• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2005년도 생물공학의 동향(XVII)
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• pp.953-953
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• 2005

• 한국생태학회:학술대회논문집
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• 한국생태학회 1998년도 춘계공동 학술발표대회
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• pp.96-96
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• 1998

• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2001년도 제2회 생물정보학 국제심포지엄
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• pp.37-47
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• 2001

No Abstract, See Full-text

• BMB Reports
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• 제43권5호
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• pp.362-368
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• 2010

Dermcidin is a human antibiotic peptide that is secreted by the sweat glands and has no homology to other known antimicrobial peptides. As an initial step toward understanding dermcidin's mode of action at bacterial membranes, we used homonuclear and heteronuclear NMR to determine the conformation of the peptide in 50% trifluoroethanol solution. We found that dermcidin adopts a flexible amphipathic $\alpha$-helical structure with a helix-hinge-helix motif, which is a common molecular fold among antimicrobial peptides. Spin-down assays of dermcidin and several related peptides revealed that the affinity with which dermcidin binds to bacterial-mimetic membranes is primarily dependent on its amphipathic $\alpha$-helical structure and its length (>30 residues); its negative net charge and acidic pI have little effect on binding. These findings suggest that the mode of action of dermcidin is similar to that of other membrane-targeting antimicrobial peptides, though the details of its antimicrobial action remain to be determined.

• 한국콘텐츠학회논문지
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• 제17권10호
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• pp.463-471
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• 2017

이야기콘텐츠 창작 시 작동하는 무의식의 세계가 있다. 작가도 모르는 심연의 무의식 층은 전 인류가 연결되어있기 때문에 작가자신도 모르게 공통의 이야기를 만드는 길로 간다. 이렇게 만들어진 이야기가 원형신화고 오늘날 중요저작도구로 사용되고 있다. 이 원형신화가 발견되기 전에 제작된 무성영화 '달세계 여행'의 구조를 분석하면 여전히 원형의 틀을 찾을 수 있다. 이 영화는 동시대 네 작품으로부터 받은 영감을 작가가 직관적 상상으로 제작한 것임에도 원형의 틀이 완벽하게 드러났다. 이점은 신화의 원형이 지역이나 시간과 상관없이 관계하고 있는 것이다. 짧은 시간에 창작된 이야기가 오랜 시간 전승해온 신화와 같은 구조를 가지고 있는 이유는 인간의 집단 무의식속에 이야기의 원형들이 있기 때문이다. 이 원형이 이야기의 길을 결정해준다. 인간의 두뇌가 무한히 자유로운 상상을 하는 것이 아니라 이 원형의 길을 따라서 겉칠을 하며 응용을 하 는 것이다. 좋은 이야기 콘텐츠는 우리의 집단무의식속 원형이 제시하는 길을 가지 않으면 성공할 확률이 줄어든다.

• 사상체질의학회지
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• 제9권1호
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• pp.1-12
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• 1997

Neiging Medicine(內經醫學) based on Yin-Yang and Five elements was the main stream of Korea Traditional Medicine until the end of 19th century. And the establishment of Sasang Constitutional medicine. In this paper, author proved that the Yin-Yang of Sasang Constitutional Medicine was different from that of Neiging Medicine and that explained the Yin-Yang of Sasang Constitutional Medicine as our own medicine. After considering the philosophical and medical background of Sasang Constitutional Medicine, and author researched the Yin-Yang of ontology, structure, function, symptoms in Sasang Constitutional Medicine. Also we compared this with that of Neiging medicine. The results were as follows 1. Neiging Medicine was based on the Yin-Yang and Five elements centering on the nature and Sasang joy, and pleasure centering on the human. 2. The ontology of Sasang Constitutional Medicine were the mind as a unitary substance, the mind and body as a dual substance, and affair, mind, body, and objects as a four substance which were the basic theory of philosophy. 3. Sasang Constitutional Medicine explained social phenomenon with a four substancial structure consisted of affairs, mind, body, and objects, a complex four substancial structure consisted of heaves, human, nature and order, and a three dimension structure including time. 4. On the other hand Neiging Medicine recognized seven emotions as five emotions, Sasang Constitutional Medicine recognized seven emotions as qi, nature, and emotions which consisted of sorrow, anger, joy, and pleasure. The qi had an effect on internal and external part of body and the nature and the emotion had an effect on the upward and downward of body. 5. It was taked great importance to control the up and down balance and the internal and external balance in Sasang Constitutional Medicine instead of reinforcing and reducting method of Neiging Medicine. 6. The Yin-Yang of Korean Traditional Medicine developed centering on the human from centering on the nature and Sasang Constitutional Medicine was a practical medicine compared with Neiging Medicine.

