• Journal of the Institute of Convergence Signal Processing
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• v.9 no.2
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• pp.121-128
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• 2008

Accurate voice activity detection have a great impact on performance of speech applications including speech recognition, speech coding, and speech communication. In this paper, we propose methods for voice activity detection that can adapt to various car noise situations during driving. Existing voice activity detection used various method such as time energy, frequency energy, zero crossing rate, and spectral entropy that have a weak point of rapid. decline performance in noisy environments. In this paper, the approach is based on existing spectral entropy for VAD that we propose voice activity detection method using MFB(Met-frequency filter banks) spectral entropy, gradient FFT(Fast Fourier Transform) spectral entropy. and gradient MFB spectral entropy. FFT multiplied by Mel-scale is MFB and Mel-scale is non linear scale when human sound perception reflects characteristic of speech. Proposed MFB spectral entropy method clearly improve the ability to discriminate between speech and non-speech for various in noisy car environments that achieves 93.21% accuracy as a result of experiments. Compared to the spectral entropy method, the proposed voice activity detection gives an average improvement in the correct detection rate of more than 3.2%.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2006.11a
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• pp.103-115
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• 2006

$\beta$-Glucan is a glucose polymer that has linkage of $\beta$-(1,3), -(1,4) and -(1,6). As exclusively found in fungal and bacterial cell wall, not in animal, $\beta$-glucans are recognized by innate immune system. Dendritic cells (DC) or macrophages possesses pattern recognition molecule (PRM) for binding $\beta$-glucan as pathogen-associated molecular pattern (PAMP). Recently $\beta$-glucan receptor was cloned from DC and named as dectin-l which belongs to type II C-type lectin family. Human dectin-1 is consisted of 7 exons and 6 introns. The polypeptide of dectin-1 has 247 amino acids and has cytoplasmic, transmembrane, stalk and carbohydrate recognition domains. Dectin-1 could recognize variety of beta-1,3 and/or beta-1,6 glucan linkages, but not alpha-glucans. In our macrophage cell line culture system, dectin-1 mRNA was detected in RA W264.7 cells by reverse transcription-polymerase chain reaction (RT-PCR). Dectin-1 was also detected in the murine organs of spleen, thymus, lung and intestines. Treatment of RA W264.7 cells with $\beta$-glucans of Ganoderma lucidum (GLG) resulted in increased expression of IL-6 and TNF-$\alpha$ in the presence of LPS. However, GLG alone did not increase IL-6 nor TNF-$\alpha$. These results suggest that receptor dectin-1 cooperate with CD14 to activate signal transduction that is very critical in immunoresponse.

• 한국약용작물학회:학술대회논문집
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• 2006.11a
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• pp.103-115
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• 2006

[ ${\beta}-Glucan$ ] is a glucose polymer that has linkage of ${\beta}-(1,3)$, -(1,4) and -(1,6). As exclusively found in fungal and bacterial cell wall, not in animal, ${\beta}-glucans$ are recognized by innate immune system. Dendritic cells (DC) or macrophages possesses pattern recognition molecule (PRM) for binding ${\beta}-glucans$ as pathogen-associated molecular pattern (PAMP). Recently ${\beta}-glucans$ receptor was cloned from DC and named as dectin-l which belongs to type II C-type lectin family. Human dectin-l is consisted of 7 exons and 6 introns. The polypeptide of dectin-l has 247 amino acids and has cytoplasmic, transmembrane, stalk and carbohydrate recognition domains. Dectin-l could recognize variety of beta-l,3 and/or beta-l,6 glucan linkages, but not alpha-glucans. In our macrophage cell line culture system, dectin-l mRNA was detected in RA W264.7 cells by reverse transcription-polymerase chain reaction (RT-PCR). Dectin-l was also detected in the murine organs of spleen, thymus, lung and intestines. Treatment of RA W264.7 cells with ${\beta}-glucans$ of Ganoderma lucidum (GLG) resulted in increased expression of IL-6 and $TNF-{\alpha}$ in the presence of LPS. However, GLG alone did not increase IL-6 nor $TNF-{\alpha}$ These results suggest that receptor dectin-l cooperate with CD14 to activate signal transduction that is very critical in immunoresponse.

