• 대한치과마취과학회지
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• 제5권1호
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• pp.15-21
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• 2005

Autism is characterized with an abnormality of reciprocal social relatedness and of communication development. Also, autistic children show repetitive and stereotypical behavior pattern and deficiency of endurance against change. Dental problems related to autism are self-injury and trauma from accidents. Sometimes self-injury is due to discomfort resulting from restoration and local anesthesia. Also, gingivitis and multiple caries are common because of poor oral hygiene. Autistic children are anxious about visual and auditory stimuli because they don't understand the dental procedure. If the face of any changes in their daily life, their behavior becomes uncontrollable. In a setting such as the outpatient office, an autistic child's uncontrollable behavior makes it difficult to carry out proper treatment. If they need treatment under general anesthesia, it is very difficult to manage them in a ward as they are severly anxious about being admitted to a hospital. Therefore it is necessary to treat these children according to a specific management program under general anesthesia in an outpatient office. This case study reports of a 14 year old autistic teenager who although became uncontrollable because of the pain from multiple caries and from anxiety of the dental treatment eventually received treatment under general anesthesia and under conscious sedation in an outpatient office.

• Asian Pacific Journal of Cancer Prevention
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• 제17권3호
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• pp.1015-1018
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• 2016

Background: Overexpression or amplification of human epidermal growth factor receptor-2 (HER2) is associated with grade of malignancy and a poor prognosis in breast cancer (BC). The aim of this study was to evaluate of value of HER2 as a prognostic marker, and to analyze associations with common histopathological parameters in BC cases. Materials and Methods: Between of 2007 to 2014, 260 patients with BC referred to Oncology Clinic provided cancer tissue samples which underwent immunohistochemistry (IHC) for markers. ER and PR positivity was defined as ${\geq}10%$ positive tumor cells with nuclear staining. HER2-positive was defined as either HER2 gene amplification by fluorescent in situ hybridization (FISH) or scored as 3+ by IHC. For HER2 (2+), FISH was performed to determine HER2 positivity. Results: The mean age at diagnosis for the patients with HER2-negative was significantly higher than in HER2-positive cases. Also, there were significant correlations between histological grade, nuclear grade, lymph node metastasis, tumor size, ER status, PR status, p53 overexpression and Ki-67 index with HER2 expression. HER2-negative lesions were of higher grade and more likely to be ER-negative, PR-negative, p53-positive, lymph node metastasis, with a tumor size<2cm and also $Ki-67{\geq}20%$ as compared to the HER2-positive group. Conclusions: Contrary to the results of other studies, HER2-positive tumors in our study had a lower Ki-67 index and were p53-positive. Also, Ki-67 proliferation index ${\geq}20%$ in more studies was associated with p53-positive.Therefore, tumors which are HER2-positive and have a Ki-$67{\geq}20%$ had a more aggressive behavior compared to HER2-positive and Ki-67<20% lesions.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7517-7522
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• 2015

Onion (Allium cepa) consumption has been remarked in folk medicine which has not been noted to be administered so far as an adjunct to conventional doxorubicin-based chemotherapy in breast cancer patients. To our knowledge, this is the first study aimed to investigate the effects of consuming fresh yellow onions on hepatic enzymes and cancer specific antigens compared with a low-onion containing diet among breast cancer (BC) participants treated with doxorubicin. This parallel design randomized controlled clinical trial was conducted on 56 BC patients whose malignancy was confirmed with histopathological examination. Subjects were assigned in a stratified-random allocation into either group received body mass index dependent 100-160 g/d of onion as high onion group (HO; n=28) or 30-40 g/d small onion in low onion group (LO; n=28) for eight weeks intervention. Participants, care givers and laboratory assessor were blinded to the assignments (IRCT registry no: IRCT2012103111335N1). The compliance of participants in the analysis was appropriate (87.9%). Comparing changes throughout pre- and post-dose treatments indicated significant controls on carcinoembryonic antigen, cancer antigen-125 and alkaline phosphatase levels in the HO group (P<0.05). Our findings for the first time showed that regular onion administration could be effective for hepatic enzyme conveying adjuvant chemotherapy relevant toxicity and reducing the tumor markers in BC during doxorubicin-based chemotherapy.

