• Title/Summary/Keyword: Human Exposure

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Comparison of the Standard Floor Impact Source with the Human Impact Source (표준충격원과 실충격원의 특성 비교)

  • Lee, Pyoung-Jik;Jeong, Jeong-Ho;Jeon, Jin-Yong;Park, Jun-Hong
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2005.11a
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    • pp.804-807
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    • 2005
  • The characteristics of the standard floor impact sources and the human impact source were investigated. First, the mechanical impedance of the each source was evaluated. Second, the impact force exposure levels and impact sounds level driven by the each source were measured. The results showed that the mechanical impedance and impact force exposure level of the impact ball are the most similar to those of the human impact source among the standard impact sources.

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Effects of Regular Jjimjilbang(Korean sauna) Exposure on Human Heat Tolerance in Young and Old Females (정기적인 찜질 훈련이 청년과 노년여성의 내열성 증진에 미치는 영향)

  • Choi, Jeong-Wha;Song, Eun-Young;Hwang, Soo-Kyung
    • Journal of the Korean Society of Clothing and Textiles
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    • v.31 no.9_10
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    • pp.1465-1474
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    • 2007
  • We analyzed the effects of regular Jjimjilbang(Korean sauna) exposure on the heat tolerance in young and old females. Subjects were young(n=7) and old(n=7) females who never had a bath in Jjimjilbang for last year. Jjimjilbang training group took a bath in Jjimjilbang once a week 19 times. Jjimjibang expsure was limited three times per day, Jjimjil were taken free way. To prove the effects of the heat tolerance, Subjects were exposed to hot and humid air$(40.0{\pm}0.5^{\circ}C,\;60{\pm}5%RH)$. In the condition, subjects were taken a foot bathing$(40.0{\pm}0.5^{\circ}C)$ and simulated for 30 min., and rectal temperature, skin temperatures, clothing microclimate, blood pressure, total body weight loss, local sweat and subjective sensation were measured. The results are as follow: Rectal temperature, skin temperatures, clothing microclimate, total body weight and subjective thermal comfort sensation were decreased gradually(p<.001). Local sweat of upper arm was decreased(p<.01). In conclusion. the regular Jjimjilbang exposure has positive effects upon improvement in regulation of body temperature, especially in heat tolerance.

Antiproliferative effect of Citrus junos extracts on A549 human non-small-cell lung cancer cells

  • Geum-Bi Ryu;Young-Ran Heo
    • Journal of Nutrition and Health
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    • v.56 no.1
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    • pp.12-23
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    • 2023
  • Purpose: This study investigates the alterations in A549 human non-small-cell lung cancer (NSCLC) cells exposed to Citrus junos extract (CJE). We further examine the antiproliferative and apoptotic effects of CJE on NSCLC cells. Methods: Inhibition of proliferation was examined by applying the 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT) colorimetric assay on CJE-treated A549 NSCLC cells. The lactate dehydrogenase (LDH) assay was performed to measure the degree of toxicity of CJE on NSCLC cells. The effect on migratory proliferation was confirmed using the scratch wound healing assay. The antiproliferative effect of the CJE on human lung cancer cells was verified through morphological observation, fluorescence microscopy, and caspase-3 colorimetry. Results: Exposure of NSCLC cells to CJE resulted in a dose- and time-dependent decrease in cell activity and increased toxicity to the cells. In addition, microscopic observation revealed a reduced ability of the cancer cells to migrate and proliferate after exposure to the CJE, with simultaneous morphological apoptotic changes. Fluorescence staining and microscopic examination revealed that this death was a process of self-programmed cell death of NSCLC cells. Compared to unexposed NSCLC cells, the expression of caspase-3 was significantly increased in cells exposed to CJE. Conclusion: Exposure of A549 human NSCLC cells to CJE inhibits the proliferation, increases the cytotoxicity, and decreases the ability of cells to migrate and grow. Moreover, the expression of caspase-3 increases after CJE treatment, suggesting that the apoptosis of NSCLC cells is induced by a chain reaction initiated by caspase-3. These results indicate that Citrus junos is a potential therapeutic agent for human non-small-cell lung cancer.

