• Proceedings of the Korean Society of Toxicology Conference
• /
• 2001.10a
• /
• pp.85-86
• /
• 2001

Indole-3-carbinol (I3C), one component of cruciferous vegetables (the Family of Cruciferae), has been shown to exert chemopreventive effects in liver, colon and mammary tissue, but there has been substantial evidence that consumption of I3C induces tumor promotion in some tissues. Our studies were investigated to examine the modifying effects of I3C in the 7, 12-dimethylbenz［a］anthracene (DMBA) induced rat mammary tumor model.(omitted)

• Korean Journal of Veterinary Research
• /
• v.49 no.2
• /
• pp.121-125
• /
• 2009

Paratuberculosis caused by Mycobacterium avium subspecies paratuberculosis (Mpt) is a chronic infectious enteric disease with deleterious impact on the performance in ruminants. In Korea, ELISA has been introduced to detect antibodies to Mpt in individual cattle. However, comparison study with ELISA has not been studied until now. In total, a panel of 899 serum samples obtained from dairy cattle was analyzed with two commercial ELISAs for Mpt to assess the performance. Two ELISAs employed in this study were both licensed worldwide. Two ELISAs applied onto same serum samples showed the moderate agreement (kappa value = 0.60). There was non-significant McNemar test (p = 0.0614) between two ELISA results indicating that each proportion detected by two kits did not differ. In addition, the percent agreement between two ELISA results was turned out to be 96.8% which interpreted excellent reproducibility. It was shown from this study that two ELISAs revealed moderate kappa agreement performance. The implication raised is that when ELISAs as diagnostics are used to detect Mpt in individual cattle, positive reaction by either ELISA should be interpreted as serologically Mpt positive due to presumed low sensitivity of ELISAs and their test agreement being less than 100%.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.40 no.2
• /
• pp.183-189
• /
• 2020

This paper presents an experimental investigation regarding the sensitivity of electrical impedance of a steel wire to tensile stress, ambient temperature and induced frequency. For various stress levels and temperatures, the electrical impedance of a steel wire has been measured on a self-sensing system. The three experimental cases are carried out at various temperature conditions, stress levels and applied frequencies. If the temperature increases and stress level decreases at a given frequency, the electrical impedance on the steel wire increases. The results show that the correlation between electrical impedance and temperature is a linear relationship at all stress levels. It is noted that the sensitivity of impedance to temperature is much higher than the stress.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2012.10a
• /
• pp.522-527
• /
• 2012

This paper presents a result of the mechanical noise and vibration analysis as well as the electrical characteristics analysis of the permanent magnet (PM) motor according to the driving method that is Brushless DC (BLDC) drive and Brushless AC (BLAC) drive. To do that, the characteristics of the PM motor, which have the same output power but different driving method, are investigated. At that time, the characteristics such as torque, torque ripple and flux density, and so on, are obtained by finite element analysis (FEA). Besides, noise and vibration are obtained by spectrum analysis. The magnetic noise is defined as noise generated from vibrations due to electromagnetic excitation force. In this paper, the electromagnetic excitation force is analyzed and design process of noise reduction is proposed. Finally, The validity of the analysis results is verified by test.

• Journal of the Korean Institute of Telematics and Electronics
• /
• v.22 no.3
• /
• pp.60-67
• /
• 1985

A new glut bel routing technique for gate array is described in this paper. In former global routers the position of pins is considered to be in the center of the cell. So it is impossible to exactly estimate the number of signal lines passing through each channel. As a result, an overflow occurs and the overflow violates 100% wiring in detailed routing pro-cesses. Besides this, there are some problems in former global routers, for example, design time and cost, etc. This paper proposed a new algorithm in which pins ordering is considered to solve these problems. Using this algorithm, a global router is developed. Program experiments show the efficiency of the proposed algorithm.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.21 no.1
• /
• pp.113-120
• /
• 2008

Objective : The purpose of this study was to explore the correlation between efficacy and various factors of the acne patients. Method : We reviewed 30 acne patients who visited Allergy/Derma-cosmetic Clinic at Kyung Hee Neo Medical Center from June, 2006 to December, 2007 and were treated with herbal medicine and acupuncture for 4 weeks. We investigated premenstrual aggravation of acne, facial burning sensation, constipation, Heart Rate Variability(HRV) results and regional distribution of acne. And we evaluated inflammatory acnes according to the Korean Acne Grading System(KAGS). Results & Conclusions : 1. The average age of total patients was 23.0 years old. The most frequent age group was 21-25 years old. Patients evaluated as KAGS Grade 2 were most common. 2. In total patients, inflammatory acne were reduced significantly after 4 weeks of treatment. 3. The result of analysis on premenstrual aggravation of acne, facial burning sensation and constipation, there weren't any difference of treatment results on statistical meaning. 4. The results show that there were significant correlations between the Low Frequency at HRV and the rate of acne reduction. (Pearson correlation = -0.565) 5. If the distribution of acne did not involve the T-zone of the face, chest, or back of the body, inflammatory acne were significantly decreased after 4 weeks of treatment.

