• The Journal of the Convergence on Culture Technology
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• v.8 no.6
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• pp.899-904
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• 2022

As the world becomes an aging society due to a decrease in the birth rate and an increase in life expectancy, a system for health management of the elderly population is needed. Among them, various studies on occupancy and activity types are being conducted for smart home care services for indoor health management. In this paper, we propose a random forest model that classifies activity type as well as occupancy status through indoor temperature and humidity, CO2, fine dust values and UWB radar positioning for smart home care service. The experiment measures indoor environment and occupant positioning data at 2-second intervals using three sensors that measure indoor temperature and humidity, CO2, and fine dust and two UWB radars. The measured data is divided into 80% training set data and 20% test set data after correcting outliers and missing values, and the random forest model is applied to evaluate the list of important variables, accuracy, sensitivity, and specificity.

• Journal of the Korean Society of Earth Science Education
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• v.14 no.1
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• pp.21-32
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• 2021

The recognition for future global environment was studied targeting the university students who will be grown as general public composing our society in this study. The rate recognizing as the complex space of natural objects and artifacts is very low for non-science majored university students. Also, the rate recognizing global environment change from now to the future as negative. The environment recognition should be changed as that the university students can imagine the human live together with the nature in the image of future global environment. The environment education find out and practice the method that human can co-exist together to the direction of co-exist with the nature. Also, the rate internalizing future global environment as the space the human amends for non-science majored university students. This result is interpreted as shown the point of view that the global environment can be improved by the human activity, and it suggests the direction of environment education the university should supply. The environment education direction should be converted from the eduction of environment or the eduction from environment to the education for environment. The opportunity for global environment education should be provided to all university students without the discrimination on the major in the university education course. Sustainable global environment eduction is necessary for our son and daughter live on the earth continuously.

• Journal of Sasang Constitutional Medicine
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• v.4 no.1
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• pp.5-29
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• 1992

In this study, the author researched the process in which the philosophical basis of 'Sa Sang Medicine (四象醫學)' and its methodology build up the principles of Sa Sang Medicine, and then, examined how the principles were applied to the theoretical system of Sa Sang Medicine. The conclusion would be summarized as follows. 1. 'Nae Kyung Medicine (內經醫學)' was developed under the concept that the cosmos's order and its moving rule could be directly applied to that of human body, which corresponded to the 'Theory of Hwang-No (黃老之學)'. On the contrary, Sa Sang Medicine is a thoroughly human-oriented theory formed in the Confucianism system. 2. Lee Jae-Ma's Substantialism can be briefed into 'Mind 心' (Tae Keuk 太極), 'Mind-Body 心身' (Yang Eui 兩儀) and 'Activity-Mind-Body-Matter 事心身物' (Sa Sang 四象), which respectively represents one-elemented substance, two-elemented substance and four-elemented substance. Especially, Sa Sang was used as a basic framework in which he recognized all the objects and phenomena. So, most critical significance of his substantialism consists in the intention of Sa Sang type classifying. 3. By the method of Sa Sang type classifying, Lee Jae-Ma not only redefined the main concepts of confucianism and developed a unique philosophy of his own, but also, in the field of medical science, resystemized and re-explained the structure and function of human body. 4. From the recognition that Activity-Mind-body-Matter (Sa Sang) are four different existence forms of energy 氣 (or four variation types of energy), Yi Jae-Ma thinks that the viscera of human body have a vertical structure of 'four parts 四焦' (upper, mid-upper, mid-lower and lower parts) and its physiological function is operated by the rising and falling action of four energy presentations (sorrow 哀, anger 怒, joy 喜 and pleasure 樂). 5. In "Gyuk Chi Go 格致藁", Lee Jae-Ma understood the concept of joy, anger, sorrow and pleasure on the basis of nature-emotion theory 性情論 from the philosophical viewpoint. But, from the medical viewpoint of "Dong Eui Su Se Bo Won 東醫壽世保元", he understood them on the basis of vital energy theory. That is, sorrow, anger, joy and pleasure are expression of advance or reverse of nature vital-energy 性氣 and emotion vital-energy 情氣. 6. The rising and falling action principle of four energy presentations (sorrow, anger, joy and pleasure) which produces and helps each other is an identical principles of Sa Sang Medicine, distinguished from the Oh-Haeng 五行 circulating principle in Nae Kyung Medicine. Through this principle, Lee Jae-Ma explained the viscera physiology of human body, pathology & diagnosis and pharmacology.

