• IMMUNE NETWORK
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• v.10 no.2
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• pp.46-54
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• 2010

Background: Graft-versus-host disease (GVHD) is initiated when alloreactive donor T cells are primed by host APCs to undergo clonal expansion and maturation. Since there is a controversy regarding the role of nonhematopoietic cells in GVHD, we wanted to investigate the influence of MHC disparity on nonhematopoietic cells on the pathogenesis of GVHD in the MHC-haplomismatched C57BL/6 ($H-2^b$) or DBA/2 $(H-2^b){\rightarrow}$unirradiated ($C57BL/6{\times}DBA/2$) $F_1(BDF_1;\;H-2^{b/d})$ murine model of acute GVHD (aGVHD) or chronic GVHD (cGVHD). Methods: We generated ($BDF_1{\rightarrow}C57BL/6$), ($BDF_1{\rightarrow}DBA/2$), and ($BDF1{\rightarrow}BDF_1$) chimeras and examined GVHD-related parameters and donor cell engraftment in those chimeras. Results: Using this experimental system, we found that 1) severe aGVHD across MHC Ag barrier depends on the expression of nonhematopoietically rather than hematopoietically derived alloAgs for maximal GVHD manifestations; 2) host APCs were sufficient to break B cell tolerance to self molecules in cGVHD, whereas host APCs were insufficient to induce autoimmunity in aGVHD; 3) donor cell engraftment was greatly enhanced in the host with MHC-matched nonhematopoietic cells. Conclusion: Taken together, our results provide an insight into how MHC disparity on GVHD target organs contribute to the pathogenesis of GVHD.

• Applied Microscopy
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• v.17 no.1
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• pp.161-168
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• 1987

The elongated filamentous haustorial cells, hyphae, of Cuscuta australis R. Brown penetrated into the vascular tissues of the host plant Trifolium repens L. were studied by the light and electron microscopes. The hyphae reached the host xylem were invaded into the host vessels and then they grew within the host vessels. Finally these hyphae were differentiated into the water conducting elements, xylary hyphae, by thickening of the secondary walls. The hyphae reached the host phloem were branched at the apical regions. These hyphae possessed thin-layered cytoplasm involving the typical features of sieve elements such as the parallel arrays of smooth endoplasmic reticulum, plastids with the clusters of fine starch granules, and mitochondria with the dilated cristae. It was indicated that these hyphae were differentiated into the nutrients conducting elements, phloic hyphae. The structures described were compared with those of other parasitic plants and were discussed in view of the translocation of materials from host to parasite.

• The Bulletin of The Korean Astronomical Society
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• v.42 no.1
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• pp.53.2-53.2
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• 2017

The origin of the well-known correlation between Hubble residual of Type Ia Supernova (SN Ia) and mass of their host galaxies is yet to be fully understood. In our first paper of our YOnsei Evolutionary Supernovae Evolutionary Investigation (YONSEI) project, we found a significant (${\sim}3.9{\sigma}$) correlation between host galaxy mass (velocity dispersion) and population age from high S/N host spectra observed using LCO 2.5 m telescope. Since there is no correlation with metallicity, our result suggests that stellar population age is mainly responsible for the relation between host mass and HR. In order to explore this more directly, we have subsequently observed more sample of nearby early-type host galaxies using MMT 6.5 m telescope. In this poster presentation, we will report our progress in this project and show the preliminary results from our MMT observations.

• Korea Trade Review
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• v.46 no.2
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• pp.177-191
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• 2021

Based on the existing OFDI (outward foreign direct investment) literature, this study endeavored to verify how the corruption of host countries affects the partner strategy of EMNEs (emerging multinational enterprises) when EMNEs enter global markets through joint ventures. Following the existing literature, this study classified corruption and partner strategies into two categories, respectively. First, the corruption of host country was divided into grand corruption and petty corruption. Second, EMNEs' joint venture partner strategy was divided into home country partner joint venture and host country (i.e., local) partner joint venture. Our hypothesis suggested that the greater the host country's grand corruption, the more EMNEs would choose the host country partner, while the strong petty corruption leads to the preference of home country partner in host country. The hypotheses were verified with a sample of 890 foreign direct investment cases of Chinese multinational companies from 2005 to 2015. As a result of the study, regardless of the degree of corruption, it was found that they prefer joint ventures with home country partners when EMNEs enter the global market through joint ventures.

• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.817-819
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• 2009

We have developed highly efficient blue phosphorescent organic light-emitting devices (PHOLEDs) with simplified architectures using new host materials. The Blue PHOLED with new host:FIrpic emitting layer exhibits a maximum luminance efficiency of 34 cd/A and a low operating voltage 5 V at a high luminance of 1212 cd/$m^2$.