• The Korean Journal of Physiology and Pharmacology
• /
• v.15 no.3
• /
• pp.123-128
• /
• 2011

Caesalpinia sappan (C. sappan) is a medicinal plant used for promoting blood circulation and removing stasis. During a screening procedure on medicinal plants, the ethylacetate extract of the lignum of C. sappan (CLE) showed inhibitory activity on arginase which has recently been reported as a novel therapeutic target for the treatment of cardiovascular diseases such as atherosclerosis. CLE inhibited arginase II activity prepared from kidney lysate in a dose-dependent manner. In HUVECs, inhibition of arginase activity by CLE reciprocally increased NOx production through enhancement of eNOS dimer stability without any significant changes in the protein levels of eNOS and arginase II expression. Furthermore, CLE-dependent arginase inhibition resulted in increase of NO generation and decrease of superoxide production on endothelium of isolated mice aorta. These results indicate that CLE augments NO production on endothelium through inhibition of arginase activity, and may imply their usefulness for the treatment of cardiovascular diseases associated with endothelial dysfunction.

• The Korean Journal of Physiology and Pharmacology
• /
• v.11 no.3
• /
• pp.135-138
• /
• 2007

Hypertonicity imposes a great deal of stress to cells since it causes rise in cellular ionic strength, which can be reduced by the accumulation of compatible osmolytes. TonEBP plays a central role in the cellular accumulation of compatible osmolytes via transcriptional stimulation of membrane transporters and aldose reductase. Alternatively spliced forms of TonEBP mRNA have previously been reported and two of them showed different transcriptional activity. In the present study, isoform-specific antibodies were produced to confirm the translation of the spliced mRNA to protein. TonEBP was immunoprecipitated by using anti-TonEBP antibody and then immunoblotted using anti-TonEBP or isoform specific antibodies to find out the expression profile of TonEBP isoforms in basal or stimulated condition. From these results, we conclude that all TonEBP isoforms are expressed in mammalian cells and their expression patterns are not same in every cells.

• Journal of architectural history
• /
• v.18 no.1
• /
• pp.51-65
• /
• 2009

The inner gate(The last gate inside a temple, facing the main hall) is not a well-known part in the temple construction of Joseon. This study is focused on seeking truth about the inner gate arrangement of the existing temples as well as proving that it has changed while maintaining a certain relationship with the gate-pavilion arrangement. The inner gate is related to the Cheondo ritual which is letting the dead people's spirits go to heaven, mainly performed in Buddhism, and it has been demonstrated that the inner gate has gradually disappeared as the importance of gate-pavilions has been emphasized along with the changes of the ritual. The inner gate was a common construction before the 18th Century but since that time, it has gradually disappeared and finally it faced the main hall as the gate-pavilion and made the 4 halls-centered arrangement with the temple dormitories on both sides.

• Journal of Haehwa Medicine
• /
• v.14 no.1
• /
• pp.167-177
• /
• 2005

In oriental medicine, Ostericum koreanum Radix & Aralia contientalis Radix are frequently used materials for strenthing lumbar and knees. Bang-Yak-Hap-Pyun(方藥合編) is widely used for clinical herbal prescription book. In Bang-Yak-Hap-Pyun, Ostericum koreanum Radix is used 1.2g~6g. and Aralia contientalis Radix is used 1.6g~4.8g. The most important fact is that the prescription used Ostericum koreanum Radix & Aralia contientalis Radix at the same time is 11. The number of prescription Ostericum koreanum Radix & Aralia contientalis Radix in Bang-Yak-Hap-Pyun is total 41. 5 in sang-tong(上統), 22 in jung-tong(中統), 14 in ha-tong(下統). The group of mostly used disease is about low back pain, knee pain, C.V.A., facail palsy, commom cold, numbness. The ratio of Ostericum koreanum Radix in Bang-Yak-Hap-Pyun is 3.03%~15.63%. And the ratio of Aralia contientalis Radix is 3.57%~12.00%. The mostly quoted medical literature what prescription included Ostericum koreanum Radix & Aralia contientalis Radix in Bang-Yak-Hap-Pyun is Dong-Yi-Bo-Gam. Man-Byeong-Hoi-Choon, and Hwa-Je-Gook-Bang.