경우 만성적인 특성으로 인해 침전물을 계속 이동시키며 축적되는 문제가 발생한다. 따라서 이러한 문제를 사전에 예측하고 낙동강유역에 대한 유역유사관리 대책마련을 마련하기 위해 유역유출과 유사의 이송 및 퇴적양상을 분석하여 유역관리를 위한 자료를 구축할 필요가 있다. 이러한 기초자료 분석을 위해 활용되는 유역모형 중 SWAT(Soil and Water Assessment Tool) 모형은 장기간 유역 유출로 인한 유사 모의를 수행하는데 가장 많이 활용되는 모형이며, 미국 농무성 농업연구소(USDA Agricultural Research Service, ARS)의 Jeff Amold 등에 의해 개발된 모형이다. SWAT 모형은 장기유출 및 유사 발생에 대한 시 공간적 변화를 모의하는 모형으로 넓은 범위의 유역에 대해 일단위 모의 간격으로 최대 100년까지 모의가 가능한 장기유역 모의에 최적화된 모형이다. 본 논문에서는 SWAT 모형을 이용하여 낙동강유역의 장기 유역 유출 및 유사 모의를 수행하기위해 2004년에서 2009년까지의 유출량 자료와 유량-유사량관계곡선 등을 이용하여 본류 및 지류 유출구 주요지점에 대해 검보정을 수행하고자 한다. 모의의 정확도 향상을 위해 안동댐, 임하댐, 영천댐, 합천댐, 남강댐, 밀양댐 및 낙동강 본류 등 총 7개 유역으로 구분하여 SWAT 모형을 구축하였으며, 각 유역별로 유출량과 유사량에 대하여 각각 보정 및 검증을 수행하였다. 낙동강 본류유역 총 7개의 댐 방류량자료와 20개의 대형하수종말처리장 방류량자료를 이용한 낙동강유역의 유출량 보정 및 검증 결과, 모의치가 실측치를 잘 반영하고 있는 것으로 나타났다. 또한 총 11개 지점의 수위관측소에 대해 유사량 측정 성과를 이용한 유사량 보정 및 검증 결과, 강우시 유사량 모의값은 유출량-유사량관계곡선 식을 잘 반영하였으나, 비강우시에는 모의값이 관계곡선 식의 결과값보다 대체적으로 높게 나타났다.

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A study on exposure of organic solvents in manufacturing industry (제조업 산업장의 유기용제 노출에 관한 연구)

  • Moon, Deog-Hwan;Kim, Jeong-Ha;Kim, Pil-Ja;Park, Myung-Hee;Hwang, Yong-sik;Lee, Chae-Kwan;Lee, Chang-Hee
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.11 no.3
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    • pp.219-228
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    • 2001
  • Objective : For the purpose of preparing the fundamental data and health promotion and control program on organic solvents in air of manufacturing industry. Methods : The author surveyed number of organic solvent components which was used in working site and also determined the organic solvents concentration in air of 927 manufacturing industries and 1,267 working process with gas chromatography(NIOSH manual) for five years from 1995 to 1999. Results : Mean number of solvents components by type of industry, working process was number of 12. There were exceeded to TLV of 1,2-dichloroethane in textile manufacturing industry N,N-dimethyl furan in tanning and dressing of leather ; luggage, handbags, saddlery, harness and footwear manufacturing industry and chemical and chemical product manufacturing industry by type of industry. There were exceeded to TLV of 1,2-dichloroethane in handwriting and drawing process, cellosolve in adhesive spreading process, N,N-dimethly furan in production of solvent process and adhesion process by working process Total exceeded rate to threshold limit values of organic solvents mixture were 12.9% for EI(Exposure index) and 10.0% for Em(Estimation of mixture) by type of industry, 11.3% for EI and 8.2% for Em by type of working process. The highest exceed rate was 36.7% for EI in tanning and dressing of leather ; luggage handbags, saddlery, harness and footwear manufacturing industry and 29.0% for Em in textile manufacturing industry. The highest exceeded rate was 23.1% for EI and 12.5% for Em in adhesive spreading process by working process. Mean values of total subjects by type of industry and type of working process were $0.7{\pm}1.8$ for EI and $0.7{\pm}1.7$ for Em respectively. Conclusions : As above results, the author suggest that it makes the environmental control program on 1.2-dichloroethane, N,N-dimethyl furan, cellosolve by kind of organic solvent and on textile manufacturing industry, tanning and dressing of leather ; luggage, handbags, saddlery harness and footwear manufacturing industry by type of industry, and on handwriting, drawing process and adhesive spreading process and adhesion process by type of working process.

