• The Korean Journal of Pain
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• 제23권2호
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• pp.142-146
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• 2010

Background: Stellate ganglion block (SGB) is known to increase blood flow to the innervations area of the stellate ganglion. Near infrared spectroscopy reflects an increased blood volume and allows continuous, non-invasive, and bedside monitoring of regional cerebral oxygen saturation ($rSO_2$). We investigated the influence of SGB on bilateral cerebral oxygenation using a near infrared spectroscopy. Methods: SGB was performed on 30 patients with 1% lidocaine 10 ml using a paratracheal technique at the C6 level and confirmed by the presence of Horner's syndrome. The blood pressure (BP), heart rate (HR) and rSO2 were measured before SGB and 5, 10, 15 and 20 minutes after SGB. Tympanic temperature of each ear was measured prior to SGB and 20 minutes after SGB. Results: The increments of the $rSO_2$ on the block side from the baseline were statistically significant at 5, 10, 15 and 20 minutes. The $rSO_2$ on the non-block side compared with the baseline, however, decreased at 15 and 20 minutes. The difference between the block and the non-block sides was significant at 15 and 20 minutes. The BP at 10, 15 and 20 minutes was increased and the HR was increased at 10 and 15 minutes. Conclusions: We observed an increment of the $rSO_2$ on the block side from the baseline; however, the $rSO_2$ on the non-block side decreased.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2006년도 춘계학술대회
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• pp.194-194
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• 2006

• The Korean Journal of Pain
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• 제19권2호
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• pp.202-206
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• 2006

Background: Stellate ganglion block (SGB) might be associated with changes in the blood pressure (BP) and heart rate (HR). The heart rate variability (HRV) shows the balance state between sympathetic and parasympathetic activities of the heart. The changes in these parameters of the HRV were studied to evaluate the possible mechanism of SGB in changing the BP. Methods: SGB was performed on 26 patients, using a paratracheal technique at the C6 level, and 8 ml of 1% mepivacaine injected. The success was confirmed by check the Horner's syndrome. The BP, HR and HRV were measured before and 5, 15, 30, 45 and 60 minutes after the SGB. Results: The increases in the BP from the baseline throughout the study period were statistically, but not clinically significant. The HR and LF/HF (low frequency/high frequency) ratio were increased at 5 and 45 min, respectively, after the administration of the SGB. In a comparison of left and right SGB, no significant differences were found in the BP, HR and HRV. A correlation analysis showed that an increased BP was significantly related with the changes in the LF/HF ratio and LF at 15 and 30 minutes, respectively, after the SGB. Dividing the patients into two groups; an increased BP greater and less than 20% of that at the baseline INC and NOT groups, respectively, hoarseness occurred more often in the INC group (P = 0.02). Conclusions: It was concluded that SGB itself does not clinically increase the BP and HR in normal hemodynamic patients. However, the loss of balance between the sympathetic and parasympathetic nerve system, attenuation of the baroreceptor reflex and hoarseness are minor causes of the increase in the BP following SGB; therefore, further studies will be required.

• Journal of Chest Surgery
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• 제27권12호
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• pp.1015-1022
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• 1994

Over the past few years, video-assisted thoracic surgery [VATS] has been used increasingly for intrathoracic pathologic problems as a less invasive operative techniques. Today it is viewed as a sparing and safe alternative to thoracotomy for a wide spectrum of indications. Using video-assisted operative thoracoscopy, we performed consecutive 150 operations on 148 patients during the initial 2 years of our experience from July 1992 with the following indications: pneumothorax [n=53], hyperhidrosis [n=29], mediastinal mass [n=23], pleural disease [n=13], diffuse parenchymal or interstitial lung disease [n=12], benign pulmonary nodule [n=7], metastatic lung mass [n=3], primary lung cancer [n=3], bronchiectasis [n=2], malignant pericardial effusion [n=2], endobronchial tuberculosis [n=1], esophageal achalasia [n=1], and pulmonary parenchymal foreign body [n=1]. There were no death, and overall complicaton rate was 24.0%[n=36]. The most prevalent complication was persistent air leakage [longer than 5 days] in 14 cases [9.3%]. Persistent pleural effusion [longer than 5 days] occurred in 6 cases [4.0%]. Six patients were converted to an open thoracotomy because of inability to control the operative bleeding [n=3], failed adhesiolysis in bronchiectasis [n=2], and radical excision of an lung cancer [n=1]. Pneumothorax recurred in 3 cases[2.0%]. Other complications were Horner`s syndrome, diaphragm tears, temporary phrenic nerve palsy, hoarseness, subsegmental atelectasis, transient respiratory difficulty, and esophageal mucosal tear. The advantages of this minimally traumatizing operative technique lie in improved visualization, decreased pain, shortened hospital stay, and less postoperative morbidity. The indications of VATS has been extended increasingly to intrathoracic pathologies, but its role in the managements of primary lung cancer and esophageal disease remains to be defined.

