• Title/Summary/Keyword: Human values

Search Result 3,222, Processing Time 0.03 seconds

In vitro Metabolism of Pentoxifylline Metabolite M-l in Human Liver Microsomes (인체 간 microsome에서 pentoxifylline 대사체 M-1의 시험관내 대사)

  • 신혜순
    • YAKHAK HOEJI
    • /
    • v.43 no.6
    • /
    • pp.834-842
    • /
    • 1999
  • The metabolism and pharmacokinetics of M-l, which is metabolite of pentoxifylline, have been studied in human liver microsomes. Biphasic kinetics was observed from the Eadie-Hofstee plot for the formation of both metabolites of M-l. For the kinetics of pentoxifylline, mean values of $V_{max1}{\;}and{\;}V_{max2}$ were 1,648 and 5,622 nmol/min/mg protein, and the estimated values of $K_{ml}{\;}and{\;}K_{m2}$ were 0.180 and 4.829 mM, respectively. For M-3, mean values of $V_{max1}{\;}and{\;}V_{max2}$ were 0.062 and 0.491 nmol/min/mg protein, and estimated values of $K_{ml}{\;}and{\;}K_{m2}$ were 0.025 and 1.216 mM. The formations of pentoxifylline and M-3 from M-1 were indentified by using several selective inhibitors of cytochrome P450 isoformes at 0.05-5 mM concentration of M-1 in human liver microsomes. For the analysis of low (0.05 mM) concentration of M-1, where the affinity was expected as low, indicated that CYPlA2 and CYP3A4 were major P450 isoforms responsible for pentoxifylline and M-3 formation. CYP3A4 and CYP2A6 appeared to be P450 isoforms responsible for M-3 formation at high (5 mM) concentration of M-1.

  • PDF

Investigation of Retail Therapy (RT) Values -How Body Consciousness Plays a Role in Therapeutic Shopping Motivations-

  • Lee, Sea Eun;Yoo, Jeong-Ju
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.45 no.4
    • /
    • pp.714-726
    • /
    • 2021
  • The purpose of this study is to investigate the effect of retail therapy (RT) values and the role of body consciousness on therapeutic shopping motivations and outcomes. In order to accomplish our research aim, we investigated therapeutic shopping values (i.e., positive mood reinforcement and negative mood reduction) and the moderating effects of body surveillance, body shame, and weight preoccupation. A total of 247 female college students in the United States participated in an online Qualtrics survey, and structural equation modeling (SEM) and multigroup analysis were performed to analyze the data. The findings reveal that therapeutic shopping values (positive mood reinforcement and negative mood reduction) significantly influence therapeutic shopping motivation. Therapeutic shopping motivation, in turn, positively influences therapeutic shopping outcomes. Moreover, weight preoccupation moderates the relationship between negative mood reduction and therapeutic shopping motivation, suggesting that RT should especially be utilized for weight-conscious individuals. The results can be utilized for retailers to develop marketing strategies for consumers who are conscious about their appearance. Academic and managerial implications, along with future research, are suggested.

A Study on the Ethical Values of Clinical Nurses (임상 간호사의 윤리적 가치관에 관한 연구)

  • Park, Myung-Hee;Kim, Chang-Sook
    • The Journal of Korean Academic Society of Nursing Education
    • /
    • v.9 no.1
    • /
    • pp.30-40
    • /
    • 2003
  • This study was conducted to identify the ethical values of clinical nurses. 119 nurses working in clinical setting were selected Gwangju city and Chunnam area. Data were gathered from April. 1 to June. 27, 2001 by structured questionares. Analysis of data was done by SPSS using percentage, t-test, one-way ANOVA, pearson's correlation. The results obtained from data were as follows : 1. The ethical values of human life area slightly took up the position of utilitarian. In human life area mean score was 2.41. This area showed remarkerble individual differences between utilitarian and deontological position. 2. The ethical values of clients area took up the position of utilitarian position. In clients area mean score was 1.75. 3. The ethical values of nursing practice area took up deontological position. In nursing practice area mean score was 2.58. 4. The ethical values of nurses-co-worker area took up deontological position. In nurses- co-worker area mean score was 2.94. 5. Those who have younger, higher education level, less job experience, singles, religion, lower position, positive attitude of nursing and firm ethical standard took up more deontological position than those who have not. 6. There were significant relationship between human life area & client area(r=.566 p=.000), nursing practice area(r=.698 p=.000). There were significant relationship between client area & nursing practice area(r=.342 p=.001). There were significant relationship between nursing practice area & nurses-co-worker area(r=.491 p=.001).

