• Title/Summary/Keyword: Human papillomavirus

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Human Papilloma Virus Attributable Head and Neck Cancer in the Sudan Assessed by p16INK4A Immunostaining

  • Ahmed, Hussain Gadelkarim;Mustafa, Saadalnour Abusail;Warille, Eyman
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.12
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    • pp.6083-6086
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    • 2012
  • Background: The aim of this study was to screen for human papillomavirus (HPV) infections in head and neck squamous cell carcinomas (HNSCCs) using P16 immunostaining. Materials and Methods: A retrospective study was performed on 150 samples from patients diagnosed with HNSCCs. HPV status was determined using $p16^{INK4A}$. Results: 31 of the 150 (20.7%) HNSCCs were HPV positive. Conclusions: A large proportion of HNSCCs in Sudan are associated with HPV infection. The fact that the prevalence of HPV is high among Sudanese patients with head and neck cancers (HNC) has obvious implications for vaccine therapy.

DETECTION OF HUMAN PAPILLOMAVIRUS DNA IN RESPIRATORY TRACT PAPILLOMA USING POLYMERASE CHAIN REACTION(PCR) (중합효소 반응을 이용한 후두유두종 Human papillomavirus DNA의 검색)

  • 김광현;성명훈;정원호;최영민;박경찬
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1991.06a
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    • pp.18-18
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    • 1991
  • 후두유두종은 호흡기계에 발생하는 양성종양중 가장 흔한 질환으로 연령에 따라 소아형과 성인형으로 분류하는데 다발성 병변이 흔하고 재발율이 높다고 알려져 있다. 후두유두종의 원인으로는 human papillomavirus의 감염으로 생각되며 잠복 감염으로 인하여 후두유두종이 재발된다고 알려져 있다. Gissman등에 의해 HPV 11이 발견되었음이 보고된 이래 최근까지 HPV 6와 11이 후두유두종의 원인이 된다고 알려져 있다. HPV의 검출에는 Southern blotting이나 in-situ hybridization 방법이 알려져 있는데 저자들은 현재까지의 바이러스 검색방법 중 가장 예민한 방법인 PCR을 이용하여 후두유두종의 HPV DNA를 조사하여 보고자 한다. 저자들은 1989년 10월부터 1900년 12월까지 서울대병원 이비인후과에서 수술을 시행받은 후두유두종 환자 15예를 대상으로 하였으며 이중 소아형은 9예이었고 성인형은 6예였으며 대부분 다발성 병변이었다. HPV 6는 15예중 10예에서 HPV 11은 15예중 6예에서 발견되었으며 두가지 형이 같이 발견된 경우는 1예가 있었다. 소아형의 경우에는 HPV 6와 11이 각각 5예로 비슷한 비율로 검출된 반면 성인형에서는 HPV 6가 주로 검출되었다.

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Factors Influencing mothers' intention to vaccinate their elementary school sons against human papillomavirus (초등학교 고학년 남학생 어머니의 자녀 인유두종 바이러스 백신 접종의도 영향요인)

  • Park, Eun-Young;Kim, Tae-Im
    • Women's Health Nursing
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    • v.26 no.1
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    • pp.37-48
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    • 2020
  • Purpose: The purpose of this study was to identify the factors influencing mothers' intention to vaccinate their elementary-school sons against human papillomavirus (HPV). Methods: The participants were 151 mothers of fourth- to sixth-grade boys at three elementary schools in Daejeon, Korea. The data were analyzed using SPSS for Windows version 25.0. Descriptive statistics, the independent t-test, one-way analysis of variance, the Mann-Whitney U test, Pearson correlation coefficients, and multiple regression analysis were used. Results: The mothers' score for intention to vaccinate their sons against HPV was 5.04 out of 7. Self-efficacy (β=.60, p<.001) and subjective norms towards HPV vaccination (β=.30, p<.001) were significant factors influencing mothers' intention to vaccinate their elementary-school sons against HPV. These factors accounted for 81.0% of HPV vaccination intention among mothers (F=160.84, p<.001). Conclusion: The results of this study suggest that to increase the HPV vaccination rate for elementary-school boys, it is necessary to develop intervention strategies to improve mothers' self-efficacy and subjective norms towards HPV vaccination and to verify the effects of those strategies. This research provides a foundation for designing interventions to increase the HPV vaccination rate of elementary-school boys.

Knowledge about Cervical Cancer, Health Beliefs and Human Papillomavirus Vaccination Rate in Female University Students (여대생의 자궁경부암 지식, 인유두종바이러스 예방접종 관련 건강신념 및 접종실태)

  • Lee, Eun-Joo;Park, Jeong-Sook
    • Asian Oncology Nursing
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    • v.11 no.1
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    • pp.65-73
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    • 2011
  • Purpose: This study was a descriptive study to determine knowledge regarding cervical cancer, health beliefs, and Human Papillomavirus (HPV) vaccination rate of female university students. Methods: The subjects of this study were 777 female university students. The data were collected through interviews using a structured questionnaire from september 1 to October 30, 2010. The data were analysed using descriptive statistics, t-test, ANOVA, and chi-square test. Results: The mean of cervical cancer knowledge was low (13.75 score). Regarding health beliefs about HPV vaccination, the levels of perceived benefit (3.01 score) and seriousness (2.91 score) were relatively high, whereas the levels of perceived barrier (2.09 score) and susceptibility (2.01 score) were relatively low. The rate of HPV vaccination was 5.5%. Conclusion: These results show that concrete educational programs and advertisement are mandated to reduce HPV infection and increase HPV vaccination rate. Also the strategies emphasizing perceived seriousness and benefits of obtaining HPV vaccination are taken into account in developing educational programs in addition to knowledge improvement on HPV and cervical cancer.

