• 제목/요약/키워드: Host selection

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The Determinants of Foreign Subsidiary CEO Selection: Effects of Internal and External Network Embeddedness of Foreign Subsidiaries and Market Characteristics of Host Country

  • Lee, Jae-Eun;Yang, Young-Soo
    • Journal of Korea Trade
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    • 제25권2호
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    • pp.134-151
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    • 2021
  • Purpose - This study empirically analyzes the impact of the internal and external network embeddedness of foreign subsidiaries and local market characteristics of the host country on the CEO selection whether or not to appoint an expatriate as the CEO of a foreign subsidiary. Design/methodology - To conduct an empirical analysis, we obtained a list of the headquarters of Korean MNCs from the Korea Chamber of Commerce and Industry. Based on the list of HQs, we identified a final list of overseas subsidiaries of Korean MNCs that have entered the world from KOTRA (Trade-Investment Promotion Agency for Korea). Then we conducted an empirical analysis based on the results of 391 questionnaires by employing logistic regression analysis. Findings - The results of empirical analysis are as follows. First, the higher the subsidiary's internal network embeddedness, the higher the tendency appoint an expatriate as the CEO. Second, the higher the volatility of the local market, the higher the tendency to appoint an expatriate as the CEO. Third, the stronger the competition in the local market, the lower the tendency to appoint a PCN. Originality/value - This study has significant theoretical implications in that it examines the link between the internal and external embeddedness of overseas subsidiaries and the appointment of parent country nationals (PCNs) as the CEO that prior research has not examined.

Evaluation of Various Escherichia coli Strains for Enhanced Lycopene Production

  • Jun Ren;Junhao Shen;Thi Duc Thai;Min-gyun Kim;Seung Ho Lee;Wonseop Lim;Dokyun Na
    • Journal of Microbiology and Biotechnology
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    • 제33권7호
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    • pp.973-979
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    • 2023
  • Lycopene is a carotenoid widely used as a food and feed supplement due to its antioxidant, anti-inflammatory, and anti-cancer functions. Various metabolic engineering strategies have been implemented for high lycopene production in Escherichia coli, and for this purpose it was essential to select and develop an E. coli strain with the highest potency. In this study, we evaluated 16 E. coli strains to determine the best lycopene production host by introducing a lycopene biosynthetic pathway (crtE, crtB, and crtI genes cloned from Deinococcus wulumuqiensis R12 and dxs, dxr, ispA, and idi genes cloned from E. coli). The 16 lycopene strain titers diverged from 0 to 0.141 g/l, with MG1655 demonstrating the highest titer (0.141 g/l), while the SURE and W strains expressed the lowest (0 g/l) in an LB medium. When a 2 × YTg medium replaced the MG1655 culture medium, the titer further escalated to 1.595 g/l. These results substantiate that strain selection is vital in metabolic engineering, and further, that MG1655 is a potent host for producing lycopene and other carotenoids with the same lycopene biosynthetic pathway.

Interactions between secreted GRA proteins and host cell proteins across the parasitophorous vacuolar membrane in the parasitism of Toxoplasma gondii

  • Ahn, Hye-Jin;Kim, Sehra;Kim, Hee-Eun;Nam, Ho-Woo
    • Parasites, Hosts and Diseases
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    • 제44권4호
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    • pp.303-312
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    • 2006
  • Interactions between GRA proteins of dense granules in Toxoplasma gondii and host cell proteins were analyzed by yeast two-hybrid technique. The cMyc-GRA fusion proteins expressed from pGBKT7 plasmid in Y187 yeast were bound to host cell proteins from pGADT7-Rec-HeLa cDNA library transformed to AH109 yeast by mating method. By the selection procedures, a total of 939 colonies of the SD/-AHLT culture, 348 colonies of the $X-\alpha-gal$ positive and PCR, 157 colonies of the $X-\beta-gal$ assay were chosen for sequencing the cDNA and finally 90 colonies containing ORF were selected to analyze the interactions. GRA proteins interacted with a variety of host cell proteins such as enzymes, structural and functional proteins of organellar proteins of broad spectrum. Several specific bindings of each GRA protein to host proteins were discussed presumptively the role of GRA proteins after secreting into the parasitophorous vacuoles (PV) and the PV membrane in the parasitism of this parasite.

