• Nuclear Engineering and Technology
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• v.29 no.1
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• pp.78-84
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• 1997

The specific purpose of this study is to develop the numerical guide for the cost-benefit analysis of ORE ($/person-Sv reduction) to meet the criterion of ALARA in the design stage of the KNGR. In deriving the guide, the risk factor which is defined by the risk to unit collective radiation exposure dose (deaths/person-Sv) and the monetary value of human life ($/death) are required. The risk factor has been estimated from various clinical data accumulated for a number of years and continuously modified. And the monetary value of human life is usually quantified using the human capital approach. In this study, the risk to radiation exposure perceived by a group of people is investigated through an extensive poll survey conducted among university students in order to modify the existing risk factor for radiation exposure. And in evaluating the monetary value of human life, the QOL factor is introduced in order to incorporate the degree of public welfare or quality of life. As a result of study, a value within the range of 151, 000~172, 000 dollars per person-Sv reduction is recommended as the appropriate interim numerical guide for cost-benefit analysis of ORE to meet the criterion of ALARA in the design stage of the KNGR. A poll survey was also conducted in order to see whether the public acceptance cost of nuclear power should be incorporated in developing the guide, and the result of study shooed that such a cost does not need to be considered.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3781-3789
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• 2012

Background: Pancreatic cancer is one of the most aggressive tumors with a dismal prognosis. The membrane cytoskeletal crosslinker Ezrin participates in several functions including cell proliferation, adhesion, motility and survival. There is increasing evidence that Ezrin is overexpressed in vast majority of malignant tumors and regulates tumor progression. However, its roles in pancreatic cancer remain elusive. Methods: Three pairs of specific Ezrin siRNAs were designed and synthetized and screened to determine the most efficient one for construction of a hairpin RNA plasmid targeting Ezrin. After transfection into the Panc-1 pancreatic cancer cell line, real-time quantitative PCR and Western blotting were performed to examine the expression of mRNA and protein. The MTT method was applied to examine the proliferation and the drug sensibility to Gemcitabine. Flow cytometry was used to assess the cycle and apoptosis, while capacity for invasion was determined with transwell chambers. Furthermore, we detected phosphorylated-Erk1/2 protein and phosphorylated-Akt protein by Western blotting. Results: Real-time quantitative PCR and Western blotting revealed that Ezrin expression was notably down-regulated at both mRNA and protein levels by RNA interference (P< 0.01). Proliferation was inhibited and drug resistance to gemcitabine was improved (P< 0.05). Flow cytometry showed that the proportion of cells in the G1/G0 phase increased (P< 0.01), and in G2/M and S phases decreased (P< 0.05), with no apparent differences in apoptosis (P> 0.05). The capacity for invasion was markedly reduced (P< 0.01). In addition, down-regulating Ezrin expression had no effect on phosphorylated-Akt protein (P>0.05), but could decrease the level of phosphorylated-Erk1/2 protein (P< 0.05). Conclusions: RNA interference of Ezrin could inhibit its expression in the pancreatic cancer cells line Panc-1, leading to a potent suppression of malignant behavior in vitro. Assessment of potential as a target for pancreatic cancer treatment is clearly warranted.

• Journal of the Korean Home Economics Association
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• v.38 no.7
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• pp.79-92
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• 2000

The purpose of this study is to verify the soundness of homelife and the stress of home management perceived by housewives living in Seoul as well as to investigate how the soundness of home life affects the stress of home management. In total, 914 housewives were studied to serve as a data sources. The major result are as follows : 1. Communication variables huts the strongest effect on the soundness of home life. 2. Wife's self-actualization influences the soundness of home life and home management stress. 3. Wife's internal-external control has an positive effect on the soundness of home life and home management stress. 4. The soundness of home management variables-family unification, time, psychological health, human ability, physical health should be developed as human capital.

• International Journal of Human Ecology
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• v.12 no.1
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• pp.37-49
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• 2011

This article addresses potential barriers to sustained employment for rural low-income mothers. Drawing from a two panel longitudinal sample of 240 families from the Rural Families Speak project, it examines the extent to which human capital and family factors were related to these mothers' ability to be employed. Comparisons are made between mothers, who over a three-year period, were continuously unemployed, intermittently employed, or stably employed. Many of these rural low-income mothers faced multiple individual and family barriers that impacted their labor force participation. Notably food insecurity, mental health, caring for a young child, housing, and a family history of welfare were associated with less stable employment. The implications for public policy and service delivery are discussed.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.32 no.4
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• pp.128-133
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• 2009

Brain drain of scientists and technologists to the United States from other countries is a phenomenal issue due to the potential developmental impacts it could have on sending countries. Immigration policies undoubtedly play the major part to shape the human resource outcomes. There has been a common sense explanation to the brain drain trend, which states that the lower English language requirements in the scientific and technology jobs compared to other high skill brain drain jobs offer immigrants more favorable employment opportunities. These and other language related variables are used with standard human capital model variables to assess the validity of the common sense proposition.

