• Korean Journal of Food Science and Technology
• /
• v.33 no.4
• /
• pp.451-454
• /
• 2001

Fish paste containing mushroom, Agaricus bisporus, was prepared for the supplementary value of the product, and it was tested for the color, textural properties, and sensory attributes. With increasing amounts of the mushroom in fish paste, L value decreased and a value increased in the color changes while the b value was not significantly different. As the result of textural properties, folding test in all test samples showed AA that mean good flexibility. The hardness, elasticity, gumminess and brittleness of fish paste with the mushroom were increased but the strength was not significantly different. In overall acceptance of sensory evaluation, fish paste containing 10% of mushroom received the highest score. These results suggest that Agaricus bisporus can be applied to fish paste for the purpose of the varieties of product.

• Journal of Korean Society for Atmospheric Environment
• /
• v.22 no.3
• /
• pp.353-360
• /
• 2006

This study identified a particle size distribution (PSD) of fine particulate matter and emission characteristics of V and Ni by the comparison between anthropogenic sources of oil combustion (industrial boiler, oil power plant, etc.) and lab-scale combustion using a drop-tube furnace. In oil combustion source, the mass fraction of fine particles (less than 2.5 micrometers in diameter) was higher than that of coarse particles (larger than 2.5 micrometers in diameter) in $PM_{10}$ (less than 10 micrometers in diameter) as like in lab-scale oil combustion. In addition to this, it was identified that ultra-fine particles (less than 0.1 micrometers in diameter) had a large distribution in fine particles. Toxic metals like V and Ni had large mass fractions in fine particles, and most of all was distributed in ultra-fine particles. Most of ultra-fine particles containing toxic metals have been emitted into ambient by combustion source because it is hard to control by the existing air pollution control device. Hence, we must be careful on these pollutants because it is obvious that these are associated with adverse health and environmental effect.

• Journal of Microbiology and Biotechnology
• /
• v.9 no.4
• /
• pp.450-456
• /
• 1999

A high molecular-weight water-soluble fraction(PO) obtained by the ethanol precipitation of 0.1 N NaOH extracts of the mushroom Pleurotus ostreatus showed 82% anti-complementary activity for complement consumption hemolysis. The PO consisted of 42% carbohydrate (w/w), 50% protein (w/w), and 3% uronic acid (w/w). Fifty-eight percent of the anti-complementary activity decreased by periodate oxidation and 22% by protease digestion, suggesting that the sugar and protein moieties are essential for this activity. Two polysaccharide fractions, PO-IIIa-1 and PO-IIIa-2, with anti-complementary activity were isolated from the PO using DEAE-Sepharose FF followed by Sephadex G-75 and Sepharose CL-6B gel permeation chromatographies. The PO-IIIa-2 was found by HPLC to be nearly homogeneous, with the molecular mass of 531 kDa, and showed 96% $ITCH_{50}$ (inhibition against the total complement hemolysis of deionized water as the control) at a concentration of 1 mg/ml. This fraction contained galactose, mannose, fucose, and glucose with molar ratios of 1.75:1:0.65 and 0.59, respectively. The majority of galactose and mannose units in the PO-IIIa-2 were composed of TGalp1 ->, ->6Galp1->, ->2,6Galp1->, and ->Manp1->. The PO-IIIa-1 (molecular mass of 2000 kDa), exhibiting higher activity than the PO-IIIa-2, was further purified into two fractions, unbound proteoglycan (PO-IIIa-1A) and bound glucomannan (PO-IIIa-lB), by affinity chromatography using ConA-Sepharose CL-4B. The anti-complementary activity of each affinity purified fraction decreased as compared to that of the native PO-IIIa-1 fraction, indicating that the formation of complex between both polysaccharide fractions was necessary for full anti-complementary activity.