• The Korean Journal of Pain
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• 제12권1호
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• pp.81-86
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• 1999

Background: Essential hyperhidrosis is a condition with excessive sweating, which may be localized in any parts of the body. Thoracic sympathectomy has been a surgical procedure for the management of hyperhidrosis. Methods: We studied 30 ASA I and II patients suffering from severe hyperhidrosis. Bilateral upper thoracoscopic sympathectomy of $T_{2-4}$ was performed in 30 patients under general anesthesia. Anesthesia was induced with 2.5% thiopental sodium 5 mg/kg and succinylcholine chloride 1 mg/kg and was maintained with enflurane 1~2 Vol% and $N_2O-O_2$ mixture adjusted to maintain $SpO_2$ greater than 96%. During anesthesia, invasive arterial pressure, heart rate, EKG, $SpO_2$ and capnography were monitored. Skin temperature was measured with thermister probes attached to the index finger of each hand. An increase in temperature after cautery confirmed success of the sympathectomy. Results: There were 14 men and 16 women whose ages ranged from 16 to 46 years old (mean age 22.2). Of these patients, 13 patients had complained of palm-sole hyperhidrosis, 9 of palm-sole-axilla hyperhidrosis, 4 of palm-sole-face hyperhidrosis and 4 of palm-sole-axilla-face hyperhidrosis. The provocative factors of excessive sweating were tension and stress from interpersonal relationships. There was positive familial history in 37%. The most common complication was compensatory hyperhidrosis in 23 patients comprising 76%. Other complication included peumothorax (4 patients), hemothorax (1 patient), ipsilateral Horner's syndrome (1 patient) and paresthesia of right arm (1 patient). The degree of satisfaction was graded as good, fair and poor with 15, 12 and 3 patients, respectively. Conclusions: Thoracoscopic sympathectomy with VATS is an efficient, safe and minimally invasive surgical procedure for essential hyperhidrosis.

• Journal of Chest Surgery
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• 제28권7호
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• pp.684-688
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• 1995

Hyperhidrosis, one of the abnormalities in autonomic nervous system, has been treated with dermatologic principles or thoracic sympathectomy via conventional axillary thoracotomy or dorsal spinal approach. But these techniques were rather ineffective or invasive. Recently, VATS is widely applied in thoracic surgical area, and hyperhidrosis is not the exception of these cases.From May 1993 to August 1994, 30 patients with bilateral palmar hyperhidrosis underwent bilateral thoracic [T2, T3 sympathectomy with thoracoscopic surgery at Seoul National University Hospital. There were 20 men and 10 women and the mean age was 23.0 years.Mean operating time was 115 min and there was no thoracotomy conversion. Operative complications were anesthetic overdose in 1, Horner`s syndrome in 1, and small amount of residual pneumothorax in 6. Mean postoperative hospital stay was 2.3 days [range from 1 to 4 days and postoperative analgesics were required in 17 cases with a single dose.Sweating amount was measured in 12 patients, showing significantly decreased amount from 284.5 mg preoperatively to 18.9 mg postoperatively in 5 minutes [p=0.004 . There was no recurrence during mean 6 months follow up. Twenty two patients [73.3 % complained moderate compensatory hyperhidrosis on the trunk.In conclusion, all patients were greatly satisfied with those results including no more palmar sweating, less pain, better cosmetics, short hospital stay. In addition, recent use of sweating amount measurement and intraoperative temperature monitoring could make this technique more accurate, so we easily applied thoracoscopic sympathectomy with minimal risk.

