• Journal of the East Asian Society of Dietary Life
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• v.13 no.3
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• pp.167-175
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• 2003

This study was conducted to investigate the actual state of the food allergy and food behavior in adults by using a questionnaire. The subjects of this study were consisted of 207 males and 355 females in Gyeongbuk area. The results are as follows: Among the respondents, 54.9% kept up with proper eating habits, 41.2% knew how much they would have to eat appropriately in a day, and women ate more milk and snacks than men in a day and men ate more meat than women. 58.3% of men and 46% of women were eating 3 meals a day. This finding indicated that women skipped the meal more than men. 77.2％ of the respondents skipped their breakfast, 13.5％ the lunch, and 9.3% the dinner. 48.5％ of men and 28.8% of women evacuated over 8 times a week(p<0.001). Eczema was the allergy symptom which broke out the most highly in both male and female; 25% of men and 29.9% of women. Atopic dermatitis and pollen allergy broke out similarly in both male and female. Allergic rhinitis occurred twice more in men than in women. Asthma broke out in men about three times more than in women. 36.3% of men and 46.5% of women visited a doctor when they had an allergic reaction. 40.9% of men and 40.7% of women believed that the allergy was caused mainly by the dust in the house and mites. The other factors, which caused the allergic reaction, were thought to be the specific food and the pollution from cars and factories by men and the specific food and others by women. 35.4% of men and 44.2% of women ate homemade food to prevent allergies.

• The Korea Journal of Herbology
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• v.30 no.5
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• pp.45-49
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• 2015

Objectives : The aim of this study is to investigate anti-inflammatory activity using various extracts of rice straw (DaoCao) extract (RS).Methods : To investigate the anti-inflammatory effect of RS, we examined the effect of RS on cytokines production on THP-1 cell. Cells were cultured in incubator (37℃, CO₂5%, 0.5% FBS-RPMI, 1X10⁶cells/ml). One hour after,Dermatophagoides pteronissinus(Dp., 10 ug/ml) was treated into cell and at 6 hour after, each different concentrations(0.1, 1 and 10 ug/ml) of RS were treated. The cells were incubated for 16 hours and harvest the supernatant. The levels of IL-4, IL-5, IL-6, IL-8, MCP-1 and TNF-αwere determined using a commercially available ELISA kit.Results : We investigated whether RS has the inhibition of inflammatory response in Jurkat cells and THP-1 cells. RS suppressed secretion of IL-4, IL-5, and TNF-αinduced by house dust mites in Jurkat cells. It showed significant effects for all concentrations. RS suppressed the increased expression of IL-6, IL-8 and MCP-1 after treatment with mite in THP-1 cells. These results suggest that RS may be used as a valuable agent for treating allergic diseases such as atopy due to its anti-inflammatory property.Conclusions : RS showed significant biological activities with anti-inflammatory in the human T cells. These results suggest that RS may be used as a valuable agent for treating allergic diseases such as atopy due to its anti-inflammatory property. In terms of Korean traditional medicine, we expect the results to contribute to building of EBM (Evidence-Based Medicine).

• The Journal of Internal Korean Medicine
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• v.26 no.2
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• pp.467-474
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• 2005

The main symptoms of allergic rhinitis are sternulation, rhinorrhea and rhinanchon. It is also characterized by frontal headache, ohotophobia and epiphora. Alleric rhinitis occurs when inhaled alleren is in contact with nasal mucosa which causes immune response. Bojungiki-Tang is one of the most frequently used medical treatment for the allergic rhinitis. Two chronic perennial allergic rhinitis sutterers, whose alleraies are thought to be due to house dust and ticks, were investigated through the eosinoohil numerical index and the subject symptom numerical index for three months. After treatment, both patients showed a lower index for both tests. The symptom index scores diminished from 17 to 3, and from 16 to 5. The eosinophil numerical index taken through blood tests, diminised from 4 to 2, and from 4 to 3. The above results suggest that Bojungiki-Tang has the inhibitory effects on allergic rhinitis.