Worker's exposure assessment of cyclonite in explosive compounds and bomb manufacturing companies (폭약 및 폭탄 제조시 발생하는 시클로나이트의 작업자 노출수준 평가)

  • Jeong, Jee Yeon;Lee, Jee Hyeon;Kim, Eun Young;Lee, Seung Hoon
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.21 no.1
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    • pp.55-61
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    • 2011
  • Cyclonite is a white powder and is very explosive. It can cause seizures (a problem of the nervous system) in human and animals when large amounts are inhaled or eaten. Research papers for workers exposure assesment of the cyclonite are very a few in the world. A field study was conducted at explosive compounds and bomb manufacturing companies to evaluate workers exposure to cyclonite. The airborne average concentration of cyclonite in explosive compounds manufacturing company was $4.10{\mu}g/m^3$(range: ND - $59.92{\mu}g/m^3$), and that of cyclonite in bomb manufacturing company was $31.49{\mu}g/m^3$(range: ND - $291.41{\mu}g/m^3$). Package process and assembly process in both companies were considered the high potential of exposure to cyclonite. Even though all airborne concentrations of cyclonite were lower than occupational exposure standard (MOEL: $500{\mu}g/m^3$), exposure to cyclonite can also occur through dermal contact during manufacture, handling, and clean-up of cyclonite. So control measures for protecting skin absorption of cyclonite were needed for preventing adverse health effect by cyclonite exposure.

Pesticide Exposure and Health (농약 노출과 건강)

  • Lee, Won-Jin
    • Journal of Environmental Health Sciences
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    • v.37 no.2
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    • pp.81-93
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    • 2011
  • Although pesticides have increased crop production and controlled disease, they have produced a number of adverse health effects. Pesticides have potential human toxicity and a variety of groups, such as farmers or industrial workers, as well as the general population, are exposed to pesticides. The purpose of this article, therefore, is to provide an overview of pesticide exposure and health through a literature review, focusing on exposure assessment, acute poisoning, chronic health effects, and future research needs. The exposure types and levels of pesticides vary by study subjects and need to be assessed by integrating several methods focused on the epidemiological purpose. Acute pesticide poisoning is a major public health problem in the world. Paraquat is the main causative pesticide for acute poisoning in Korea and should be banned in order to save several thousands of lives every year. Occupational pesticide exposure also causes numerous chronic diseases among farmers and industrial workers, including cancers, respiratory diseases, depression, retinal degeneration, diabetes, and abnormal menstrual cycle. However, controversy exists regarding the long-term effects of low-dose environmental pesticide exposure. The area of pesticide study is relatively new with broad study populations and it has received little academic and policy attention, particularly in Korea. More detailed studies investigating the risk of pesticide-related health effects and intervention efforts to reduce the problems are needed in Korea.

The Meaning of Exposure in Red Carpet Fashion of Korean Female Movie Star (한국 여배우의 레드 카펫 패션에 나타난 노출의 의미)

  • Son, Ji-Won;Kim, Min-Ja
    • Journal of the Korean Society of Costume
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    • v.61 no.6
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    • pp.146-160
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    • 2011
  • The purpose of this study is to examine the aesthetic view towards exposure in the Korean society through the means of analyzing the characteristics of exposure and figuring out the implications expressed in the red carpet fashion of Korean female movie stars. The concept of exposure in fashion was reviewed through previous studies and related publications. The pictures of actresses wearing red carpet evening gowns in Korea's major film festival were collected and analyzed. The results indicated that the meaning of exposure expressed in the red carpet fashion of Korean female movie stars are as follows: First, this leads the trend reflecting the contemporary aesthetic view of exposure as an effective way to show the beauty of the female body. Second, this emphasizes the femininity and expresses eroticism by exposing certain body parts which symbolize the female gender. Third, this shows the narcissistic self conspicuousness as well as the self confidence and self satisfaction. Forth, this displays the playfulness through exposing the body in a unique way. Lastly, the way and level of exposure can be used to maintain or change the public's view upon the celebrity.

Effects of Human Activity Patterns on Personal Exposure Levels of Nitrogen Dioxide in A-San Area (아산지역에 있어서의 $NO_{2}$ 개인 피폭량에 미치는 각종 생활행동 패턴의 영향)

  • 손부순;김대선;정문식
    • Journal of environmental and Sanitary engineering
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    • v.11 no.3
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    • pp.47-52
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    • 1996
  • Personal exposure levels of $NO_{2}$ for office workers and housewives Living in A-San and neighboring prefectures were measured in two seasons with $NO_{2}$ filter badge. $NO_{2}$ concentrations in indoor and outdoor air in their offices and houses were also measured in the same periods. Personal exposure levels in winter ranged from 13 to 132 ppb and its distribution pattern was remarkably different from the other seasons (15.2-17.9 ppb). This fact suggests that use of heating apparatus affects largely $NO_{2}$ indoor air pollution in winter seasons. Actually, $NO_{2}$ exposure levels of subjects used Kerosene heater (43.6ppb) and gas heater (33.4ppb) were higher than those of subjects unused heating apparatus (18.0ppb). Personal exposure levels of $NO_{2}$ for man and woman Living in the same houses were correlated well each other. The time spent indoors for office workers and housewives were both longer than 22 hour a day. Home staying time was about 60% of total indoor staying time for office workers and 90% or more for housewives. Personal exposure levels were significantly related to indoor exposure levels at home all seasons. Furthermore, personal exposure levels could be estimated from $NO_{2}$ concentrations and staying times in various Living environment.

