• Journal of the Korean Society for Precision Engineering
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• v.22 no.11 s.176
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• pp.182-189
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• 2005

The human knee joint is the intermediate joint of the lower limb that is the largest and most complex joint in the body. Understanding of joint-articulating surface motion is essential for the joint wear, stability, mobility, degeneration, determination of proper diagnosis and so on. However, many studies analyzed the passive motion of the lower limb because of the skin marker artefact and some studies described medial and lateral condyle of a femur as a simple sphere due to the complexity of geometry. Thus, in this paper, we constructed a three-dimensional geometric model of the human knee from the geometry of its anatomical structures using non-uniform B-spline surface fitting as a study for the kinematic analysis of more realistic human knee model. In addition, we developed and verified 6-DOF contact model of the human knee joint using $C^2$ continuous surface of the inferior region of a femur, considering the relative motion of shank to thigh during locomotion.

• Progress in Medical Physics
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• v.6 no.2
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• pp.111-125
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• 1995

The stress distribution of bone is altered by the rigid bone plate, sometimes resulting in unfavorable osteoporosis. The rigidity and the biocompatibility are important factors for the design of prosthesis, however, it is also necessary to consider the effect on the bone remodeling. In this paper, it is attempted to establish an approximate and simple method to predict the trend of the configuration of surface bone remodeling upon a bone plate using stress analysis. Thus, three dimensional finite element model of plated-human femur is generated and simulated. In addition, the stress difference method (SDM) is introduced and attempted to demonstrate the configuration of surface bone remodeling of the plated-human femur.

• Biomaterials and Biomechanics in Bioengineering
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• v.5 no.1
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• pp.25-35
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• 2020

We carry the knowledge that the skeleton bones of the human body are not always without defects and some various defects could occur in them. In the present paper, as the first endeavor, free vibration and buckling analysis of femur bones with femoral defects are investigated. A major strength of this study is the modeling of defects in femur bones. Materialise Mimics software is adopted to model the bone geometry and the SOLIDWORKS software is used to generate the defects in bones. Next, the ABAQUS software is employed to study the behaviors of bones with defects.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.10a
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• pp.1081-1084
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• 2002

In this study, we perform 3-D reconstruction of human proximal femur from DICOM files by using voxel mesh algorithm. After 3-D reconstruction, the model converted to Finite Element model which developed for automatically making not only 3-D geometrical model but also FE model from medical image dataset. During this job, trabecular pattern, one of characteristic of human bone can be added to the model by means of giving it's own elastic property calculated from intensity in CT scanned image to the each voxel. And then another model is made from same image dataset which have two material properties - one corresponds to cortical bone, another to trabecular bone. Finally, validity of voxel mesh technique is verified through comparing results of FE analysis, free vibration and stress analysis.

• Journal of Biomedical Engineering Research
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• v.24 no.3
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• pp.233-239
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• 2003

Falling related injuries are categorized as the most serious and common medical problems experienced by the elderly, hip joint fracture, one of the most serious consequences of falling in the elderly, occurs in only about 1% of falling. Nevertheless, hip fracture accounts for a considerable part of the disability, death, and medical costs associated with falling. In this study, we considered the impact angle and displacement rate in falling as another factor affecting femoral strength. Using a fresh-frozen human femur, we developed system to simulate the falling condition and then conducted the experiments changing the impact angle (0$^{\circ}$, 15$^{\circ}$, 30$^{\circ}$) of proximal femur. Also, in order to analyze the relative risk due to falling to normal situation in proximal femur, we did the static test simulating the two-legged stance condition. The results showed that the change in impact angle affected the strain distribution in proximal femur, and that a large deformation in femoral neck than in other sites. Furthermore despite low impact velocity, a large deformation in proximal femur occurred in the impact test and different strain distribution was observed compare to the static case.

• Korean Journal of Human Ecology
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• v.4 no.2
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• pp.84-93
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• 2001

This study was to evaluate the effect of dietary taurine on bone mass loss in ovariectomized rats. Forty Sprauge-Dawly female rats (body weight 200$\pm$22 ) were divided into four groups. Control (sham) group was fed without taurine and the other three ovariectomized groups were fed the diets with 0%, 1% and 2% taurine for eight weeks. There was no significant difference in Plasma taurine level among the three ovariectomized groups. The sham group showed higher calcium level in femur than that of the other ovariectomized groups. There was no significant difference in phosphorus level in femur among the four groups. The levels of magnesium and zinc in sham group was higher than those of in the ovariectomized groups. The sham and 1% taurine fed ovariectomized group showed higher level of sodium than 0% and 2% taurine fed ovariectomized groups. Body weight and diet intake in sham group were lower than those of in the three ovariectomized groups due to ovariectomy. Breaking force and specific gravity of femur were not different significantly among the four groups. The level of minerals in l% taurine fed ovariectomized group was higher than that of in 0% taurine fed ovariectomized group even though the level of minerals in ovariectomized was lower than In sham group, which indicates that taurine supplementation might have benificial effects on osteoporosis.