• The Journal of Internal Korean Medicine
• /
• v.39 no.4
• /
• pp.699-707
• /
• 2018

Objectives: This study was designed to investigate characteristics of digital infrared thermal imaging (DITI) and quantitative evaluations in patients with burning mouth syndrome (BMS). Methods: We reviewed the clinical records of 38 patients with BMS who visited the Oral Diseases Clinic of Kyung Hee University Korean Medicine Hospital from March 1st, 2018 to June 30th, 2018. The subjects were evaluated with digital infrared thermal imaging (DITI) and for heart rate variability (HRV), unstimulated salivary flow rate (USFR), and the proportion of coated tongue. Results: Most patients showed higher temperatures on the central part of the tongue (T2) than on the middle of the forehead (T1). The patients tended to have a high Low frequency/High frequency (LF/HF) ratio. Statistically significant negative correlations were noted between the age of patients and the temperature of T1 and T2. Statistically significant negative correlations were also observed between the LF/HF ratio and 'T1-T2' values. Conclusions: This study suggests that DITI and HRV are useful for the validation of patients with BMS. Correlations between the result values suggest that sympathetic function acceleration is related to temperature distribution and, ultimately, to symptoms.

• Biomolecules & Therapeutics
• /
• v.5 no.2
• /
• pp.187-193
• /
• 1997

The in vivo and in vivo antibacterial activity of DW-116, a newly synthesized fluoroquinolone, were compared with those of other quinolones. DW-116 exhibited more potent antibacterial activity than rufloxacin and lower activity than ofloxacin and ciprofloxacin in in vivo assay But, DW-116 particularly showed strong activity against the family of staphylococci including methicillin-sensitive staphylococcus and its activity was more active than that of ciprofloxacin. The time-kill curve studies showed rapid bactericidal activity for DW-116. The post-antibiotic effect of DW-116 was observed between 0.66 and 5 hours. The therapeutic efficacy of DW-116 against respiratory infection with P. aeruginosa was as strong as that of ciprofloxacin and its effect against urinary tract in(traction with E. coli was more effective than rufloxacin. The excellent therapeutic efficacy of DW-116 against these local infections is due to its good pharmacokinetic profiles.

• The Korean Journal of Applied Statistics
• /
• v.21 no.1
• /
• pp.159-168
• /
• 2008

Since the term structure of interest rates (TSIR) has longitudinal data, we should consider as input variables both time left to maturity and time simultaneously to get a more useful and more efficient function estimation. However, since the resulting data set becomes very large, we need to develop a fast and reliable estimation method for large data set. Furthermore, it tends to overestimate TSIR because data are correlated. To solve these problems we propose a mixture of weighted least squares support vector machines. We recognize that the estimate is well smoothed and well explains effects of the third stock market crash in USA through applying the proposed method to the US Treasury bonds data.

• International Journal of Industrial Entomology and Biomaterials
• /
• v.31 no.1
• /
• pp.14-19
• /
• 2015

In a previous report, we identified several candidate antimicrobial peptides through de novo RNA sequencing of the centipede Scolopendra subspinipes mutilans. Here, we identify and characterize one of these peptides, Scolopendrasin I. We identified the centipede antimicrobial peptide Cecropin from the centipede transcriptome using an SVM algorithm, and subsequently analyzed the amino acid sequence for predicted secondary structure using a GOR algorithm. We identified an alpha helical region of Cecropin and named it Scolopendrasin I. We then assessed antimicrobial and hemolytic activity of Scolopendrasin I. Scolopendrasin I showed antimicrobial activity against various microbes, including antibiotic-resistant Gram-negative bacteria, in a radial diffusion assay. Scolopendrasin I had potent antibacterial activity against acne-associated microbes in a colony count assay and showed no hemolytic activity in a hemolysis assay. In addition, we confirmed that Scolopendrasin I bound to the surface of bacteria via a specific interaction with lipoteichoic acid and lipopolysaccharide, two components of bacterial cell membranes. In conclusion, the results presented here provide evidence that this is an efficient strategy for antimicrobial peptide candidate identification and that Scolopendrasin I has potential for successful antibiotic development.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2009.05a
• /
• pp.1136-1140
• /
• 2009