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Pedicled Deep Inferior Epigastric Perforator Flap for Treatment of Dystrophic Epidermolysis Bullosa-Associated Squamous Cell Carcinoma in the Groin - Case Report - (심부하복벽동맥 천공지 유경 피판을 이용한 이영양성 수포성 표피박리증에 합병된 서혜부 편평 세포 상피암의 치료 - 증례 보고 -)

  • Kim, Kyung-Pil;Kim, Ji-Hoon;Kim, Eui-Sik;Hwang, Jae-Ha;Kim, Kwang-Seog;Lee, Sam-Yong
    • Archives of Reconstructive Microsurgery
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    • v.19 no.2
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    • pp.97-100
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    • 2010
  • Purpose: Epidermolysis bullosa is a rare genetic disease, characterized by the presence of extremely fragile skin and formation of recurrent blister resulting from even a minor mechanical injury. Squamous cell carcinoma (SCC) is recognized as a complication of the chronic scarring associated with dystrophic epidermolysis bullosa (DEB). When a soft tissue defect happens in a patient with epidermolysis bullosa, it is difficult to cover it with a skin graft or a flap. We describe the successful use of a pedicled deep inferior epigastric perforator flap for the reconstruction of SCC associated with DEB in the groin. Methods: A 29-year-old man diagnosed with DEB at birth sustained an ulcer increasing in the right groin for the last 7 months. Under general anesthesia, the mass lesion and lymph nodes were removed and the resulting defect was covered with a pedicled deep inferior epigastric perforator flap. Results: The flap survived completely and his postoperative course was uneventful. Histopathological examination revealed a SCC in the right groin and malignant tumor cells in the removed lymph nodes as well. Additional positron emission tomogram showed a malignant lesion in the ileocecal area with regional lymph node metastasis. The patient was referred to an oncologist for chemotheraphy, but the patient refused to take it. During a 4-month follow-up period, there was no recurrence in the right groin. Conclusion: We suggest that perforator flaps can be considered as a reliable alternative for the reconstruction of soft tissue defects in a patient with DEB.

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Inhibition of Gap Junctional Intercellular Communication by Food Preservatives Potassium Sorbate (소르빈산 칼륨의 GJIC 억제로 인한 간독성 유발)

  • Hwang, Jae-Woong;Chung, Ji-Hye;Jung, Ji-Won;Jung, Ji-Youn;Kim, Sun-Jung;Park, Jung-Ran;Ahn, Ji-Yun;Ha, Tae-Youl;Kim, Sung-Ran;Lee, Yong-Soon;Kang, Kyung-Sun
    • Journal of Food Hygiene and Safety
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    • v.21 no.4
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    • pp.269-273
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    • 2006
  • Potassium Sorbate (PS) is a potassium salt version of sorbic acid, which has antimicrobial and fungistatic features in foods. Therefore, PS is used as a food preservative against fungi and mold. PS has been found to be non-toxic even when taken in large quantities given its trait to be broken down in the body into water and carbon dioxide. Gap Junctional Intercellular Communication (GJIC) is essential in the maintenance of tissue homeostasis during development and differentiation. This study was made of the effects of PS on GJIC in WB-F344 rat liver epithelial (WB) cells. We found dramatic decrease of cell viability in time- and dose-dependent manners when WB cells were treated with PS. The effect of PS on GJIC is strong inhibition, and it took place in parallel with a hyperphosphorylation of connexin 43 expression. The finding that PS interferes with gap junction functionality should be considered with respect to the mechanism of PS-induced hepatotoxicity.

Analysis of Microbiological Contamination in Kimchi and Its Ingredients

  • Lee, Ji-Hyun;Ha, Ji-Hyoung;Lee, Hae-Won;Lee, Jae Yong;Hwang, Ye-Seul;Lee, Hee Min;Kim, Sung Hyun;Kim, Su-Ji
    • Journal of Food Hygiene and Safety
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    • v.33 no.2
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    • pp.94-101
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    • 2018
  • Although Kimchi has health benefits, food poisoning associated with consumption of Kimchi has been frequently reported. Accordingly, microbiological properties of Kimchi (100 samples) and washing effects on microbial reduction against its ingredients (200 samples) were examined. Total aerobic bacteria, coliforms, Escherichia coli, Bacillus cereus, and Clostridium perfringens were quantified. In addition, B. cereus, Salmonella spp., Enterohemorrhagic E. coli, C. perfringens, Campylobacter jejuni/coli, Staphylococcus aureus, Vibrio parahaemolyticus, Listeria monocytogenes, and Yersinia enterocolitica were analysed qualitatively. Total aerobic bacteria count was approximately 1.4-9.0 log CFU/g, which were highest in ginger (8.8 log CFU/g), and Chonggak Kimchi (9.0 log CFU/g). The range of coliform counts detected in all raw materials was 0.5-7.3 log CFU/g and ginger showed the greatest number 7.3 log CFU/g among others. Contamination was decreased to 0.2-3.2, 0.3-2.7, and 1.0-3.9 log CFU/g for total aerobic bacteria, coliforms, and B. cereus, respectively, after washing. Minimising microbial contamination in Kimchi ingredients is necessary to ensure the safety of Kimchi. These results indicate that washing is a useful method to reduce bacterial contamination in Kimchi.