• International Journal of Computer Science & Network Security
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• v.21 no.5
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• pp.133-138
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• 2021

The concept of inclusive development provides equal opportunities for all participants in access to the labor market and resource allocation. This concept emphasizes the equality of human capital, the ecological state of the environment, social protection and food security. This concept is fundamentally different from the standard perception of economic growth, because it has broader goals than simply increasing incomes and GDP. It rejects the position that positive results are an automatic consequence of growth; here the basic condition is human development and increase of its well-being, reduction of poverty. Therefore, it is not the result of distribution that becomes primary, but the involvement in the process of social reproduction. An alternative system of characterization of the country's position according to the resulting indicator of the Inclusive Development Index was presented at the World Economic Forum in Davos. In this research the methodical development of the system of estimation of the index of inclusive development for regions of the NUTS 4 level of the European classification is resulted.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2022.06a
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• pp.357-358
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• 2022

Seafarers from 21 APEC economies, are not only an indispensable source of human capital for the global maritime industry, covering at least 56% of the world's seafaring population (BIMCO, 2015), but also pivotal in providing support to their economies as a major industrial pillar, specifically in developing economies where the development of skills and enhancement of labor mobility of human resources is essential in creating sustainable and inclusive regional growth. This paper examines challenges and barriers in seafarer mobility in relation to policies in APEC economies and investigates mutual collaborative actions that can be taken to address the issues identified in a coordinated and harmonised manner.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.9 no.5
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• pp.13-20
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• 2014

This study drew a conclusion about the current situation and the trend of start-up in Korea by understanding the convenience of start-up and startup outcome(business satisfaction and income after startup) by year, and by analyzing the trend of the convenience of start-up by each detail items and by industry. In addition to, the key factors of successful business start-up are demonstrated by synthetically examining how the factors influence the outcome of startup, including human capital, business characteristics, economic feature, and situational/institutional characteristics, as well as demographic characteristics. According to the result, business satisfaction after startup by year and business income have gradually increased from 2005, but the convenience of start-up has constantly decreased. Based on the industry, the convenience of start-up shows a statistical significance. Lastly, the factors that influence the outcome of business start-up are complexly turned up as human capital, business characteristics, economic feature, and situational/institutional characteristics, as well as demographic characteristics.

• Journal of Digital Convergence
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• v.13 no.11
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• pp.449-459
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• 2015

The purpose of this study was to examine demographic, human capital and service factors affecting employment outcomes of people with hearing impairments. The total of 422 individuals (age from 20 years to 65 years) with hearing impairments were collected from the Panel Survey of Employment for the Disabled from Korea Employment Agency for the Disabled. The dependent variable is employment outcomes. The predictor variables include a set of personal history, human capital and rehabilitation service variables. The chi-squared automatic interaction detector (CHAID) analysis revealed that the status of the national basic livelihood security played a determining role in predicting the employment of people with hearing impairments. Also, it was found that the three factors of the status on the national basic livelihood security, needed help about activities of dailey living, licenses & employment service factors created bigger synergy effect when they inter-complemented one another.

• The Journal of the Korea Contents Association
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• v.14 no.5
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• pp.144-155
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• 2014

This study aims to overcome the limitations of prior studies that have failed to take into account the impact of psycho-social factors on the employment of people with disabilities as well as the differences in employment by life stage. This study employs a research model that includes psycho-social factors along with human capital to examine how the determinants of employment differ for the disabled by life stage. The analysis in this study takes the form of logistic regression, using data from the fifth wave of the Korea Welfare Panel Survey. Analysis results show that the employment probability of young people with disabilities is significantly associated with their experience of discrimination, with their chance of employment decreasing when they have more experience of discrimination. Middle-aged people with disabilities are more likely to be employed when they have a lower level of education, a better health condition and a higher level of labor ability. For the disabled elderly, their labor ability is the only factor affecting their possibility of employment; they have a higher chance of getting a job when they have a higher level of labor ability.