지상강우 관측망을 이용한 강우량 측정의 대안으로서 사용되는 기상 레이더를 활용한 강우량 추정의 경우, Z-R 방정식을 이용하여 반사도를 강우량으로 환산하는 방법을 일반적으로 사용한다. 이때 발생하는 각종 오차는 레이더 장비가 가지는 기계적인 오차뿐만 아니라 Z-R 방정식이 가지는 오차 등이 있으며, 이를 보정하기 위해서 레이더를 활용하여 추정된 강우량에 지상강우량계와 레이더강우량과의 비율인 G/R비를 보정하는 방법을 일반적으로 사용한다. 본 연구에서는 이와 같이 레이더 강우량을 보정하기 위해서 사용되는 G/R비를 산정하는데 미치는 지형적인 효과를 고려하기 위해서 광덕산 레이더 유효범위 100km 내(군사분계선 이북 미포함)의 지역에 대하여 군집분석을 실시하여 크게 산악지역과 평야지역으로 구분하고, 각각 구분된 지역에 대하여 G/R 비를 산정하여 초기추정 레이더 강우량에 곱하는 mean-field bias 보정을 실시하였다. 광덕산 레이더 기상관측소의 유효범위 100km 내의 2007년, 2008년 홍수기(6/21${\sim}$9/20)기간 동안 94개 Automatic Weather Station(AWS)지점에 대하여 크게 산악지역과 평야지역으로 지역화 시키는 방법은 비계층적 군집분석 기법 중 fuzzy-c mean 방법을 적용하였다. 또한 광덕산 레이더 반사도 기본 자료는 차폐영역으로 생기는 반사도 데이터 누락을 보완하기 위하여 0도와 1.5도 sweep 합성 10분단위 uf 자료를 사용하였으며, AWS와 보정이 이루어지는 레이더 격자의 크기는 최대 4km${\times}$4km로 선정하였다. 본 연구에 있어서 검증방법은 지역을 구분하기 전과 후를 AWS 실측 관측값과 절대상대오차, 평균제곱근 오차로써 비교하였다.

• Journal of Korean Public Health Nursing
• /
• v.28 no.3
• /
• pp.522-535
• /
• 2014

Purpose: This study was constructed in order to examine factors that influence work-related musculoskeletal disease (WMSD) approvals and current status according to the company size. Method: This is a descriptive study that utilized Industrial Accident Compensation Claim Data. Workplaces with over 35,811 workers derived from the 2012 claim data, which comprised approximately 91.5%, were selected for this study. Then workplaces were divided into three groups according to the number of workers: less than 5, 5~299, and 300 and over. Results: Since 2008, the number of small sized workplaces has increased. The 2012 data showed that 32.5% of workers at small sized workplace had WMSD. However, workplaces with 5~299 workers showed WMSD approval rate of 60%. Of note most WMSD approved workers were employed by manufacturing and construction companies, regardless of the workplace size. Most of them were engaged in elementary tasks. The days of medical treatment at OPD and IPD were most prevalent among workers at the largest workplaces. Conclusions: It is certain from this study that WMSD has been polarized by the company size. More policy attention should be paid to the WMSD status of workers at small sized workplaces which usually do not have their own health office.

• Journal of Korean Neurosurgical Society
• /
• v.44 no.4
• /
• pp.185-189
• /
• 2008

Objective : The authors present their experiences with stereotactic multiplanar reformatted (MPR) computed tomography (CT)-guided catheter placement for thrombolysis of spontaneous intracerebral hematoma (sICH) and their clinical results. Methods : In 23 patients with sICH, MPR CT-guided catheter placement was used to select the trajectory and target point of hematoma drainage. This group was comprised of 11 men and 12 women, and the mean age was 57.5 years (range, 31-79 years). The patients' initial Glasgow Coma Scale scores ranged from 7 to 15 with a median of 11. The volume of the hematoma ranged from 24 mL to 86 mL (mean 44.5 mL). A trajectory along the main axis of the hematoma was considered to be optimal for thrombolytic therapy. The trajectory was calculated from the point of entry through the target point of the hematoma using reformatted images. Results : The hematoma catheter was left in place for a median duration of 48.9 hours (range 34 to 62 hours). In an average of two days, the average residual hematoma volume was 6.2 mL (range 1.4 mL to 10.2 mL) and was reduced by an average of 84.7% (range 71.6% to 96.3%). The residual hematoma at postoperative seven days was less than 5 mL in all patients. There was no treatment-related death during hospitalization. Conclusion : The present study indicates that stereotactic MPR CT-guided catheter placement for thrombolysis is an accurate and safe procedure. We suggest that this procedure for stereotactic removal of sICH should be considered for the optimization of the trajectory selection in the future.