Influences of the Parenting Style, Peer Attachment, Relationship of Teacher factors on Learning Attitude and Life Satisfaction of Korean adolescents (청소년 시기의 부모양육방식, 또래애착, 교사관계가 학습태도 및 삶의 만족에 미치는 영향)

  • Kang, Ha-Na;Yong, Hye-Ryeon;Hwang, Hyun-Seok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.10
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    • pp.449-457
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    • 2016
  • Adolescence is a period of transition from child to adult and is a very important period in which to think about the direction to go in the future and establish one's ego. However, the level of life satisfaction experienced by Korean youths in the adolescent period has been shown to be the lowest among OECD countries. It is very critical to understand which factors are important in determining the level of life satisfaction and how they affect it. In this study, to analyze the factors which affect the life satisfaction of youths and their learning attitude - essential school activity prior to life satisfaction in the youth period, we firstly focused on the relationships with their parents, peers and teachers as potential factors affecting their learning attitude and life satisfaction. This study found that Parenting Style, Peer Attachment and Relationship with Teachers significantly influenced Life Satisfaction either directly or indirectly. We analyzed the structural relationships among these factors using the structure equation model, discussed the analysis results and concluded with further research directions.

Determination of fatty acid methyl esters (FAME) content in aviation turbine fuel using multi-dimensional GC-MS (Multi-dimensional GC-MS를 이용한 항공터빈유의 FAME 함량 분석)

  • Youn, Ju Min;Doh, Jin Woo;Hwang, In Ha;Kim, Seong Lyong;Kang, Yong
    • Journal of the Korean Applied Science and Technology
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    • v.34 no.4
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    • pp.717-726
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    • 2017
  • The current allowable cross-contamination level of fatty acid methyl esters (FAME) in aviation turbine fuel (AVTUR) is 50 mg/kg, due to that the presence of FAME in AVTUR can significantly impact the fuel supply system and jet engine. It has been difficult to analyze the level of FAME in AVTUR, since it is consisted of a lot of hydrocarbons. In this study, thus, a new method using multi-dimensional GC-MS (MDGC-MS) was proposed in order to determine the FAME level in AVTUR effectively. Applying to MDGC-MS with Deans switching system enabled us to detect and quantify the FAME with low carbon numbers such as those derived from coconut oil and palm kernel oil. The matrix effect of MDGC-MS method, which could shift the FAME peaks to slightly longer retention times, was reduced by 20 times compared with that of 1-dimensional GC-MS reference method. This developed method could be suitable for qualitative and quantitative analyses to determine the contamination level of trace FAME in AVTUR.

Improvement of Immune Activities of Rhodiola sachalinensis A. Bor. by Serial Solvent Fractionization (홍경천의 면역활성이 증진된 용매별 분획 추출물)

  • Ha, Ji-Hye;Kim, Cheol-Hee;Jeong, Hyang-Suk;Jin, Ling;Oh, Sung-Ho;Kim, Seung-Seop;Jeong, Myoung-Hoon;Ma, Choong-Je;Nam, Jong-Hyun;Hwang, Baik;Choi, Geun-Pyo;Park, Uk-Yeon;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.17 no.3
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    • pp.210-216
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    • 2009
  • This study was performed to compare the effects of immuno-modulating activities of Rhodiola sachalinensis A. Bor. fractionized by consecutive solvent separation. The Cytotoxicity of all fractionized extracts on human kidney cell (HEK293) was lower than crude extracts. Generally, the butanol and chloroform extracts showed less cytotoxicity on about 10.07% and 9.67% than the crude extracts. For human immune B and T cell growth, chloroform fraction showed the highest cell growth compared to the control. The secretion of cytokines (IL-6, $TNF-\alpha$) on human B and T cells were increased by adding chloroform extracts. Also, NK cell growth was significantly improved up to nearly 30% by adding the supernatant of B cell medium grown with the chloroform fraction. It was also found that chloroform fraction could yield higher nitric oxide production from macrophage than untreated control cells. Differentiation of HL-60 cells was increased up to 131.9% after treatment with chloroform fraction extracts, compared to the control. These results indicate that the chloroform fraction of R. sachalinensis have high immune activation activity than others fractions and the crude extracts, implying that this chloroform fractions could be used a new functional material.