• The Journal of the Korea Contents Association
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• v.17 no.2
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• pp.105-112
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• 2017

This study recognizes it as a social problem that can be prevented by basic research on safety security design for the elderly, and aims to clearly analyze risk factors for injury. For this study, raw data from the 6th Korean National Health and Nutrition Survey were employed and analyzed. Their social characteristics were classified with standards including gender, education, EuroQoL(human locomotion, normal activity and pain uncomfortableness), the quality of life(PHQ-(1)(2)(4)), recognition on stress, activity restriction status and associated causes(bone fracture and joint injury). Their epidemiological traits were chronic diseases, 'diabetes and hip-joint pain', and health-behavioral traits were 'smoking, breakfast frequency and high-level physical activity status.' In conclusion, it can be found that damage risk of elderly rose in case of female, lower education, inconvenience or limitation, pain or discomfort in locomotion and daily activities, higher recognition of stress, lower interest in work, feeling of depression, despair, and weariness, restriction in activity caused by bone fracture and joint injury, having diabetes and hip-joint pain, smoking, low frequency in having breakfast and high-level physical activities. Based on this study, we envision that an effective solution for injury risk factors caused by the organic relation can be reached in the near future.

• Journal of the Korean Society for information Management
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• v.33 no.3
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• pp.371-398
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• 2016

The purpose of this study is to analyze the effect of reading activity of employees in public libraries on their job satisfaction and organizational commitment which was suggested by previous studies proving the relationship among the variables in the business area. The results from the survey indicate that there were significant differences in job satisfaction, satisfaction with human relationship, satisfaction of self-realization, affective commitment, and continuance commitment in terms of the frequency of participation in a book club. Additionally, the number of employees' reading books and hours spent for reading significantly influenced their job satisfaction and the hours spent for reading significantly influenced affective commitment. It was also found that participation continuity for a book club influenced on satisfaction level of social recognition, continuance commitment, and normative commitment. Job satisfaction level had a complete mediation effect between reading hours and affective commitment, and satisfaction from social recognition had a complete mediation effect between participation continuity in a reading meeting, continuance commitment, and normative commitment. Based on these results, this study suggests a plan for constructing a good environment for employees to read through introducing a reading management as follows. Firstly, managers of public libraries need to take an active interest in reading management and various programs to encourage employees to read need to be provided. Secondly, public libraries are required to encourage their employees' participation in book clubs and support them, so that the employees are able to participate in the book club consistently. Finally, institution-level consistent motivation is needed for an active reading activity.

• Science of Emotion and Sensibility
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• v.14 no.4
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• pp.503-512
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• 2011

Recently in HCI research, emotion recognition is one of the core processes to implement emotional intelligence. There are many studies using bio signals in order to recognize human emotions, but it has been done merely for the basic emotions and very few exists for the other emotions. The purpose of present study is to confirm the difference of autonomic nervous system (ANS) response in three emotions (boredom, pain, and surprise). There were totally 217 of participants (male 96, female 121), we presented audio-visual stimulus to induce boredom and surprise, and pressure by using the sphygmomanometer for pain. During presented emotional stimuli, we measured electrodermal activity (EDA), skin temperature (SKT), electrocardiac activity (ECG) and photoplethysmography (PPG), besides; we required them to classify their present emotion and its intensity according to the emotion assessment scale. As the results of emotional stimulus evaluation, emotional stimulus which we used was shown to mean 92.5% of relevance and 5.43 of efficiency; this inferred that each emotional stimulus caused its own emotion quite effectively. When we analyzed the results of the ANS response which had been measured, we ascertained the significant difference between the baseline and emotional state on skin conductance response, SKT, heart rate, low frequency and blood volume pulse amplitude. In addition, the ANS response caused by each emotion had significant differences among the emotions. These results can probably be able to use to extend the emotion theory and develop the algorithm in recognition of three kinds of emotions (boredom, surprise, and pain) by response measurement indicators and be used to make applications for differentiating various human emotions in computer system.

• BMB Reports
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• v.34 no.1
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• pp.73-79
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• 2001

Transcriptional activation domains are known to be inherently "unstructured" with no tertiary structure. A recent NMR study, however, has shown that the transactivation domain in human p53 is populated with an amphipathic helix and two nascent turns. This suggests that the presence of such local secondary structures within the overall "unstructured" structural framework is a general feature of acidic transactivation domains. These pre-existing local structures in p53, formed selectively by positional conserved hydrophobic residues that are known to be critical for transcriptional activity, thus appear to constitute the specific structural motifs that regulate recognition of the p53 transactivation domain by target proteins. Here, we report the results of a NMR structural comparison between the native human p53 transactivation domain and an inactive mutant (22L,23W$\rightarrow$22R,23S). Results show that the mutant has an identical overall structural topology as the native protein, to the extent that the amphipathic helix formed by the residues 18T 26L within the native p53 transactivating domain is preserved in the double mutant. Therefore, the lack of transcriptional activity in the double mutant should be ascribed to the disruption of the essential hydrophobic contacts between the p53 transactivation domain and target proteins due to the (22L,23W$\rightarrow$22R,23S) mutation.