• Journal of Chest Surgery
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• 제31권6호
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• pp.598-603
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• 1998

다한증이란 체온조절에 필요이상의 땀이 어느 특정 부위에서 과도하게 나는 비정상적인 상태이며 손바닥, 발바닥, 머리, 얼굴과 겨드랑이등에 흔하다. 다한증은 젊은 나이에 0.6%에서 1%까지 보고되고 있으며 치료에는 내과적 도포와 이온 영동법에 의한 치료가 있으나 효과가 뚜렷하지 않는 경우에는 흉부교감신경절의 절제가 크게 도움이 된다고 본다. 최근 흉강내시경 기구의 발전으로 2 mm 내시경에 의한 다한증 치료가 가능하게 되어 수술후 통증이나 상처에 대한 걱정없이 수술을 시행할수 있게되었다. 연세대학교 의과대학 영동세브란스병원 훙부외과에서는 1997년 6월부터 1997년 10월까지 117례의 다한증 환자에서 2 mm 흉강경을 이용한 117례의 흉부교감신경절절제술을 시행하였으며 이중 추적가능하였던 94례의 환자에 대한 평균수술시간은 47.50분이었으며 평균입원기간은 1일이었다. 2 mm 흉강경을 이용한 흉부 교감신경절 절제술은 매우 간편하고 상처나 통증에 대한 두려움없이 치료받을수 있는 방법이라 생각되어진다. 수술후 합병증으로는 흉관을 발관하면서 발생한 기흉이 5례있었으며 약간의 호너증후군이 1례 있었다. 수술후 보상성 다한증은 67례(71.2%)에서 나타났으며 생활에 불편한 정도의 보상성 다한증은 30례(31.9%) 였다. 수술의 만족도는 95.8%에서 만족한다고 하였으며 4.2%에서 만족하지 못한다고 하였다. 4.2%의 환자에서 수술은 성공적이나 수술후 합병증에 대한 불편함 때문에 만족하지 못한다고 하였다. 이에 대해 수술전 환자의 선택에 있어서 보상성 다한증에 대한 설명이 꼭 필요할것으로 생각되어진다. 본 연세대학교 영동세브란스 병원에서는 1997년 6월부터 1997년 10월까지 2 mm흉강경을 이용한 다한증치료를 하였기에 임상 고찰과 함께 보고하는 바이다.

• Journal of Chest Surgery
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• 제23권2호
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• pp.299-308
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• 1990

A review of 50 patients with primary mediastinal tumors or cysts has been done to evaluate clinical and pathological behavior of this heterogeneous group of tumors proved by either excision or biopsy from January 1980 to August 1989 at the cardiovascular department of surgery in Kyungpook National University Hospital. There were 30 males and 20 females in this series. The ages of patients ranged from 4 months to 64 years. The mean age of subjects was 30.4 years. Neurogenic tumors [14 cases, 28%] and teratoma [14 cases, 28%] were most frequently encountered and followed by thymoma [10 cases, 20%] and benign cysts [4 cases, 8%]. The anatomic location of the primary mediastinal tumors or cysts was classified as anterior mediastinum and middle or visceral mediastinum and paravertebral or costovertebral mediastinum on the basis of the Shields’ proposition. In 32 patients[64%], the tumors or cysts were located in anterior mediastinum and in 13 patients[26%], the tumors or cysts were located in paravertebral or costovertebral mediastinum. And the rest 5 patients[10%] had middle or visceral mediastinal tumors or cysts. One of the characteristic features of primary mediastinal tumors or cysts is that some mediastinal tumors or cysts have their own preferred location in the mediastinum. In our series, all of the 14 patients with teratoma and 10 patients with thymoma had the anterior mediastinal location, while 13 of the 14 patients with neurogenic tumors had the paravertebral mediastinal location. 14 patients[28%] were asymptomatic and they all were discovered via so-called “Routine” chest x-ray examination. 39 of 50 patients[78%] were benign. 11 patients[22%] were malignant and they were all symptomatic. 40 patients[80%] were treated with complete resection. 5 patients[10%] were treated with partial resection : 2 of malignant thymoma, 3 of lipoma, neuroblastoma, primary squamous cell carcinoma. The rest 5 patients[10%] were only biopsied: 2 of undetermined malignancy and 3 of hemangioma, lymphoma, primary squamous cell carcinoma. 4 of the 10 patients were treated with combination of irradiation and chemotherapy. Postoperative complications were as followings: Horner’s syndrome [4cases, ado], respiratory failure [3 cases, 6%], pleural effusion[3 cases, 6%], Wound infection[2 cases, 4%] and bleeding, pneumothorax, empyema. There were 5 postoperative deaths [10%]. One patient with neuroblastoma died from intraoperative massive bleeding, 3 patients died early postoperatively from respiratory failure with undetermined malignancy died late postoperatively from congestive heart failure due to direct invasion of the tumor to the heart.