  • PDF

The Aesthetic Values of the Korean Traditional Costume (한국 복식의 미적 가치에 대한 고찰 -조선 복식을 중심으로-)

  • 김윤희
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.21 no.5
    • /
    • pp.946-955
    • /
    • 1997
  • The purpose of this study is to present the aesthetic values of the Korean traditional costume for developing 'Korean' fashion design can be accepted in general in the modern times. For this purpose, documentary studies about the aesthetic values of the Korean traditional art and Korean traditional costume were preceded. And the perception of the Korean traditional costume were studied according to Belong's two criteria, body priority/ clothes priority and open/closed. Next, the aesthetic values of the Korean traditional costume were re-defined. The results can be summarized as follows; 1) The aesthetic values of the Korean traditional art are the beauty of nature, the purity, and the pleasantry. As the beauty of nature is the important one, the purity is caused by the love of nature. The pleasantry is as a way of expression. 2) The aesthetic values of the Korean traditional costume through the documentary studies stand for as the beauty of nature, the purity, the beauty of evil's eye, the beauty of symbolism, the beauty of personality, the beauty of tragedy and the beauty of tradition. 3) Korean traditional costume are perceived as clothes priority and open. 4) The aesthetic values of the Korean traditional costume can be re-defined as the beauty of nature, the purity, and the pleasantry. The beauty of nature comes from the 'natural' look, the exposure of the fabric as itself and the organic lines of the Korean traditional costume. The purity comes from the geometrical squared clothing form of Korean traditional costume which doesn't revive the human body form. The Pleasantry is seen the colors and motifs of costumes that have the human's hope and incantation and the exaggeration and distortion of human body form.

  • PDF

Comparative Study of Coupling Factors for Assessment of Low-Frequency Magnetic Field Exposure

  • Shim, Jae-Hoon;Choi, Min-Soo;Jung, Kyu-Jin;Kwon, Jong-Hwa;Byun, Jin-Kyu
    • Journal of Magnetics
    • /
    • v.21 no.4
    • /
    • pp.516-523
    • /
    • 2016
  • In this paper, coupling factors are calculated based on numerical analysis in order to assess various non-uniform low-frequency magnetic field exposure situations. Two types of non-uniform magnetic field sources are considered; circular coil and parallel wires with balanced currents. For each magnetic field source, source current values are determined so that reference magnetic field magnitude can be measured at the specified point on the human model. Various exposure situations are investigated by changing parameters such as the distance between source and human model, radius of circular coil, and the gap between parallel wires. For equivalent human models, prolate spheroid model and simplified human model from IEC 62311 standard are used. The calculated coupling factor values are compared with those obtained by 2D uniform disk human model, and the dependence of coupling factor on the choice of equivalent human model is analyzed.

The Physicochemical and Sensory Characteristics of Jook Containing Different Levels of Skate(Raja kenojei) Flour (홍어 분말을 첨가한 죽의 품질 특성)

  • Kim, Kyung-Hee;Cho, Hee-Sook
    • Journal of the East Asian Society of Dietary Life
    • /
    • v.18 no.2
    • /
    • pp.207-213
    • /
    • 2008
  • This study examined the effects of added amounts of skate (Raja kenojei) flour on the physical and sensory properties, and consumer acceptability of Jook. As the level of skate flour increased the L-values and b-values decreased, and a-values increased. The Jook also had higher viscosity and lower spread ability values as the amount of skate flour increased. Sensory characteristics, such as color intensity, viscosity, nutty taste, and off-flavor increased significantly with the addition of skate flour. A consumer acceptability test indicated that the 3% skate flour group had the highest overall acceptability, appearance, flavor, and texture. In conclusion, to enhance the quality of Jook, a 3% addition of skate flour would be the useful.