• Genomics & Informatics
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• v.3 no.3
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• pp.63-67
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• 2005

Adaptive responses to diverse microbial pathogens might be limited in relatively few types. Host cell responses to pathogens are believed to be patterned or stereotyped along with species or class. We tried to compose the host response to Mycoplasma in terms of cellular gene expression. Although gene expression profile of two host HeLa and 293 cells were quite different each other, 30 genes were differentially expressed by mycoplasma infection in both of HeLa and 293 cells. Six of them (PR48, MADH4, MKPX, CRK, RBM7, NEK3) were related to cell cycle or proliferation. Another category of genes like IL1 HY1, KLRF1, TNFSF14, GBP1 were host defense to elicit immune responses. With this set of genes, we establish the prediction model for mycoplasma contamination.

• Asia-Pacific Journal of Business
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• v.15 no.2
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• pp.237-256
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• 2024

Purpose - The purpose of this study was to analyze the interrelationship between the characteristics of TikTok live commerce: host expertise, host reliability, sales marketing strategy, product price, logistics speed, refund convenience), purchase intention, and continuous purchase intention. Design/methodology/approach - This study collected 470 questionnaires collected from the survey for consumers using TikTok live commerce in China and conducted an empirical analysis using SPSS 24.0 statistical packages for 423 valid questionnaires (90%) excluding unfaithful responses. Findings - First, it was confirmed that the characteristics of TikTok Live (host expertise, host reliability, sales marketing strategy, product price, logistics speed, and refund convenience) had a positive effect on consumers' purchase intention. Second, it was confirmed that the higher the consumer's purchase intention, the higher the continuous purchase intention. Third, it was also confirmed that the characteristics of TikTok Live (host expertise, host reliability, sales marketing strategy, product price, logistics speed, and refund convenience) had a positive effect on consumers' continuous purchase intention. Research implications or Originality - Through the research results of this paper, product prices have the greatest influence on consumers' purchase intentions, followed by sales marketing strategies and host expertise. Therefore, this study aims to present implications for product prices, sales marketing strategies, and host expertise in TikTok live commerce based on empirical analysis and analysis of previous studies.

• Research in Plant Disease
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• v.11 no.2
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• pp.98-105
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• 2005

All viruses have few genes relative to their hosts. Viruses, thus, utilize many host factors for efficient viral replication in host cell. Virus-host interactions are crucial determinations of host range, replication, and pathology. Host factors participate in most steps of positive-strand RNA virus infection, including entry, viral gene expression, virion assembly, and release. Recent data show that host factors play important roles in assembling the viral RNA replication complex, selecting and recruiting viral RNA replication templates, activating the viral complex for RNA synthesis, and the other steps. These virus-host interactions may contribute to the host specificity and/or pathology. Positive-strand RNA viruses encompass over two-thirds of all virus genera and include numerous pathogens. This review focuses on the importance of host factors involved in positive strand plant RNA virus genome replication.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.439-442
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• 2008

A mixed host structure of TCTA and TPBI was used in orange emitting layer and host composition was critical to device performances of PHWOLEDs. PHWOLEDs with TPBI host in orange emitting layer showed high quantum efficiency of 10.3 % at $1000\;cd/m^2$ with little change of CIE coordinates of (0.32, 0.34) from $100\;cd/m^2$ to $10,000\;cd/m^2$.

• The Plant Pathology Journal
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• v.37 no.5
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• pp.494-501
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• 2021

Pseudomonas cichorii secretes effectors that suppress defense mechanisms in host plants. However, the function of these effectors, including avirulence protein E1 (AvrE1), in the pathogenicity of P. cichorii, remains unexplored. In this study, to investigate the function of avrE1 in P. cichorii JBC1 (PcJBC1), we created an avrE1-deficient mutant (JBC1^ΔavrE1) using CRISPR/Cas9. The disease severity caused by JBC1^ΔavrE1 in tomato plants significantly decreased by reducing water soaking during early infection stage, as evidenced by the electrolyte leakage in infected leaves. The disease symptoms caused by JBC1^ΔavrE1 in the cabbage midrib were light-brown spots compared to the dark-colored ones caused by PcJBC1, which indicates the role of AvrE1 in cell lysis. The avrE1-deficient mutant failed to elicit cell death in non-host tobacco plants. Disease severity and cell death caused by JBC1^ΔavrE1 in host and non-host plants were restored through heterologous complementation with avrE1 from Pseudomonas syringae pv. tomato DC3000 (PstDC3000). Overall, our results indicate that avrE1 contributes to cell death during early infection, which consequently increases disease development in host plants. The roles of PcJBC1 AvrE1 in host cells remain to be elucidated.