클라우드 시스템에서 동적 임계치와 호스트 평판도를 기반으로 한 성능 및 에너지 중심 자원 프로비저닝 (Performance and Energy Oriented Resource Provisioning in Cloud Systems Based on Dynamic Thresholds and Host Reputation)

  • 프랭크 엘리호데;이재완
    • 인터넷정보학회논문지
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    • 제14권5호
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    • pp.39-48
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    • 2013
  • 정의된 SLA의 QoS를 지키기 위해서, 클라우드 시스템은 동적인 사용 패턴에서 발생하는 변화무쌍한 작업 부하를 처리해야 한다. 서비스 관점이외에도 에너지 소비를 최소화 하는 것이 또한 새로운 관심사이다. 이는 클라우드 데이타 센터에서 가상화된 자원을 할당할 때 클라우드 제공자들은 에너지와 성능의 상관관계를 고려해야 한다. 본 논문에서는 호스트 컴퓨터의 작업부하 수준을 탐지하기 위해 동적 임계치를 기반으로 한 자원 프로비저닝 방안을 제시한다. VM선정 정책은 이주할 VM을 선택하기 위해 활용 데이터를 사용하며, VM 할당 정책은 서비스 평판도에 따라 VM들을 호스트에 지정한다. 시뮬레이션을 통해 연구결과를 평가하였으며, 시뮬레이션 결과 이주를 지원하지 않는 비 전력 방법뿐만 아니라 동적 임계치, 임의 선정 정책보다 성능이 우수함을 보였다.

효율적인 인터넷 범죄수사를 위한 범행호스트 탐지 및 범죄행위 입증기술 (Network Forensic Evidence Generation and Verification Scheme)

  • 김형석;김은진;김휘강
    • 정보보호학회논문지
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    • 제22권4호
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    • pp.719-731
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    • 2012
  • 인터넷범죄를 수사함에 있어 가장 중요한 점은 범행호스트의 범행을 입증하는 것이다. 그러나 범죄자들은 범행부인을 위해 범행호스트의 IP주소를 변경하거나 패킷의 출발지 IP주소를 조작한다. 또한 악의적인 어플리케이션을 이용하여 범행기록을 남기지 않는다. 본 논문은 인터넷범죄수사의 한계를 극복하기 위한 Network Forensic Evidence Generation and Verification Scheme을 제안한다. 이 기술은 인터넷범죄수사를 위해 패킷의 생성위치와 전송과정에 주소필드가 조작되지 않았음을 보장하는 증거를 생성하여, 범행기록이 부재하여도 패킷을 통해 입증한다. 그리고 증거생성에 의한 라우터의 성능저하를 최소화하기 위해 Timestamp SecretKey Distribution Scheme과 Flow-Based Selection Scheme을 추가 제안한다. 마지막으로 제안한 기술들을 활용하기 위한 시스템을 구현하고 패킷전송률을 실험한다.

Unsupervised learning with hierarchical feature selection for DDoS mitigation within the ISP domain

  • Ko, Ili;Chambers, Desmond;Barrett, Enda
    • ETRI Journal
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    • 제41권5호
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    • pp.574-584
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    • 2019
  • A new Mirai variant found recently was equipped with a dynamic update ability, which increases the level of difficulty for DDoS mitigation. Continuous development of 5G technology and an increasing number of Internet of Things (IoT) devices connected to the network pose serious threats to cyber security. Therefore, researchers have tried to develop better DDoS mitigation systems. However, the majority of the existing models provide centralized solutions either by deploying the system with additional servers at the host site, on the cloud, or at third party locations, which may cause latency. Since Internet service providers (ISP) are links between the internet and users, deploying the defense system within the ISP domain is the panacea for delivering an efficient solution. To cope with the dynamic nature of the new DDoS attacks, we utilized an unsupervised artificial neural network to develop a hierarchical two-layered self-organizing map equipped with a twofold feature selection for DDoS mitigation within the ISP domain.

Insights into factors affecting synonymous codon usage in apple mosaic virus and its host adaptability

  • Pourrahim, R.;Farzadfar, Sh.
    • Journal of Plant Biotechnology
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    • 제49권1호
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    • pp.46-60
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    • 2022
  • The genetic variability and population structure of apple mosaic virus (ApMV) have been studied; however, synonymous codon usage patterns influencing the survival rates and fitness of ApMV have not been reported. Based on phylogenetic analyses of 52 ApMV coat protein (CP) sequences obtained from apple, pear, and hazelnut, ApMV isolates were clustered into two groups. High molecular diversity in GII may indicate their recent expansion. A constant and conserved genomic composition of the CP sequences was inferred from the low codon usage bias. Nucleotide composition and relative synonymous codon usage (RSCU) analysis indicated that the ApMV CP gene is AU-rich, but G- and U-ending codons are favored while coding amino acids. This unequal use of nucleotides together with parity rule 2 and the effective number of codon (ENC) plots indicate that mutation pressure together with natural selection drives codon usage patterns in the CP gene. However, in this combination, selection pressure plays a more crucial role. Based on principal component analysis plots, ApMV seems to have originated from apple trees in Europe. However, according to the relative codon deoptimization index and codon adaptation index (CAI) analyses, ApMV exhibited the greatest fitness to hazelnut. As inferred from the results of the similarity index analysis, hazelnut has a major role in shaping ApMV RSCU patterns, which is consistent with the CAI analysis results. This study contributes to the understanding of plant virus evolution, reveals novel information about ApMV evolutionary fitness, and helps find better ApMV management strategies.

