• Toxicological Research
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• v.11 no.1
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• pp.77-80
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• 1995

Antigenic potential of genetically-engineered human erythropoietin (EPO) was assessed in guinea pigs (active systemic anaphylaxis [ASA] ; passive cutaneous anaphylaxis [PCA]) and in vitro (hemagglutination test [PHA]). In ASA, EPO at 70~700 U/kg elicited a weak anaphylactic response tvhereas the positive control ovalbumin (OVA) did cause intensive responses leading to death in 40% animals. However, the extract of CHO cells, to which EPO gene was introduced, did not cause any symptom. In PCA and PHA tests, neither EPO nor CHO cell extract induced positive responses. OVA, in contrast, produced high titers in both PCA and PHA tests. It was concluded that, in light of the fact that EPO was slightly antigenic only in ASA but not in PCA or PHA and also that human EPO is a foreign protein to guinea pigs, the present EPO may not be antigenic in humans.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.13 no.3
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• pp.186-193
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• 2003

Floor vibrations in residence and office buildings are typically induced by heel drop and walking movement of occupants. The criteria of most vibration provisions have been developed based on the vibration caused by heel drop impact rather than walking. There may be considerable differences between the vibration characteristics induced by walking and heel drop. The effect of walking vibration was not well reflected on current provisions. In this paper, shaking table test was performed to investigate the human perception level against the vibrations due to walking and heel drop. This study attempts to compare the human Perception level of two different vibration sources. Also, this study investigates the effect of damping on a Perception level under heel drop and walking vibration.

• Biomolecules & Therapeutics
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• v.3 no.1
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• pp.63-71
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• 1995

The local irritation studies of DA-3002, an authentic recombinant human growth hormone (rhGH), were carried out in rabbits after the following treatment ; application into the conjunctival sac of the eye (single), single subcutaneous and intramuscular injection, 7-day repeated subcutaneous and intramuscular injection. The results obtained were as follows. In the result of ocular irritation test, 0.16% solution of DA-3002 could be considered as a non-irritating material. In single subcutaneous and intramuscular irritation test, the irritancy of 0.16% DA-3002 solution was not so much different from that of saline. The local irritation of DA-3002 by 7-day repeated injection was negligible and similar to that of saline by both subcutaneous and intramuscular routes. These results suggest that DA-3002 has no irritating activity when injected through subcutaneous or intramuscular route for clinical practice as 0.16% solution.

• Korean Journal of Human Ecology
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• v.16 no.3
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• pp.563-576
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• 2007

The purpose of this study is to analyze the financial performance according to the economic environment change. The data of 4,577 households in 2003 and 3994 households in 2000 is from the Korean Labor and Income Panel Study. The data were analyzed by various statistical methods such as frequency, mean-test, Duncan's multiple range test, k-mean cluster analysis. Findings were as follows; First, the classified household financial strategy types were Residual(44.3%), Financial Assets(24.0%), Informal Institutional(19.7%), Diversified Portfolio(7.6%), Real Estate(4.5%). Second, the criteria of classification of the financial strategies were relative, not absolute. Third, the rate of economic growth was high and the index of the current money was low in 2000. Fourth, households that employed a diversified portfolio strategy had the greatest net wealth.

• Korean Journal of Human Ecology
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• v.17 no.4
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• pp.679-692
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• 2008

The goal of this study is to analyze one-child households' financial structure. The data from 1022 more than two children households and 236 one-child households were taken from the Korean Labor and Income Panel Study(2004). This study compared demographic, socioeconomic and marital characteristics between one-child households and more than two children households. A chi-square test, t-test and multiple regression analysis were used. The major findings were as follows: One-child households were different from more than two children households in demographic socioeconomic characteristics and financial structure. In one-child households, the variable that significantly influenced on consumption expenditures was monthly income and the variables that significantly influenced on private education expenditures were householder's age, home-ownership, monthly income.

• KIEAE Journal
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• v.3 no.2
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• pp.59-66
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• 2003

To be the design method supporting aesthetic ability of human, CAAD system should essentially recognize architectural form in the same way of human. In this study, visual perception process of human was analyzed to search proper computational method performing similar step of perception of it. Through the analysis of visual perception, vision was separated to low-level vision and high-level vision. Edge detection and neural network were selected to model after low-level vision and high-level vision. The 24 images of building, tree and landscape were processed by edge detection and trained by neural network. And 24 new images were used to test trained network. The test shows that trained network gives right perception result toward each images with low error rate. This study is on the meaning of artificial intelligence in design process rather than on the design automation strategy through artificial intelligence.

• Proceedings of the IEEK Conference
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• 2008.06a
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• pp.911-912
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• 2008

In the present paper, a new framework, which is called visual SSIM (VSSIM), is proposed by incorporating crucial human factors into the SSIM. The human factors are foveation, luminance, frequency and motion information. Subjective quality test compliant with the Video Quality Expert Group (VQEG) multimedia group test plan shows that the visual SSIM is more correlated with the subjective quality result than the conventional SSIM.

• Proceedings of the Korean Nuclear Society Conference
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• 1995.10a
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• pp.117-122
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• 1995

An Integrated Test Facility(ITF) is a human factors experimental environment to evaluate an advanced man machine interface(MMI) design. The ITF includes a human machine simulator(HMS) comprised of a nuclear power plant function simulator, man-machine interface, experiment control station for the experiment control and design, human behavioural data measurement system, and data analysis and experiment evaluation supporting system(DAEXESS). The most important features of ITF is to secure the flexibility and expandibility of Man Machine Interlace(MMI) design to change easily the environment of experiments to accomplish the experiment's objects In this paper, we describe a development scope and characteristics of the ITF such as, hardware and software development scope and characteristics, system thermohydraulic modelling characteristics, and experiment station characteristics for the experiment variables design and control, to be used as an experiment environment for the evaluation of VDU-based control room.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.2010-2012
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• 2008

This study describes a system for human sensibility evaluation using PPG(photoplethysmogram) signal and biofeedback algorithm to respond the bad(negative) mood. For this objective, PPG signals for two emotional states(positive/negative) are collected. To evoke the test emotions, happy(or joyful) and sad(or irritating) movie files are collected and played in subjects' monitor. From the acquired PPG signal, the heart rate variability(HRV) is calculated. Using the HRV and its FFT spectra, the human sensibility is evaluated. Since the heart is a representative organ which is controlled by the autonomic nervous system(ANS), the ANS may reflect the changes in emotion. The biofeedback algorithm is designed with motion image player interacting with the results of the sensibility evaluation. It was shown that HRV was changed according to the subject's emotions. Accordingly, the sensibility evaluation test showed feasibility of the our method.

• Korean Journal of Human Ecology
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• v.2 no.1
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• pp.52-67
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• 1999

The primary purpose of this study was to analyze the types of home managers in association with effects of resourcefulness, communication and the conditions for effective home management＇ proposed by Shape and Winter(1991). A survey was conducted by subjects of 300 wives in Kwangju city. The statistical data were obtained by cluster analysis, one-way ANOVA, Duncan＇s test and chi-square test. Manager types based on the four conditions, resourcefulness and communication were classified into four clusters. Educational background, job status, family types, family life cycle and age difference between the oldest and the youngest child of the subjects were different from manager types. In conclusion, this study identified the four conditions of performance-condition dichotomy, timing, high level and middle range, resourcefulness, and communications in order to develop managerial capability. (Korean J Human Ecology 2(1) : 52∼67, 1999)