• Journal of Pharmacopuncture
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• v.14 no.2
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• pp.81-91
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• 2011

Objectives & Methods: This suggestion was attempted to be elevated the recognition of common characteristics in disease. So, we performed to analyze the correlation of common cause of disease, characteristics of human body, and medical treatment. And the results are as follows. Results: 1. The cause of disease is consist of genetic factor, aging, habit, food of not good in health, weather, environment, deficit of the physical activity, stress and so on. 2. Generally, human has common and individual weakness. Individual weakness is appeared similar to the occurrence of volcano and lapse. 3. The correlation of disease and medical treatments is possible to explain using the quotation of the law of motion made by Isaac Newton, the great physicist. 4. When the process of the medical treatment was not progressed, the prognosis is determined by the correlation of the homeostasis(H') in human body and the homeostasis(H) of disease. 5. The prognosis of disease is determined by the relationship between the energy of disease(F) and medical treatment(F'). 6. The exact diagnosis is possible to predict the treatment sequence, and the facts that homeostasis in human body and disease, relationship between the energy of disease(F) and medical treatment(F'), action and reaction are important to determine the prognosis. 7. The careful observation of improving response and worsening action of disease becomes available for exact prognosis. Conclusion: The above described contents may be useful in clinical studies, and the concrete clinical reports about this will be made afterward.

• Korea Journal of Hospital Management
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• v.28 no.2
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• pp.1-8
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• 2023

Purpose: This study was conducted to identify the impact of human rights sensitivity and patient rights awareness of first-year students in clinical practice on clinical practice adaptation and to prepare practical and systematic personality development program education alternatives to foster high-quality medical personnel. Method: As for the research method, an online survey of 155 medical and nursing students from two universities in G-do (76 medical students and 79 nursing students) was conducted, and the collected data were T-test, ANOVA, Scheffe test, Pearson's correlation coefficient and step-by-step multiple regression analysis using SPSS WIN/25.0. Findings: The results of the study are as follows. First, as a result of analyzing the differences in each variable according to general characteristics, human rights sensitivity had a significant impact on gender, patient rights recognition on personality type, and clinical practice adaptation had a significant impact on major selection motivation. Second, the factors affecting the adaptation of first-year college students to clinical practice had a significant impact on extroverted personality and patient rights perception among personality types (regression model results F=6.38 (p<).001), 24.2% explanatory power). Conclusion: This study suggests that education and policy efforts are needed to foster accurate awareness of human rights issues by developing flexible and flexible extracurricular activity programs in the operation of the curriculum to strengthen medical and nursing students' ability to adapt to clinical practice and improve awareness of human rights issues.

• The KIPS Transactions:PartD
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• v.18D no.2
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• pp.143-148
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• 2011

In this paper developed a wearable activity device and algorithm which can be converted into the real-time activity and monitoring by acquiring sensor row data to be occurred when a person is walking by using a tri-axial accelerometer. Test was proceeded at various step speeds such as slow walking, walking, fast walking, slow running, running and fast running, etc. for 36 minutes in accordance with the test protocol after wearing a metabolic test system(K4B2), Actical and the device developed in this study at the treadmill with 59 participants of subjects as its target. To measure the activity of human body, a regression equation estimating the Energy Expenditure(EE) was drawn by using data output from the accelerometer and information on subjects. As a result of experiment, the recognition rate of algorithm being proposed was shown the activity conversion algorithm was enhanced by 1.61% better than the performance of Actical.

• Korean Institute of Interior Design Journal
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• v.22 no.6
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• pp.190-198
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• 2013

With globalization and the execution of a self-governing system, the government-oriented system has been transformed into a city-oriented system. The importance of the competitive power of a city is thus increasing. Because of this each region is trying to develop its own differentiated image and to create branding using unique historical and cultural resources and, as one of the strategies for this, public spaces have been developed. For a public space to be used as a means to promote the attractiveness of a city, creates a local image and works as a medium to help a community of people realize a pleasant life. Therefore, in this study, I am clarified theoretically the meaning of placeness and form factors. and study realization methods in the space around the public space case. The results of the study are as following. In the modern space, Place is to be understood as a recognition and experience. Therefore rather than spatial structure physical fixed, recognition through the human experience is an important feature of the place-making, it is necessary to access in spatial planning based on this point of view. The factors of the placeness formation are physical environment factors, activity elements of the human, the meaning factors. and these elements form the placeness through via interaction. Therefore, even space implementation of the place, it is necessary to grasp the elements of each, as well as the physical aspects in particular, planning programmatic and various functions must be parallel strategically. There is a need to implement a space device that can be carried out in space activities.

