• Archives of Plastic Surgery
• /
• v.48 no.3
• /
• pp.261-268
• /
• 2021

Background Various methods have been described to close large meningomyelocele defects, but no technique has been proven superior to others. This study presents cases of meningomyelocele defect closure with a keystone-design perforator island flap. Methods A retrospective study was performed on 14 patients with meningomyelocele defects closed using various types of keystone flaps. Results The median age of the patients at surgery was 10.5 days (range, 1-369 days) and the average defect size was 22.5 cm² (range, 7.1-55.0 cm²). The average operative time for defect closure was 89.6 minutes (range, 45-120 minutes). Type IV bilateral keystone flaps were used for four defects, type IV unilateral flaps for six defects, type IIA flaps for two defects, and type III flaps for two defects. Conclusions All the defects healed completely with no major complications. The keystone-design perforator island flap is a reliable, easy, and fast technique to close large meningomyelocele defects.

• Medical Lasers
• /
• v.10 no.4
• /
• pp.229-237
• /
• 2021

Background and Objectives To assess the effectiveness of overnight orthokeratology (OK) in myopia using a new contact lens design over a one-month wearing period. Materials and Methods Participants were required to have myopia between -3.00 and -7.50D and astigmatism ≤ 2.00 D to participate in the study. The participants underwent OK with the White OK lens^® (Interojo, Pyungtek, Korea), which has a 6-curve lens design. Participants were assessed at weeks 1, 2, and 4 using slit-lamp bio-microscopy, and tested for refraction, uncorrected distance visual acuity, and corneal topography. Success was defined as achieving a Logarithm of the Minimum Angle of Resolution (logMAR) ≤ 0.1. Results A total of 46 eligible subjects with a mean age of 23.11 ± 7.89 years were recruited. Baseline logMAR was 1.18 ± 0.30 and a consistent decrease in logMAR was observed from week 1 to week 4. The success rate was 95.35% at week 4. The mean sphere significantly decreased from a mean pre-fitting value of -4.58 ± 1.28 D to a mean value of -0.65 ± 0.69 D at week 4 (p < 0.0001). Statistically significant corneal flattening was detected during keratometry at week 4. Conclusion Overnight OK with the White OK lens is effective for the correction of moderate and high myopia with astigmatism over a one-month wearing period.

• Steel and Composite Structures
• /
• v.47 no.4
• /
• pp.467-488
• /
• 2023

Seismic retrofit of an existing steel-reinforced concrete hospital building that features innovative use of a continuous energy-dissipative steel column (CEDC) system is presented in this paper. The special system has been adopted to provide an efficient solution taking into account the difficulties of applying traditional intervention techniques to minimize the impact on architectural functionality and avoid the loss of building function and evacuation during the retrofit implementation. The lateral stiffness and strength of the CEDC system were defined based on the geometric and mechanical properties of the steel strip dampers. The hysteretic behavior under cyclic loadings was defined using a simplified numerical model. Its effectiveness was validated by comparing the results of full-scale experimental data available from the literature. All the main design considerations of the retrofitting plan are described in detail. The effectiveness of the proposed retrofitting system was demonstrated by nonlinear time-history analyses under different sets of earthquake-strong ground motions. The analysis results show that the CEDC system is effective in controlling the deformation pattern and significantly reducing damage to the existing structure during major earthquakes.

• Proceedings of the Korean Institute of Building Construction Conference
• /
• 2021.05a
• /
• pp.166-167
• /
• 2021

The elderly population in Korea is constantly increasing. As the number of Long-Term Care hospitals increases, many fires have occurred in related facilities. In this facilities, due to the characteristics of the occupants, self-evacuation is difficult, resulting in a number of casualties. It is necessary to Life safety design that reflects the characteristics of the occupants of domestic long-term hospitals. The study attempted to suggest improvements to the standards of evacuation behavior model for occupants of domestic and overseas long-term care hospitals. As a result of the study, patients living in long-term hospitals have a problem that is difficult to evacuate on their own. It is judged that there is a need to present an evacuation behavior model database by setting evacuation priorities and evacuation plans. In addition, it is necessary to more the design factors that affect the evacuation model as well as the characteristics of the occupants of the long-term care hospital.

• Korean Journal of Occupational Health Nursing
• /
• v.21 no.2
• /
• pp.87-97
• /
• 2012

Purpose: This study was to examine the relationship between recovery experience and the burnout among hospital nurses. Methods: A cross-sectional survey design was used. The participants were 281 nurses working at three general hospitals located in Seoul and Gyeonggi Province. The data were collected by convenience sampling using self-reported questionnaires that consisted of general characteristics, burnout, recovery experiences, self-efficacy, social support, job demand and organizational system. The data were analyzed with descriptive statistics, t-test, ANOVA, correlation, and stepwise multiple regression. Results: Stepwise multiple regression showed that organizational system had the greatest impact on hospital nurses' burnout, followed by job demand, self efficacy, position and recovery experience. Conclusion: Recovery experience is found to be a new factor that influences the burnout among hospital nurses. Therefore, further research is needed for confirming that recovery experience influences the burnout of hospital nurses. Also there is a need to develop a program to increase recovery experience from job stress at the organizational level to reduce hospital nurses' burnout.