• 대한임상독성학회지
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• 제8권1호
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• pp.37-42
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• 2010

Purpose: The purpose of this study was to determine the optimal length of time to observe patients with contrast media anaphylaxis in the Emergency Department. Methods: This study included the patients of all age groups who presented with anaphylaxis due to contrast media to the ED of Pusan National University Hospital from January 2006 to August 2009. The medical records were retrospectively reviewed. We analyzed the 100 patients who met the inclusion criteria. Their median age was 55 (46-62), and 38 out of the 100 patients (38%) were male. Results: The most common symptom of patients was urticaria. Corticosteroid and H1 antihistamine were given to most of the patients in the ED. All were discharged after observation in the ED and none were admitted to the ward. The average time from injection of the contrast media to the onset of symptom was 31 minutes (24-39) and the average time to symptom recovery was 127 minutes (89-188). The mean observation time in the ED was 93 minutes (59-153). Biphasic reactions were reported in only one case (1/100, 1%). Conclusion: These results suggest that patients who present with an anaphylactic reaction after radiologic studies that use intravenous contrast media can be safely discharged early from the ED because the symptom recovery time is not long and a biphasic reaction is rare.

• 여성건강간호학회지
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• 제3권2호
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• pp.180-191
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• 1997

When women are removed with their matrix which is a emotionally significant organ of symbol in psychologically adapting themselves to mother and woman, that is threatened and injured with woman role decisively. The nursing for women with hysterectomy is limited to medical treatment and the nursing related to troubles in psychology, emotion they experience in general situation due to operations is hardly realized. New basis for nursing can be realized when we both have relation with lived human experience related th health and become to be a part of it. We need to catch their experience due to the loss of matrix to understand women with hysterectomy. The subjects of the study were nine patients who were admitted to a gynecological ward of a hospital in Seoul, suffering from vaginal bleeding, back pain, abdominal pain and so on and diagnosing as non-cancer. The data were collected from April to May 1997 by listening to the subjects' expression of their experience and by participant observation of the subjects' reactions. A tape-recorder was used under the permission of the subjects, to prevent the loss of spoken information. The result of the study was as follows : The data on burden content from the interview were categorized as psych-emotional, physical, personal interaction, financial burden and maternal role burden. The factors which have influence on the burden of the subjects are an offer of information, support system, age, occupation, economic situation, family history, character, season, the existence of ovary and religion. In conclusion, since we ascertained that the nursing in the process of recovery decide the quality of life, though women with hysterectomy undergo various burden experience and adapt to it in the end, it is necessary to give them enough information and educate husband, having on important effect on the burden experience, to be a good supporter. And technically skilled nurses of consultant are thought to be able to contrive better qualitative life of women with hysterectomy as an important bridge between the subjects and their required information, since the nurses have their well-formed position of relationship of confidence through continuous contact with patients and their family.

• Clinical and Experimental Pediatrics
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• 제56권9호
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• pp.383-388
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• 2013

Purpose: Viral etiology is common in cases of children with acute diarrhea, and antibiotic therapy is usually not required. Therefore, it is important to determine the distribution of common viruses among children hospitalized with acute diarrhea. Methods: We included 186 children who suffered from acute diarrhea and were hospitalized at the Wonkwang University Hospital Pediatric ward from December 1, 2010 to June 30, 2011 in this study. Stool samples were collected and multiplex reverse transcriptase polymerase chain reaction (multiplex RT-PCR) was used to simultaneously determine the viral etiology such as rotavirus, norovirus, astrovirus, or adenovirus. Results: Causative viruses were detected in 72 of the 186 cases (38.7%). The mean age of the virus-positive cases was 1 year and 9 months (range, 1 month to 11 years). Rotavirus was detected in 50/186 (26.9%); norovirus, in 18/186 (9.7%); and astrovirus, in 3/186 cases (1.6%). Adenovirus was not detected in any of the cases. Proportions of norovirus genogroups I and II were 21.1% and 78.9%, respectively. Four of the 51 rotavirus-positive cases (7.8%) had received rotavirus vaccination at least once. The mean duration of diarrhea was 2.8 days (range, 1 to 10 days) and vomiting occurred in 39 of the 72 cases (54.2%). Conclusion: Viral etiology was confirmed in about one-third of the children with acute diarrhea, and the most common viral agent was rotavirus, followed by norovirus.