• Nutrition Research and Practice
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• v.8 no.4
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• pp.377-385
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• 2014

BACKGROUND/OBJECTIVES: Abundant consumption of seaweeds in the diet is epidemiologically linked to the reduction in risk of developing cancer. In larger cases, however, identification of particular seaweeds that are accountable for these effects is still lacking, hindering the recognition of competent dietary-based chemo preventive approaches. The aim of this research was to establish the antiproliferative potency and angiosuppressive mode of action of Stoechospermum marginatum seaweed methanolic extract using various experimental models. MATERIALS/METHODS: Among the 15 seaweeds screened for antiproliferative activity against Ehrlich ascites tumor (EAT) cell line, Stoechospermum marginatum extract (SME) was found to be the most promising. Therefore, it was further investigated for its anti-proliferative activity in-vitro against choriocarcinoma (BeWo) and non-transformed Human embryonic kidney (HEK 293) cells, and for its anti-migratory/tube formation activity against HUVEC cells in-vitro. Subsequently, the angiosuppressive activity of S. marginatum was established by inhibition of angiogenesis in in-vivo (peritoneal angiogenesis and chorioallantoic membrane assay) and ex-vivo (rat cornea assay) models. RESULTS: Most brown seaweed extracts inhibited the proliferation of EAT cells, while green and red seaweed extracts were much less effective. According to the results, SME selectively inhibited proliferation of BeWo cells in-vitro in a dose-dependent manner, but had a lesser effect on HEK 293 cells. SME also suppressed the migration and tube formation of HUVEC cells in-vitro. In addition, SME was able to suppress VEGF-induced angiogenesis in the chorio allantoic membrane, rat cornea, and tumor induced angiogenesis in the peritoneum of EAT bearing mice. A decrease in the microvessel density count and CD31 antigen staining of treated mice peritoneum provided further evidence of its angiosuppressive activity. CONCLUSIONS: Altogether, the data underline that VEGF mediated angiogenesis is the target for the angiosuppressive action of SME and could potentially be useful in cancer prevention or treatment involving stimulated angiogenesis.

• Journal of the Korean housing association
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• v.27 no.5
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• pp.73-81
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• 2016

Focused on developing form of Western architecture, invisible elements covering actual human life has been dealt with separately and the time was turned away and disparaged. But now the phenomenology, arranging such a meeting of space and time, gives opportunity to look at the actual life in architecture. Recently, Guille Deleuze and Merleau-Ponty tried to recover the sense of touch segregated in skin from body keeping eyes for distance. And the activity can be happened by being connected to the body rather than to eye in the space. From the phase of recognition where the human body tries to identify the object in the space considering a time, it will be changed for the subject to the phase of space-time structure. If the tactility is to erase the distance different from the visuality in dichotomy, it will be occurred to having a tension and makes new relationship to work trying to move the subjective point of view in object. Like this evidence in analysis of architecture, it can be found these in the Korean traditional architecture rather than Western architecture in terms of emphasizing the time and space. And this study will be intensive to the side of the Phenomenology how it is being connected to the movement in the space and time for the subject and object.

• Korean Institute of Interior Design Journal
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• v.19 no.6
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• pp.197-205
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• 2010

For the spatial experience of spectators visiting a museum, the route search of trying to follow the spatial structure or production of exhibition and the information search of trying to see are accomplished at the same time. In such process, the spectator's reaction of visual perception produces the result of emotional reaction and action exchanged between human and space by going through the recognition and perception on the target of environment factor. For the spatial experience of a spectator, the reaction of visual perception which interacts according to the exhibit and exhibition environment within space according to viewing purpose, interest and concern of spectator comes out as visual activity which is an activity to understand the spatial information shown as various activities according to spatial structure and unfolding characteristics of the display. The purpose of this study is to identify The Correlation of Spectator Movement Created According to Structural Form of Exhibition Area Based on Interaction between Exhibition Area Structure and Spectator to utilize as basic material while designing museum exhibition using isovist field which is a quantitative analysis tool of spectator's visual behavior and spatial structure at each exhibition area.