• The Journal of Korean Medicine
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• v.24 no.4
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• pp.64-70
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• 2003

Background and Purpose : Allergic rhinitis is a well-known, relatively controllable chronic disease. Although a number of methods for treating allergic rhinitis have been tried, many patients have not been satisfied with their treatment. Therefore, this study tried to evaluate the effect of a cooperative system of Oriental and Western medicine and to develop a new diagnosis protocol for treatment of allergic rhinitis. Methods : We measured improvement rate and acoustic rhinometry after the allergeninduction test and performed a filter paper test as a nonspecific hypersensitivity test with 60 patients who are allergic to house dust mite. Patients were divided into two groups, one treated with Western medicine only and one treated with both Western and Oriental herbal medicine. For the group with Western medicine only, antihistamine for one week and local steroid medicine for two weeks were prescribed. For the group with combined medicine, Oriental herbal medicine was prescribed according to the patient s constitution, along with Western medicine. After all treatments, the above tests were re-performed and the improvement rate was compared. Results and Conclusion : We observed better results in the group treated with both Western and Oriental herbal medicines, comparing improvement rate and the alteration of total nasal volume through acoustic rhinometry after the allergen induction test. In the filter paper test, there was no significant difference between the two groups. In conclusion, we showed the additive effect of Oriental herbal medicine without any severe side effects compared with treatment with Western medicine only. In this study, we set only two patient groups, but further study is required to create various experimental groups and compare among them. We suggest that it might enhance understanding of the improved effect of Oriental herbal medicine in the therapy of allergic rhinitis.

• Journal of the Korean housing association
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• v.26 no.1
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• pp.61-70
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• 2015

The purpose of this study was to provide information on how to expend participation in and raise awareness of the Green Parking Project. A survey was conducted for this study among two groups. One group consisted of 38 residents of the Green Parking Zone in Nam-gu, Ulsan, and the other group consised 129 residents with no experience with the Green Parking Project. For analysis, the frequency and means were calculated, and t-test, analysis of variance, and chi-square test were performed. The results showed, first, that general residents tended to think that parking on the street in front of one's house is a divine right, while residents living the Green Parking Zone thought that the street is a public space. Second, general residents regarded fences as means of security to protect their private property, while people living in the Green Parking Zone tended to think of their yards as semi-private spaces and allowed access to neighbors. Third, general residents had concerns about maintenance and administration fees, noise and dust, security of houses, and privacy. However, residents of the Green Parking Zone evaluated those conditions positively. Fourth, people who were well-informed about the Green Parking Project had low anxiety about security and invasion of privacy, results from the project. Therefore, effective public relations are very important for expanding participation and raising awareness.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1982.05a
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• pp.16.3-17
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• 1982

Nasal polyps were apparently common in many parts of the world and treated for nearly three thousand years. Nasal polyps are round, smooth, soft, semi-translucent, yellow or pale glistening structures, usually attached to the nasal or sinus mucosa by a relatively narrow stalk or pedicle. The incidence of nasal polyps is increased in patients with atopic diseases; it varies from 15% to 25% and now increased using allergy therapy for nasal polyposis treatment. Sinusitis is an inflammation of the mucous membranes of the sinuses. Many agents can cause an inflammatory response, including organisms such as bacteria and viruses, physical and chemical trauma, and antigen antibody reactions. The role of antigen antibody interactions (allergy) in simusitis is not completely understood ; however, patients with allergic rhinitis and nasal polyps have a high incidence of sinusitis. Recently authors have experienced two cured cases of nasal polyposis combined with chronic sinusitis by allergy therapy, that cases were treated only allergy thereapy after Caldwell Luc operation with ethmoidectomy and polypectomy. At now cases were not recur of nasal polyps and nasal symptoms. So the cases were reported with a brief review of literature.

• Journal of Food Hygiene and Safety
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• v.31 no.3
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• pp.201-209
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• 2016

Many atmospheric pollutants including chemical agents, house dust, and microorganisms cause building-related illnesses through respiration in humans. This study was conducted to analyze the profiles of microbial pollutants in air purifiers used in home, office and playschool. Dominant eleven species of microorganisms were isolated and identified in environmental air and air purifiers. Among them, Staphylococcus sp., Micrococcus sp. and Bacillus sp. are the most dominant species. By phylogenetic analysis of the 16S rRNA gene, the dominant bacteria were identified as Staphylococcus epidermidis, Micrococcus luteus and Bacillus epidermidis, respectively. It has been known that these bacterial species are closely related with food spoilage and human infectious disease. Thus, these results indicate that microbial pathogens related with human illnesses through respiration will be contaminated in air purifiers and also need to develop a method to control those of pathogens for human health.

