• Title/Summary/Keyword: Homoepibatidine

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Syntheses of ($\pm$)-Homoepibatidine Analogues

  • Kim, Yong-Hyun;Oh, Chang-Young;Lee, Kee-Young;Lee, Yiu-Suk;Jung, Young-Hoon;Park, Hyun-Ju;Ham, Won-Hun
    • Archives of Pharmacal Research
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    • v.25 no.1
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    • pp.49-52
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    • 2002
  • Syntheses of ($\pm$)-homoepibatidine analogues (2), which contain the 8-azabicyclo [3.2.1 ]octane ring system, were achieved by using palladium-catalyzed reductive-coupling reaction from 3 and the analgesic activity was tested by Mouse writhing antinociceptive assay

Total Synthesis of ($\pm$)-Homoepibatidine

  • Kim, Yong-Hyun;Won, Do-Youn;Oh, Chang-Young;Lee, Kee-Young;Jeong, Jin-Hyun;Jung, Young-Hoon;Ham, Won-Hun
    • Archives of Pharmacal Research
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    • v.22 no.4
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    • pp.435-436
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    • 1999
  • Total synthesis of ($\pm$)-homoepibatidine (2), which contains the 8-azabicyclo[3.2.1] octane ring system, was achieved by using palladium-catalyzed Heck-type coupling reaction from 3.

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