Tolerance: An Ideal Co-Survival Crop Breeding System of Pest and Host in Nature with Reference to Maize

  • Kim, Soon-Kwon
    • 한국작물학회지
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    • 제45권1호
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    • pp.59-70
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    • 2000
  • In nature, plant diseases, insects and parasites (hereafter called as "pest") must be co-survived. The most common expression of co-survival of a host crop to the pest can be tolerance. With tolerance, chemical uses can be minimized and it protects environment and sustains host productivity and the minimum pest survival. Tolerance can be applicable in all living organisms including crop plants, lifestocks and even human beings. Tolerant system controls pest about 90 to 95% (this pest control system often be called as horizontal or partial resistance), while the use of chemicals or selection of high resistance controls pest 100% (the most expression of this control system is vertical resistance or true resistance). Controlling or eliminating the pests by either chemicals or vertical resistance create new problems in nature and destroy the co-survial balance of pest and host. Controlling pests through tolerance can only permit co-survive of pests and hosts. Tolerance is durable and environmentally-friend. Crop cultivars based on tolerance system are different from those developed by genetically modified organism (GMO) system. The former stabilizes genetic balance of a pest and a host crop in nature while the latter destabilizes the genetic balance due to 100% control. For three decades, the author has implemented the tolerance system in breeding maize cultivars against various pests in both tropical and temperate environments. Parasitic weed Striga species known as the greatest biological problem in agriculture has even been controlled through this system. The final effect of the tolerance can be an integrated genetic pest management (IGPM) without any chemical uses and it makes co-survival of pests in nature.in nature.

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The Influence of South Korea's OFDI under the Effects of Multinational Enterprises' Investment Motivations and Host Country Institutions

  • Jie Gao;Jianlin Li;Ke Yuan;Wanli Liu
    • Journal of Korea Trade
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    • 제26권5호
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    • pp.1-22
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    • 2022
  • Purpose - This study aims to analyze the influence of South Korea's outward foreign direct investment (OFDI) under the effect of both multinational enterprises' (MNEs) investment motivation and host country institutions. Some suggestions are put forward with regard to South Korean MNEs participating in and integrating into the fierce and changeable world of international market competition. Design/methodology - The basic hypotheses are that MNEs' investment motivations and the host country's superior institutions both boost South Korea's OFDI in those host countries. South Korea's OFDI is divided into investment choice stage and investment scale stage. A Heckman two-stage selection model is established for empirical analysis, using the panel data of South Korea's OFDI and related variables, from 2002 to 2019. Findings - (1) The influence on the investment scale of South Korea's OFDI is more regular and noteworthy than the influence on investment choice. (2) In the investment scale stage, there are obvious motivations to seek markets, labor force and superior technology, but not natural resources. (3) In the investment scale stage, the South Korea's OFDI is more obviously attracted by the host country's superior political institutions, economic institutions and legal institutions, but not cultural institutions. Originality/value - The choices of variables and uses of model expand the theoretical basis and empirical method of OFDI research. The results of the empirical study also provide some reference for the transnational investment of South Korean MNEs and the investment policy formulation of the South Korean government.

Genetic and Environmental Deterrents to Breeding for Disease Resistance in Dairy Cattle

  • Lin, C.Y.;Aggrey, S.E.
    • Asian-Australasian Journal of Animal Sciences
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    • 제16권9호
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    • pp.1247-1253
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    • 2003
  • Selection for increased milk production in dairy cows has often resulted in a higher incidence of disease and thus incurred a greater health costs. Considerable interests have been shown in breeding dairy cattle for disease resistance in recent years. This paper discusses the limitations of breeding dairy cattle for genetic resistance in six parts: 1) complexity of disease resistance, 2) difficulty in estimating genetic parameters for planning breeding programs against disease, 3) undesirable relationship between production traits and disease, 4) disease as affected by recessive genes, 5) new mutation of the pathogens, and 6) variable environmental factors. The hidden problems of estimating genetic and phenotypic parameters involving disease incidence were examined in terms of categorical nature, non-independence, heterogeneity of error variance, non-randomness, and automatic relationship between disease and production traits. In light of these limitations, the prospect for increasing genetic resistance by conventional breeding methods would not be so bright as we like. Since the phenomenon of disease is the result of a joint interaction among host genotype, pathogen genotype and environment, it becomes essential to adopt an integrated approach of increasing genetic resistance of the host animals, manipulating the pathogen genotypes, developing effective vaccines and drugs, and improving the environmental conditions. The advances in DNA-based technology show considerable promise in directly manipulating host and pathogen genomes for genetic resistance and producing vaccines and drugs for prevention and medication to promote the wellbeing of the animals.