• 한국전자통신학회논문지
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• 제12권4호
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• pp.539-544
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• 2017

본 논문에서는 휴먼 카운팅 시스템을 위한 광대역 패치 안테나가 공기 유전체 층을 이용하여 설계, 제작 및 측정되었다. 제안된 안테나는 5 mm의 공기 유전체 위에 정사각형 구조의 패치 구조를 가지며, CPW 전송선로 구조의 입력부와 패치면의 수직 연결은 계단형 임피던스 구조로 구현하였다. 3차원 EM 설계를 통해 최적화된 광대역 패치 안테나는 16.6 * 16.6 * 5.0 mm3의 크기로 3D 프린터를 이용하여 안테나 지그를 제작하여 지그 위에 제작되었다. 제작된 안테나는 7.2 ~ 9.8 GHz 주파수에서 2:1 이하의 VSWR과 5.71 dBi의 최대 이득을 가지며, $70^{\circ}$의 반전력 빔폭 특성을 나타내었다.

• BMB Reports
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• 제33권3호
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• pp.195-201
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• 2000

A human gene has been reported that may encode the enzyme acetohydroxyacid synthase. Previously this enzyme was thought to be absent from animals although it is present in plants and many microorganisms. In plants, this enzyme is the target of a number of commercial herbicides and the use of these compounds may need to be reassessed if the human enzyme exists and proves to be susceptible to inhibition. Here we report the construction of several plasmid vectors containing the cDNA sequence for this protein, and their expression in Escherichia coli. High levels of expression were observed, but most of the protein proved to be insoluble. The small amounts of soluble protein contained little or no acetohydroxyacid synthase activity. Attempts to refold the insoluble protein were successful insofar as the protein became soluble. However, the refolded protein did not gain any acetohydroxyacid synthase activity. In vivo complementation tests of an E. coli mutant produced no evidence that the protein is active. Incorrect folding, or the lack of another subunit, may explain the data but we favor the interpretation that this gene does not encode an acetohydroxyacid synthase.

• Restorative Dentistry and Endodontics
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• 제47권4호
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• pp.42.1-42.11
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• 2022

Objective: This study investigated the effects of various concentrations of sodium hypochlorite (NaOCl) on human whole-blood clotting kinetics, the structure of the blood clots formed, and transforming growth factor (TGF)-β1 release. Materials and Methods: Human whole blood was collected from 5 healthy volunteers and divided into 4 groups: CG (control, 0.5 mL of blood), BN_0.5 (0.5 mL of blood with 0.5 mL of 0.5% NaOCl), BN₃ (0.5 mL of blood with 0.5 mL of 3% NaOCl), and BN_5.25 (0.5 mL of blood with 0.5 mL of 5.25% NaOCl). The effects of NaOCl on clotting kinetics, structure of fibrin and cells, and release of TGF-β1 were assessed using thromboelastography (TEG), scanning electron microscopy (SEM), and enzyme-linked immunosobent assay, respectively. Statistical analysis was conducted using the Kruskal Wallis and Mann-Whitney U tests, followed by the post hoc Dunn test. A p value < 0.05 indicated statistical significance. Results: The blood samples in BN_0.5 and BN₃ did not clot, whereas the TEG of BN_5.25 showed altered clot formation. Samples from the CG and BN₃ groups could only be processed with SEM, which showed that the latter lacked fibrin formation and branching of fibers, as well as clumping of red blood cells with surface roughening and distortion. TGF-β1 release was significantly highest in BN₃ when all groups were compared to CG (p < 0.05). Conclusions: Each concentration of NaOCl affected the release of TGF-β1 from blood clots and altered the clotting mechanism of blood by affecting clotting kinetics and cell structure.

• 노동경제논집
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• 제25권3호
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• pp.35-57
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• 2002

본고는 1997년 경제위기를 전후한 고용조정의 효과를 인력구조와 임금구조 측면에서 살펴보았다. 아울러 기업 내부에서의 인적자본의 외부효과에 대한 이론적 모형을 제시하고 그것을 추정하였다. 인력구조의 변화와 임금구조의 변화를 연계하면 1997년 경제위기를 전후해서 상대적으로 노동공급의 변화보다 노동수요의 감소가 더 컸다고 할 수 있다. 교육 인적자본, 근속에 따라 축적되는 인적자본, 기혼자가 가지고 있는 인적자본, 사무직이 가지고 있는 인적자본에 대해서는 정의 외부효과로 추정되는 결과를 얻었고, 연령이 높은 근로자와 관리자의 인적자본에 대해서는 부의 외부효과로 추정되는 결과를 얻었다. 경제위기를 전후해서 각 근로자 집단의 외부효과의 증감에 따라 그 근로자 집단에 대한 고용조정의 효율성 제고 여부를 판단하면, 연령별, 근속년수별 고용조정과 관리자에 대한 고용조정은 기업의 효율성을 제고하는 방향으로 진행되었다고 할 수 있지만, 기혼 근로자와 사무직에 대한 고용조정은 그렇다고 할 수 없다.