• Journal of the Korean Society for Precision Engineering
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• v.22 no.11 s.176
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• pp.190-195
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• 2005

A Femur is the longest and largest bone which supports body in human musculoskeletal structure. Therefore, it may cause heavy loss of blood when it is suffered by a simple or complex fracture, and the complication is very dangerous with a possibility of severe tissue damage. In this study, the femoral cancellous angle change is estimated in order to design the Korean femoral IM nail. Generally, it is various in the size and curvature of femoral cancellous bone depending on patient's body dimension. Therefore surgeon has difficulty in fitting this femoral IM nail to the patient in the surgical procedure. In our study, we tries to estimate femoral lateral curve angle with more precise method based on CT image of the femur and utilize this information on the design of femoral IM nail for Korean patients.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.10
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• pp.1139-1145
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• 2014

Creation of a human skeleton model and characterization of the variation in the bone shape are fundamentally important in many applications of biomechanics. In this paper, we present a parametric shape modeling method for femurs that is based on extracting the main parameter of variations of the femur shape from a 3D model database by using statistical shape analysis. For this shape analysis, principal component analysis (PCA) is used. Application of the PCA to 3D data requires bringing all the models in correspondence to each other. For this reason, anatomical landmarks are used for guiding the deformation of the template model to fit the 3D model data. After subsequent application of PCA to a set of femur models, we calculate the correlation between the dominant components of shape variability for a target population and the anatomical parameters of the femur shape. Finally, we provide tools for visualizing and creating the femur shape using the main parameter of femur shape variation.

• Journal of the Korean Society of Radiology
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• v.7 no.5
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• pp.359-364
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• 2013

Femur is the largest bone in the human body which supports the weight of body. A long pipeline shape of femur has little cancellous bone, so that regeneration is difficult when fracture happens. The fracture caused by an accident most frequently occurs at diaphysis. IM Nailing is the surgical method that implants an IM Nail into a medullary cavity for the fixation of fracture parts. However, a secondary fracture may happen if an IM Nail does not penetrate at the center of femur. In this study, a patient-specific femur was manufactured by a 3D printer using the computed tomography images scanned before surgery, which was used for the simulation of IM Nailing. It is expected that this result may prevent the secondary damage, reduce surgical operation time, and increase the precision.

• Anatomy and Cell Biology
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• v.57 no.2
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• pp.294-304
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• 2024

Type 2 diabetes mellitus is increasingly becoming more prevalent worldwide together with hospital care costs from secondary complications such as bone fractures. Femoral fracture risk is higher in diabetes. Therefore, this study aimed to assess the osteometric and microarchitecture of the femur of Zucker Diabetic Sprague-Dawley (ZDSD) femur. Ten-week-old male rats (n=38) consisting of 16 control Sprague-Dawley (SD) and 22 ZDSD rats were used. The rats were terminated at 20 weeks and others at 28 weeks of age to assess age, diabetes duration effects and its severity. Bilateral femora were taken for osteometry, bone mass measurements and micro-focus X-ray computed tomography scanning to assess the trabecular number (TbN), thickness (TbTh), spaces (TbSp), bone tissue volume to total volume (BV/TV) and volume (BV). Diabetic rats had shorter (except for 20-weeks-old), lighter, narrower, and less robust bones than SD controls that wered more robust. Although cortical area was similar in all diabatic and control rats, medullary canal area was the largest in ZDSD rats. This means that the diabetic rats bones were short, light and hollow. Diabetic rats aged 20 weeks had reduced BV, BV/TV, TbN with more spacing (TbSp). In contrast, the 28 weeks old diabetic rats only showed reduced BV and TbN. Discriminant function analysis revealed, for the first time, that osteometric parameters and TbTh, TbN, and TbSp were affected by diabetes. This knowledge is valuable in the management of diabetic complications.