• Biomedical Science Letters
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• v.11 no.4
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• pp.487-492
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• 2005

The baculovirus/insect cell expression system is of great value in the study of structure-function relationships in mammalian glucose-transport proteins by site-directed mutagenesis and for the large-scale production of these proteins for mechanistic and biochemical studies. Spodoptera frugiperda Clone 21 (Sf2l) cells grow well on TC-100 medium that contains $0.1\%$ D-glucose as the major carbon source, strongly suggesting the presence of endogenous glucose transporters. However, very little is known about the properties of the endogenous sugar transporter(s) in Sf2l cells, although a saturable transport system for hexose uptake has been previously revealed in the Sf cells. In order to further examine the substrate and inhibitor recognition properties of the Sf2l cell transporter, the ability of hexoses to inhibit 2-deoxy-D-glucose (2dGlc) transport was investigated by measuring inhibition constants $(K_i)$. The $K_i's$ for reversible inhibitors were determined from plots of uptake versus inhibitor concentration. Transport was effectively inhibited by D-mannose and D-glucose. Of the hexoses tested, L-glucose had the least effect on 2dGlc transport in the Sf2l cells, indicating that the transport is stereoselective. Unlike the human HepG2 type glucose transport system, D-mannose had a somewhat greater affinity for the Sf2l cell transporter than D-glucose, implying that the hydroxyl group at the C-2 position is not necessary for strong binding. However, epimerization at the C-4 position of D-glucose (D-galactose) resulted in a dramatic decrease in affinity of the hexose for the Sf2l cell transporter. Such a lowering of affinity might be the result of the involvement of the C-4 hydroxyl in hydrogen bonding. It is therefore suggested that Sf2l cells were found to contain an endogenous sugar transport activity that in several aspects resembles the human HepG2 type glucose transporter, although the insect and human transporters do differ in their affinity for cytochalasin B.

• Journal of the Korea Convergence Society
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• v.8 no.8
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• pp.225-230
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• 2017

The Sijo provides dynamic rated therapeutic activities in our life. This study aims to search for the literary therapeutic function secreted from the Sijo that ends with a noun. As a result, the noun used at the final sentence secretes a predicative function. This kind of Sijo functions as twelve sound steps, even though it is condensed of just eleven sound steps with one sound step omitted. This functional secretion of Sijo is therapeutic predicate concerned with encoding of literary therapy. Thus it become possible to activate the therapeutic encoding in Sijo or a language by uttering only noun, instead of the predicate. That's because the noun in the last sentence of Sijo permeated in the human body and is done subject, and neuron of the body becomes a predicate, so that the Sijo's subject and the neuron's predicate are fused into a sentence. During the course the human body seems to recognize that the neuron's nucleus analyzes the information of the noun and makes a new sentence. This recognition might also be regarded as a process of encoding that has therapeutic functions secreted from the human body.

• Biomedical Science Letters
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• v.15 no.1
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• pp.55-60
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• 2009

Insect cells such as Spodoptera frugiperda Clone 9 (Sf9) cells are widely chosen as the host for heterologous expression of a mammalian sugar transport protein using the baculovirus expression system. Characterization of the expressed protein is expected to include assay of its function, including its ability to transport sugars and to bind inhibitory ligands such as cytochalasin B. It is therefore very important first to establish the transport characteristics and other properties of the endogenous sugar transport proteins of the host insect cells. However, very little is known of the transport characteristics of Sf9 cells, although their ability to grow on TC-100 medium strongly suggested the presence of endogenous glucose transport system. In order to investigate the substrate and inhibitor recognition properties of the Sf9 cell transporter, the ability of pentoses to inhibit 2-deoxy-D-glucose (2dGlc) transport was investigated by measuring inhibition constants $(K_i)$. To determine the time period over which of sugar into the Sf cells was linear, the uptake of 2dGlc 0.1mM extracellular concentration was measured over periods ranging from 30 seconds to 30 minutes. The uptake was linear for at least 2 minutes at the concentration, implying that uptake made over a 1 minute time course would reflect initial rates of the sugar uptake. The data have also revealed the existence of a saturable transport system for pentose uptake by the insect cells. The transport was inhibited by D-xylose and D-ribose, although not as effective as hexoses. However, L-xylose had a little effect on 2dGlc transport in the Sf9 cells, indicating that the transport is stereoselective. Unlike the human erythrocyte-type glucose transport system, D-ribose had a somewhat greater apparent affinity for the Sf9 cell transporter than D-xylose. It is therefore concluded that Sf9 cells contain an endogenous sugar transport activity that in some aspects resembled the human erythrocyte-type counterpart, although the Sf9 and human transport systems do differ in their affinity for cytochalasin B.