  • PDF

Evaluation of the Ride Values of Passenger Cars on the Unevenness and Endurance Roads (내구력 도로와 요철 도로에서 승용차의 승차감 지수 평가)

  • 조영건;정완섭;박세진;윤용산
    • Journal of KSNVE
    • /
    • v.7 no.6
    • /
    • pp.1025-1030
    • /
    • 1997
  • This paper introduces the experimental results of ride values assessed for several passenger cars. The experiment was conducted at four vehicles on two roads for three persons by measuring the acceleration in the 12-axis of human. The results include the comparison of the ride values, such as the component ride values, overall ride value, and seat effective amplitude transmissibiity. It is proved that acceleration between 1 and 15Hz is the most significant in evaluating the ride quality. The contribution of the acceleration in each measurement axis is quantified from the component ride value. SEAT value shows a relatively low sensitivity for the road condition and human mass.

  • PDF

Quality Characteristics of Jook Prepared with Lotus Leaf Powder (연잎 분말을 첨가한 죽의 품질 특성)

  • Park, Bock-Hee;Cho, Hee-Sook;Jeon, Eun-Raye;Kim, Sung-Doo
    • Korean journal of food and cookery science
    • /
    • v.25 no.1
    • /
    • pp.55-61
    • /
    • 2009
  • This study examined the effects of added amounts of lotus leaf powder on the physical and sensory properties of Jook. As the level of lotus leaf powder in samples increased, L-values and a-values decreased and b-values increased. In addition, the Jook had higher viscosity and lower spreadability values as the amount of lotus leaf powder increased. Sensory characteristics such as color intensity, viscosity, astringency, and nutty taste increased significantly with the addition of lotus leaf powder. And the results of the consumer acceptability test showed that the Jook containing $2%{\sim}3%$ lotus leaf powder had the highest score. In conclusion, to enhance the quality of Jook, a 2% addition of lotus leaf powder would be the most beneficial.

Choline intake and its dietary reference values in Korea and other countries: a review

  • Shim, Eugene;Park, Eunju
    • Nutrition Research and Practice
    • /
    • v.16 no.sup1
    • /
    • pp.126-133
    • /
    • 2022
  • Choline is a water-soluble organic compound that is important for the normal functioning of the body. It is an essential dietary component as de novo synthesis by the human body is insufficient. Since the United States set the Adequate Intakes (AIs) for total choline as dietary reference values in 1998, Australia, China, and the European Union have also established the choline AIs. Although choline is clearly essential to life, the 2020 Dietary Reference Intakes for Koreans (KDRIs) has not established the values because very few studies have been done on choline intake in Koreans. Since choline intake levels differ by race and country, human studies on Koreans are essential to set KDRIs. Therefore, the present study was undertaken to provide basic data for developing choline KDRIs in the future by analyzing data on choline intake in Koreans to date and reference values of choline intake and dietary choline intake status by country and race.

Assessment of Quality Characteristics of the Shrimp Powder, Jook, for Elderly Foodservice Operation (노인급식에 적용하기 위한 새우 죽의 물리적, 관능적 품질특성 평가)

  • Cho, Hee-Sook;Kim, Kyung-Hee
    • Journal of the Korean Society of Food Culture
    • /
    • v.24 no.4
    • /
    • pp.419-425
    • /
    • 2009
  • This study examined the effects of added amounts of shrimp powder on the physical and sensory properties of Jook for elderly foodservice operation. According to the amylograph data, the composite shrimp flour-wheat flour samples increased the gelatinization temperature, with increasing shrimp-flour content; moreover, initial viscosity at $95^{\circ}C$, viscosity at $95^{\circ}C$ after 15 minutes, and maximum viscosity were reduced. As the level of shrimp powder in samples increased, L-values decreased, and a-values and b-values increased. In addition, the Jook had higher viscosity and lower spreadability values as the amount of shrimp powder increased. Sensory characteristics, such as nutty taste, color, viscosity, and overall preference increased significantly with the addition of shrimp powder. In conclusion, to enhance the quality of Jook, a 3% addition of shrimp powder would be the most beneficial.