• 대한간호학회지
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• 제16권3호
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• pp.97-107
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• 1986

This study was about nurse's helping behaviors and the purpose of the study was to find out the nurse's helping behaviors, to identify the nurse's helping behavior level by the nurses personal back-ground and to find out the relationship between the nurse's helping behavior and patient's self-exploration. The subjects, consisting of 192 adults in-patients who had less acute physical problem and 192 registered nurses working on these ward in 3 hospitals in Seoul and 1 hospital in Kang Won province of Korea. The data were collected from Jan. to rob. 1986 through the descriptive responds and self-reported questionaires. The instruments used for this study were Carkhuff's index of communication. Henderson's Irritating Listening Behavior, revised by the Kim(1984) and patient problem understanding scale, patients trust scale on nurse, developed by the Kim(1984). Analysis of the Data was done by use of mean, t-test, F-test and Pearson correlation coefficients. The results of study are summerized as follows; 1. Mean of nurse's helping behavior was 1.84 out of 4. These point were less than 3.0 which means the minimum points as the facilitative helper. 3. There was no significant differences of nurses helping behaviors to the nurse's personal back-ground (p<.05). 3. There were positive rotation between the nurse's helping behaviors and patient's self-exploration behavior (P<0001). In conclusion, 1 may can give some suggestion, according to the study results: 1. The systematic study about nurse's helping behavior is need all over the Korea. 2. Educational program for the facilitative relationship between nurses and patient must be developed, 3. Further detailed analysis methods are need on the independent variables of patient's self-explorations behavior.

• Pediatric Infection and Vaccine
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• 제25권2호
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• pp.101-106
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• 2018

6세 남아가 인플루엔자 A 바이러스 감염 이후 급성 호흡부전 상태에서 내원하였다. 기관 삽관 이후 인공 호흡 및 산화 질소공급에도 호흡성 산증 및 저산소증의 호전이 없어 내원 9시간 이후 체외막 산소 공급을 이용하여 호흡 보조를 시행하였다. 내원 12시간 이후 기관지경을 이용하여 우측 중간 기관지부터 상엽 구멍을 막고 있는 단단한 점액 마개를 제거하였다. 이후 환자는 신경계와 호흡기계 후유증 없이 퇴원하였다. 저자들은 플라스틱 기관지염으로 인한 급성 호흡 부전 상태의 환자에서 신속한 체외막 산소 공급 및 기관지경술의 처치를 시행함으로써 후유증 없이 치료한 사례를 보고한다.

• 한국산학기술학회논문지
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• 제16권4호
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• pp.2726-2736
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• 2015

본 연구는 한방병원 이용 환자들의 의료서비스 만족도와 재이용의사 결정요인을 파악하여 향후 한방병원 경쟁력 강화전략의 기초자료를 제공하고자 시행되었다. 의사, 간호사, 직원 등의 인적 서비스 요소와 진료과정, 진료비 청구, 병원내 환경, 병원내 시설, 입원생활 만족도 등의 인적 외 서비스 요소 등 총 8개의 요인별 만족도가 전반적 만족도와 재이용 의사에 직접적인 영향을 미치며 한편으로는 각 요인들이 전반적 만족도를 통하여 재이용의사에 간접적인 영향도 미친다는 하나의 경로모형을 분석의 기본틀로 설정하였다. 충남지역 한방 병원 3개소의 외래 및 입원환자 578명을 대상으로 2014년 10월부터 12월까지 구조화된 설문지로 자료를 조사하였다. 분석결과 유의한 변수는 외래의 경우 전반적 만족도, 의사의 진료, 진료과정에 대한 만족도이었으며, 입원의 경우에는 전반적 만족도, 병원시설, 진료비, 병동생활에 대한 만족도가 중요한 변수로 분석되었다.

• 한국간호교육학회지
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• 제17권1호
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• pp.100-109
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• 2011

Purpose: This study was conducted to investigate how a program using video-audio media will affect the knowledge level and compliance of the sick role of patients admitted for coronary angiography. Method: A non-equivalent control group non-synchronized design was used. Subjects were selected from patients admitted to the internal ward of a hospital in B city for coronary angiography between July 1 and September 31, 2010. Twenty subjects were assigned to the control and experimental group, respectively. Video-audio media developed by the authors was used as the experimental tool. The effects of the program were analyzed using a knowledge assessment tool and questionnaire for compliance of the sick role. The SPSS/WIN 14.0 program was used for data analysis. Result: The first hypothesis that the "experimental group receiving the program using video-audio media will report a higher level of knowledge compared to the control group" was supported. The second hypothesis that the "experimental group that received the program using video-audio media will report a higher level of compliance of sick role" was supported. Conclusion: The program using video-audio media was effective in enhancing patients' knowledge about the disease and compliance of the sick role. Thus, it can be an effective nursing intervention for patients with coronary artery disease.