• Journal of Chest Surgery
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• 제31권10호
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• pp.999-1003
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• 1998

연구배경 : 수장부 다한증에 대한 흉강경 교감신경절차단술은 즉각적으로 증상을 호전시키고 회복시킨다는 장점을 갖고 있다. 그러나 수장부 다한증에서의 차단해야할 교감신경절의 위치는 다소 모호한 것이 사실이었다 재료 및 방법 : 제 2 및 2.3 흉부 교감신경절차단의 효과를 비교하기위하여 본 서울대학교 흉부외과학 교실에서는 1994년 4월부터 1997년 7월까지 제 2흉부교감신경절차단술 혹은 제2.3 흉부교감신경절차단술을 시행받은 192명의 일차성 수장부 다한증환자를 대상으로 역향성 연구를 시행하였다. 두 그룹간의 결과를 비교하기위하여 환자의 술전,후 의무기록 및 외래관찰소견을 참조하였으며 전화질의를 통하여 두 군간의 술후 증상의 변화를 조사하였다. 두 군간의 성비및 연령에는 통계적 차이가 없었다. 1997년 4월이전에는 교감신경절제술(sympathectomy)을 시행하였으나 이후로는 교감신경절차단술(sympathicotomy)을 시행하고 있다. 결과 : 술후 모든환자에서 증상의 즉각적인 완화를 보였다. 평균 수술시간은 제 2 흉부 교감신경절차단군에서 61.3$\pm$22.5분으로 제2.3 교감신경절차단군의 82.7$\pm$24.8분에 비해 통계적으로 유의하게 짧았다(p<0.01). 술후 호너증후군과 흉관삽관술과 같은 초기합병증의 빈도는 두 군간의 유의한 차이가 없었다. 보상성 체간다한증, 식사시 발한, 환다한증과 같은 후기 합병증의 빈도에서도 두 군간의 통계적 차이는 없었다. 재발한 례는 제 2, 및 2.3 흉부 교감신경절차단군 모두에서 한 명도 없었다. 보상성 다한증의 위치는 두 군간의 차이를 보여 제 2 흉부 교감신경절차단군에서는 무릎위에서 겨드랑이 까지 발한의 증가를 보였으나 제 2.3 흉부 교감신경절 차단군에서는 무릎위에서 유두부위까지 발한의 증가를 보이는 소견을 보였다. 결론 : 결론적으로 일차성 수장부 다한증에서는 제 2 흉부 교감신경절 차단술만으로도 충분한 효과를 얻을 수있다고 하겠다.

• Journal of Chest Surgery
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• 제31권3호
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• pp.279-285
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• 1998

손과 발에 정상 이상의 많은 땀이 나는 것은 정신적으로나 직업적으로 난처하고 때로는 무력한 상태를 만든다. 다한증은 자율신경계의 흔한 질병중 하나이다. 다한증은 특별한 치료법이 없었으며 따라서 액와 또는 경부 쪽에서 접근하는 절제술이 있었다. 최근에는 흉강경을 이용한 흉부수술(VATS)이 수장부와 액와부의 다한증에 가장 널리 사용되고 있다. 경희의료원에서는 1996년 3월부터 1997년 3월까지 양쪽 수장부에 다한증이 있는 15명의 환자를 양측 흉부 교감신경 절제술 (T2, T3, T4)을 시행하였고, 수술 전후로 컴퓨터 적외선 전신 체열 측정 (DITI)을 하였다. 이들 모두 개흉술로의 전환은 없었다. 3건의 술후 합병증으로 폐부종 1건, Horner씨 증후군 1건, 미각 다한증 1례가 있었다. 반 이상의 환\ulcorner에서 하복부, 둔부,배부, 대퇴부에 보상성 다한증이 나타났다. 결론적으로, 대부분의 환자는 수장부와 액와부에 땀이 나지 않고, 통증이 적고, 미용상 더 낫고, 족저부와 안면부에도 땀이 줄어 흉강경 수술 후의 결과에 대해 만족하였다. 또한 수술중에 수장부 온도를 측정함으로써 흉강경 교감신경 절제술의 성공 여부를 평가할 수 있었으며, 컴퓨터 적외선 체열 측정을 수술 전후로 시행함으로써 이 방법이 흉강경 교감신경 절제술의 성공적인 결과를 평가하는 객관적인 방법이 될 수 있었다고 사려된다.