• Title/Summary/Keyword: Humidity stability

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Effects of Temperature and Relative Humidity on Fat Soluble Vitamin Contents in Commercial Vitamin Tablet (저장 온도 및 상대습도가 비타민 정제 중 지용성 비타민 함량의 변화에 미치는 영향)

  • Kim, Dong-Seob;Lee, Jae-Hwang;Kim, Sae-Gon;Lee, Dong-Un;Park, Seok-Jun;Lee, Jin-Hee;Lee, Kang-Pyo;Choi, Sung-Won;Baik, Moo-Yeol
    • Applied Biological Chemistry
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    • v.49 no.2
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    • pp.103-107
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    • 2006
  • Effects of temperature and relative humidity on fat soluble vitamin contents in two commercial vitamin tablets ('Multivitamin Dandelion' and 'vitamin E Yarrow') were investigated. When they stored at different temperature (25, 35, and $45^{\circ}C$) with cap and stored at low relative humidity (11% RH) without cap, all fat soluble vitamins (vitamin A acetate, vitamin E acetate and vitamin E) were stable during 24 weeks of storage period. However, when they stored at high relative humidity (75% RH and 100% RH) without cap, vitamin A acetate and vitamin E acetate dramatically disintegrated at the early stage of storage. On the other hand, vitamin E gradually decreased during storage. Therefore, stability of some fat soluble vitamins, which exist as acetate form, was highly dependent on relative humidity rather than storage temperature. Water may act as a plasticizer and increased the mobility of molecules in vitamin tablet resulting in relatively fast disintegration of some fat soluble vitamins.

Preparation of Humidity Sensor Using Novel Photocurable Sulfonated Polyimide Polyelectrolyte and their Properties (광가교성 Sulfonated Polyimide 전해질 고분자를 이용한 습도센서의 제조 및 특성 분석)

  • Lim, Dong-In;Gong, Myoung-Seon
    • Polymer(Korea)
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    • v.36 no.4
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    • pp.486-493
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    • 2012
  • Photocurable sulfonated polyimide (SPI) polyelectrolyte containing chalcone group was prepared and fabricated on an alumina electrode pretreated with chalcone-containing silane-coupling agent. SPI films with bis(tetramethyl)ammonium 2,2'-benzidinedisulfonate ($Me_4N$-BDS)/4,4'-diaminochalcone (DAC)/pyromellitic dianhydride (PA)= 90/10/100 possessed very linear response(Y = -0.04528X+7.69446, $R^2=0.99675$) and showed resistance changing from 4.48 to $2.1k{\Omega}$ between 20 and 95 %RH. The response time for absorption and desorption measurements between 33 and 94 %RH% was about 79 s, which affirmed the high efficiency of crosslinked SPI film for rapid detection of humidity. A negative temperature coefficient showing $-0.49%RH/^{\circ}C$ was found and proper temperature compensation should be considered in future applications. Moreover, pretreatment of the substrates with chalcone-containing silane-coupling agent was performed to improve the water durability and the stability of the humidity sensors at a high humidity and a high temperature and long-term stability for 480 h. The crosslinked SPI films anchored to electrode substrate could be a promising material for the fabrication of efficient humidity sensors with superior characteristics compared to the commercially available sensors.

Self-Curable Humidity-Sensitive Polyelectrolytes Attached to the Alumina Substrate for the Humidity Sensor and their Stability in Water (알루미나 기재에 부착된 습도센서용 자기 가교형 감습성 전해질 고분자의 내수성)