• Proceedings of the Korea Contents Association Conference
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• 2017.05a
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• pp.105-106
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• 2017

Background: Atopic dermatitis one of the most common chronic skin diseases, is caused by various environmental and genetic factors. Methods: A total of 2609 healthy newborns who were enrolled in the COCOA study (COCOA) from 2008 to 2015 were surveyed for indoor environmental exposure to fungi during gestation and then diagnosed postnatally for atopic dermatitis. The fungi collected during the gestation of 20 normal subjects and 20 infants that developed atopic dermatitis were identified using Illumina's MiSeq platform and analyzed for their diversity and species. Results: A total of 2,609 respondents were surveyed (52.8% male and 47.2% female) Children, 1, 2, and 3 years old diagnosed with atopic dermatitis comprised 15.2%, 15.7%, and 14.1% of the respondents, respectively. The prevalence of exposure to mold during gestation was 1.46 (95% CI, 1.05-2.04) and 1.52 (95% CI, 0.95-2.43), in the first and third years after birth, respectively. One-year-old children with atopic dermatitis and no fungal markers detected in the bathroom environment during gestation accounted for less than 5% (aOR, 1.51; 95%CI, 0.96-2.38) and in the group less than 5 ~ 30% (aOR, 2.21; 95%CI, 1.00-4.89), 3-year-old children had an increased prevalence of atopic dermatitis of more than 30% (aOR, 9.48, 95%CI 1.42-63.13). Conclusions: Exposure to indoor fungi during gestation and infancy is associated with the development of atopic dermatitis in children. The phyla and genera of the fungi in the indoor house dust differed during gestation. This suggests that exposure to indoor fungi during gestation may be associated with the development of atopic dermatitis in children. Future research will be necessary to establish the underlying mechanisms.

• Korean Journal of Clinical Laboratory Science
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• v.48 no.2
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• pp.102-108
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• 2016

Der p 2 is the major allergen of the house dust mite (HDM) associated with the development of allergic diseases. The pathogenic mechanism of the allergy is related to cytokine release of lymphocytes and constitutive apoptosis of neutrophils. In the present study, we examined whether Der p 2 induces cytokine release of lymphocytes, which is involved in regulation of neutrophil apoptosis. In normal and allergic subjects, Der p 2 enhanced the secretion of IL-6, IL-8, MCP-1, and GM-CSF in a time-dependent manner. Although Der p 2 was weakly effective against neutrophil apoptosis, conditioned media collected from normal and allergic lymphocytes after Der p 2 treatment inhibited the apoptosis of normal and allergic neutrophils. Der p 2 showed stronger inhibition of apoptosis of allergic neutrophils cocultured with allergic lymphocytes than normal neutrophils cocultured with normal lymphocytes. These findings improve our understanding of the role of Der p 2 in regulation of lymphocytes and neutrophils and will enable elucidation of allergy pathogenesis.

• The Korean Journal of Food And Nutrition
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• v.33 no.2
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• pp.174-182
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• 2020

Probiotics improve the immune system. However, the effects of its lactic acid bacteria on atopic dermatitis relief and inflammation improvement is not fully understood. Recently, one of the probiotics, Lactobacillus helveticus HY7801 (HY7801), was found to have an anti-inflammatory effect. In this study, we investigated the effects of HY7801 on atopic dermatitis-induced animal models. After four weeks of oral administration, the group treated with HY7801 showed amelioration of the atopic dermatitis compared to the group receiving placebo. In the HY7801 treated group, the epidermal hyper-proliferation and collagen deposition were inhibited compared to the placebo group, and the secretion amount of the inflammatory factors, such as TNF-α, IL-4 were reduced. In conclusion, these results suggest that HY7801 acts as a functional probiotic via amelioration of the atopic dermatitis such as a decrease of epidermal hyper-proliferation, and collagen deposition and anti-inflammatory effects.