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Research on Image Quality and Effective dose by Exposure Index Variation (Exposure Index변화에 따른 Image Quality와 Effective dose에 대한 연구: a Monte Carlo Simulation Study)

  • Kim, Hyun Soo;Jeong, Jae Ho;Lee, Jong Woong
    • Journal of the Korean Society of Radiology
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    • v.7 no.1
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    • pp.63-69
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    • 2013
  • Comparing with film-screen system, flat-panel detector has extensive dynamic range. Focusing flat-panel detector, whole body human phantom PBU-50 (Kyoto, kagaku, Japan) was used to perform comparative study of the estimate of image quality and exposure dose. the exposure condition was 81kV and 20mAs, which is used for Abdomen supine exam in clinical area. As a result of the kV change of the interpreted medical image which has over 30dB of PSNR value, the value of DAP shows the difference of 19.6 times. Moreover, the result of comparing kV change with effective dose of ICRP 103 shows that stochastic effect was increased by over exposure. Therefore, it is significantly necessary that digital radiation technical chart will be used to obtain high quality image and make the standard of dose by educating radio-technologist continually.

The Effects of Regular Jjimjilbang Exposure on Cold Tolerance in Young and Elderly Females (정기적인 찜질방노출이 청년과 노년 여성의 내한성에 미치는 영향)

  • Choi, Jeong-Wha;Song, Eun-Young;Hwang, Soo-Kyung
    • The Korean Journal of Community Living Science
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    • v.18 no.4
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    • pp.599-607
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    • 2007
  • We analyzed the effects of regular Jjimjilbang (Korean sauna) exposure on the cold tolerance in young and elderly females. Subjects were young (n=7) and elderly (n=7) females who had never had Jjimjilbang exposure experience. The Jjimjil training group was exposured in the Jjimjilbang 19 times per week. Jjimjibang exposure was limited to three times per day. Jjimjil activity was taken freely. To prove the effects of the cold tolerance, subjects were exposed to cold air ($12{\pm}1^{\circ}C,\;60{\pm}10%$RH). In these conditions, subjects were exposed for 30 minutes at which time rectal temperature, skin temperatures, clothing microclimate, energy expenditure, blood pressure and subjective sensation were measured. To prove the effects of the local cold tolerance, vascular hunting reaction was observed measuring the finger skin temperature while the left middle finger tip was immersed in cold water of $0^{\circ}C$ for 30 minutes. The results are as follows. According to repeated Jjimjil exposure, rectal temperature changes, peripheral temperature and energy expenditure were increased gradually in the cold climate chamber. Blood pressure, subjective sensation and vascular hunting reactions did not show any significant difference. In conclusion, regular Jjimjilbang exposure has negative effects on the ability of the body to improve its regulation of temperature especially in cold tolerance.

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Adverse Effect of Nonylphenol on the Reproductive System in F1 Male Mice: A Subchronic Low-Dose Exposure Model

  • Kim, Yong-Bin;Cheon, Yong-Pil;Lee, Sung-Ho
    • Development and Reproduction
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    • v.23 no.2
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    • pp.93-99
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    • 2019
  • Nonylphenols (NPs) are widely used industrial materials, and are considered as potent endocrine disrupting chemical. Present study was undertaken to clarify the effect of subchronic low-dose NP exposure to F1 generation male mice. Mice were divided into 2 groups; (1) CON, control animals and (2) NP-50 ($50{\mu}g/L$), animals were treated with NP via drinking water. NP exposures were continuously conducted from parental pre-mating period until the postnatal day (PND) 55 of F1 offsprings. Mice were sacrificed on PND 55 and the tissue weights were measured. The initial body weights (at PND 21) and terminal body weights (PND 55) of the NP-50 animals were significantly lower than those of control animals (p<0.05). NP exposure induced a significant increase in the absolute weight of the testes (p<0.05). Conversely, the NP exposure caused significant decrease in the absolute weights of the epididymis (p<0.01), prostate (p<0.05) and seminal vesicle (p<0.05). Histopathological studies revealed that NP-treated animals exerted decreased seminiferous tubule diameters, reduced luminal area, and lower number of germ cells. Also some sloughing morphologies in the tubules were observed. In the caudal epididymis, fewer mature sperms and swollen epithelial cells were found in the NP-treated group. Our results confirmed that the subchronic low-dose NP exposure altered some male parameters and induced histopathological abnormalities in testis and epididymis of F1 mice. Since the NP dose used in this study is close to the average human daily NP exposure, our results could provide practically meaningful understanding of adverse effect of EDC in human.