  • Han, Dae-Sang;Gong, Myoung-Seon
    • Polymer(Korea)
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    • v.34 no.4
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    • pp.313-320
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    • 2010
  • New cinnamate group-containing copolymers for a self-curable, humidity-sensitive polyelectrolyte and polymeric anchoring agents were prepared by copolymerization of [2-[(methacryloyloxy) ethyl]dimethyl]propyl ammonium bromide(MEPAB), methyl methacrylate(MMA), 3-(trimethoxysilyl) propyl methacrylate(TMSPM) and 2-(cinnamoyloxy)ethyl methacrylate(CEMA). Photocrosslinkable copolymer composed of MEPAB/MMA/TMSPM/CEMA=70/20/0/10 were used for humidity-sensitive membrane, and those of 50/0/20/30 and 0/0/50/50 were used for polymeric anchoring agents. 3- (Triethoxysilyl)propyl cinnamate(TESPC) was also used as a surface-pretreating agent for the comparison of capability of attachment of polyelectrolyte to the electrode surface with polymeric photocurable silanecoupling agents. Pretreatment of the electrode substrate with anchoring agents was performed to form a cinnamate thin film on the electrode through covalent bonds. When the sensors were irradiated with UV light, the anchoring of a polyelectrolyte into the substrate was carried out via the [2$\pi$+2$\pi$] cycloaddition. The resulting sensors using polymeric anchoring agents and TESPC showed water durability with increase of resistance by 60~85%, which is corresponding to the reduction of 2.25~3.15%RH, after soaking in water for 24 h. They showed good hysteresis (-0.2%RH), response time (90 sec) and long-term stability at high temperature and humidity.

Stability of Atenolol Tablet After Dispensing to Powder form at Community Pharmacies (근린약국에서 산제로 조제된 아테놀올정의 안정성)

  • Yong, Chul-Soon;Choi, Han-Gon;Rhee, Jong-Dal;Yoo, Bong-Kyu
    • Journal of Pharmaceutical Investigation
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    • v.34 no.4
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    • pp.299-303
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    • 2004
  • Prescription filling in powder form is performed in community pharmacy practice to adjust dose for children and patients who cannot swallow whole tablet. However, there are few reports regarding the stability of the active ingredient and possible microbial growth after the medication is dispensed to powder form. This study examined the stability of atenolol, an antihypertensive agent, and microbial growth in the unit dose pouches dispensed at twenty-one community pharmacies located in Taegu area. Randomly chosen first unit dose pouch contained 77.4% of the prescribed dose of the drug and there were only four community pharmacies that dispensed the drug within 10% deviation from the dose prescribed by physician. Surprisingly, there were three community pharmacies that dispensed the drug with greater than 40% deviation, which may pose a major concern regarding the efficacy and safety of the drug prescribed for the treatment of hypertension. Atenolol content during a month did not indicate significant change, showing 5.4%, 4.3%, and 3.3% of decrease in 50%, 80%, and 90% relative humidity conditions, respectively. Microbiological examination during a month showed less than 0.5 microorganism in high power field (hpf) in all the relative humidity conditions tested. Based on this study, pharmacy practice in community pharmacy needs to be rigorously regulated to ensure that the dose of the prescribed drug is properly incorporated into the unit dose pouch dispensed as powder form.

Dimensional Change of Acetylated Softwood (아세틸화 침엽수재의 치수변화 특성)

  • Han, Gyu-Seong;Cho, Nam-Seok
    • Journal of the Korean Wood Science and Technology
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    • v.24 no.4
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    • pp.40-46
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    • 1996
  • It is well-known fact that dimensional stability of wood is greatly enhanced by acetylation of wood. This dimensional stability results from bulking of the reacted acetate within the cell wall, which reduces further swelling when the modified woods corne into contact with water or water vapor. The purpose of this research was to determine the water absorption and dimensional stability of the acetylated solid wood in liquid water and in humidity tests. Radiata pine, Siberian larch, and Japanese larch were acetylated. Antiswelling efficiency(ASE) and equilibrium moisture content(EMC) of acetylated wood, at 95% RH and $20^{\circ}C$ after 4weeks, was quite dependent on WPG, but was not dependent on species.

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Sensing Behavior and Long-Term Stability of Polyaniline Sensor Coated with Poly(vinylidenefluoride) for Methanol Vapors (폴리비닐리덴플루오라이드로 코팅한 폴리아닐린센서의 메탄올에 대한 감응 특성과 장기안정도 고찰)

  • Sohn Sung-Ok;Kim Jung-Suk;Huh Jeung-Soo
    • Korean Journal of Materials Research
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    • v.14 no.4
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    • pp.260-264
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    • 2004
  • The problem of polyaniline (PANi) sensor has been poor mechanical and chemical stability under atmosphere condition. In order to overcome these problems, the PANi sensor coated with polyvinylidenefluoride ($PVF_2$) was employed. The morphology of $PVF_2$ coated-PANi layer was showed smooth and transparent properties at 15% concentration of coating solution. The resistance of $PVF_2$ coated-PANi was kept at constant value and had a good stability at long-term periods in presence of humidity.