The Relationships among Knowledge, Information Seeking Behavior, and Willingness for Education about Human Papillomavirus Vaccination in the Middle or High School Teachers (중·고등학교 보건교사의 자궁경부암 예방백신에 대한 지식과 암 정보추구행위 및 교육의지)

  • Kim, Chang Hee;Song, Ju-Eun
    • Journal of Korean Biological Nursing Science
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    • v.14 no.4
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    • pp.239-248
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    • 2012
  • Purpose: The purpose of this study was to identify the relationships among knowledge, cancer information seeking behavior, and Willingness for education about Human Papillomavirus (HPV) vaccination among school teachers. Methods: The subjects were 135 teachers who had were working in the middle or high school in Korea. Data were collected by a self-report questionnaire, 2011. Data were analyzed by using the SPSS WIN 18.0 program. Results: There was a positive relationship between information seeking behavior and Willingness for education about HPV vaccination. There were differences in Willingness for education according to necessity of HPV vaccination for premarital women above 16-year old and marital women below 45-year old, and necessity of education for students. The Willingness for education were predicted by information seeking behavior, groups who HPV vaccination is necessary to premarital women above 16-year old, and HPV vaccination education for student is necessary. These variables explained 25.0% of the variance of the Willingness for education about HPV vaccination. Conclusion: The Willingness for education about HPV vaccination among middle or high school teachers could be improved by the emphasis of the preception that HPV vaccination is necessary to middle or high school students and is related to the prevention of cervical cancer.

Predictors of Human Papillomavirus Vaccination in Female University Students (여대생의 인유두종바이러스 예방접종 예측요인)

  • Park, Jeong-Sook;Lee, Eun-Joo
    • Women's Health Nursing
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    • v.17 no.4
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    • pp.346-358
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    • 2011
  • Purpose: The purpose of this study was to identify predictors of HPV (Human papillomavirus) vaccination among female university students. Methods: The participants in this study were 1,486 female university students. Data were collected using self-administered questionnaire from september 1, 2010 to June 30, 2011. Data were analysed using descriptive statistics, t-test, $x^2$-test and logistic regression. Results: The rate of HPV vaccination was 7.2%. Factors that influence HPV vaccination included residential region, smoking experience, family history of cervical cancer, experience having heard about the HPV vaccination, awareness that HPV is a sexual disease, HPV knowledge, perceived seriousness, perceived benefit and perceived barrier in health beliefs. Conclusion: The results suggest a need to increase HPV vaccination campaigns to increase awareness of HPV vaccination. University and health care facilities should provide health education emphasizing perceived seriousness and perceived benefits. Also, the national health insurance corporation should consider addressing cost issues as a barrier to HPV vaccination.

Effects of Human Papillomavirus Vaccination Education on College Women's Knowledge, Health Belief, and Preventive Behavior Intention (여대생에게 실시한 인유두종 바이러스 예방접종 교육의 효과)

  • Lee, Eun-Jee;Kim, Hyeon-Ok
    • Journal of Korean Academy of Nursing
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    • v.41 no.5
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    • pp.715-723
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    • 2011
  • Purpose: This study was done to evaluated the effects of Human Papillomavirus (HPV) vaccination education on college women's knowledge of HPV, health beliefs (perceived severity and perceived susceptibility), and preventive behavior intention. Methods: A nonequivalent control group pretest-posttest design with repeated measures was used. Participants were 125 female college students in one university, assigned to an experimental group (72 students) and control group (53 students). Results: Two weeks after the intervention, the experimental group reported higher scores of knowledge, perceived severity, perceived susceptibility, and preventive behavior intention than the control group. All follow-up scores except intention measured at 5 weeks after the intervention from the experimental group remained still higher than those from the control group. Conclusion: The results suggest that the variable of preventive behavior intention which is believed to be the closest predictor of real vaccination rate could be affected by the education, but did not remain at the same level at 5 weeks. Therefore, additional interventions may need to be provided before the educational effect on preventive behavior intention is greatly diminished.

Factors Associated with Human Papillomavirus related Stigma, Shame, and Intent of HPV Test (인유두종 바이러스와 관련된 낙인, 수치심과 검사의도의 영향요인)

  • Kim, Hae-Won
    • Journal of Korean Academy of Nursing
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    • v.42 no.2
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    • pp.217-225
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    • 2012
  • Purpose: This study was conducted to examine the factors associated with HPV (Human Papillomavirus) related stigma, shame and intent to have HPV test among adult women. Methods: Data were collected from December 1, 2009 to January 31, 2010, and participants were 324 women who visited an obstetric gynecologic clinic. They anticipated testing positive for HPV. Then HPV related stigma, shame, intent to have HPV testing and HPV knowledge were measured. Descriptive statistics, Mann-Whitney U test, Kruskal Wallis test and multivariate adjusted logistic regression were used for data analysis. Results: The levels of stigma and shame were higher than average. Intent to have HPV test was high and HPV knowledge was low. Women who answered that HPV is not sexually transmitted had lower HPV stigma than did women who answered they didn't know (OR=0.20, 95%CI 0.06-0.68). Women with lower stigma showed lower intent to have HPV test than women with higher stigma (OR=0.46, 95%CI 0.26-0.82). Conclusion: Basic HPV information should be fully understood for women especially prior to HPV test. Normalizing HPV stigma is necessary for women who perceive HPV as sexually transmitted and women intending to have HPV test.