• Journal of The Korea Institute of Healthcare Architecture
• /
• v.7 no.2
• /
• pp.59-69
• /
• 2001

The purpose of this study is to provide a basic data for architectural planning on the wards and special quality of physical remedy spaces of geriatrics hospital. This research, to analyse dependency degree of inpatients in geriatric hospital, shows relativeness between remedy space and wards, and to show behavior of each patients reaction to there space. Result of interviewed inpatients who were sorted by age, sex, dependency degree, and days in hospital, suitable space programming is to need for physical and mental state. On the bases of survey and analysis, the basic data for planning and design the hospital for the elderly with dementia has been proposed.

• BMB Reports
• /
• v.42 no.10
• /
• pp.636-641
• /
• 2009

The penetrating of monoclonal antibodies (mAbs) into solid tumor may be hampered by their large size. The antibody mimetics, composed of two complementarity-determining regions (CDRs) through a cognate framework region (FR), have been demonstrated to have the capacity to penetrate tumors superior to its parental intact IgG. In this study, we used CDR and FR sequences from the humanized anti-HER2 monoclonal antibody trastuzumab to design four antibody mimetics. Then these antibody mimetics were fused to human IgG Fc to generate mimetics-Fc small antibodies. One of the four mimetics-Fc antibodies binds well to HER2-overexpressing SK-BR3 cells and effectively inhibits the binding of trastuzumab. This mimetics-Fc, denoted as HMTI-Fc, was shown to be effective in mediating antibody-dependent cellular cytotoxicity and exhibit an antiproliferative effect in SK-BR3 cells. To our knowledge, the HMTI-Fc antibody shown here is the smallest fully functional antibody and may have a potential for treatment of cancer.

• Journal of the Korean Institute of Landscape Architecture
• /
• v.41 no.1
• /
• pp.82-92
• /
• 2013

This paper presents a landscape design proposal for the Kyeongsang National University Hospital in Changwon, Kyeongsangnam-do. The site is located at 555 Samjeongja-dong, Seongsan-gu, Changwon, Kyeongsangnam-do, and its area is approximately $79,743.1m^2$. The goal of the design was to create a landscape that helps the patients' recovery and public well-being as well as respects the surrounding environment. In order to achieve this goal, three design subjects were considered: maximizing the healing functions of the landscape, promoting ecologically regenerative landscape, and increasing the aesthetic value of the landscape based on the local context. For the healing aspect, first, therapeutic plants were carefully selected and various healing programs were introduced to the open space area such as the sensory garden, meditative space, the medicinal herb garden, outdoor acupressure treatment facilities, remedial playground etc. In addition, as the importance of patient's privacy is emphasized in research, the space and circulation patterns were divided according to the characteristics of the users. For ecological consideration, the design proposed to preserve and extend the existing ridgeline with pine forest, and recover the natural water system and recycle the water for the landscape management. For the aesthetic experience of the people, in contrast to the surrounding evergreen forest, diverse deciduous and flowering plants were introduced to arouse a sense of the season, and fruit bearing trees for wildlife to create a specific mood of being in nature so that people can listen to the songs of the birds and watch squirrels play etc. In addition, all the spaces and facilities were designed and placed according to universal design principles so that there would be no barrier for the patients to use them. Also, a sustainable management scheme was suggested to maintain the landscape in ecological and economical ways.

• Korean Institute of Interior Design Journal
• /
• v.19 no.3
• /
• pp.234-241
• /
• 2010

Avoiding the unified productivity that was caused by the mechanical and technical development due to Industrial Revolution in the past, modern design is incessantly evolving in search of new motive, namely, diversity. Further, we live in the age when the propensity that serves public interest and purpose and sometimes shows quite individual character should be considered. As a result, the comprehensive and harmonious trend of emotional design is being highlighted more remarkably. Involving the social background that further respects human dignity, this is closely related to diverse issues such as human right which should be guaranteed and pursued for individual. While the tradition and innovation caused by the encounter of machine and art had confrontation and conflict in the past, the direction has changed to incessant evolution and interaction where paradigm of technical progress and development is newly composed and changed in modern times. The meaning of service in medical area is expanding and developing from the simple treatment to the more comprehensive healing. Medical space will evolve to the healing space that attaches importance to emotional aspect of human dimension which further understands and respects human being in the future.

• International Journal of Advanced Culture Technology
• /
• v.9 no.1
• /
• pp.7-15
• /
• 2021

The open space of the healing facility should contribute to the psychological and social healing of the users, provide a social environment for rest, and provide a design factor to support the walking path to move to the destination-connected space. In this paper, I examined the relationship between the environmental elements, spatial devices, and the characteristics of the design factors in the open space for healing facilities. As a research method, based on the analysis of previous studies, a healing facility in modern society was defined, and the relationship between the social support and physical environment factors of the healing facility where open space was considered. Through the consideration of cases, the characteristics of the physical space environment, and the design factors of the open space in the healing facility were categorized. As a result of research, open space in the healing facility is a space to promote a social exchange of users, as a physical form for accommodating psychological and social healing functions, it is necessary to construct the connection of the external space with the internal space.