Improvement of Electrical Property and Stability of Silver Nanowire Transparent Electrode Via Ion-beam Treatment (이온빔 처리를 통한 은나노와이어 전극의 전기적 특성과 안정성 향상)

  • Jung, Sunghoon;Lee, Seunghun;Kim, Do-Geun
    • Journal of the Korean institute of surface engineering
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    • v.50 no.6
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    • pp.455-459
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    • 2017
  • The development of flexible transparent electrode has been paid attention for flexible electronics. In this study, we have developed transparent electrode based on silver nanowires with improved electrical property and stability through ion-beam treatment. The energetic particles of ion-beam could sinter junctions of each silver nanowires and etch out polyvinylpyrollidone(PVP) coated on silver nanowires. The sheet resistance of silver nanowire transparent electrode was reduced by 74%, and the resistance uniformity was increased about 3 times after exposure of ion beam. Moreover, the stability at $85^{\circ}C$ of temperature and 85% of relative humidity could be also improved.

Phamaceutical Studies on the Drug (III) -Enhancement of Dissolution and Stability of Sulfamethoxazole by ${\beta}-Cyclodextrin$ Complexation- (약물의 약제학적 연구(제 3보) -${\beta}-$시클로덱스트린과의 복합체 형성에 의한 설파메톡사졸의 용출 및 안정성 향상-)

  • Lee, Hyeon-Jong;Kim, Soo-Uck;Seo, Seong-Hoon
    • Journal of Pharmaceutical Investigation
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    • v.18 no.4
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    • pp.181-186
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    • 1988
  • Inclusion complex of sulfamethoxazole with ${\beta}-cyclodextrin$ was prepared by freeze-drying method in molar ratios of 1:1, 1:1.25, 1:1.5 and 1:1.75, and the complex formation was identified by ultraviolet and infrared spectroscopies, powder X-ray diffractometry and differential scanning calorimetry. Dissolution rate and solid state stability of the complex were investigated in comparison with those of sulfamethoxazole powder and the physical mixture of sulfamethoxazole with ${\beta}-cyclodextrin$. As a result, the dissolution rate and the stability of solid complexes in various relative humidity conditions increased more remarkably than those of sulfamethoxazole powder and physical mixture. But the difference according to molar ratio of the complex was not recognized.

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A Study on the Way to Increase Heat Resistance of Teflon Type Thin Film Electret Applied for Industrial Sensor (산업용 센서에 사용하는 Teflon계 박막 일렉트렛의 내열성 향상에 관한 연구)

  • 김병수;이덕출
    • Journal of the Korean Society of Safety
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    • v.18 no.3
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    • pp.60-63
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    • 2003
  • For the increase the charge stability of teflon electrets for used at uncomfortable industrial circumstances with high temperature or humidity, We made an investigation into double layer effect of teflon electrets. Teflon AF film was spincoated on FEP film and then the charge storage property of AF/FEP dual film was investigated to be compared with FEP film. It was found that the AF/FEP dual film has higher surface potential than FEP film on the repeated charging and annealing process. It seems that AF/FEP dual film has higher thermal stability than FEP film through TSC measurement. If the investigations of the double layer effect of Teflon film carried out more closely with it's molecular structures and surface conditions, it may be effectively improved the stability of charge storage.

Emulsion Properties of Casein-Alginate Mixtures (카제인-알긴산 혼합물의 유화특성)

  • 황재관;최문정;김종태
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.26 no.6
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    • pp.1102-1108
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    • 1997
  • Proteins and polysaccharides confer distinct functional properties in food systems. This research was attempted to improve emulsion properties of casein by protein-polysaccharide conjugation, in which alginates with various molecular weights were employed as polysaccharide sources. Casein-alginate mixtures were conjugated by the amino-carbonyl or Maillard reaction at 6$0^{\circ}C$ and 79% relative humidity. The resulting casein-alginate conjugates were tested for their emulsion activity and emulsion stabilizing properties. In general, the emulsion stability of casein-alginate mixture greatly increased due to the amino-carbonyl reaction between casein and alginates, whose magnitude depended on the molecular weight of alginate, weight ratio of casein to alginate and incubation time. It was also found that thermal stability and pH stability were markedly improved by the casein-alginate conjugation.

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